scholarly article | Q13442814 |
P50 | author | Quansheng Du | Q55117832 |
Jeremy L Balsbaugh | Q56876779 | ||
Jeffrey Shabanowitz | Q28219914 | ||
P2093 | author name string | Ian G Macara | |
Xinyu Chen | |||
Donald F Hunt | |||
Yi Hao | |||
Zhen Zheng | |||
Sushmit Maitra | |||
P2860 | cites work | Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors | Q41669104 |
Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system | Q42511782 | ||
Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts | Q47070895 | ||
Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells | Q47921771 | ||
aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity | Q24301746 | ||
Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins | Q24313402 | ||
The Cdc42 GEF Intersectin 2 controls mitotic spindle orientation to form the lumen during epithelial morphogenesis. | Q24313482 | ||
Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts | Q24670347 | ||
PDZ domain-mediated interaction of rabbit podocalyxin and Na(+)/H(+) exchange regulatory factor-2 | Q28216924 | ||
Tuba, a Cdc42 GEF, is required for polarized spindle orientation during epithelial cyst formation | Q30434136 | ||
The PAR proteins: fundamental players in animal cell polarization | Q30434403 | ||
LGN regulates mitotic spindle orientation during epithelial morphogenesis | Q30434467 | ||
Par-3 controls tight junction assembly through the Rac exchange factor Tiam1. | Q30436000 | ||
Methods for analyzing peptides and proteins on a chromatographic timescale by electron-transfer dissociation mass spectrometry | Q30436361 | ||
The Par3/aPKC interaction is essential for end bud remodeling and progenitor differentiation during mammary gland morphogenesis | Q30437640 | ||
Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly | Q30439656 | ||
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis | Q30484554 | ||
aPKC phosphorylation of Bazooka defines the apical/lateral border in Drosophila epithelial cells | Q33914394 | ||
From cells to organs: building polarized tissue. | Q34066373 | ||
Return of the GDI: the GoLoco motif in cell division. | Q34326049 | ||
Adaptation of core mechanisms to generate cell polarity | Q35109711 | ||
Podocyte cytoskeleton is connected to the integral membrane protein podocalyxin through Na+/H+-exchanger regulatory factor 2 and ezrin | Q35623942 | ||
Asymmetric cell division in C. elegans: cortical polarity and spindle positioning | Q35912817 | ||
Drosophila neuroblast asymmetric cell division: recent advances and implications for stem cell biology | Q36525282 | ||
Mechanisms of asymmetric stem cell division | Q37092865 | ||
Mechanisms of asymmetric cell division: flies and worms pave the way. | Q37145878 | ||
Spindle orientation during asymmetric cell division | Q37428762 | ||
The polarity-inducing kinase Par-1 controls Xenopus gastrulation in cooperation with 14-3-3 and aPKC. | Q38337110 | ||
Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells | Q39797461 | ||
P433 | issue | 20 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phosphorylation | Q242736 |
P304 | page(s) | 1809-1818 | |
P577 | publication date | 2010-10-07 | |
P1433 | published in | Current Biology | Q1144851 |
P1476 | title | Par3 controls epithelial spindle orientation by aPKC-mediated phosphorylation of apical Pins | |
P478 | volume | 20 |
Q42963092 | A NudE/14-3-3 pathway coordinates dynein and the kinesin Khc73 to position the mitotic spindle |
Q38744723 | A holey pursuit: lumen formation in the developing kidney |
Q34854496 | A lateral belt of cortical LGN and NuMA guides mitotic spindle movements and planar division in neuroepithelial cells |
Q28283309 | A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice |
Q89108028 | Aberrant endocytosis leads to the loss of normal mitotic spindle orientation during epithelial glandular morphogenesis |
Q47105968 | Activation of Discs large by aPKC aligns the mitotic spindle to the polarity axis during asymmetric cell division. |
Q27684030 | Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes |
Q42514276 | Afadin orients cell division to position the tubule lumen in developing renal tubules |
