Myosin-X and disease

scientific article

Myosin-X and disease is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1016/J.YEXCR.2015.03.014
P3181OpenCitations bibliographic resource ID3767018
P932PMC publication ID4433855
P698PubMed publication ID25819274

P50authorRichard CheneyQ42703433
P2093author name stringDavid S. Courson
P2860cites workMyosin-X is a molecular motor that functions in filopodia formationQ24299253
Structural basis of cargo recognition by the myosin-X MyTH4-FERM domainQ24305586
Defective myosin VIIA gene responsible for Usher syndrome type 1BQ24314638
Myosin-X: a MyTH-FERM myosin at the tips of filopodiaQ35576442
ATP-mediated Erk1/2 activation stimulates bacterial capture by filopodia, which precedes Shigella invasion of epithelial cellsQ35586337
Headless Myo10 is a negative regulator of full-length Myo10 and inhibits axon outgrowth in cortical neuronsQ36127036
The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusionsQ36162084
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptorsQ36639095
Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomesQ36843504
The SAH domain extends the functional length of the myosin leverQ37477144
The spatial and temporal dynamics of pleckstrin homology domain binding at the plasma membrane measured by imaging single molecules in live mouse myoblastsQ39674089
The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cellsQ39699837
Budding of Marburgvirus is associated with filopodiaQ40202125
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
The expression of fascin, an actin-bundling motility protein, correlates with hormone receptor-negative breast cancer and a more aggressive clinical course.Q45238909
EGFR mutation up-regulates EGR1 expression through the ERK pathwayQ47886467
Identification of molecular subtypes of glioblastoma by gene expression profilingQ48332534
Classification of pediatric acute lymphoblastic leukemia by gene expression profilingQ52017263
A microtubule-binding myosin required for nuclear anchoring and spindle assembly.Q52560093
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation.Q52604153
Phospholipid-dependent regulation of the motor activity of myosin X.Q52612413
The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head.Q52857621
Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domainQ27666969
Antiparallel coiled-coil-mediated dimerization of myosin XQ27673659
Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorQ27674679
Myosin X is a downstream effector of PI(3)K during phagocytosisQ28114999
Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancerQ28237051
Prognostic significance of fascin overexpression in human esophageal squamous cell carcinomaQ28243822
Filopodia: molecular architecture and cellular functionsQ28279460
Regulation of stereocilia length by myosin XVa and whirlin depends on the actin-regulatory protein Eps8Q28504869
Myosin X regulates netrin receptors and functions in axonal path-findingQ28506167
An integrin-linked machinery of cytoskeletal regulation that enables experimental tumor initiation and metastatic colonizationQ28593023
Mechanism of filopodia initiation by reorganization of a dendritic networkQ29616648
PI3K and cancer: lessons, challenges and opportunitiesQ30080017
Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent mannerQ30479119
The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation.Q30480576
Myosin-10 and actin filaments are essential for mitotic spindle functionQ30482632
A myosin motor that selects bundled actin for motilityQ30482736
An unconventional myosin required for cell polarization and chemotaxisQ30494552
Single-molecule stepping and structural dynamics of myosin X.Q30494681
Myosin-X induces filopodia by multiple elongation mechanismQ30494868
Myosin-X is required for cranial neural crest cell migration in Xenopus laevisQ30497957
Myosin-X functions in polarized epithelial cellsQ30513859
Live-cell imaging of Marburg virus-infected cells uncovers actin-dependent transport of nucleocapsids over long distancesQ30544040
Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.Q30572690
Myosin-X facilitates Shigella-induced membrane protrusions and cell-to-cell spreadQ30581595
Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomasQ33259830
Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low loadQ33607079
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodiaQ33840016
Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.Q33917620
Elevated expression of myosin X in tumours contributes to breast cancer aggressiveness and metastasisQ33994291
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility.Q34115035
The Stepping Pattern of Myosin X Is Adapted for Processive Motility on Bundled ActinQ34134758
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
Association of unconventional myosin MYO15 mutations with human nonsyndromic deafness DFNB3.Q34469642
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)10-5
P577publication date2015-05-15
P1433published inExperimental Cell ResearchQ1524289
P1476titleMyosin-X and disease
P478volume334

Reverse relations

cites work (P2860)
Q42515905A composite network of conserved and tissue specific gene interactions reveals possible genetic interactions in glioma.
Q37000324Competition between Coiled-Coil Structures and the Impact on Myosin-10 Bundle Selection
Q93257727Filopodia play an important role in the trans-mesothelial migration of ovarian cancer cells
Q42380606Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions
Q52689190Myosin 10 is involved in murine pigmentation.
Q47139973Myosin-X knockout is semi-lethal and demonstrates that myosin-X functions in neural tube closure, pigmentation, hyaloid vasculature regression, and filopodia formation.
Q51377017Myosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions.
Q38722191Structural Basis of Cargo Recognition by Unconventional Myosins in Cellular Trafficking
Q43058873Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins.
Q88202227The Antiparallel Dimerization of Myosin X Imparts Bundle Selectivity for Processive Motility
Q27333243The myosin X motor is optimized for movement on actin bundles
Q39462637Transcriptional Categorization of the Etiology of Pneumonia Syndrome in Pediatric Patients in Malaria-Endemic Areas

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