Myosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions.

scientific article published on 19 October 2016

Myosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/164_2016_29
P698PubMed publication ID27757761

P2093author name stringFolma Buss
John Kendrick-Jones
Thomas A Masters
P2860cites workMyosin-V is a processive actin-based motorQ22003739
The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23Q22010266
Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosisQ24291429
Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiationQ24293236
Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosisQ24294756
MyRIP, a novel Rab effector, enables myosin VIIa recruitment to retinal melanosomesQ24294793
A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transportQ24295585
From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30Q24298272
A unique ATP hydrolysis mechanism of single-headed processive myosin, myosin IXQ24298446
Determination of human myosin III as a motor protein having a protein kinase activityQ24299160
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
FERM domain-containing unconventional myosin VIIA interacts with integrin β5 subunit and regulates αvβ5-mediated cell adhesion and migrationQ24300327
Myo1e binds anionic phospholipids with high affinityQ24300535
Myosin VI and its interacting protein LMTK2 regulate tubule formation and transport to the endocytic recycling compartment.Q24301155
Expression and localization of myosin-1d in the developing nervous systemQ24303720
Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitinQ24305560
Structural basis of cargo recognition by the myosin-X MyTH4-FERM domainQ24305586
A new compartment at stereocilia tips defined by spatial and temporal patterns of myosin IIIa expressionQ24305683
Myosin16b: The COOH-tail region directs localization to the nucleus and overexpression delays S-phase progressionQ24306338
Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi networkQ24306386
Functional characterization of the human myosin-7a motor domainQ24306911
Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell typesQ24313272
Defective myosin VIIA gene responsible for Usher syndrome type 1BQ24314638
Functional characterization of human myosin-18A and its interaction with F-actin and GOLPH3Q24320340
GOLPH3 bridges phosphatidylinositol-4- phosphate and actomyosin to stretch and shape the Golgi to promote buddingQ24336708
Myosin 1G (Myo1G) is a haematopoietic specific myosin that localises to the plasma membrane and regulates cell elasticityQ24336738
Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundleQ24337137
Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomesQ24338154
NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neuronsQ24338593
MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancerQ24535826
Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1BQ24562934
Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complexQ24597349
A millennial myosin censusQ24633678
Myosin Vb mobilizes recycling endosomes and AMPA receptors for postsynaptic plasticityQ24655632
An actin molecular treadmill and myosins maintain stereocilia functional architecture and self-renewalQ24676711
A role for myosin VI in postsynaptic structure and glutamate receptor endocytosisQ24678935
Myosin-X and diseaseQ26825835
The many different cellular functions of MYO7A in the retinaQ27005972
Small-molecule inhibitors of myosin proteinsQ27027635
Actin structure-dependent stepping of myosin 5a and 10 during processive movementQ27306218
Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin CloudsQ27314555
Control of directed cell migration in vivo by membrane-to-cortex attachmentQ27322747
The loop2 insertion of type IX myosin acts as an electrostatic actin tether that permits processive movementQ27334469
Myosin-VIIb, a novel unconventional myosin, is a constituent of microvilli in transporting epithelia.Q30168113
The ATPase activity of Myr3, a rat myosin I, is allosterically inhibited by its own tail domain and by Ca2+ binding to its light chain calmodulinQ30176165
A novel mammalian myosin I from rat with an SH3 domain localizes to Con A-inducible, F-actin-rich structures at cell-cell contactsQ30193460