Q38004611 | An oblique view on the role of spindle orientation in vertebrate neurogenesis. |
Q38331631 | Asymmetric cell division in the Drosophila bristle lineage: from the polarization of sensory organ precursor cells to Notch-mediated binary fate decision |
Q27305890 | Atypical protein kinase C induces cell transformation by disrupting Hippo/Yap signaling |
Q37204613 | Breaking the epithelial polarity barrier in cancer: the strange case of LKB1/PAR-4 |
Q35780286 | Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice |
Q36525471 | Cell Fate Decision Making through Oriented Cell Division |
Q38677606 | Cell adhesion molecule control of planar spindle orientation. |
Q26858973 | Cell division and the maintenance of epithelial order |
Q37562683 | Cell division orientation is coupled to cell-cell adhesion by the E-cadherin/LGN complex |
Q37204597 | Cell polarity in morphogenesis and metastasis |
Q92615954 | Cell shape and intercellular adhesion regulate mitotic spindle orientation |
Q26785528 | Connections between cadherin-catenin proteins, spindle misorientation, and cancer |
Q90060993 | Control of Intestinal Cell Fate by Dynamic Mitotic Spindle Repositioning Influences Epithelial Homeostasis and Longevity |
Q30579254 | Cytokinesis defines a spatial landmark for hepatocyte polarization and apical lumen formation. |
Q42029608 | Discs large links spindle orientation to apical-basal polarity in Drosophila epithelia |
Q35041609 | Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation |
Q54479992 | Divergent lymphocyte signalling revealed by a powerful new tool for analysis of time-lapse microscopy. |
Q97597495 | Diversity of activator of G-Protein signaling (AGS)-family proteins and their impact on asymmetric cell division across taxa |
Q30587026 | Dlg1 controls planar spindle orientation in the neuroepithelium through direct interaction with LGN. |
Q38536445 | Dynamic localization of C. elegans TPR-GoLoco proteins mediates mitotic spindle orientation by extrinsic signaling. |
Q38309176 | Dynamic membrane patterning, signal localization and polarity in living cells. |
Q36884672 | Dynamin Binding Protein (Tuba) Deficiency Inhibits Ciliogenesis and Nephrogenesis in Vitro and in Vivo |
Q58768354 | E-cadherin bridges cell polarity and spindle orientation to ensure prostate epithelial integrity and prevent carcinogenesis in vivo |
Q38797377 | EGFR controls IQGAP basolateral membrane localization and mitotic spindle orientation during epithelial morphogenesis |
Q41374143 | Ect2/Pbl acts via Rho and polarity proteins to direct the assembly of an isotropic actomyosin cortex upon mitotic entry |
Q91168629 | Elevated leptin disrupts epithelial polarity and promotes premalignant alterations in the mammary gland |
Q90622869 | Emergence of Embryo Shape During Cleavage Divisions |
Q26851833 | Emerging role of cell polarity proteins in breast cancer progression and metastasis |
Q91942694 | Eph signaling controls mitotic spindle orientation and cell proliferation in neuroepithelial cells |
Q37968480 | Epithelial cell polarity, stem cells and cancer |
Q26864115 | Epithelial homeostasis |
Q38142056 | Epithelial polarity and spindle orientation: intersecting pathways |
Q26825041 | Epithelial polarity--generating and integrating signals from the ECM with integrins |
Q38676446 | Epithelial spindle orientation diversities and uncertainties: recent developments and lingering questions |
Q30538070 | Evidence for dynein and astral microtubule-mediated cortical release and transport of Gαi/LGN/NuMA complex in mitotic cells |
Q50627126 | FAK transduces extracellular forces that orient the mitotic spindle and control tissue morphogenesis. |
Q42514781 | Fibroblast-derived HGF drives acinar lung cancer cell polarization through integrin-dependent RhoA-ROCK1 inhibition. |
Q35907043 | Galpha/LGN-mediated asymmetric spindle positioning does not lead to unequal cleavage of the mother cell in 3-D cultured MDCK cells |
Q26799650 | Genes Regulating Epithelial Polarity Are Critical Suppressors of Esophageal Oncogenesis |
