gene knockout causes destruction of intestinal structure and animal death in mice

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gene knockout causes destruction of intestinal structure and animal death in mice is …
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scholarly articleQ13442814

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P356DOI10.3748/WJG.V25.I5.584
P932PMC publication ID6371004
P698PubMed publication ID30774273

P2093author name stringChang Xu
Lei Ding
Kun Wang
Wen-Jing Li
Yu-Han Ding
P2860cites workExpression of tight-junction protein claudin-7 is an early event in gastric tumorigenesisQ30437572
The level of claudin-7 is reduced as an early event in colorectal carcinogenesisQ33817521
Claudin-7 is frequently overexpressed in ovarian cancer and promotes invasionQ33971294
Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell typesQ34210313
Claudin-7 inhibits human lung cancer cell migration and invasion through ERK/MAPK signaling pathwayQ35099927
A non-tight junction function of claudin-7-Interaction with integrin signaling in suppressing lung cancer cell proliferation and detachment.Q35750069
Claudins and epithelial paracellular transportQ36387912
The claudin family of proteins in human malignancy: a clinical perspectiveQ37302556
Regulation of epithelial proliferation by tight junction proteinsQ38021500
Claudins and cancer: Fall of the soldiers entrusted to protect the gate and keep the barrier intactQ38508321
Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma.Q38729094
Intestinal epithelial claudins: expression and regulation in homeostasis and inflammationQ39298268
Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cellsQ39976263
A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cellsQ40583001
Site-specific and directional gene replacement mediated by Cre recombinaseQ40848889
Circulating tumor cells exhibit stem cell characteristics in an orthotopic mouse model of colorectal cancerQ41353471
Site- and time-specific gene targeting in the mouseQ43591560
Tissue-specific and inducible Cre-mediated recombination in the gut epitheliumQ44999476
Overexpression of claudin-7 decreases the paracellular Cl- conductance and increases the paracellular Na+ conductance in LLC-PK1 cellsQ46520833
Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice.Q50600432
NMDA receptor-dependent synaptic reinforcement as a crucial process for memory consolidation.Q51073604
Claudin-7 indirectly regulates the integrin/FAK signaling pathway in human colon cancer tissue.Q51354330
Reduced expression of claudin-7 correlates with invasion and metastasis in squamous cell carcinoma of the esophagus.Q53625198
Changes in the expression of claudins in active ulcerative colitis.Q54498951
Conditional Gene Knockout Using Cre RecombinaseQ56114286
Aberrant expression of claudin-4 and -7 in hepatocytes in the cirrhotic human liverQ57146476
Megaintestine in claudin-15-deficient miceQ80612306
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectgene knockoutQ1133550
Claudin-7Q24775955
colorectal carcinomaQ25493920
P304page(s)584-599
P577publication date2019-02-07
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titlegene knockout causes destruction of intestinal structure and animal death in mice
P478volume25

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Q92155709Role of Claudin Proteins in Regulating Cancer Stem Cells and Chemoresistance-Potential Implication in Disease Prognosis and Therapycites workP2860

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