Filopodia: molecular architecture and cellular functions

scientific article

Filopodia: molecular architecture and cellular functions is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1001840033
P356DOI10.1038/NRM2406
P3181OpenCitations bibliographic resource ID241082
P698PubMed publication ID18464790
P5875ResearchGate publication ID5386446

P50authorPekka LappalainenQ17382087
P2093author name stringPieta K Mattila
P2860cites workWound healing recapitulates morphogenesis in Drosophila embryosQ47070872
Growth cone steering by a physiological electric field requires dynamic microtubules, microfilaments and Rac-mediated filopodial asymmetry.Q51233436
A microtubule-binding myosin required for nuclear anchoring and spindle assembly.Q52560093
Essential role of filopodia in chemotropic turning of nerve growth cone induced by a glutamate gradientQ70891412
Evidence for fascin cross-links between the actin filaments in coelomocyte filopodiaQ71847923
A role for myosin VII in dynamic cell adhesionQ73670214
Ena/VASP Is Required for neuritogenesis in the developing cortexQ81565765
Cellular functions of TC10, a Rho family GTPase: regulation of morphology, signal transduction and cell growthQ22003723
The novel Rho-family GTPase rif regulates coordinated actin-based membrane rearrangementsQ24290533
Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complexQ24291871
Structural basis for the recruitment of profilin-actin complexes during filament elongation by Ena/VASP.Q24296423
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
IRSp53/Eps8 complex is important for positive regulation of Rac and cancer cell motility/invasivenessQ24300415
The atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamicsQ24304033
The RAC binding domain/IRSp53-MIM homology domain of IRSp53 induces RAC-dependent membrane deformationQ24304626
A novel actin bundling/filopodium-forming domain conserved in insulin receptor tyrosine kinase substrate p53 and missing in metastasis proteinQ24306756
Intrinsic dynamic behavior of fascin in filopodiaQ24328847
Structural basis of filopodia formation induced by the IRSp53/MIM homology domain of human IRSp53Q24557455
Filopodia act as phagocytic tentacles and pull with discrete steps and a load-dependent velocity.Q24677668
Ena/VASP proteins enhance actin polymerization in the presence of barbed end capping proteinsQ24678535
Structural basis for the actin-binding function of missing-in-metastasisQ24682067
Stress fibers are generated by two distinct actin assembly mechanisms in motile cellsQ24683694
Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cellsQ27333967
Lamellipodia nucleation by filopodia depends on integrin occupancy and downstream Rac1 signalingQ42819566
Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarityQ43108576
Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines.Q45957480
The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia.Q46503087
Filopodia are required for cortical neurite initiation.Q46891046
BAR domains as sensors of membrane curvature: the amphiphysin BAR structureQ27642663
Structure and analysis of FCHo2 F-BAR domain: a dimerizing and membrane recruitment module that effects membrane curvatureQ27645108
Cellular motility driven by assembly and disassembly of actin filamentsQ27860676
Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodiaQ27861126
The EVH2 domain of the vasodilator-stimulated phosphoprotein mediates tetramerization, F-actin binding, and actin bundle formationQ28141490
Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complexQ28142313
Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42Q28188673
WAVE2 serves a functional partner of IRSp53 by regulating its interaction with RacQ28203310
Small GTPase Tc10 and its homologue RhoT induce N-WASP-mediated long process formation and neurite outgrowthQ28216274
Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancerQ28237051
Rho GTPases and actin dynamics in membrane protrusions and vesicle traffickingQ28261534
Phylogenetic analysis of the formin homology 2 domainQ28290186
Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2/3 complexQ28293934
Mechanism and function of formins in the control of actin assemblyQ28293947
ABBA regulates plasma-membrane and actin dynamics to promote radial glia extensionQ28504992
Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complexQ28505970
Myosin X regulates netrin receptors and functions in axonal path-findingQ28506167
Mouse MIM, a tissue-specific regulator of cytoskeletal dynamics, interacts with ATP-actin monomers through its C-terminal WH2 domainQ28507602
Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cellsQ28576273
Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPasesQ28580747
NMDA receptor-dependent synaptic translocation of insulin receptor substrate p53 via protein kinase C signalingQ28582299
Mena is required for neurulation and commissure formationQ28588447
Actin pedestal formation by enteropathogenic Escherichia coli and intracellular motility of Shigella flexneri are abolished in N-WASP-defective cellsQ28590934
The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assemblyQ28609843
Mechanism of filopodia initiation by reorganization of a dendritic networkQ29616648
Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motilityQ29618423
Directed actin polymerization is the driving force for epithelial cell-cell adhesionQ29618861
The many faces of actin: matching assembly factors with cellular structuresQ29620433
Ena/VASP proteins capture actin filament barbed endsQ30439841
Ena/VASP proteins have an anti-capping independent function in filopodia formationQ30444426
Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cellsQ30476210
The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formationQ30477234
Filopodia formation in the absence of functional WAVE- and Arp2/3-complexesQ30477396
Initiation of attachment and generation of mature focal adhesions by integrin-containing filopodia in cell spreadingQ30478240
Optimization of WAVE2 complex-induced actin polymerization by membrane-bound IRSp53, PIP(3), and Rac.Q30480399
The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation.Q30480576
Dynamic analysis of filopodial interactions during the zippering phase of Drosophila dorsal closureQ30482461
Ena/VASP function in retinal axons is required for terminal arborization but not pathway navigationQ30549635
Rapid epithelial-sheet sealing in the Caenorhabditis elegans embryo requires cadherin-dependent filopodial primingQ30798313
Myosin X transports Mena/VASP to the tip of filopodia.Q31065358
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility.Q34115035
Requirement of a vasodilator-stimulated phosphoprotein family member for cell adhesion, the formation of filopodia, and chemotaxis in dictyosteliumQ34155214
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
Fascins, and their roles in cell structure and function.Q34596222
Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling propertiesQ34618647
Cellular control of actin nucleationQ34762557
Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.Q35564850
Regulation of growth cone actin filaments by guidance cuesQ35575896
Signaling and membrane dynamics during phagocytosis: many roads lead to the phagos(R)omeQ35840137
Wound healing and inflammation: embryos reveal the way to perfect repairQ35855738
Imaging myosin 10 in cellsQ35922809
Role of fascin in filopodial protrusionQ36118593
Ena/VASP is required for endothelial barrier function in vivoQ36149239
Myosin-X: a molecular motor at the cell's fingertipsQ36248392
Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retractionQ36316633
How VASP enhances actin-based motilityQ36324377
The making of filopodiaQ36335794
Protein complexes regulating Arp2/3-mediated actin assembly.Q36339111
A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.Q36761494
Role of actin cytoskeleton in dendritic spine morphogenesis.Q36859357
Filopodia: the fingers that do the walkingQ36915801
Actin stress fibresQ36967566
IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusionsQ37063714
Missing-in-metastasis and IRSp53 deform PI(4,5)P2-rich membranes by an inverse BAR domain-like mechanismQ39734937
Polymerizing actin fibers position integrins primed to probe for adhesion sitesQ40170442
Cdc42 and ARP2/3-independent regulation of filopodia by an integral membrane lipid-phosphatase-related proteinQ40188060
Micromechanics of filopodia mediated capture of pathogens by macrophagesQ40198042
IRSp53 is colocalised with WAVE2 at the tips of protruding lamellipodia and filopodia independently of MenaQ40649467
N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motilityQ40777112
Organization of actin networks in intact filopodiaQ41625141
Mechanism of actin network attachment to moving membranes: barbed end capture by N-WASP WH2 domainsQ41772059
Myosin VI targeting to clathrin-coated structures and dimerization is mediated by binding to Disabled-2 and PtdIns(4,5)P2.Q42155473
Three functionally distinct adhesions in filopodia: shaft adhesions control lamellar extension.Q42525821
The Rho family GTPase Rif induces filopodia through mDia2.Q42818923
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectfilopodium assemblyQ15311684
P304page(s)446-54
P577publication date2008-06-01
P1433published inNature Reviews Molecular Cell BiologyQ1573120
P1476titleFilopodia: molecular architecture and cellular functions
P478volume9

Reverse relations

cites work (P2860)
Q506571043D Electrospun scaffolds promote a cytotrophic phenotype of cultured primary astrocytes.
