PAR2 activation interrupts E-cadherin adhesion and compromises the airway epithelial barrier: protective effect of beta-agonists.

scientific article

PAR2 activation interrupts E-cadherin adhesion and compromises the airway epithelial barrier: protective effect of beta-agonists. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPLUNG.00046.2006
P8608Fatcat IDrelease_c6lqcnvnxfcwbcor72zp6gajrq
P698PubMed publication ID16714334

P2093author name stringD Michael Shasby
Dana R Ries
Michael C Winter
Sandra S Shasby
P2860cites workSegregation of receptor and ligand regulates activation of epithelial growth factor receptorQ24298164
Protease-activated receptors in human airways: upregulation of PAR-2 in respiratory epithelium from patients with asthmaQ34100306
Effects of beta-agonists on airway epithelial cells.Q35016403
Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptorQ36324985
Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context.Q36834868
Histamine and thrombin modulate endothelial focal adhesion through centripetal and centrifugal forcesQ37352056
Rap1 regulates the formation of E-cadherin-based cell-cell contacts.Q40535764
Histamine selectively interrupts VE-cadherin adhesion independently of capacitive calcium entryQ40541215
Rap1 regulates E-cadherin-mediated cell-cell adhesionQ40551198
Cockroach proteases increase IL-8 expression in human bronchial epithelial cells via activation of protease-activated receptor (PAR)-2 and extracellular-signal-regulated kinaseQ40610163
Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability.Q40641504
Development of cystic fibrosis and noncystic fibrosis airway cell linesQ40658319
Protease-activated receptor 2 mediates eosinophil infiltration and hyperreactivity in allergic inflammation of the airwayQ40695518
Proteinase-activated receptor-2-mediated matrix metalloproteinase-9 release from airway epithelial cellsQ40855526
Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanismQ41717146
House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1.Q44172242
PAR2 activation alters colonic paracellular permeability in mice via IFN-gamma-dependent and -independent pathwaysQ44934665
Protease-activated receptor-2 activation induces acute lung inflammation by neuropeptide-dependent mechanismsQ46253083
Abrogation of bronchial eosinophilic inflammation and attenuated eotaxin content in protease-activated receptor 2-deficient miceQ46477914
Proteinase-activated receptor 2 activation in the airways enhances antigen-mediated airway inflammation and airway hyperresponsiveness through different pathways.Q47835931
Rap1 GTPase regulation of adherens junction positioning and cell adhesion.Q52545327
Cdc42 regulates the restoration of endothelial barrier function.Q52552672
P433issue4
P304page(s)L628-35
P577publication date2006-05-19
P1433published inAmerican Journal of Physiology - Lung Cellular and Molecular PhysiologyQ4352992
P1476titlePAR2 activation interrupts E-cadherin adhesion and compromises the airway epithelial barrier: protective effect of beta-agonists.
P478volume291

Reverse relations

cites work (P2860)
Q34353956A highly potent agonist to protease-activated receptor-2 reveals apical activation of the airway epithelium resulting in Ca2+-regulated ion conductance
Q40060160Airway epithelial barrier dysfunction in the pathogenesis and prognosis of respiratory tract diseases in childhood and adulthood
Q38194648Airway epithelial barrier function regulates the pathogenesis of allergic asthma.
Q36645364Cell-cell adhesion in lung endothelium
Q40034901Compromised E-cadherin adhesion and epithelial barrier function with activation of G protein-coupled receptors is rescued by Y-to-F mutations in beta-catenin
Q39201211Decreased expression of kallikrein-related peptidase 13: possible contribution to metastasis of human oral cancer
Q34698968Detrimental effects of albuterol on airway responsiveness requires airway inflammation and is independent of β-receptor affinity in murine models of asthma
Q37836200Do cell junction protein mutations cause an airway phenotype in mice or humans?
Q42085431Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro
Q39757549H1 and PAR2 receptors enhance delivery of immune-competent cells and molecules by interrupting E-cadherin adhesion in epithelia.
Q35115872HER2 activation results in β-catenin-dependent changes in pulmonary epithelial permeability
Q38791937High glucose induces dysfunction of airway epithelial barrier through down-regulation of connexin 43.
Q34339205House dust mite interactions with airway epithelium: role in allergic airway inflammation
Q47996385House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium
Q36857029Innate immune responses in house dust mite allergy
Q34103720Knockout mice reveal key roles for claudin 18 in alveolar barrier properties and fluid homeostasis
Q30487603MMP9 modulates tight junction integrity and cell viability in human airway epithelia
Q94921992More Than Just a Barrier: The Immune Functions of the Airway Epithelium in Asthma Pathogenesis
Q40086023PAR-2 activation and LPS synergistically enhance inflammatory signaling in airway epithelial cells by raising PAR expression level and interleukin-8 release
Q44630306PAR2-induced inflammatory responses in human kidney tubular epithelial cells
Q48307273Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia
Q23912006Proteases in agricultural dust induce lung inflammation through PAR-1 and PAR-2 activation
Q40145975Proteinase-activated receptor 4 stimulation-induced epithelial-mesenchymal transition in alveolar epithelial cells
Q30426145Septin-2 mediates airway epithelial barrier function in physiologic and pathologic conditions.
Q36491366Shear stress regulates aquaporin-5 and airway epithelial barrier function
Q37834484The significant role of mast cells in cancer

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