Myo19 ensures symmetric partitioning of mitochondria and coupling of mitochondrial segregation to cell division.Q30274631
Fast adaptation in vestibular hair cells requires myosin-1c activityQ30437793
Signal transduction and regulation in smooth muscleQ30465812
Dimerized Drosophila myosin VIIa: a processive motorQ30477237
The ternary Rab27a-Myrip-Myosin VIIa complex regulates melanosome motility in the retinal pigment epitheliumQ30479761
Cadherin-23, myosin VIIa and harmonin, encoded by Usher syndrome type I genes, form a ternary complex and interact with membrane phospholipidsQ30479852
Myosin-10 and actin filaments are essential for mitotic spindle functionQ30482632
A myosin motor that selects bundled actin for motilityQ30482736
Myosin IIIa boosts elongation of stereocilia by transporting espin 1 to the plus ends of actin filamentsQ30490501
The structure of the myosin VI motor reveals the mechanism of directionality reversalQ30490997
Identification of MYO18A as a novel interacting partner of the PAK2/betaPIX/GIT1 complex and its potential function in modulating epithelial cell migration.Q30492846
Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundleQ30493544
Single-molecule stepping and structural dynamics of myosin X.Q30494681
Myosin-X induces filopodia by multiple elongation mechanismQ30494868
Head of myosin IX binds calmodulin and moves processively toward the plus-end of actin filamentsQ30495863
Structured post-IQ domain governs selectivity of myosin X for fascin-actin bundlesQ30496161
Myosin-dependent targeting of transmembrane proteins to neuronal dendritesQ30496554
Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.Q30497821
Myosin-X is required for cranial neural crest cell migration in Xenopus laevisQ30497957
Cargo binding activates myosin VIIA motor function in cellsQ30499937
Myosin-X functions in polarized epithelial cellsQ30513859
Myo1c regulates lipid raft recycling to control cell spreading, migration and Salmonella invasionQ30514215
Differential regulation of myosin X movements by its cargos, DCC and neogenin.Q30514794
Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosomeQ30525665
MYO1E mutations and childhood familial focal segmental glomerulosclerosisQ30541167
Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distancesQ30544040
Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.Q30572690
Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells.Q30576361
Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spreadQ30581595
Unconventional myosin Myo1c promotes membrane fusion in a regulated exocytic pathwayQ30592846
Myosin-1a is critical for normal brush border structure and compositionQ28512472
Glucose transporter recycling in response to insulin is facilitated by myosin Myo1cQ28512823
The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cellsQ28513409
Deficiency of Myo18B in mice results in embryonic lethality with cardiac myofibrillar aberrationsQ28513411
Myosin VIIa and sans localization at stereocilia upper tip-link density implicates these Usher syndrome proteins in mechanotransductionQ28569812
Kinetic mechanism of myosin IXB and the contributions of two class IX-specific regionsQ28571384
Large scale protein identification in intracellular aquaporin-2 vesicles from renal inner medullary collecting ductQ28571573
Actin and myosin-dependent localization of mRNA to dendritesQ28572457
Rat myr 4 defines a novel subclass of myosin I: identification, distribution, localization, and mapping of calmodulin-binding sites with differential calcium sensitivityQ28574546
Myosin Vb controls biogenesis of post-Golgi Rab10 carriers during axon developmentQ28577414
Regulation of myosin-VI targeting to endocytic compartmentsQ28580721
Role of myosin VI in the differentiation of cochlear hair cellsQ28585164
The motor protein myosin 1G functions in FcγR-mediated phagocytosisQ28585625
Mouse myosin-19 is a plus-end-directed, high-duty ratio molecular motorQ28585827
Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heartQ28592397
Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motilityQ28592732
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereociliaQ28593953
Detection of rare antigen-presenting cells through T cell-intrinsic meandering motility, mediated by Myo1g.Q28594611
