| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCISIGNAL.2004068 |
| P698 | PubMed publication ID | 24045153 |
| P50 | author | Peter Joseph Jacques Parker | Q21165177 |
| Mark Linch | Q57304881 | ||
| Angus J.M. Cameron | Q58326489 | ||
| Andrew G Purkiss | Q96639913 | ||
| Phillip P Knowles | Q114562925 | ||
| Carine Rosse | Q114562926 | ||
| Philippe Riou | Q114562927 | ||
| Erika V Soriano | Q114562928 | ||
| Marta Sanz-Garcia | Q114562931 | ||
| Susanne Krüger Kjaer | Q38297251 | ||
| P2093 | author name string | Neil Q McDonald | |
| Yixiao Zhang | |||
| P2860 | cites work | The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation | Q22009927 |
| The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42 | Q22254751 | ||
| Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures | Q24290938 | ||
| Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity | Q24300954 | ||
| aPKC acts upstream of PAR-1b in both the establishment and maintenance of mammalian epithelial polarity | Q24301746 | ||
| Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface | Q24301761 | ||
| Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network | Q24301939 | ||
| Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment | Q24309071 | ||
| The protein kinase complement of the human genome | Q24324497 | ||
| An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3 | Q24682973 | ||
| Structures of the PKC-iota kinase domain in its ATP-bound and apo forms reveal defined structures of residues 533-551 in the C-terminal tail and their roles in ATP binding | Q27661351 | ||
| Substrate recognition mechanism of atypical protein kinase Cs revealed by the structure of PKCι in complex with a substrate peptide from Par-3 | Q27679032 | ||
| Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes | Q27684030 | ||
| Integrated genomic analyses of ovarian carcinoma | Q27860518 | ||
| The consensus coding sequences of human breast and colorectal cancers | Q27861035 | ||
| KIBRA is a novel substrate for protein kinase Czeta | Q28256148 | ||
| Myristylation and palmitylation of Src family members: the fats of the matter | Q28259697 | ||
| Willin and Par3 cooperatively regulate epithelial apical constriction through aPKC-mediated ROCK phosphorylation | Q28590637 | ||
| Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner | Q30479119 | ||
| Myosin-10 and actin filaments are essential for mitotic spindle function | Q30482632 | ||
| Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis | Q30484554 | ||
| Trafficking of Crumbs3 during cytokinesis is crucial for lumen formation | Q30491662 | ||
| An unconventional myosin required for cell polarization and chemotaxis | Q30494552 | ||
| A microtubule-binding myosin required for nuclear anchoring and spindle assembly. | Q52560093 | ||
| Tumor type-dependent function of the par3 polarity protein in skin tumorigenesis. | Q53145549 | ||
| The human Lgl polarity gene, Hugl-2, induces MET and suppresses Snail tumorigenesis. | Q53270407 | ||
| Aurothiomalate Inhibits Transformed Growth by Targeting the PB1 Domain of Protein Kinase Cι | Q57271956 | ||
| A synthetic peptide analog of the putative substrate-binding motif activates protein kinase C | Q57976395 | ||
| The overexpression and altered localization of the atypical protein kinase C λ/ι in breast cancer correlates with the pathologic type of these tumors | Q58323601 | ||
| Myosin-X induces filopodia by multiple elongation mechanism | Q30494868 | ||
| Par6B and atypical PKC regulate mitotic spindle orientation during epithelial morphogenesis | Q30499299 | ||
| Myosin-X functions in polarized epithelial cells | Q30513859 | ||
| Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer. | Q33920769 | ||
| Myosin-X is an unconventional myosin that undergoes intrafilopodial motility. | Q34115035 | ||
| Myosin-X provides a motor-based link between integrins and the cytoskeleton. | Q34322246 | ||
| Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer | Q34398455 | ||
| Crystal structure of the catalytic domain of human atypical protein kinase C-iota reveals interaction mode of phosphorylation site in turn motif | Q34446130 | ||
| Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota | Q34828123 | ||
| Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions | Q35071377 | ||
| Molecular recognitions in the MAP kinase cascades | Q35086083 | ||
| SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia | Q35572506 | ||
| Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity | Q35787307 | ||
| Modelling glandular epithelial cancers in three-dimensional cultures | Q36251934 | ||
| Coupling phosphoryl transfer and substrate interactions in protein kinases | Q36280698 | ||
| PATJ regulates tight junction formation and polarity in mammalian epithelial cells | Q36321518 | ||
| Unique substrate specificity and regulatory properties of PKC-epsilon: a rationale for diversity | Q36417286 | ||
| Cell signaling and function organized by PB1 domain interactions. | Q36584065 | ||
| Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis. | Q36881687 | ||
| Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators | Q37679354 | ||
| A novel PKC-ι inhibitor abrogates cell proliferation and induces apoptosis in neuroblastoma | Q39593833 | ||
| Protein kinase Ciota is required for pancreatic cancer cell transformed growth and tumorigenesis | Q39736038 | ||
| Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression | Q39850326 | ||
| Involvement of PKC-iota in glioma proliferation | Q40022122 | ||
| Amplification of PRKCI, located in 3q26, is associated with lymph node metastasis in esophageal squamous cell carcinoma | Q40054747 | ||
| Atypical protein kinase C iota is an oncogene in human non-small cell lung cancer | Q40365768 | ||
| The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl. | Q40664929 | ||
| Rac1 orientates epithelial apical polarity through effects on basolateral laminin assembly | Q40782515 | ||
| Cell polarity protein Lgl2 is lost or aberrantly localized in gastric dysplasia and adenocarcinoma: an immunohistochemical study | Q42453047 | ||
| Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae. | Q42473975 | ||
| Motor function and regulation of myosin X. | Q43678692 | ||
| High expression of KIBRA in low atypical protein kinase C-expressing gastric cancer correlates with lymphatic invasion and poor prognosis | Q43877393 | ||
| A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl. | Q44357555 | ||
| Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity | Q44844574 | ||
| PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity. | Q45998535 | ||
| Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis. | Q47397341 | ||
| Mitotic spindle misorientation in cancer--out of alignment and into the fire | Q47793757 | ||
| Interaction between PAR-3 and the aPKC-PAR-6 complex is indispensable for apical domain development of epithelial cells | Q47921771 | ||
| High expression of atypical protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence. | Q51808809 | ||
| P433 | issue | 293 | |
| P304 | page(s) | ra82 | |
| P577 | publication date | 2013-09-17 | |
| P1433 | published in | Science Signaling | Q7433604 |
| P1476 | title | A cancer-associated mutation in atypical protein kinase Cι occurs in a substrate-specific recruitment motif | |
| P478 | volume | 6 |
| Q38162656 | Atypical protein kinase Cι as a human oncogene and therapeutic target |
| Q35037676 | Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor |
| Q92633600 | Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo Pathway as a Feature of Chronic Disease |
| Q101574540 | Equivocal, explicit and emergent actions of PKC isoforms in cancer |
| Q36285296 | Mining for Candidate Genes Related to Pancreatic Cancer Using Protein-Protein Interactions and a Shortest Path Approach |
| Q36226960 | Phosphorylation of NR2B NMDA subunits by protein kinase C in arcuate nucleus contributes to inflammatory pain in rats |
| Q39286734 | Protein kinase C as a tumor suppressor |
| Q39098659 | Protein kinase C in cancer: The top five unanswered questions. |
| Q52669759 | Protein kinase C: perfectly balanced. |
| Q39173336 | Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor |
| Q64089124 | The Rho family GEF FARP2 is activated by aPKCι to control tight junction formation and polarity |
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