Q340169763D bioelectronic interface: capturing circulating tumor cells onto conducting polymer-based micro/nanorod arrays with chemical and topographical control
Q360139405-HT7R/G12 signaling regulates neuronal morphology and function in an age-dependent manner.
Q92130361A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
Q34483356A Hot-spot of In-frame Duplications Activates the Oncoprotein AKT1 in Juvenile Granulosa Cell Tumors.
Q35100804A POROELASTIC MODEL FOR CELL CRAWLING INCLUDING MECHANICAL COUPLING BETWEEN CYTOSKELETAL CONTRACTION AND ACTIN POLYMERIZATION
Q30278602A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration
Q52431031A Rac1-FMNL2 signaling module affects cell-cell contact formation independent of Cdc42 and membrane protrusions.
Q47998825A Stretchable Electrochemical Sensor for Inducing and Monitoring Cell Mechanotransduction in Real Time
Q91637779A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer
Q30570120A critical role for STIM1 in filopodial calcium entry and axon guidance
Q37622579A large scale Huntingtin protein interaction network implicates Rho GTPase signaling pathways in Huntington disease
Q51859399A mathematical analysis of physiological and morphological aspects of wound closure.
Q30415272A microfluidic-based genetic screen to identify microbial virulence factors that inhibit dendritic cell migration
Q92126192A nanostructure platform for live-cell manipulation of membrane curvature
Q64121554A novel Microproteomic Approach Using Laser Capture Microdissection to Study Cellular Protrusions
Q90638441A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function
Q42948239A novel fibroblast growth factor receptor family member promotes neuronal outgrowth and synaptic plasticity in aplysia.
Q41978648A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level
Q90482173A novel workflow for three-dimensional analysis of tumour cell migration
Q30826775A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion
Q63432022A single charge in the actin binding domain of fascin can independently tune the linear and non-linear response of an actin bundle network
Q89998617AIF1L regulates actomyosin contractility and filopodial extensions in human podocytes
Q51730379AIG1 affects in vitro and in vivo virulence in clinical isolates of Entamoeba histolytica.
Q60931327ALS-Linked SOD1 Mutants Enhance Neurite Outgrowth and Branching in Adult Motor Neurons
Q30496216Abnormal fiber end migration in Royal College of Surgeons rats during posterior subcapsular cataract formation.
Q50058773Acetyl-CoA carboxylase 1 regulates endothelial cell migration by shifting the phospholipid composition
Q46425114Acoustic detection of cell adhesion on a quartz crystal microbalance
Q41465736Actin Aggregations Mark the Sites of Neurite Initiation
Q50495381Actin Filament Structures in Migrating Cells.
Q47612448Actin assembly mechanisms at a glance.
Q48636116Actin dynamics in development of behavioral sensitization after withdrawal from long-term ethanol administration to mice
Q38692012Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function.
Q33840016Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia
Q58794107Actin-Based Cell Protrusion in a 3D Matrix
Q38981732Actin-Dependent Regulation of Borrelia burgdorferi Phagocytosis by Macrophages
Q28554809Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread
Q35609809Active biological materials
Q100395523Active particles induce large shape deformations in giant lipid vesicles
Q37244857Adapter protein SH2B1beta cross-links actin filaments and regulates actin cytoskeleton
Q46300732Aging-Impaired Filamentous Actin Polymerization Signaling Reduces Alveolar Macrophage Phagocytosis of Bacteria
Q58764766Alanine Scanning Mutagenesis of the C-Terminal Cytosolic End of Gpm6a Identifies Key Residues Essential for the Formation of Filopodia
Q56889782Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice
Q27300237Alterations of the cytoskeleton in human cells in space proved by life-cell imaging
Q28712239Altered patterns of filopodia production in CHO cells heterologously expressing zebra finch CB(1) cannabinoid receptors
Q41686644Altering the threshold of an excitable signal transduction network changes cell migratory modes
Q42693221An Integrated Stochastic Model of Matrix-Stiffness-Dependent Filopodial Dynamics
Q67413032An actin-based protrusion originating from a podosome-enriched region initiates macrophage fusion
Q34368627An invasive podosome-like structure promotes fusion pore formation during myoblast fusion.
Q38383035An updated look at actin dynamics in filopodia.
Q42189735Analysis of Snail1 function and regulation by Twist1 in palatal fusion
Q36342251Analysis of host microRNA function uncovers a role for miR-29b-2-5p in Shigella capture by filopodia.
Q50218894Analysis of microtubule growth dynamics arising from altered actin network structure and contractility in breast tumor cells
Q37278535Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice
Q38793354Anisotropic Materials for Skeletal-Muscle-Tissue Engineering.
Q92916388Anterior-enriched filopodia create the appearance of asymmetric membrane microdomains in polarizing C. elegans zygotes
Q53113764Any route for melanoblasts to colonize the skin!
Q47766718Application of Quasi-Steady-State Methods to Nonlinear Models of Intracellular Transport by Molecular Motors
Q39315431Are Filopodia Privileged Signaling Structures in Migrating Cells?
Q83232153Arp2/3 complex-driven spatial patterning of the BCR enhances immune synapse formation, BCR signaling and B cell activation
Q30009084Assembly of actin filaments and microtubules in Nwk F-BAR-induced membrane deformations
Q39620742Asymmetric cancer-cell filopodium growth induced by electric-fields in a microfluidic culture chip
Q90215330Autonomous dynamic control of DNA nanostructure self-assembly
Q52362776Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function.
Q34877636Basal membrane complex architecture is disrupted during posterior subcapsular cataract formation in Royal College of Surgeons rats
Q49016130Bcl-2 family proteins and cytoskeleton changes involved in DM-1 cytotoxic effect on melanoma cells
Q27309221Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells
Q41634261Binding of the chemokine CXCL12α to its natural extracellular matrix ligand heparan sulfate enables myoblast adhesion and facilitates cell motility
Q89673061Biodegradable magnesium alloy (WE43) in bone-fixation plate and screw
Q48042869Bioimpedimetric analysis in conjunction with growth dynamics to differentiate aggressiveness of cancer cells.
Q64057260Biological response of chemically treated surface of the ultrafine-grained Ti-6Al-7Nb alloy for biomedical applications
Q38747909Biomaterial-enabled delivery of SDF-1α at the ventral side of breast cancer cells reveals a crosstalk between cell receptors to promote the invasive phenotype.
Q57578474Biomechanical Cell Regulation by High Aspect Ratio Nanoimprinted Pillars
Q26766483Biophysical Aspects of T Lymphocyte Activation at the Immune Synapse
Q30573154Block-Cell-Printing for live single-cell printing
Q58796591Body Cavity Development Is Guided by Morphogen Transfer between Germ Layers
Q47127278Bombyx mori Silk Fibroin Scaffolds with Antheraea pernyi Silk Fibroin Micro/Nano Fibers for Promoting EA. hy926 Cell Proliferation
Q42834957Bone demineralization with citric acid enhances adhesion and spreading of preosteoblasts.
Q39773761Bovine colostrum promotes growth and migration of the human keratinocyte HaCaT cell line
Q59086555Bridges that guide and unite
Q38756767Bridging the gap: microfluidic devices for short and long distance cell-cell communication
Q27317149Building bridges toward invasion: tumor promoter treatment induces a novel protein kinase C-dependent phenotype in MCF10A mammary cell acini
Q37904227Building distinct actin filament networks in a common cytoplasm
Q34570309CD44: target for antiangiogenesis therapy
Q33745199CDC42 is required for epicardial and pro-epicardial development by mediating FGF receptor trafficking to the plasma membrane
Q36511505CRMPs colocalize and interact with cytoskeleton in hippocampal neurons
Q28566877CRP1, a protein localized in filopodia of growth cones, is involved in dendritic growth
Q35052017Cadherin-dependent filopodia control preimplantation embryo compaction
Q42563226Calcium-actin waves and oscillations of cellular membranes
Q37577453Calumenin-15 facilitates filopodia formation by promoting TGF-β superfamily cytokine GDF-15 transcription.
