Activation of STAT3 by the c-Fes protein-tyrosine kinase

scientific article published on March 1998

Activation of STAT3 by the c-Fes protein-tyrosine kinase is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.273.12.7072
P698PubMed publication ID9507017
P5875ResearchGate publication ID51304437

P2093author name stringJove R
Nelson KL
Rogers JA
Smithgall TE
Bowman TL
P2860cites workCo-expression with BCR induces activation of the FES tyrosine kinase and phosphorylation of specific N-terminal BCR tyrosine residuesQ24336377
Tyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOSQ24646851
Activation and association of Stat3 with Src in v-Src-transformed cell linesQ24650319
STATs and gene regulationQ29547796
Production of high-titer helper-free retroviruses by transient transfectionQ29547802
Transcriptional responses to polypeptide ligands: the JAK-STAT pathwayQ29620287
Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/AblQ36365946
Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related proteinQ36894127
STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell lineQ37625031
Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells.Q37684441
Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93fes, STAT1 p91, and STAT3 p92 in polymorphonuclear leukocytesQ38361508
Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21(WAF1/Cip1) by STAT5Q40022229
Signaling through the hematopoietic cytokine receptors.Q40444894
STATs: signal transducers and activators of transcriptionQ40974978
Constitutive activation of JAK1 in Src-transformed cellsQ41132498
P210 and P190(BCR/ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family membersQ41145752
Roles of the JAK-STAT system in signal transduction via cytokine receptorsQ41239435
Jak-STAT signaling induced by the v-abl oncogeneQ41292981
Interleukin-3, Erythropoietin, and Prolactin Activate a STAT5-like Factor in Lymphoid CellsQ41326609
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoproteinQ41326706
Activation of Fes tyrosine kinase by gp130, an interleukin-6 family cytokine signal transducer, and their associationQ41346200
Chicken myeloid stem cells infected by retroviruses carrying the v-fps oncogene do not require exogenous growth factors to differentiate in vitroQ41363861
Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation.Q41841116
Autophosphorylation of the Fes tyrosine kinase. Evidence for an intermolecular mechanism involving two kinase domain tyrosine residuesQ42064004
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)7072-7077
P577publication date1998-03-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleActivation of STAT3 by the c-Fes protein-tyrosine kinase
P478volume273

Reverse relations

cites work (P2860)
Q40321346A growth-suppressive function for the c-fes protein-tyrosine kinase in colorectal cancer
Q24291572A point mutation in the N-terminal coiled-coil domain releases c-Fes tyrosine kinase activity and survival signaling in myeloid leukemia cells
Q33869231A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.
Q73047684Abnormal Stat activation, hematopoietic homeostasis, and innate immunity in c-fes-/- mice
Q30165193Activation of STAT3 by the Src family kinase Hck requires a functional SH3 domain
Q38312043Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity
Q38325370Activation of the Notch1/STAT3/Twist signaling axis promotes gastric cancer progression
Q39902329Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1.
Q28142393Cell volume-dependent phosphorylation of proteins of the cortical cytoskeleton and cell-cell contact sites. The role of Fyn and FER kinases
Q35291843Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts
Q24296817Closing in on the biological functions of Fps/Fes and Fer
Q37980587Co-expression vs. co-infection using baculovirus expression vectors in insect cell culture: Benefits and drawbacks
Q28207618Constitutive activation of STAT transcription factors in acute myelogenous leukemia
Q43649346Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells
Q33941411Control of myeloid differentiation and survival by Stats
Q40633129Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma Cells
Q79405603Engagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway
Q28139718FER kinase activation of Stat3 is determined by the N-terminal sequence
Q40671016Fes tyrosine kinase promotes survival and terminal granulocyte differentiation of factor-dependent myeloid progenitors (32D) and activates lineage-specific transcription factors
Q31029794Genetic complementation of cytokine signaling identifies central role of kinases in hematopoietic cell proliferation
Q38359739Inhibition of Bcr-Abl kinase activity by PD180970 blocks constitutive activation of Stat5 and growth of CML cells
Q28346555Inhibition of STAT3 signaling leads to apoptosis of leukemic large granular lymphocytes and decreased Mcl-1 expression
Q36383594Integration of HIV-1 caused STAT3-associated B cell lymphoma in an AIDS patient
Q31947141Lymphokine dependence of STAT3 activation produced by surface immunoglobulin cross-linking and by phorbol ester plus calcium ionophore treatment in B cells
Q94093929Methylisoindigo and Its Bromo-Derivatives Are Selective Tyrosine Kinase Inhibitors, Repressing Cellular Stat3 Activity, and Target CD133+ Cancer Stem Cells in PDAC
Q38310016STAT3 and importins are novel mediators of early molecular and cellular responses in experimental duodenal ulceration.
Q33733773STAT3 is a substrate of SYK tyrosine kinase in B-lineage leukemia/lymphoma cells exposed to oxidative stress
Q29617571STATs in oncogenesis
Q35120899Signal transducer and activator of transcription-3, inflammation, and cancer: how intimate is the relationship?.
Q38354192Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck
Q38336235Suppressor of cytokine signaling 3 expression in anaplastic large cell lymphoma.
Q33959954Targeted disruption of the murine fps/fes proto-oncogene reveals that Fps/Fes kinase activity is dispensable for hematopoiesis.
Q33247592The KRAB-associated co-repressor KAP-1 is a coiled-coil binding partner, substrate and activator of the c-Fes protein tyrosine kinase
Q30165112The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.
Q40890115The nonreceptor protein-tyrosine kinase c-Fes is involved in fibroblast growth factor-2-induced chemotaxis of murine brain capillary endothelial cells
Q44487732The role of c-Fes in vascular endothelial growth factor-A-mediated signaling by endothelial cells
Q34658532Tyrosine kinase oncogenes in normal hematopoiesis and hematological disease
Q43280614fps/fes knockout mice display a lactation defect and the fps/fes tyrosine kinase is a component of E-cadherin-based adherens junctions in breast epithelial cells during lactation

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