Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation

scientific article

Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-017-06147-6
P932PMC publication ID5651867
P698PubMed publication ID29057977

P50authorMitsuo IkebeQ103836858
Yoshikazu TsukasakiQ124634496
P2093author name stringTomonobu M Watanabe
Kangmin He
Tsuyoshi Sakai
P2860cites workA novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
Self-assembly of filopodia-like structures on supported lipid bilayersQ42360649
Three functionally distinct adhesions in filopodia: shaft adhesions control lamellar extension.Q42525821
Filopodia are required for cortical neurite initiation.Q46891046
PtdIns(3,4,5)P₃ is a regulator of myosin-X localization and filopodia formation.Q52604153
Phospholipid-dependent regulation of the motor activity of myosin X.Q52612413
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongationQ24655828
Filopodia: molecular architecture and cellular functionsQ28279460
Arp2/3 complex is important for filopodia formation, growth cone motility, and neuritogenesis in neuronal cellsQ28576273
Ena/VASP proteins have an anti-capping independent function in filopodia formationQ30444426
Filopodia formation in the absence of functional WAVE- and Arp2/3-complexesQ30477396
The motor activity of myosin-X promotes actin fiber convergence at the cell periphery to initiate filopodia formation.Q30480576
A myosin motor that selects bundled actin for motilityQ30482736
Single-molecule stepping and structural dynamics of myosin X.Q30494681
Myosin-X induces filopodia by multiple elongation mechanismQ30494868
The actin nucleating Arp2/3 complex contributes to the formation of axonal filopodia and branches through the regulation of actin patch precursors to filopodiaQ30503395
Myosin X transports Mena/VASP to the tip of filopodia.Q31065358
Design of active transport must be highly intricate: a possible role of myosin and Ena/VASP for G-actin transport in filopodiaQ33795702
Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotionQ33889491
Myosin-X, a novel myosin with pleckstrin homology domains, associates with regions of dynamic actin.Q33917620
Myosin-X is an unconventional myosin that undergoes intrafilopodial motility.Q34115035
The Stepping Pattern of Myosin X Is Adapted for Processive Motility on Bundled ActinQ34134758
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
The physics of filopodial protrusionQ34350863
Myosin-X: a MyTH-FERM myosin at the tips of filopodiaQ35576442
Myosin-X: a molecular motor at the cell's fingertipsQ36248392
The making of filopodiaQ36335794
Filopodia: the fingers that do the walkingQ36915801
Life at the leading edgeQ37894186
Filopodia initiation: focus on the Arp2/3 complex and forminsQ37942763
Vinculin-deficient PC12 cell lines extend unstable lamellipodia and filopodia and have a reduced rate of neurite outgrowthQ41430840
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)13685
P577publication date2017-10-20
P1433published inScientific ReportsQ2261792
P1476titleMyosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation
P478volume7

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cites work (P2860)
Q91334253Filopodia and focal adhesions: An integrated system driving branching morphogenesis in neuronal pathfinding and angiogenesis
Q61445970Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability
Q52724286Mammalian Oocytes Locally Remodel Follicular Architecture to Provide the Foundation for Germline-Soma Communication.
Q89545561Myosin X is required for efficient melanoblast migration and melanoma initiation and metastasis
Q90702016Optimized filopodia formation requires myosin tail domain cooperation
Q58104023Roles for Ena/VASP proteins in FMNL3-mediated filopodial assembly
Q88202227The Antiparallel Dimerization of Myosin X Imparts Bundle Selectivity for Processive Motility
Q94465899Tunneling Nanotubes and the Eye: Intercellular Communication and Implications for Ocular Health and Disease

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