Q27307183Can hippocampal neurites and growth cones climb over obstacles?
Q30410494Capping protein is essential for cell migration in vivo and for filopodial morphology and dynamics
Q64082566Carbohydrate Metabolic Compensation Coupled to High Tolerance to Oxidative Stress in Ticks
Q40552415Carbohydrates-chitosan composite carrier for Vero cell culture
Q27666969Cargo recognition mechanism of myosin X revealed by the structure of its tail MyTH4-FERM tandem in complex with the DCC P3 domain
Q40106323Caveolin 1 restricts Group A Streptococcus invasion of nonphagocytic host cells
Q52648244Cdc42 controls primary mesenchyme cell morphogenesis in the sea urchin embryo.
Q27342778Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice
Q91923760Cell Integration with Electrospun PMMA Nanofibers, Microfibers, Ribbons, and Films: A Microscopy Study
Q35079381Cell cytoskeleton and tether extraction
Q27333264Cell elasticity determines macrophage function
Q27320530Cell interactions and patterned intercalations shape and link epithelial tubes in C. elegans
Q46256416Cell membrane biophysics with optical tweezers.
Q38961479Cell migration is another player of the minute virus of mice infection
Q38945572Cell proliferation and migration inside single cell arrays
Q36044363Cell structure imaging with bright and homogeneous nanometric light source
Q58566362Cellular Response to Surface Morphology: Electrospinning and Computational Modeling
Q61814951Cellular and Structural Studies of Eukaryotic Cells by Cryo-Electron Tomography
Q47856607Cellular behavior controlled by bio-inspired and geometry-tunable nanohairs
Q38896354Cellular chirality arising from the self-organization of the actin cytoskeleton.
Q26826846Cellular responses evoked by different surface characteristics of intraosseous titanium implants
Q55239975Changed Expression of Cytoskeleton Proteins During Lung Injury in a Mouse Model of Streptococcus pneumoniae Infection.
Q41147930Changes in E-cadherin rigidity sensing regulate cell adhesion
Q35872285Characterization of Lung Fibroblasts More than Two Decades after Mustard Gas Exposure
Q39046265Clinical implications of aldo-keto reductase family 1 member C3 and its relationship with lipocalin 2 in cancer of the uterine cervix.
Q30581893Cofilin cooperates with fascin to disassemble filopodial actin filaments
Q38644917Collective Migration of Lens Epithelial Cell Induced by Differential Microscale Groove Patterns.
Q29616634Collective cell migration in morphogenesis, regeneration and cancer
Q42737897Combinatorial morphogenesis of dendritic spines and filopodia by SPAR and alpha-actinin2.
Q35591702Combined effect of insulin-like growth factor-1 and CC chemokine ligand 2 on angiogenic events in endothelial cells
Q36715548Compositional mapping of the surface and interior of mammalian cells at submicrometer resolution
Q47204029Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration
Q57881846Condensation Agents Determine the Temperature-Pressure Stability of F-Actin Bundles
Q30157076Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions
Q33455812Coordination of membrane and actin cytoskeleton dynamics during filopodia protrusion
Q61124823Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells
Q39807770Cross-talk between Rac1 and Cdc42 GTPases regulates formation of filopodia required for dengue virus type-2 entry into HMEC-1 cells.
Q30651555Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish
Q47728974Cytocapsular tubes conduct cell translocation
Q34406845Cytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking
Q45398030Cytoskeletal actin dynamics are involved in pitch-dependent neurite outgrowth on bead monolayers
Q38235653Cytoskeletal and signaling mechanisms of neurite formation
Q42645650Cytoskeletal changes induced by allosteric modulators of calcium-sensing receptor in esophageal epithelial cells
Q37610679Cytoskeletal dynamics in growth-cone steering.
Q37741575Cytoskeleton reorganization of spreading cells on micro-patterned islands: a functional model.
Q85105254Cytoskeleton: filopodia self-assemble
Q48972749Cytotoxicity and migration of fibroblasts on two types of calcium sulfate dihydrate
Q38865695DAAM family members leading a novel path into formin research
Q47334271DCC/NTN1 complex mutations in patients with congenital hypogonadotropic hypogonadism impair GnRH neuron development
Q34042660DNAJB6 induces degradation of beta-catenin and causes partial reversal of mesenchymal phenotype
Q35672770Decoupling the role of stiffness from other hydroxyapatite signalling cues in periosteal derived stem cell differentiation
Q38868250Decrease of phosphorylated proto-oncogene CREB at Ser 133 site inhibits growth and metastatic activity of renal cell cancer
Q43107811Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis
Q30435838Dendritic Spines: Similarities with Protrusions and Adhesions in Migrating Cells
Q36455457Dendritic spine geometry can localize GTPase signaling in neurons
Q34742636Detection of CD133 (prominin-1) in a human hepatoblastoma cell line (HuH-6 clone 5).
Q35512401Developmental alterations of the C. elegans male anal depressor morphology and function require sex-specific cell autonomous and cell non-autonomous interactions
Q36993499Different modes of growth cone collapse in NG 108-15 cells
Q35743292Differential dynamics of platelet contact and spreading
Q41136909Differential effects of N-linked glycosylation of Vstm5 at multiple sites on surface expression and filopodia formation.
Q27331332Differential effects of tissue culture coating substrates on prostate cancer cell adherence, morphology and behavior
Q38883549Differentiation of neuroepithelial stem cells into functional dopaminergic neurons in 3D microfluidic cell culture
Q38854587Dimensionality of Rolled-up Nanomembranes Controls Neural Stem Cell Migration Mechanism
Q55514411Direct cell-to-cell transmission of respiratory viruses: The fast lanes.
Q38585751Discovery of novel drug targets and their functions using phenotypic screening of natural products
Q37447885Disruption of actin filaments and suppression of pancreatic cancer cell viability and migration following treatment with polyisoprenylated cysteinyl amides
Q33862486Dissecting regulatory networks of filopodia formation in a Drosophila growth cone model
Q27304686Distinct predictive performance of Rac1 and Cdc42 in cell migration
Q34673431Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells
Q41337842Dopamine transporter is enriched in filopodia and induces filopodia formation
Q39177124Down expression of LRP1B promotes cell migration via RhoA/Cdc42 pathway and actin cytoskeleton remodeling in renal cell cancer
Q52700093Drosophila growth cones: a genetically tractable platform for the analysis of axonal growth dynamics.
Q42504214Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision
Q24646242Dynamic length regulation of sensory stereocilia
Q26999254Dynamic reorganization of the actin cytoskeleton
Q58690893Dynamics of Spreading and Alignment of Cells Cultured In Vitro on a Grooved Polymer Surface
Q38692074Dynamics of filopodium-like protrusion and endothelial cellular motility on one-dimensional extracellular matrix fibrils.
Q37116661Dynamics of membrane nanotubes coated with I-BAR.
Q26772875Dynamics of the actin cytoskeleton mediates receptor cross talk: An emerging concept in tuning receptor signaling
Q50507092Dystroglycan promotes filopodial formation and process branching in differentiating oligodendroglia.
Q47807637ERK signalling as a regulator of cell motility
Q92893144Easy and low-cost stable positioning of suspension cells during live-cell imaging
Q39885377Effect of capping protein on a growing filopodium
Q64074350Effect of tolytoxin on tunneling nanotube formation and function
Q50142648Effects of platelet-rich plasma on biological activity and bone regeneration of brushite-based calcium phosphate cement
Q37093929Efficient Multiscale Models of Polymer Assembly
Q52312094Efficient models of polymerization applied to FtsZ ring assembly in Escherichia coli.
