Engagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway

scientific article published on 04 December 2006

Engagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1004858595
P356DOI10.1038/SJ.ONC.1210092
P698PubMed publication ID17146444

P2093author name stringWang L
Kurosaki T
Corey SJ
P2860cites workRegulation of the phospholipase C-gamma2 pathway in B cellsQ24290431
Activation and association of Stat3 with Src in v-Src-transformed cell linesQ24650319
Sustained activation of Lyn tyrosine kinase in vivo leads to autoimmunityQ24670363
c-Src activates both STAT1 and STAT3 in PDGF-stimulated NIH3T3 cellsQ28252598
Dominant negative stat3 mutant inhibits interleukin-6-induced Jak-STAT signal transductionQ28278147
Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathwayQ28609398
Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagementQ28615625
The STATs of cancer--new molecular targets come of ageQ29614601
Jaks and STATs: biological implicationsQ29619657
Lymphokine dependence of STAT3 activation produced by surface immunoglobulin cross-linking and by phorbol ester plus calcium ionophore treatment in B cellsQ31947141
The Jak-STAT pathwayQ33899139
The chicken B cell line DT40: a novel tool for gene disruption experimentsQ34166907
The role of signal transducer and activator of transcription factors in leukemogenesisQ35628327
Phosphorylation of two regulatory tyrosine residues in the activation of Bruton's tyrosine kinase via alternative receptorsQ36601174
Hematopoietic cells express two forms of lyn kinase differing by 21 amino acids in the amino terminusQ36691185
Src directly tyrosine-phosphorylates STAT5 on its activation site and is involved in erythropoietin-induced signaling pathwayQ38295577
Microarray analysis of Lyn-deficient B cells reveals germinal center-associated nuclear protein and other genes associated with the lymphoid germinal centerQ38343391
Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domainQ39745564
Signal transduction by the B-cell antigen receptor.Q40374565
Interleukin-3 protects Bcr-Abl-transformed hematopoietic progenitor cells from apoptosis induced by Bcr-Abl tyrosine kinase inhibitorsQ40708026
Distinct region of the granulocyte colony-stimulating factor receptor mediates proliferative signaling through activation of Janus kinase 2 and p44/42 mitogen-activated protein kinaseQ40754539
The Src-family kinase Lck can induce STAT3 phosphorylation and DNA binding activityQ40909044
The Janus protein tyrosine kinases in hematopoietic cytokine signalingQ40921717
Regulation of the Jak/STAT signalling pathwayQ40964979
Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferationQ41044152
Activation of STAT3 by the c-Fes protein-tyrosine kinaseQ41050807
Requirement of Src kinase Lyn for induction of DNA synthesis by granulocyte colony-stimulating factor.Q41062090
Enhanced DNA-binding activity of a Stat3-related protein in cells transformed by the Src oncoproteinQ41326706
Rapid STAT phosphorylation via the B cell receptor. Modulatory role of CD19.Q41699439
Constitutive and specific activation of STAT3 by BCR-ABL in embryonic stem cells.Q44488212
The Lyn tyrosine kinase negatively regulates neutrophil integrin signalingQ44521258
STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expressionQ45265413
Fc gamma receptor type IIb induced recruitment of inositol and protein phosphatases to the signal transductory complex of human B-cellQ73533444
Requirements of src family kinase activity associated with CD45 for myeloma cell proliferation by interleukin-6Q77725508
P433issue20
P304page(s)2851-2859
P577publication date2006-12-04
P1433published inOncogeneQ1568657
P1476titleEngagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway
P478volume26