Q90504548 | Girdin is a component of the lateral polarity protein network restricting cell dissemination |
Q38091661 | Going vertical: functional role and working principles of the protein Inscuteable in asymmetric cell divisions |
Q37880248 | Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif. |
Q24298323 | Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho-protein-binding modules |
Q35569313 | How signaling between cells can orient a mitotic spindle. |
Q38254534 | How to be at the right place at the right time: the importance of spindle positioning in embryos |
Q46344926 | Human tumour viruses and the deregulation of cell polarity in cancer |
Q27312162 | Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKC |
Q34328511 | In vivo conditions to identify Prkci phosphorylation targets using the analog-sensitive kinase method in zebrafish. |
Q30699180 | Influence of cell polarity on early development of the sea urchin embryo |
Q88688776 | Insane in the apical membrane: Trafficking events mediating apicobasal epithelial polarity during tube morphogenesis |
Q27676217 | Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions |
Q36030193 | JAM-A regulates cortical dynein localization through Cdc42 to control planar spindle orientation during mitosis. |
Q92020476 | Junctional tumor suppressors interact with 14-3-3 proteins to control planar spindle alignment |
Q35785445 | LGN Directs Interphase Endothelial Cell Behavior via the Microtubule Network |
Q40693934 | LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development |
Q27671529 | LGN/mInsc and LGN/NuMA Complex Structures Suggest Distinct Functions in Asymmetric Cell Division for the Par3/mInsc/LGN and Gαi/LGN/NuMA Pathways |
Q64244563 | Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in S2 Cells |
Q42291770 | Lineage Specification from Prostate Progenitor Cells Requires Gata3-Dependent Mitotic Spindle Orientation |
Q30416351 | Loss of the Par3 polarity protein promotes breast tumorigenesis and metastasis |
Q35221604 | Loss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-κB/interleukin-6 (IL-6) axis in mouse mammary cells |
Q52313809 | MISP regulates the IQGAP1/Cdc42 complex to collectively orchestrate spindle orientation and mitotic progression. |
Q38240371 | Mammalian aPKC/Par polarity complex mediated regulation of epithelial division orientation and cell fate |
Q64103888 | Mechanisms of Spindle Positioning: Lessons from Worms and Mammalian Cells |
Q38779098 | Mechanistic basis of MAGUK-organized complexes in synaptic development and signalling |
Q38066193 | Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles. |
Q38792952 | Microtubules, polarity and vertebrate neural tube morphogenesis. |
Q35640283 | Mitotic Control of Planar Cell Polarity by Polo-like Kinase 1 |
Q42741255 | Mitotic Spindle Positioning in the EMS Cell of Caenorhabditis elegans Requires LET-99 and LIN-5/NuMA. |
Q37863911 | Molecular basis for endothelial lumen formation and tubulogenesis during vasculogenesis and angiogenic sprouting |
Q26996223 | Molecular mechanisms controlling vascular lumen formation in three-dimensional extracellular matrices |
Q39016064 | Molecular mechanisms of asymmetric divisions in mammary stem cells. |
Q27025216 | Molecular pathways regulating mitotic spindle orientation in animal cells |
Q37837188 | Molecular regulation of lumen morphogenesis. |
Q36343832 | Mouse Crumbs3 sustains epithelial tissue morphogenesis in vivo |
Q38799056 | Mouse inscuteable induces apical-basal spindle orientation to facilitate intermediate progenitor generation in the developing neocortex |
Q30513859 | Myosin-X functions in polarized epithelial cells |
Q42632502 | Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganization in solid cancers |
Q35992736 | Nuclear fallout provides a new link between aPKC and polarized cell trafficking. |
Q37846966 | On the cutting edge: post-translational modifications in cytokinesis |
Q38043462 | On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN. |
Q38197884 | Organization and execution of the epithelial polarity programme |
Q37425927 | PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position |