Q33564094Electron tomography reveals unbranched networks of actin filaments in lamellipodia
Q37062699Electrophoretic coating of amphiphilic chitosan colloids on regulating cellular behaviour
Q38152420Embryonic and larval neural connectivity: progressive changes in synapse form and function at the neuromuscular junction mediated by cytoskeletal regulation
Q28238533Emergent complexity of the cytoskeleton: from single filaments to tissue
Q64256551Emerging Roles of Autophagy and Inflammasome in Ehrlichiosis
Q57921405Emerging role of contact-mediated cell communication in tissue development and diseases
Q36926955Endocytosis and serpentine filopodia drive blebbishield-mediated resurrection of apoptotic cancer stem cells
Q27310601Endocytosis-dependent coordination of multiple actin regulators is required for wound healing
Q30755062Endoplasmic Reticulum-resident Heat Shock Protein 90 (HSP90) Isoform Glucose-regulated Protein 94 (GRP94) Regulates Cell Polarity and Cancer Cell Migration by Affecting Intracellular Transport
Q27005949Endothelial cell-cell adhesion during zebrafish vascular development
Q30407601Endothelial cells use dynamic actin to facilitate lymphocyte transendothelial migration and maintain the monolayer barrier.
Q26865091Endothelial tip cells in ocular angiogenesis: potential target for anti-angiogenesis therapy
Q38267211Engineering the cell-semiconductor interface: a materials modification approach using II-VI and III-V semiconductor materials
Q90304371Engraving the Surface of Electrospun Microfibers with Nanoscale Grooves Promotes the Outgrowth of Neurites and the Migration of Schwann Cells
Q43223403Epigenetic regulation of miR-17~92 contributes to the pathogenesis of pulmonary fibrosis
Q26801442Epithelia migration: a spatiotemporal interplay between contraction and adhesion
Q34561559Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation
Q48339195Epithelial-mesenchymal transition, and collective and individual cell migration regulate epithelial changes in the amikacin-damaged organ of Corti
Q24336902Evidence for the involvement of FAM110C protein in cell spreading and migration
Q37146947Exo70 generates membrane curvature for morphogenesis and cell migration
Q30826764Exosomes surf on filopodia to enter cells at endocytic hot spots, traffic within endosomes, and are targeted to the ER
Q30492321Exploring the roles of diaphanous and enabled activity in shaping the balance between filopodia and lamellipodia.
Q38715397Extended Low-Dose Exposure to Saxitoxin Inhibits Neurite Outgrowth in Model Neuronal Cells.
Q30620668F-actin bundles direct the initiation and orientation of lamellipodia through adhesion-based signaling
Q35047213Fabrication of Density Gradients of Biodegradable Polymer Microparticles and Their Use in Guiding Neurite Outgrowth
Q38750488Fascin Regulates Nuclear Movement and Deformation in Migrating Cells
Q30755124Fascin Rigidity and L-plastin Flexibility Cooperate in Cancer Cell Invadopodia and Filopodia
Q51115861Fascin phosphorylation sites combine to regulate esophageal squamous cancer cell behavior.
Q35962314Fascin promotes filopodia formation independent of its role in actin bundling
Q61446728Fascin-1 enhances experimental osteosarcoma tumor formation and metastasis and is related to poor patient outcome
Q27311545Fascin1-dependent Filopodia are required for directional migration of a subset of neural crest cells
Q38725594Fascin2 regulates cisplatin-induced apoptosis in NRK-52E cells
Q27323167Fast, label-free super-resolution live-cell imaging using rotating coherent scattering (ROCS) microscopy
Q37701605Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma
Q34860614FiloDetect: automatic detection of filopodia from fluorescence microscopy images
Q38648007FiloQuant reveals increased filopodia density during breast cancer progression.
Q26751070Filopodia and Viruses: An Analysis of Membrane Processes in Entry Mechanisms
Q26823315Filopodia and adhesion in cancer cell motility
Q41976915Filopodia formation and endosome clustering induced by mutant plus-end-directed myosin VI.
Q41601984Filopodia formation by crosslinking of F-actin with fascin in two different binding manners.
Q26799486Filopodia in cell adhesion, 3D migration and cancer cell invasion
Q37942763Filopodia initiation: focus on the Arp2/3 complex and formins
Q93257727Filopodia play an important role in the trans-mesothelial migration of ovarian cancer cells
Q42735921Filopodial focal complexes direct adhesion and force generation towards filopodia outgrowth
Q37340926Filopodial retraction force is generated by cortical actin dynamics and controlled by reversible tethering at the tip.
Q42282913Filopodyan: An open-source pipeline for the analysis of filopodia.
Q38808531Flexible Gold Nanocone Array Surfaces as a Tool for Regulating Neuronal Behavior.
Q27332299Fluxes of water through aquaporin 9 weaken membrane-cytoskeleton anchorage and promote formation of membrane protrusions
Q97643164Force-exerting perpendicular lateral protrusions in fibroblastic cell contraction
Q39909551Formin proteins of the DAAM subfamily play a role during axon growth.
Q58133816Fractal analysis of cell boundary ultrastructure imaged by atomic force microscopy
Q34891185Free edges in epithelia as cues for motility
Q37958909From filopodia to synapses: the role of actin-capping and anti-capping proteins.
Q39619632Functional and biochemical studies of CD9 in fibrosarcoma cell line
Q33787522Functional roles of VASP phosphorylation in the regulation of chemotaxis and osmotic stress response
Q30898776Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPARgamma signaling as potential mechanism for the negative relationships between immune [...]
Q41806867Generation of neuromuscular specificity in Drosophila: novel mechanisms revealed by new technologies
Q51067426Generic Transport Mechanisms for Molecular Traffic in Cellular Protrusions.
Q27319264Geometrical and mechanical properties control actin filament organization
Q39069327Glucose deprivation increases monocarboxylate transporter 1 (MCT1) expression and MCT1-dependent tumor cell migration
Q36175385Glycolytic inhibitor 2-deoxyglucose simultaneously targets cancer and endothelial cells to suppress neuroblastoma growth in mice
Q38040667Going against the tide--how encephalitogenic T cells breach the blood-brain barrier
Q27300770Growth arrest specific gene 7 is associated with schizophrenia and regulates neuronal migration and morphogenesis
Q38187040Growth factors and early mesoderm morphogenesis: insights from the sea urchin embryo
Q51517448Guidance signalling regulates leading edge behaviour during collective cell migration of cardiac cells in Drosophila.
Q99711288HAuCl4, Putative General Aquaporins Blocker, Reduces Platelet Spreading, Filopodia Formation, Procoagulant Response, and Thrombus Formation Under Flow
Q33737282HGF/Met Signaling in Cancer Invasion: The Impact on Cytoskeleton Remodeling
Q30841147Harnessing molecular motors for nanoscale pulldown in live cells.
Q36127036Headless Myo10 is a negative regulator of full-length Myo10 and inhibits axon outgrowth in cortical neurons
Q64950307Health hazards of methylammonium lead iodide based perovskites: cytotoxicity studies.
Q34925957Helical buckling of actin inside filopodia generates traction
Q38838091Hierarchical Micro/Nanofibrous Bioscaffolds for Structural Tissue Regeneration
Q30484408High-speed high-resolution imaging of intercellular immune synapses using optical tweezers
Q38130179How filopodia pull: what we know about the mechanics and dynamics of filopodia.
Q35121121Hsp90 C-terminal inhibitors exhibit antimigratory activity by disrupting the Hsp90α/Aha1 complex in PC3-MM2 cells
Q38870297Human aortic endothelial cell morphology influenced by topography of porous silicon substrates.
Q45857035Human bone-lineage cell responses to anisotropic Ti6Al4V surfaces are dependent on their maturation state.
Q39759111Human hepatoma cells transmit surface bound HIV-1 to CD4+ T cells through an ICAM-1/LFA-1-dependent mechanism
Q35589009Human mesenchymal stem cell behavior on femtosecond laser-textured Ti-6Al-4V surfaces.
Q42800641Human myosin VIIa is a very slow processive motor protein on various cellular actin structures
Q92502754IRSp53 coordinates AMPK and 14-3-3 signaling to regulate filopodia dynamics and directed cell migration
Q27321489IRSp53 senses negative membrane curvature and phase separates along membrane tubules
Q50017291Identifying the dynamics of actin and tubulin polymerization in iPSCs and in iPSC-derived neurons.