Mechanism of adenosine triphosphate hydrolysis by actomyosinQ29396569
Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localizationQ29615477
A FERM domain autoregulates Drosophila myosin 7a activityQ30157340
The mechanism of pentabromopseudilin inhibition of myosin motor activityQ27653333
Structure of MyTH4-FERM domains in myosin VIIa tail bound to cargoQ27666702
Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domainQ27666969
Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor ActivityQ27670463
Antiparallel coiled-coil-mediated dimerization of myosin XQ27673659
Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorQ27674679
Three-dimensional structure of myosin subfragment-1: a molecular motorQ27731679
Myosin X is a downstream effector of PI(3)K during phagocytosisQ28114999
Characterization of the human and mouse unconventional myosin XV genes responsible for hereditary deafness DFNB3 and shaker 2Q28115357
Human Myo19 is a novel myosin that associates with mitochondriaQ28115572
SP-R210 (Myo18A) Isoforms as Intrinsic Modulators of Macrophage Priming and ActivationQ28116165
Myosin Vc is a molecular motor that functions in secretory granule traffickingQ28117478
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenanceQ28155879
Dissecting temporal and spatial control of cytokinesis with a myosin II InhibitorQ28183531
A human homologue of Drosophila kelch associates with myosin-VIIa in specialized adhesion junctionsQ28211256
The mechanism of muscular contractionQ28237595
The autosomal recessive isolated deafness, DFNB2, and the Usher 1B syndrome are allelic defects of the myosin-VIIA geneQ28239757
Molecular motors: structural adaptations to cellular functionsQ28251722
Association of gene polymorphisms with chronic kidney disease in Japanese individualsQ28257175
Non-muscle myosin II takes centre stage in cell adhesion and migrationQ28262326
Molecular cloning and domain structure of human myosin-VIIa, the gene product defective in Usher syndrome 1BQ28294301
Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Q28504869
Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusionsQ28505690
Myosin X regulates netrin receptors and functions in axonal path-findingQ28506167
An actin-dependent mechanism for long-range vesicle transportQ28506739
PHR1, an integral membrane protein of the inner ear sensory cells, directly interacts with myosin 1c and myosin VIIaQ28507299
Myo10 in brain: developmental regulation, identification of a headless isoform and dynamics in neuronsQ28507574
Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neuronsQ28507993
Modulation of cell adhesion and motility in the immune system by Myo1fQ28508243
Myosin 1g regulates cytoskeleton plasticity, cell migration, exocytosis, and endocytosis in B lymphocytesQ28508531
Disruption of Myosin 1e promotes podocyte injuryQ28509726
Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctionsQ28511375
Isolation of a novel PDZ-containing myosin from hematopoietic supportive bone marrow stromal cell linesQ28511921
Podocyte-specific knockout of myosin 1e disrupts glomerular filtrationQ36312646
Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function In vivoQ36328552
Walking with myosin V.Q36354001
Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetesQ36410632
Tissue distribution and subcellular localization of mammalian myosin IQ36531927
What can myosin VI do in cells?Q36686696
A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cellsQ36717333
Mammalian myosin-18A, a highly divergent myosinQ36725141
The class V myosin motor, myosin 5c, localizes to mature secretory vesicles and facilitates exocytosis in lacrimal aciniQ36805329
Retinal gene therapy with a large MYO7A cDNA using adeno-associated virusQ36808032
Association of myosin I alpha with endosomes and lysosomes in mammalian cellsQ36864538
Cargo transport: molecular motors navigate a complex cytoskeletonQ37069629
Myosin V from head to tailQ37073565
Regulation of cytoplasmic and smooth muscle myosinQ37188229
The tail binds to the head-neck domain, inhibiting ATPase activity of myosin VIIAQ37208900
Cloning and characterization of myr 6, an unconventional myosin of the dilute/myosin-V familyQ37297817
