Requirement of Src kinase Lyn for induction of DNA synthesis by granulocyte colony-stimulating factor.

scientific article

Requirement of Src kinase Lyn for induction of DNA synthesis by granulocyte colony-stimulating factor. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.273.6.3230
P698PubMed publication ID9452436
P5875ResearchGate publication ID13779167

P50authorMinoru TakataQ56599905
P2093author name stringP M Dombrosky-Ferlan
S J Corey
G Romero
T Kurosaki
A D Donnenberg
S Zuo
E Krohn
P Zorich
P2860cites workThree different mRNAs encoding human granulocyte colony-stimulating factor receptorQ24556594
Granulocyte colony-stimulating factor receptor signaling involves the formation of a three-component complex with Lyn and Syk protein-tyrosine kinasesQ24563242
Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activationQ24563701
Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domainsQ24682612
Three-dimensional structure of the tyrosine kinase c-SrcQ27734749
Crystal structure of the Src family tyrosine kinase HckQ27734750
Expression cloning of a receptor for murine granulocyte colony-stimulating factorQ28592097
Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylationQ34166097
Binding of 125I-labeled granulocyte colony-stimulating factor to normal murine hemopoietic cellsQ34193056
The intracellular signal transduction mechanism of interleukin 5 in eosinophils: the involvement of lyn tyrosine kinase and the Ras-Raf-1-MEK-microtubule-associated protein kinase pathwayQ36364828
The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cellsQ36485178
Clustering of Syk is sufficient to induce tyrosine phosphorylation and release of allergic mediators from rat basophilic leukemia cellsQ36550003
Distinct cytoplasmic regions of the human granulocyte colony-stimulating factor receptor involved in induction of proliferation and maturationQ36756480
Clustered syk tyrosine kinase domains trigger phagocytosisQ37730766
A new cytokine receptor superfamilyQ37887843
DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases.Q40021748
Signaling through the hematopoietic cytokine receptors.Q40444894
Cytokine signaling through nonreceptor protein tyrosine kinasesQ40506447
The alphas, betas, and kinases of cytokine receptor complexesQ40857127
Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cellsQ41118648
Association between the PDGF receptor and members of the src family of tyrosine kinasesQ41725198
Association of p60c-src with polyoma virus middle-T antigen abrogating mitosis-specific activationQ43717627
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)3230-3235
P577publication date1998-02-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleRequirement of Src kinase Lyn for induction of DNA synthesis by granulocyte colony-stimulating factor
P478volume273

Reverse relations

cites work (P2860)
Q40757996Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase
Q40900402Association of Lyn tyrosine kinase to the GM-CSF and IL-3 receptor common betac subunit and role of Src tyrosine kinases in DNA synthesis and anti-apoptosis
Q42061078Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34(+) cells
Q42664472CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML
Q49239291Chronic neutrophilic leukemia: new science and new diagnostic criteria
Q40754539Distinct region of the granulocyte colony-stimulating factor receptor mediates proliferative signaling through activation of Janus kinase 2 and p44/42 mitogen-activated protein kinase
Q79405603Engagement of the B-cell antigen receptor activates STAT through Lyn in a Jak-independent pathway
Q40146009Establishment and characterization of a novel imatinib-sensitive chronic myeloid leukemia cell line MYL, and an imatinib-resistant subline MYL-R showing overexpression of Lyn.
Q40352398G-CSF induced reactive oxygen species involves Lyn-PI3-kinase-Akt and contributes to myeloid cell growth
Q42051165G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase
Q37459752G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation
Q37127231Getting to the stem of chronic myeloid leukaemia
Q33940371Granulocyte colony-stimulating factor induces ERK5 activation, which is differentially regulated by protein-tyrosine kinases and protein kinase C. Regulation of cell proliferation and survival
Q33780538Granulocyte colony-stimulating factor: molecular mechanisms of action during steady state and 'emergency' hematopoiesis.
Q24291603Interaction between growth arrest-DNA damage protein 34 and Src kinase Lyn negatively regulates genotoxic apoptosis
Q24299293Interactions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesis
Q28210841Interleukin-6, CD45 and the src-kinases in myeloma cell proliferation
Q35211026Interleukin-6-induced proliferation of human myeloma cells associated with CD45 molecules
Q40904570Involvement of Shc and Cbl-PI 3-kinase in Lyn-dependent proliferative signaling pathways for G-CSF.
Q37608488Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization
Q54384748Linking stress granulopoiesis to protein synthesis through GADD34.
Q54577779Loss of GADD34 induces early age-dependent deviation to the myeloid lineage.
Q24305025Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors
Q38248429Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.
Q58483487Multiple Signals Mediate Proliferation, Differentiation, and Survival from the Granulocyte Colony-stimulating Factor Receptor in Myeloid 32D Cells
Q27852275Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML
Q38363901Repression of c-Cbl leads to enhanced G-CSF Jak-STAT signaling without increased cell proliferation
Q61444646Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes
Q58262544Signal transduction of the cytokine receptor
Q36795284Signal transduction pathways that contribute to myeloid differentiation
Q33861766Signaling mechanisms of cytokine receptors and their perturbances in disease.
Q35849188Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis
Q36900749Sustained receptor activation and hyperproliferation in response to granulocyte colony-stimulating factor (G-CSF) in mice with a severe congenital neutropenia/acute myeloid leukemia-derived mutation in the G-CSF receptor gene.
Q38284004Systems approach to phagocyte production and activation: neutrophils and monocytes
Q92128519Targeting Tyrosine Kinases in Acute Myeloid Leukemia: Why, Who and How?
Q49887981Targeting few to help hundreds: JAK, MAPK and ROCK pathways as druggable targets in atypical chronic myeloid leukemia.
Q74066499The SH2 domain-containing protein tyrosine phosphatase SHP-1 is induced by granulocyte colony-stimulating factor (G-CSF) and modulates signaling from the G-CSF receptor
Q34166907The chicken B cell line DT40: a novel tool for gene disruption experiments
Q35920901The interplay between Src family kinases and receptor tyrosine kinases
Q30501052The non-receptor tyrosine kinase Lyn controls neutrophil adhesion by recruiting the CrkL-C3G complex and activating Rap1 at the leading edge

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