Q33962349Illuminating epidermal growth factor receptor densities on filopodia through plasmon coupling
Q38707944ImageJ macros for the user-friendly analysis of soft-agar and wound-healing assays
Q30580519Imaging the alphavirus exit pathway
Q37650286Immune pathology associated with altered actin cytoskeleton regulation
Q33409294Impact of actin rearrangement and degranulation on the membrane structure of primary mast cells: a combined atomic force and laser scanning confocal microscopy investigation
Q44636695Impact of polyelectrolytes and their corresponding multilayers to human primary endothelial cells
Q39569603Implication of human nonmetastatic clone 23 Type 1 and its downstream gene lipocalin 2 in metastasis and patient's survival of cancer of uterine cervix
Q39856342Improving fascin inhibitors to block tumor cell migration and metastasis
Q35826043In Vitro Mutational Analysis of the β2 Adrenergic Receptor, an In Vivo Surrogate Odorant Receptor
Q50508458In vitro angiogenesis assay for the study of cell-encapsulation therapy.
Q33764042In vivo assembly of an archaeal virus studied with whole-cell electron cryotomography
Q47554062In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis.
Q30492792In vivo nano-imaging of membrane dynamics in metastatic tumor cells using quantum dots
Q30458216In vivo reversible regulation of dendritic patterning by afferent input in bipolar auditory neurons
Q39345984In vivo subcellular localization of Mal de Río Cuarto virus (MRCV) non-structural proteins in insect cells reveals their putative functions.
Q41575115Incorporation of Collagen in Calcium Phosphate Cements for Controlling Osseointegration.
Q55260609Infection and Transport of Herpes Simplex Virus Type 1 in Neurons: Role of the Cytoskeleton.
Q39147388Influence of PECAM-1 ligand interactions on PECAM-1-dependent cell motility and filopodia extension
Q37470888Inhibition of LINE-1 retrotransposon-encoded reverse transcriptase modulates the expression of cell differentiation genes in breast cancer cells.
Q42091689Initial stem cell adhesion on porous silicon surface: molecular architecture of actin cytoskeleton and filopodial growth.
Q28238397Initial steps of metastasis: cell invasion and endothelial transmigration
Q26801604Innate Immunity and Biomaterials at the Nexus: Friends or Foes
Q37397313Insights into a novel nuclear function for Fascin in the regulation of the amino-acid transporter SLC3A2.
Q37107569Insights into the origin of metazoan filopodia and microvilli
Q60927515Insulin-like Growth Factor-1 Receptor Dictates Beneficial Effects of Treadmill Training by Regulating Survival and Migration of Neural Stem Cell Grafts in the Injured Spinal Cord
Q39030513Integrated proteomic and metabolomic analysis to assess the effects of pure and benzo[a]pyrene-loaded carbon black particles on energy metabolism and motility in the human endothelial cell line EA.hy926.
Q30541383Integrating DNA strand-displacement circuitry with DNA tile self-assembly
Q48171891Integrating transient cellular and nuclear motions to comprehensively describe cell migration patterns.
Q30437361Integrins in cell migration--the actin connection
Q30532774Interaction between p68 RNA helicase and Ca2+-calmodulin promotes cell migration and metastasis
Q39391085Interactions of Neurons with Physical Environments
Q37694410Intercellular nanotubes: insights from imaging studies and beyond
Q63987397Interferometric scattering microscopy reveals microsecond nanoscopic protein motion on a live cell membrane
Q38114023Intrinsic structural disorder in cytoskeletal proteins.
Q28383759Introduction to cell-hydrogel mechanosensing
Q39332459Invadosomes are coming: new insights into function and disease relevance
Q37050915Inversin modulates the cortical actin network during mitosis
Q27342988Investigating biomechanical noise in neuroblastoma cells using the quartz crystal microbalance
Q38220858Involvement of Rho-family GTPases in axon branching
Q37339182Involvement of headless myosin X in the motility of immortalized gonadotropin-releasing hormone neuronal cells
Q47341713In vitro developmental acceleration of hippocampal neurons on nanostructures of self-assembled silica beads in filopodium-size ranges
Q34650681Islands of conformational stability for filopodia
Q39209401It takes a village to raise a branch: Cellular mechanisms of the initiation of axon collateral branches
Q38834432LIM domain only 2 induces glioma invasion via cytosolic p27(KIP1).
Q42615890LIN7-IRSp53: A novel pathway for filopodia and neurite formation?
Q38109449Learning and memory: an emergent property of cell motility
Q37098075Linked in: immunologic membrane nanotube networks
Q46367877Linking actin networks and cell membrane via a reaction-diffusion-elastic description of nonlinear filopodia initiation
Q46252318Liposomal internal viscosity affects the fate of membrane deformation induced by hypertonic treatment
Q53031302Live endothelial cells imaged by Scanning Near-field Optical Microscopy (SNOM): capabilities and challenges.
Q53176393LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis.
Q27350086Local ATP generation by brain-type creatine kinase (CK-B) facilitates cell motility
Q28566730Localization of myosin 1b to actin protrusions requires phosphoinositide binding
Q30418602Long-distance relationships: do membrane nanotubes regulate cell-cell communication and disease progression?
Q37798031Lung epithelial wound healing in health and disease
Q39771216M-Sec promotes membrane nanotube formation by interacting with Ral and the exocyst complex
Q38824234MARVELD1 modulates cell surface morphology and suppresses epithelial-mesenchymal transition in non-small cell lung cancer
Q38017588MDM2 binding protein, a novel metastasis suppressor
Q36214196MIEN1 promotes oral cancer progression and implicates poor overall survival
Q91832231MT1-MMP-dependent cell migration: proteolytic and non-proteolytic mechanisms
Q37092231MTBP suppresses cell migration and filopodia formation by inhibiting ACTN4
Q42153572Macrophages engulf endothelial cell membrane particles preceding pupillary membrane capillary regression
Q91938172Mammalian germ cell migration during development, growth, and homeostasis
Q89031372Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling
Q38816287Marek's disease virus undergoes complete morphogenesis after reactivation in a T-lymphoblastoid cell line transformed by recombinant fluorescent marker virus.
Q52666822Marine Bacterial Polysaccharide EPS11 Inhibits Cancer Cell Growth via Blocking Cell Adhesion and Stimulating Anoikis.
Q39108934Materials learning from life: concepts for active, adaptive and autonomous molecular systems
Q27348613Maturation of filopodia shaft adhesions is upregulated by local cycles of lamellipodia advancements and retractions
Q30530546Measuring forces at the leading edge: a force assay for cell motility
Q28569052Mechanisms controlling neurite outgrowth in a pheochromocytoma cell line: the role of TRPC channels
Q54260276Mechanisms for Cell-to-Cell Transmission of HIV-1.
Q55265662Mechanisms of Aquaporin-Facilitated Cancer Invasion and Metastasis.
Q42995365Mechanisms of cellular protrusions branch out.
Q38219575Mechanosensing of cells in 3D gel matrices based on natural and synthetic materials
Q38830966Membrane curvature in cell biology: An integration of molecular mechanisms
Q38798552Membrane curvature regulates ligand-specific membrane sorting of GPCRs in living cells.
Q112697334Membrane curvature regulates the spatial distribution of bulky glycoproteins
Q37902570Membrane shaping by the Bin/amphiphysin/Rvs (BAR) domain protein superfamily
Q47576945Merkel Cell Polyomavirus Small T Antigen Drives Cell Motility via Rho-GTPase-Induced Filopodium Formation
Q30494801Mesoderm migration in Drosophila is a multi-step process requiring FGF signaling and integrin activity.