Involvement of headless myosin X in the motility of immortalized gonadotropin-releasing hormone neuronal cellsQ37339182
Cargo binding induces dimerization of myosin VI.Q37366472
Myosin 3A kinase activity is regulated by phosphorylation of the kinase domain activation loop.Q37415650
Fine mapping on chromosome 13q32-34 and brain expression analysis implicates MYO16 in schizophreniaQ37584240
Proteome screening of pleural effusions identifies galectin 1 as a diagnostic biomarker and highlights several prognostic biomarkers for malignant mesotheliomaQ37623620
Myosin VI rewrites the rules for myosin motorsQ37755563
The neurodevelopmental implications of PI3K signalingQ37768062
The role of myosin V in exocytosis and synaptic plasticity.Q37809553
Regulation and control of myosin-I by the motor and light chain-binding domains.Q38064119
Myosin motors at neuronal synapses: drivers of membrane transport and actin dynamics.Q38088529
Myosin VI and its cargo adaptors - linking endocytosis and autophagyQ38115519
Identification of a MYO18A-PDGFRB fusion gene in an eosinophilia-associated atypical myeloproliferative neoplasm with a t(5;17)(q33-34;q11.2).Q38453348
Loss of functional MYO1C/myosin 1c, a motor protein involved in lipid raft trafficking, disrupts autophagosome-lysosome fusion.Q38924123
Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC.Q38938046
Myosin VI must dimerize and deploy its unusual lever arm in order to perform its cellular roles.Q38962635
Unconventional myosin ID is expressed in myelinating oligodendrocytesQ38987764
Discovery of omecamtiv mecarbil the first, selective, small molecule activator of cardiac Myosin.Q39155695
Inactivation of MYO5B promotes invasion and motility in gastric cancer cellsQ39434310
Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cellsQ30699149
Dynamics of cytoskeletal proteins during Fcgamma receptor-mediated phagocytosis in macrophagesQ30857092
Myosin X transports Mena/VASP to the tip of filopodia.Q31065358
Myosin domain evolution and the primary divergence of eukaryotesQ33222230
A force-dependent state controls the coordination of processive myosin VQ33223012
Vertebrate myosin VIIb is a high duty ratio motor adapted for generating and maintaining tensionQ33223992
Human myosin Vc is a low duty ratio nonprocessive motorQ33310247
The t(8;17)(p11;q23) in the 8p11 myeloproliferative syndrome fuses MYO18A to FGFR1.Q33365634
Coupling of two non-processive myosin 5c dimers enables processive stepping along actin filamentsQ33585953
Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low loadQ33607079
Myosin 1G is an abundant class I myosin in lymphocytes whose localization at the plasma membrane depends on its ancient divergent pleckstrin homology (PH) domain (Myo1PH).Q33726416
Myosin VI: an innovative motor that challenged the swinging lever arm hypothesisQ33809113
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodiaQ33840016
Comparison of genome-wide array genomic hybridization platforms for the detection of copy number variants in idiopathic mental retardationQ33856401
The motor and tail regions of myosin XV are critical for normal structure and function of auditory and vestibular hair cellsQ33911618
Cloning and chromosomal localization of a human class III myosinQ33913130
A myosin I isoform in the nucleusQ33921315
Leveraging the membrane - cytoskeleton interface with myosin-1.Q33965456
Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasisQ33994291
Motor domain-dependent localization of myo1b (myr-1).Q34087135
Novel mutations of MYO15A associated with profound deafness in consanguineous families and moderately severe hearing loss in a patient with Smith-Magenis syndromeQ34104260
A small-molecule inhibitor of skeletal muscle myosin II.Q34105257
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility.Q34115035
Chaperone-enhanced purification of unconventional myosin 15, a molecular motor specialized for stereocilia protein traffickingQ34120199
Rab11 family interacting protein 2 associates with Myosin Vb and regulates plasma membrane recyclingQ34155849
Genome structure and differential expression of two isoforms of a novel PDZ-containing myosin (MysPDZ) (Myo18A).Q34199087
Walking to work: roles for class V myosins as cargo transportersQ34238805
