An unconventional myosin required for cell polarization and chemotaxis

scientific article

An unconventional myosin required for cell polarization and chemotaxis is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2010PNAS..107.6918B
P356DOI10.1073/PNAS.0909796107
P8608Fatcat IDrelease_zlozvc6nbbd55dwpbe7tl63ec4
P932PMC publication ID2872422
P698PubMed publication ID20351273
P5875ResearchGate publication ID42639158

P50authorDavid R. SollQ5238846
Laura M. BreshearsQ52685360
P2093author name stringDeborah Wessels
Margaret A Titus
P2860cites workDrawing the tree of eukaryotic life based on the analysis of 2,269 manually annotated myosins from 328 speciesQ21092862
Myosin-X is a molecular motor that functions in filopodia formationQ24299253
The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membraneQ28284187
Myosin X regulates netrin receptors and functions in axonal path-findingQ28506167
Myosin-XVa is required for tip localization of whirlin and differential elongation of hair-cell stereociliaQ28593953
Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factorsQ29544703
G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motilityQ30480512
Mosaic complementation demonstrates a regulatory role for myosin VIIa in actin dynamics of stereociliaQ30481360
Rac regulation of chemotaxis and morphogenesis in DictyosteliumQ30835405
Myosin X transports Mena/VASP to the tip of filopodia.Q31065358
Myosin-X provides a motor-based link between integrins and the cytoskeleton.Q34322246
The PI3K-mediated activation of CRAC independently regulates adenylyl cyclase activation and chemotaxisQ34387628
Insights into morphogenesis from a simple developmental systemQ35825855
The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in DictyosteliumQ35862555
Signaling to Cytoskeletal Dynamics during ChemotaxisQ36181604
Myosins: tails (and heads) of functional diversityQ36197820
Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulationQ36273918
Molecular phylogeny and evolution of morphology in the social amoebas.Q36325466
Navigating signaling networks: chemotaxis in Dictyostelium discoideumQ36510423
The G protein beta subunit is essential for multiple responses to chemoattractants in DictyosteliumQ36535746
Sequential roles for myosin-X in BMP6-dependent filopodial extension, migration, and activation of BMP receptorsQ36639095
Highlighting the role of Ras and Rap during Dictyostelium chemotaxisQ37126989
Interstitial leukocyte migration and immune functionQ37246683
Chemoattractant-induced Ras activation during Dictyostelium aggregationQ40102452
Molecular genetics of signal transduction in DictyosteliumQ41114808
Effects of cAMP on single cell motility in DictyosteliumQ41465512
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule levelQ41978648
Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movementQ42053161
Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.Q42455765
The developmental regulation of single-cell motility in Dictyostelium discoideumQ42528253
Selection of chemotaxis mutants of Dictyostelium discoideum.Q42764357
Molecular genetic analysis of two G alpha protein subunits in DictyosteliumQ46001397
Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxisQ46458035
Sisyphus, the Drosophila myosin XV homolog, traffics within filopodia transporting key sensory and adhesion cargosQ47070932
Characterization of microtubule binding domains in the Arabidopsis kinesin-like calmodulin binding proteinQ47949260
MAX-1, a novel PH/MyTH4/FERM domain cytoplasmic protein implicated in netrin-mediated axon repulsion.Q52118712
A microtubule-binding myosin required for nuclear anchoring and spindle assembly.Q52560093
Cultivation and synchronous morphogenesis of Dictyostelium under controlled experimental conditions.Q54769657
Phosphorylation of Chemoattractant Receptors Is Not Essential for Chemotaxis or Termination of G-protein-mediated ResponsesQ62096099
Relationship of pseudopod extension to chemotactic hormone-induced actin polymerization in amoeboid cellsQ68488497
Changes in actin associated with the cytoskeleton following chemotactic stimulation of Dictyostelium discoideumQ70162610
Coronin involved in phagocytosis: dynamics of particle-induced relocalization visualized by a green fluorescent protein TagQ70787193
Molecular genetic analysis of myoC, a Dictyostelium myosin IQ71921643
A role for myosin VII in dynamic cell adhesionQ73670214
G protein signaling events are activated at the leading edge of chemotactic cellsQ77431001
Application of 2D and 3D DIAS to motion analysis of live cells in transmission and confocal microscopy imagingQ80223581
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectchemotaxisQ658145
P304page(s)6918-6923
P577publication date2010-03-29
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleAn unconventional myosin required for cell polarization and chemotaxis
P478volume107

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cites work (P2860)
Q506317574D Tumorigenesis Model for Quantitating Coalescence, Directed Cell Motility and Chemotaxis, Identifying Unique Cell Behaviors, and Testing Anticancer Drugs.
Q58173395A Cancer-Associated Mutation in Atypical Protein Kinase C Occurs in a Substrate-Specific Recruitment Motif
Q37616520Evolution and classification of myosins, a paneukaryotic whole-genome approach
Q30496448Expression of Y53A-actin in Dictyostelium disrupts the cytoskeleton and inhibits intracellular and intercellular chemotactic signaling
Q37107569Insights into the origin of metazoan filopodia and microvilli
Q47190656Loss of FrmB results in increased size of developmental structures during the multicellular development of Dictyostelium cells
Q45080215MyTH4, independent of its companion FERM domain, affects the organization of an intramacronuclear microtubule array and is involved in elongation of the macronucleus in Tetrahymena thermophila
Q37515120MyTH4-FERM myosins have an ancient and conserved role in filopod formation
Q26825835Myosin-X and disease
Q30513859Myosin-X functions in polarized epithelial cells
Q35576442Myosin-X: a MyTH-FERM myosin at the tips of filopodia
Q35789659Structural and functional insights on the Myosin superfamily
Q34454406The Dictyostelium prestalk inducer differentiation-inducing factor-1 (DIF-1) triggers unexpectedly complex global phosphorylation changes

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