Q39654247Metabolomic Identification of the Target of the Filopodia Protrusion Inhibitor Glucopiericidin A
Q35040904Metastasis suppressor microRNA-335 targets the formin family of actin nucleators
Q36191451Metastatic bladder cancer cells distinctively sense and respond to physical cues of collagen fibril-mimetic nanotopography
Q36855499Metformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In Vivo
Q83976192MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells
Q36590531Microfabricated Systems and Assays for Studying the Cytoskeletal Organization, Micromechanics, and Motility Patterns of Cancerous Cells
Q94024060Microridges are apical epithelial projections formed of F-actin networks that organize the glycan layer
Q42842098Microtubule-Actin Crosslinking Factor 1 Is Required for Dendritic Arborization and Axon Outgrowth in the Developing Brain
Q28534220Migrastatin analogues inhibit canine mammary cancer cell migration and invasion
Q28602690Migration of Founder Epithelial Cells Drives Proper Molar Tooth Positioning and Morphogenesis
Q46553390Mimicking native extracellular matrix with phytic acid-crosslinked protein nanofibers for cardiac tissue engineering
Q38839147Minireview: Role of genetic changes of faciogenital dysplasia protein 1 in human disease
Q37625339Mitochondrial Dynamics in Retinal Ganglion Cell Axon Regeneration and Growth Cone Guidance
Q30828377Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
Q28075887Modulating Astrocyte Transition after Stroke to Promote Brain Rescue and Functional Recovery: Emerging Targets Include Rho Kinase
Q42497527Modulation of growth cone filopodial length by carbon monoxide
Q53296434Modulators of endothelial cell filopodia: PECAM-1 joins the club.
Q36789861Molar concentration from sequential 2-D water-window X-ray ptychography and X-ray fluorescence in hydrated cells
Q27675250Molecular Mechanism of Fascin Function in Filopodial Formation
Q30436753Molecular architecture of synaptic actin cytoskeleton in hippocampal neurons reveals a mechanism of dendritic spine morphogenesis
Q90836048Morphological changes in synovial mesenchymal stem cells during their adhesion to the meniscus
Q34594974Morphological development of thick-tufted layer v pyramidal cells in the rat somatosensory cortex
Q28383381Moscatilin inhibits lung cancer cell motility and invasion via suppression of endogenous reactive oxygen species
Q39830440Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth
Q42235661Multi-resolution 3D visualization of the early stages of cellular uptake of peptide-coated nanoparticles.
Q38736162Multiple Roles of the Cytoplasmic Domain of Herpes Simplex Virus 1 Envelope Glycoprotein D in Infected Cells
Q48623666Multiple roles of filopodial dynamics in particle capture and phagocytosis and phenotypes of Cdc42 and Myo10 deletion
Q33956060Munc18 and Munc13 regulate early neurite outgrowth
Q30572690Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis.
Q55056709Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment.
Q37515120MyTH4-FERM myosins have an ancient and conserved role in filopod formation
Q52689190Myosin 10 is involved in murine pigmentation.
Q92534304Myosin IIA and formin dependent mechanosensitivity of filopodia adhesion
Q42652879Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation
Q89545561Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis
Q34985570Myosin motor function: the ins and outs of actin-based membrane protrusions.
Q64229861Myosin-X Silencing in the Trabecular Meshwork Suggests a Role for Tunneling Nanotubes in Outflow Regulation
Q26825835Myosin-X and disease
Q30576361Myosin-X is critical for migratory ability of Xenopus cranial neural crest cells.
Q35576442Myosin-X: a MyTH-FERM myosin at the tips of filopodia
Q90334412Myxozoan Adhesion and Virulence: Ceratonova shasta on the Move
Q28571875N-WASP and cortactin are involved in invadopodium-dependent chemotaxis to EGF in breast tumor cells
Q39105321NF-κB-mediated transcriptional upregulation of TNFAIP2 by the Epstein-Barr virus oncoprotein, LMP1, promotes cell motility in nasopharyngeal carcinoma.
Q40036220NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells.
Q39909755Nanoporous metals for biodegradable implants: Initial bone mesenchymal stem cell adhesion and degradation behavior
Q33697370Nanostructures of designed geometry and functionality enable regulation of cellular signaling processes
Q47241232Nanotechnology, nanosurfaces and silicone gel breast implants: current aspects
Q64448228Nanowired Bioelectric Interfaces
Q50420864Neurexin and Neuroligin-based adhesion complexes drive axonal arborisation growth independent of synaptic activity.
Q37731661Neurite outgrowth on electrospun nanofibers with uniaxial alignment: the effects of fiber density, surface coating, and supporting substrate
Q37395803Neurite outgrowth on nanofiber scaffolds with different orders, structures, and surface properties
Q60950991Neuronal Migration During Development of the Cerebellum
Q48949901Neuronal filopodium formation induced by the membrane glycoprotein M6a (Gpm6a) is facilitated by coronin-1a, Rac1, and p21-activated kinase 1 (Pak1).
Q38309247Neuropathologic characterization of INF2-related Charcot-Marie-Tooth disease: evidence for a Schwann cell actinopathy.
Q37855886New approaches to targeting the actin cytoskeleton for chemotherapy
Q52364597New insights into the formation and the function of lamellipodia and ruffles in mesenchymal cell migration.
Q34070345Ninjurin1 enhances the basal motility and transendothelial migration of immune cells by inducing protrusive membrane dynamics.
Q35913612Nitric Oxide Chemical Donor Affects the Early Phases of In Vitro Wound Healing Process.
Q64274109Non-Viral Delivery System and Targeted Bone Disease Therapy
Q39881118Nonkinase activity of MLCK in elongated filopodia formation and chemotaxis of vascular smooth muscle cells toward sphingosylphosphorylcholine
Q48189185Notch signalling restricts inflammation and serpine1 expression in the dynamic endocardium of the regenerating zebrafish heart
Q57132020Novel Titania Nanocoatings Produced by Anodic Oxidation with the Use of Cyclically Changing Potential: Their Photocatalytic Activity and Biocompatibility
Q41429724On the mechanical stabilization of filopodia
Q42600795One isoform of Arg/Abl2 tyrosine kinase is nuclear and the other seven cytosolic isoforms differently modulate cell morphology, motility and the cytoskeleton
Q30638871Open source software for quantification of cell migration, protrusions, and fluorescence intensities
Q89748346Optogenetic control of mRNA localization and translation in live cells
Q28385469Ouabain suppresses the migratory behavior of lung cancer cells
Q27309036PCP Signaling between Migrating Neurons and their Planar-Polarized Neuroepithelial Environment Controls Filopodial Dynamics and Directional Migration
Q33812808Patterning of novel breast implant surfaces by enhancing silicone biocompatibility, using biomimetic topographies
Q89430427Paxillin phosphorylation at serine 273 and its effects on Rac, Rho and adhesion dynamics
Q38716094Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.
Q91651821Perspectives of cellular communication through tunneling nanotubes in cancer cells and the connection to radiation effects
Q55322531Perspectives on Intra- and Intercellular Trafficking of Hedgehog for Tissue Patterning.
Q47560517Phenomenological modeling of durotaxis
Q42290733Phosphatidylethanolamine dynamics are required for osteoclast fusion
Q48348422Phosphatidylinositol 3,4-bisphosphate regulates neurite initiation and dendrite morphogenesis via actin aggregation
Q42102400Physical model for the geometry of actin-based cellular protrusions.
Q37423545Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury.
Q28505932Plasticity-related gene 5 (PRG5) induces filopodia and neurite growth and impedes lysophosphatidic acid- and nogo-A-mediated axonal retraction
Q38712994Plectin deficiency in liver cancer cells promotes cell migration and sensitivity to sorafenib treatment
Q33605918Polarity proteins and cell-cell interactions in the testis
Q38871489Polo-like kinase 2 regulates angiogenic sprouting and blood vessel development
Q24305028Prenylated c17orf37 induces filopodia formation to promote cell migration and metastasis
Q92189011Profilin 1 Negatively Regulates Osteoclast Migration in Postnatal Skeletal Growth, Remodeling, and Homeostasis in Mice
Q58088565Profilin 1 binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation
Q39146349Programmable fractal nanostructured interfaces for specific recognition and electrochemical release of cancer cells
Q100558732Proline-rich transmembrane protein 2 (PRRT2) regulates the actin cytoskeleton during synaptogenesis
Q24338447Prominin-2 expression increases protrusions, decreases caveolae and inhibits Cdc42 dependent fluid phase endocytosis
Q27347818Propagating cell-membrane waves driven by curved activators of actin polymerization
Q55154045Proteomic comparison of the EWS-FLI1 expressing cells EF with NIH-3T3 and actin remodeling effect of (R/W)9 cell-penetrating peptide.
Q51861945Proteomics profiling of human embryonic stem cells in the early differentiation stage.
Q47035977Putative Cell Adhesion Membrane Protein Vstm5 Regulates Neuronal Morphology and Migration in the Central Nervous System.