PtdIns (3,4,5) P3 recruitment of Myo10 is essential for axon developmentQ34271141
Azidoblebbistatin, a photoreactive myosin inhibitor.Q34278121
Intermolecular autophosphorylation regulates myosin IIIa activity and localization in parallel actin bundles.Q34285278
Myosin-1c, the hair cell's adaptation motorQ34300171
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
Lessons from border cell migration in the Drosophila ovary: A role for myosin VI in dissemination of human ovarian cancerQ34332205
Reduced expression of MYO18B, a candidate tumor-suppressor gene on chromosome arm 22q, in ovarian cancerQ34340330
Loss of myosin VI reduces secretion and the size of the Golgi in fibroblasts from Snell's waltzer miceQ39698975
Functional role of the extended loop 2 in the myosin 9b head for binding F-actinQ39908271
Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcriptionQ40019177
Alternatively spliced exon B of myosin Va is essential for binding the tail-associated light chain shared by dyneinQ40222323
Correlation between histone acetylation and expression of the MYO18B gene in human lung cancer cellsQ40564233
A monomeric myosin VI with a large working strokeQ40573331
Both calmodulin and the unconventional myosin Myr4 regulate membrane trafficking along the recycling pathway of MDCK cellsQ40826317
Ca(2+)-dependent regulation of the motor activity of myosin V.Q40861044
Myosin 18A coassembles with nonmuscle myosin 2 to form mixed bipolar filamentsQ41260479
The swinging lever-arm hypothesis of muscle contraction.Q41397050
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
Kinetic properties and small-molecule inhibition of human myosin-6.Q42032109
A Myosin V Inhibitor Based on Privileged Chemical ScaffoldsQ42109184
Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2.Q42155473
Phosphorylation of the kinase domain regulates autophosphorylation of myosin IIIA and its translocation in microvilliQ42173398
Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.Q42455765
Myosin-Va and dynamic actin oppose microtubules to drive long-range organelle transportQ42787767
HOMER2 binds MYO18B and enhances its activity to suppress anchorage independent growthQ42829829
Video imaging of walking myosin V by high-speed atomic force microscopy.Q42863053
Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.Q42953653
Novel association of hypertrophic cardiomyopathy, sensorineural deafness, and a mutation in unconventional myosin VI (MYO6).Q43073801
Class I myosin Myo1e regulates TLR4-triggered macrophage spreading, chemokine release, and antigen presentation via MHC class II.Q43104723
Effect of phosphorylation in the motor domain of human myosin IIIA on its ATP hydrolysis cycleQ43146291
Actin dynamics is essential for myosin-based transport of membrane organellesQ43243036
The gated gait of the processive molecular motor, myosin V.Q43820585
Human myosin XVBP is a transcribed pseudogeneQ43966036
The mechanism of myosin VI translocation and its load-induced anchoringQ44790017
Magnesium regulates ADP dissociation from myosin V.Q45173714
Genetic and epigenetic alterations of the candidate tumor-suppressor gene MYO18B, on chromosome arm 22q, in colorectal cancerQ45306839
Binding of the extreme carboxyl-terminus of PAK-interacting exchange factor β (βPIX) to myosin 18A (MYO18A) is required for epithelial cell migrationQ45421490
High density SNP association study of a major autism linkage region on chromosome 17.Q46126953
The Drosophila ninaC locus encodes two photoreceptor cell specific proteins with domains homologous to protein kinases and the myosin heavy chain headQ46199533
A three-way translocation of MLL, MLLT11, and the novel reciprocal partner gene MYO18A in a child with acute myeloid leukemiaQ46526983
Myosin X is a high duty ratio motorQ46551350
Load-dependent kinetics of myosin-V can explain its high processivityQ46650611
Human myosin Vc is a low duty ratio, nonprocessive molecular motor.Q46803460
Drosophila myosin VIIA is a high duty ratio motor with a unique kinetic mechanismQ46895770
The PDZ-containing unconventional myosin XVIIIA regulates embryonic muscle integrity in zebrafishQ47073522
Myosin 16 levels fluctuate during the cell cycle and are downregulated in response to DNA replication stress.Q51062791
