Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load

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Myosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load is …
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scholarly articleQ13442814

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P819ADS bibcode2014PNAS..111E1833T
P356DOI10.1073/PNAS.1320122111
P8608Fatcat IDrelease_7b4zhrsxuvdnri5v76am3npcqu
P932PMC publication ID4020102
P698PubMed publication ID24753602
P5875ResearchGate publication ID261772459

P50authorNeil BillingtonQ55711575
Justin E. MolloyQ60648629
P2093author name stringYi Yang
Attila Nagy
Yasuharu Takagi
James R Sellers
Christopher Batters
Rachel E Farrow
P2860cites workDrawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 speciesQ21092862
Myosin-V is a processive actin-based motorQ22003739
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
Myosin VI is a processive motor with a large step sizeQ24555089
Myo1c is designed for the adaptation response in the inner earQ24610102
Single-molecule measurement of the stiffness of the rigor myosin headQ24642486
Actin structure-dependent stepping of myosin 5a and 10 during processive movementQ27306218
X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coilQ27655682
Antiparallel coiled-coil-mediated dimerization of myosin XQ27673659
Myosin X is a downstream effector of PI(3)K during phagocytosisQ28114999
Kinetic mechanism of non-muscle myosin IIB: functional adaptations for tension generation and maintenanceQ28155879
Molecular motors: structural adaptations to cellular functionsQ28251722
Atomic model of the actin filamentQ28296802
Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cellsQ36796861
Fluorescent actin filaments move on myosin fixed to a glass surfaceQ37396490
Direct observation of the mechanochemical coupling in myosin Va during processive movementQ37416808
The SAH domain extends the functional length of the myosin leverQ37477144
Coiled coils and SAH domains in cytoskeletal molecular motorsQ37936477
The stiffness of rabbit skeletal actomyosin cross-bridges determined with an optical tweezers transducer.Q40128502
Mechanism of action of myosin X, a membrane-associated molecular motor.Q40459823
A monomeric myosin VI with a large working strokeQ40573331
Myosin I can act as a molecular force sensor.Q41334383
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
Elementary processes of the magnesium ion-dependent adenosine triphosphatase activity of heavy meromyosin. A transient kinetic approach to the study of kinases and adenosine triphosphatases and a colorimetric inorganic phosphate assay in situQ42924643
The gated gait of the processive molecular motor, myosin V.Q43820585
Neck length and processivity of myosin V.Q44436395
Load-dependent kinetics of force production by smooth muscle myosin measured with optical tweezersQ44632341
Kinetics of ADP dissociation from the trail and lead heads of actomyosin V following the power strokeQ44933308
A model of myosin V processivityQ44978572
Mechanics of the kinesin step.Q46497531
Myosin X is a high duty ratio motorQ46551350
Step-size is determined by neck length in myosin V.Q47358625
Cooperation between the two heads of smooth muscle myosin is essential for full activation of the motor function by phosphorylationQ47774942
Phospholipid-dependent regulation of the motor activity of myosin X.Q52612413
The predicted coiled-coil domain of myosin 10 forms a novel elongated domain that lengthens the head.Q52857621
Two-headed binding of a processive myosin to F-actin.Q52863984
Using optical tweezers to study the fine details of myosin ATPase mechanochemical cycleQ56892167
The motor protein myosin-I produces its working stroke in two stepsQ56894963
Factors affecting movement of F-actin filaments propelled by skeletal muscle heavy meromyosinQ68077086
Probing the folding mechanism of a leucine zipper peptide by stopped-flow circular dichroism spectroscopyQ71715528
A conserved negatively charged amino acid modulates function in human nonmuscle myosin IIAQ73811675
Dimerization of the head-rod junction of scallop myosinQ77630486
Myosin X regulates netrin receptors and functions in axonal path-findingQ28506167
Myo10 in brain: developmental regulation, identification of a headless isoform and dynamics in neuronsQ28507574
Myosin V exhibits a high duty cycle and large unitary displacementQ28512626
Different degrees of lever arm rotation control myosin step sizeQ28573622
Control of myosin-I force sensing by alternative splicingQ28577567
Myosin V walks hand-over-hand: single fluorophore imaging with 1.5-nm localizationQ29615477
Dimerized Drosophila myosin VIIa: a processive motorQ30477237
Myosin-10 and actin filaments are essential for mitotic spindle functionQ30482632
A myosin motor that selects bundled actin for motilityQ30482736
Single-molecule stepping and structural dynamics of myosin X.Q30494681
Myosin-X induces filopodia by multiple elongation mechanismQ30494868
Structured post-IQ domain governs selectivity of myosin X for fascin-actin bundlesQ30496161
Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells.Q30576361
The light chain binding domain of expressed smooth muscle heavy meromyosin acts as a mechanical leverQ30652709
Myosin domain evolution and the primary divergence of eukaryotesQ33222230
Smooth muscle and skeletal muscle myosins produce similar unitary forces and displacements in the laser trapQ33915663
Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.Q33917620
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility.Q34115035
The Stepping Pattern of Myosin X Is Adapted for Processive Motility on Bundled ActinQ34134758
ADP inhibition of myosin V ATPase activityQ34173890
Walking to work: roles for class V myosins as cargo transportersQ34238805
Two independent mechanical events in the interaction cycle of skeletal muscle myosin with actinQ34248222
Movement and force produced by a single myosin head.Q34288654
Single myosin molecule mechanics: piconewton forces and nanometre stepsQ34338098
Force generation in single conventional actomyosin complexes under high dynamic loadQ34354132
Role of the lever arm in the processive stepping of myosin V.Q34392475
Myosin-V stepping kinetics: a molecular model for processivityQ35207228
Myosin-X: a MyTH-FERM myosin at the tips of filopodiaQ35576442
Relating biochemistry and function in the myosin superfamilyQ35705378
Myosin IC generates power over a range of loads via a new tension-sensing mechanism.Q36236371
Detection of single-molecule interactions using correlated thermal diffusionQ36297728
The prepower stroke conformation of myosin V.Q36325587
Kinetic characterization of nonmuscle myosin IIb at the single molecule levelQ36508784
P4510describes a project that usesImageJQ1659584
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectactin filamentQ329638
P304page(s)E1833-42
P577publication date2014-04-21
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMyosin-10 produces its power-stroke in two phases and moves processively along a single actin filament under low load
P478volume111