Q40426575Quantification of Type, Timing, and Extent of Cell Body and Nucleus Deformations Caused by the Dimensions and Hydrophilicity of Square Prism Micropillars
Q28265491R-Ketorolac Targets Cdc42 and Rac1 and Alters Ovarian Cancer Cell Behaviors Critical for Invasion and Metastasis
Q38727367RB Loss Promotes Prostate Cancer Metastasis
Q98945155RET isoforms contribute differentially to invasive processes in pancreatic ductal adenocarcinoma
Q41047666ROS induced distribution of mitochondria to filopodia by Myo19 depends on a class specific tryptophan in the motor domain.
Q47326932RalGPS2 is involved in tunneling nanotubes formation in 5637 bladder cancer cells
Q57351720Rapid osteogenic differentiation of mesenchymal stem cells on hydroxyapatite nanocrystal clusters-oriented nanotopography
Q36072510Real-Time Biological Annotation of Synthetic Compounds.
Q37735359Rear actomyosin contractility-driven directional cell migration in three-dimensional matrices: a mechano-chemical coupling mechanism
Q37571307Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development
Q33990332Reflectivity and topography of cells grown on glass-coverslips measured with phase-shifted laser feedback interference microscopy
Q36557397Regulation and functional significance of CDC42 alternative splicing in ovarian cancer
Q37542009Regulation of actin cytoskeleton dynamics in cells
Q36853200Regulation of invadopodia by mechanical signaling
Q39432011Regulation of long-distance transport of mitochondria along microtubules
Q36209884Regulation of membrane-shape transitions induced by I-BAR domains
Q37677924Regulation of the actin cytoskeleton-plasma membrane interplay by phosphoinositides
Q41991920Remodeling of dendrites and spines in the C1q knockout model of genetic epilepsy
Q28395128Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells
Q42368536Repulsive Guidance Molecule a Inhibits Angiogenesis by Downregulating VEGF and Phosphorylated Focal Adhesion Kinase In Vitro
Q36291078Resolution doubling in live, multicellular organisms via multifocal structured illumination microscopy.
Q53298646Response of filopodia and lamellipodia to surface topography on micropatterned silk fibroin films.
Q41354217Retinoblastoma protein (Rb) links hypoxia to altered mechanical properties in cancer cells as measured by an optical tweezer
Q37431430Retracted: Macrophages Mediate a Switch between Canonical and Non-Canonical Wnt Pathways in Canine Mammary Tumors
Q30484304Retrograde flow and myosin II activity within the leading cell edge deliver F-actin to the lamella to seed the formation of graded polarity actomyosin II filament bundles in migrating fibroblasts
Q30528815RhoD activated by fibroblast growth factor induces cytoneme-like cellular protrusions through mDia3C.
Q39588446Rif-mDia1 interaction is involved in filopodium formation independent of Cdc42 and Rac effectors
Q38858414Role of Moesin in Advanced Glycation End Products-Induced Angiogenesis of Human Umbilical Vein Endothelial Cells
Q35959721Role of the cofilin activity cycle in astrocytoma migration and invasion
Q42462846S-nitrosylation of Cofilin-1 Serves as a Novel Pathway for VEGF-Stimulated Endothelial Cell Migration
Q37571115SDF-1/CXCR4 axis induces human dental pulp stem cell migration through FAK/PI3K/Akt and GSK3β/β-catenin pathways
Q49900699SGEF is a potential prognostic and therapeutic target for lung adenocarcinoma.
Q34211722SHP-2 phosphatase activity is required for PECAM-1-dependent cell motility
Q101226427SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts
Q38875325SOCS3 induces neurite differentiation and promotes neuronal cell survival
Q38782022Scinderin promotes the invasion and metastasis of gastric cancer cells and predicts the outcome of patients
Q83164082Seeding density matters: extensive intercellular contact masks the surface dependence of endothelial cell-biomaterial interactions
Q90012532Selective Regulation of Cytoskeletal Dynamics and Filopodia Formation by Teleost Leukocyte Immune-Type Receptors Differentially Contributes to Target Capture During the Phagocytic Process
Q30663513Self-organization of waves and pulse trains by molecular motors in cellular protrusions
Q38999658Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons.
Q36748169Shielding of the Geomagnetic Field Alters Actin Assembly and Inhibits Cell Motility in Human Neuroblastoma Cells
Q30977698Signaling involved in neurite outgrowth of postnatally born subventricular zone neurons in vitro
Q40498880Signalling Pathways Controlling Cellular Actin Organization
Q41681034Silver nanoparticles do not alter human osteoclastogenesis but induce cellular uptake
Q38751024Simiate is an Actin binding protein involved in filopodia dynamics and arborization of neurons
Q41971417Simulated microgravity triggers epithelial mesenchymal transition in human keratinocytes
Q36319424Single Cell Transcriptomics, Mega-Phylogeny, and the Genetic Basis of Morphological Innovations in Rhizaria
Q30541727Single quantum dot tracking reveals that an individual multivalent HIV-1 Tat protein transduction domain can activate machinery for lateral transport and endocytosis
Q43102537Skelemin in integrin α(IIb)β(3) mediated cell spreading
Q55386096Small Rho GTPases and the Effector VipA Mediate the Invasion of Epithelial Cells by Filamentous Legionella pneumophila.
Q42976628Sodium channel β2 subunit promotes filopodia-like processes and expansion of the dendritic tree in developing rat hippocampal neurons
Q34110627Soluble THSD7A is an N-glycoprotein that promotes endothelial cell migration and tube formation in angiogenesis
Q92474355Spatiotemporal characterization of dynamic epithelial filopodia during zebrafish epiboly
Q24302055Sphingosine 1-phosphate induces filopodia formation through S1PR2 activation of ERM proteins
Q40424244Spiral ganglion stem cells can be propagated and differentiated into neurons and glia
Q27329412Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
Q37081374Steric Effects Induce Geometric Remodeling of Actin Bundles in Filopodia
Q42101377Steric Pressure among Membrane-Bound Polymers Opposes Lipid Phase Separation
Q52343408Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor.
Q33639654Structural and mechanical functions of integrins
Q27674679Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensor
Q37612047Substrate Stiffness Influences Doxorubicin-Induced p53 Activation via ROCK2 Expression.
Q57171393Sulfonic groups induce formation of filopodia in mesenchymal stem cells
Q30655968Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration
Q98771671T Cell Membrane Heterogeneity Aids Antigen Recognition and T Cell Activation
Q26774663T Lymphocyte Migration: An Action Movie Starring the Actin and Associated Actors.
Q53292614T cells sense biophysical cues using lamellipodia and filopodia to optimize intraluminal path finding.
Q35819455TM4SF1: a tetraspanin-like protein necessary for nanopodia formation and endothelial cell migration
Q53206620Targeted inhibition of fascin function blocks tumour invasion and metastatic colonization.
Q36392283Targeted massive parallel sequencing: the effective detection of novel causative mutations associated with hearing loss in small families
Q47984457Targeting cancer cell integrins using gold nanorods in photothermal therapy inhibits migration through affecting cytoskeletal proteins
Q48608544Targeting de novo lipogenesis as a novel approach in anti-cancer therapy
Q33905523Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter
Q37594001Teneurin-4 promotes cellular protrusion formation and neurite outgrowth through focal adhesion kinase signaling
Q37997323Tetraspanins and cell membrane tubular structures
Q24614572The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function
Q47236946The Actin Cytoskeleton and Actin-Based Motility
Q92059149The Biological Evaluation of Conventional and Nano-Hydroxyapatite-Silica Glass Ionomer Cement on Dental Pulp Stem Cells: A Comparative Study
Q50577426The Drosophila histone demethylase dKDM5/LID regulates hematopoietic development.
Q34777387The Dynamics of Morphogenesis in the Early Mouse Embryo.