A microtubule-binding myosin required for nuclear anchoring and spindle assembly.Q52560093
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation.Q52604153
Phospholipid-dependent regulation of the motor activity of myosin X.Q52612413
Manassantin B inhibits melanosome transport in melanocytes by disrupting the melanophilin-myosin Va interaction.Q52628289
The motorized RhoGAP myosin IXb (Myo9b) in leukocytes regulates experimental autoimmune encephalomyelitis induction and recovery.Q53531055
Rho GAP myosin IXa is a regulator of kidney tubule function.Q54261556
Brush border myosin Ia inactivation in gastric but not endometrial tumors.Q54290806
Regulation of non-muscle myosin assembly by calmodulin-dependent light chain kinase.Q54304184
Dendritic cell motility and T cell activation requires regulation of Rho-cofilin signaling by the Rho-GTPase activating protein myosin IXb.Q54367276
MYO15A (DFNB3) mutations in Turkish hearing loss families and functional modeling of a novel motor domain mutation.Q55044601
MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish populationQ56968885
TIRFing out Studies on Glut4 TraffickingQ58197148
The role of vertebrate nonmuscle Myosin II in development and human diseaseQ34362453
The N-terminal domain of MYO18A has an ATP-insensitive actin-binding site.Q34412033
para-Nitroblebbistatin, the non-cytotoxic and photostable myosin II inhibitorQ34426082
Griscelli disease maps to chromosome 15q21 and is associated with mutations in the myosin-Va geneQ34431158
Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3.Q34469642
Human myosin III is a motor having an extremely high affinity for actinQ34570448
Myosin vc interacts with Rab32 and Rab38 proteins and works in the biogenesis and secretion of melanosomesQ34580378
Loss-of-function of MYO5B is the main cause of microvillus inclusion disease: 15 novel mutations and a CaCo-2 RNAi cell model.Q34617207
Mutational spectrum of MYO15A: the large N-terminal extension of myosin XVA is required for hearing.Q34634062
MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity.Q34812873
Myo3A, one of two class III myosin genes expressed in vertebrate retina, is localized to the calycal processes of rod and cone photoreceptors and is expressed in the sacculusQ34813453
Molecular motors: force and movement generated by single myosin II moleculesQ34882785
Multiplying myosins.Q34943936
New insights into myosin evolution and classificationQ34944007
Pharmacological activation of myosin II paralogs to correct cell mechanics defects.Q35062582
Inhibition of smooth muscle myosin as a novel therapeutic target for hypertensionQ35265639
Autism and Intellectual Disability-Associated KIRREL3 Interacts with Neuronal Proteins MAP1B and MYO16 with Potential Roles in NeurodevelopmentQ35527346
Myosin-X: a MyTH-FERM myosin at the tips of filopodiaQ35576442
Myosin V motor proteins: marching stepwise towards a mechanismQ35580794
A novel role of myosin VI in human prostate cancerQ35607414
Melanophilin Stimulates Myosin-5a Motor Function by Allosterically Inhibiting the Interaction between the Head and Tail of Myosin-5aQ35679335
Relating biochemistry and function in the myosin superfamilyQ35705378
The cargo-binding domain regulates structure and activity of myosin 5Q35752269
Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctionsQ35785344
Coevolution of head, neck, and tail domains of myosin heavy chainsQ35817749
Structure and Regulation of the Movement of Human Myosin VIIA.Q35837241
Calmodulin bound to the first IQ motif is responsible for calcium-dependent regulation of myosin 5aQ35956753
Adenosine diphosphate and strain sensitivity in myosin motors.Q36007515
Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cellsQ36085245
The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearingQ36119739
Myosins: tails (and heads) of functional diversityQ36197820
Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I familyQ36233141
The molecular mechanism of muscle contraction.Q36288552
P304page(s)77-122
P577publication date2016-10-19
P1433published inHandbook of experimental pharmacologyQ26841924
P1476titleMyosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions.
P478volume235

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