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cites work (P2860)
Q30826156A Combination of Diffusion and Active Translocation Localizes Myosin 10 to the Filopodial Tip
Q30841590Activated full-length myosin-X moves processively on filopodia with large steps toward diverse two-dimensional directions
Q34120199Chaperone-enhanced purification of unconventional myosin 15, a molecular motor specialized for stereocilia protein trafficking
Q37000324Competition between Coiled-Coil Structures and the Impact on Myosin-10 Bundle Selection
Q47119134Compositional and expression analyses of the glideosome during the Plasmodium life cycle reveal an additional myosin light chain required for maximum motility
Q61135840Dissecting myosin-5B mechanosensitivity and calcium regulation at the single molecule level
Q50943386Exclusion and Hierarchy of Time Scales Lead to Spatial Segregation of Molecular Motors in Cellular Protrusions.
Q38756098Kinetic Adaptations of Myosins for Their Diverse Cellular Functions
Q47141269Measuring the Kinetic and Mechanical Properties of Non-processive Myosins Using Optical Tweezers.
Q38803208Mechanics and Activation of Unconventional Myosins
Q92655586Myosin V executes steps of variable length via structurally constrained diffusion
Q41530183Myosin tails and single α-helical domains
Q26825835Myosin-X and disease
Q51377017Myosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions.
Q30588808Stable single α-helices are constant force springs in proteins
Q38722191Structural Basis of Cargo Recognition by Unconventional Myosins in Cellular Trafficking
Q35336045Structural dynamics of myosin 5 during processive motion revealed by interferometric scattering microscopy
Q88202227The Antiparallel Dimerization of Myosin X Imparts Bundle Selectivity for Processive Motility
Q27333243The myosin X motor is optimized for movement on actin bundles

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