Q60938983The Effect of Scaffold Modulus on the Morphology and Remodeling of Fetal Mesenchymal Stem Cells
Q36055837The Effects of TiO2 Nanodot Films with RGD Immobilization on Light-Induced Cell Sheet Technology
Q33981225The Eps8/IRSp53/VASP network differentially controls actin capping and bundling in filopodia formation
Q24654793The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis
Q28548287The Frog Skin-Derived Antimicrobial Peptide Esculentin-1a(1-21)NH2 Promotes the Migration of Human HaCaT Keratinocytes in an EGF Receptor-Dependent Manner: A Novel Promoter of Human Skin Wound Healing?
Q39463765The H1047R point mutation in p110 alpha changes the morphology of human colon HCT116 cancer cells
Q27316085The More the Tubular: Dynamic Bundling of Actin Filaments for Membrane Tube Formation
Q40649402The N-terminal acetyltransferase Naa10 is essential for zebrafish development
Q24308702The RNA binding protein Larp1 regulates cell division, apoptosis and cell migration
Q39042781The Rho GTPase Rac1 is required for recycling endosome-mediated secretion of TNF in macrophages
Q35005676The Rho kinase inhibitor Fasudil up-regulates astrocytic glutamate transport subsequent to actin remodelling in murine cultured astrocytes
Q55438744The Role of the Microtubule Cytoskeleton in Neurodevelopmental Disorders.
Q41636614The Roles of Hypoxia Signaling in the Pathogenesis of Cardiovascular Diseases
Q38716143The Therapeutic Potential of Migrastatin-Core Analogs for the Treatment of Metastatic Cancer.
Q30157367The Toca-1-N-WASP complex links filopodial formation to endocytosis
Q30503395The actin nucleating Arp2/3 complex contributes to the formation of axonal filopodia and branches through the regulation of actin patch precursors to filopodia
Q35964611The biological role of actinin-4 (ACTN4) in malignant phenotypes of cancer
Q24289355The cell surface environment for pathogen recognition and entry
Q92402756The chaperone ERp29 is required for tunneling nanotube formation by stabilizing MSec
Q28305090The cytoskeletal and signaling mechanisms of axon collateral branching
Q35672305The cytoskeletal mechanisms of cell-cell junction formation in endothelial cells
Q27687036The cytoskeleton and neurite initiation
Q47191292The effect of ordered and partially ordered surface topography on bone cell responses: a review.
Q51116309The effects of nanotopography and coculture systems to promote angiogenesis for wound repair.
Q39126569The formin Daam1 and fascin directly collaborate to promote filopodia formation.
Q30539638The formins FMNL1 and mDia1 regulate coiling phagocytosis of Borrelia burgdorferi by primary human macrophages
Q58092132The modulation effect of the convexity of silicon topological nanostructures on the growth of mesenchymal stem cells
Q83230604The molecular architecture of engulfment during sporulation
Q30493646The motor protein myosin-X transports VE-cadherin along filopodia to allow the formation of early endothelial cell-cell contacts.
Q36162084The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions
Q30156886The proposed functions of membrane curvatures mediated by the BAR domain superfamily proteins
Q35556999The role of actin bundling proteins in the assembly of filopodia in epithelial cells
Q92589647The role of actin protrusion dynamics in cell migration through a degradable viscoelastic extracellular matrix: Insights from a computational model
Q30538842The role of filopodia in the recognition of nanotopographies
Q90466747The role of traction in membrane curvature generation
Q90250144The role of urea in neuronal degeneration and sensitization: An in vitro model of uremic neuropathy
Q37880684The roles of fascins in health and disease
Q38717553The sense is in the fingertips: The distal end controls filopodial mechanics and dynamics in response to external stimuli
Q48675311The small GTPase Cdc42 promotes membrane protrusion during polar body emission via ARP2-nucleated actin polymerization
Q39203499The temporal basis of angiogenesis
Q39699837The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells
Q39433431The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1.
Q34976234The trip of the tip: understanding the growth cone machinery.
Q41498724The use of a genetically encoded molecular crowding sensor in various biological phenomena.
Q27333926Theoretical model for cellular shapes driven by protrusive and adhesive forces
Q28067186There Is No Simple Model of the Plasma Membrane Organization
Q47162939Thermodynamics and kinetics of DNA nanotube polymerization from single-filament measurements
Q36606008Three-Dimensional Characterization of Mechanical Interactions between Endothelial Cells and Extracellular Matrix during Angiogenic Sprouting
Q27335266Topographic Cues Reveal Two Distinct Spreading Mechanisms in Blood Platelets
Q38953599Topographic cell instructive patterns to control cell adhesion, polarization and migration
Q53476706Traction stress analysis and modeling reveal that amoeboid migration in confined spaces is accompanied by expansive forces and requires the structural integrity of the membrane-cortex interactions.
Q35103816Transcriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis.
Q38502206Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor fasudil reveals cytoskeletal and pro-survival responses
Q48160287Transformation of the Non-Selective Aminocyclohexanol-Based Hsp90 Inhibitor into a Grp94-Seletive Scaffold
Q35347566Triclosan potentiates epithelial-to-mesenchymal transition in anoikis-resistant human lung cancer cells
Q39403862Tumor angiogenesis and vascular normalization: alternative therapeutic targets
Q58058770Tuning neuron adhesion and neurite guiding using functionalized AuNPs and backfill chemistry
Q42631366Tunneling Nanotubes are Novel Cellular Structures That Communicate Signals Between Trabecular Meshwork Cells
Q38207996Tunneling nanotubes: Diversity in morphology and structure
Q42374860Turnover and flow of the cell membrane for cell migration.
Q38671718Tweety-Homolog 1 Drives Brain Colonization of Gliomas.
Q27438067Two distinct filopodia populations at the growth cone allow to sense nanotopographical extracellular matrix cues to guide neurite outgrowth
Q38954442Tyrosine 251 at the C-terminus of neuronal glycoprotein M6a is critical for neurite outgrowth
Q41942195Ultrastructure of microglia-synapse interactions in the HIV-1 Tat-injected murine central nervous system
Q42356432Unconventional Transport Routes of Soluble and Membrane Proteins and Their Role in Developmental Biology.
Q89738073Unidirectional rotating molecular motors dynamically interact with adsorbed proteins to direct the fate of mesenchymal stem cells
Q99609981Unique cellular protrusions mediate breast cancer cell migration by tethering to osteogenic cells
Q33905761Usage of heparan sulfate, integrins, and FAK in HPV16 infection
Q30583034Using total internal reflection fluorescence (TIRF) microscopy to visualize cortical actin and microtubules in the Drosophila syncytial embryo
Q42362594VCA nanobodies target N-WASp to reduce invadopodium formation and functioning.
Q55172315Vascular Morphogenesis in the Context of Inflammation: Self-Organization in a Fibrin-Based 3D Culture System.
Q58702541Vimentin Diversity in Health and Disease
Q35659629Virus activated filopodia promote human papillomavirus type 31 uptake from the extracellular matrix
Q30944807Virus movements on the plasma membrane support infection and transmission between cells
Q40531470Viruses That Exploit Actin-Based Motility for Their Replication and Spread
Q27348715Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level
Q27318774Visualization of phosphatidic acid fluctuations in the plasma membrane of living cells
Q30489687Wash functions downstream of Rho and links linear and branched actin nucleation factors
Q37434240Water flux in cell motility: expanding the mechanisms of membrane protrusion
Q64104326Wave patterns organize cellular protrusions and control cortical dynamics
Q31036801Wavelet-based multiscale analysis of bioimpedance data measured by electric cell-substrate impedance sensing for classification of cancerous and normal cells.
Q36023305hnRNP Q regulates Cdc42-mediated neuronal morphogenesis
Q35763102mDia1 and WAVE2 proteins interact directly with IRSp53 in filopodia and are involved in filopodium formation
Q38553239p53 regulates cytoskeleton remodeling to suppress tumor progression
Q52879772pERK1/2 Peripheral Recruitment and Filopodia Protrusion Augment Oligodendrocyte Progenitor Cell Migration: Combined Effects of PDGF-A and Fibronectin.
Q47713707α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion.
Q27310096α5β1 integrin recycling promotes Arp2/3-independent cancer cell invasion via the formin FHOD3.
Q35551725β3 integrin-EGF receptor cross-talk activates p190RhoGAP in mouse mammary gland epithelial cells.

Search more.