Q41563028 | PTEN controls glandular morphogenesis through a juxtamembrane β-Arrestin1/ARHGAP21 scaffolding complex |
Q27333195 | Pak1 regulates the orientation of apical polarization and lumen formation by distinct pathways |
Q27316277 | Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytes |
Q37267940 | Par1b links lumen polarity with LGN-NuMA positioning for distinct epithelial cell division phenotypes. |
Q47747110 | Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1. |
Q34155815 | Par3-mInsc and Gαi3 cooperate to promote oriented epidermal cell divisions through LGN. |
Q28487991 | Phenotypical analysis of atypical PKCs in vivo function display a compensatory system at mouse embryonic day 7.5 |
Q42407556 | Pins is not required for spindle orientation in the Drosophila wing disc |
Q26830318 | Polarity in mammalian epithelial morphogenesis |
Q92265679 | Polarity signaling ensures epidermal homeostasis by coupling cellular mechanics and genomic integrity |
Q37267919 | Polarity, cell division, and out-of-equilibrium dynamics control the growth of epithelial structures |
Q51735095 | Protein kinase C zeta suppresses low- or high-grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring. |
Q35701372 | Regulation of NDR1 activity by PLK1 ensures proper spindle orientation in mitosis |
Q37885469 | Regulation of asymmetric cell division in the epidermis |
Q38901748 | Regulation of mitotic spindle orientation: an integrated view. |
Q30514271 | Regulation of myosin activation during cell-cell contact formation by Par3-Lgl antagonism: entosis without matrix detachment |
Q37537542 | Regulation of polarized morphogenesis by protein kinase C iota in oncogenic epithelial spheroids. |
Q38196268 | Rewiring cell polarity signaling in cancer |
Q42505499 | Ric-8A, an activator protein of Gαi, controls mammalian epithelial cell polarity for tight junction assembly and cystogenesis |
Q58565715 | Role of G-proteins and S/T phosphorylation sites in the transition of Activator of G-Protein signaling 3 to cell puncta |
Q26829174 | Spindle orientation in mammalian cerebral cortical development |
Q34216354 | Spindle orientation: what if it goes wrong? |
Q30783287 | Square Cell Packing in the Drosophila Embryo through Spatiotemporally Regulated EGF Receptor Signaling |
Q58035193 | Structure and function of the guanylate kinase-like domain of the MAGUK family scaffold proteins |
Q54343794 | Sustained Wnt/β-catenin signalling causes neuroepithelial aberrations through the accumulation of aPKC at the apical pole. |
Q42464662 | Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages |
Q39242330 | Symmetry Does not Come for Free: Cellular Mechanisms to Achieve a Symmetric Cell Division. |
Q30741759 | The 14-3-3 protein PAR-5 regulates the asymmetric localization of the LET-99 spindle positioning protein. |
Q34345692 | The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells |
Q30850728 | The Light Intermediate Chain 2 Subpopulation of Dynein Regulates Mitotic Spindle Orientation |
Q36301305 | The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells |
Q37736437 | The Par3 polarity protein is an exocyst receptor essential for mammary cell survival |
Q36528106 | The Shp2-induced epithelial disorganization defect is reversed by HDAC6 inhibition independent of Cdc42 |
Q91753617 | The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia |
Q30417702 | The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold. |
Q59349302 | Upsetting the Balance: When Viruses Manipulate Cell Polarity Control |
Q28590637 | Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation |
Q38734544 | ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture. |
Q35839775 | aPKC phosphorylates JAM-A at Ser285 to promote cell contact maturation and tight junction formation |
Q45204952 | aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division. |
Q55513177 | aPKC: the Kinase that Phosphorylates Cell Polarity. |
Q37180589 | aPKCλ controls epidermal homeostasis and stem cell fate through regulation of division orientation |
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