Activin Signals through SMAD2/3 to Increase Photoreceptor Precursor Yield during Embryonic Stem Cell Differentiation

scientific article

Activin Signals through SMAD2/3 to Increase Photoreceptor Precursor Yield during Embryonic Stem Cell Differentiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.STEMCR.2017.06.021
P932PMC publication ID5599185
P698PubMed publication ID28781074

P50authorColin J. BarnstableQ46154689
P2093author name stringEvgenya Y Popova
Amy Q Lu
P2860cites workSB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7Q24299813
Chromatin and transcriptional signatures for Nodal signaling during endoderm formation in hESCsQ24312034
HEB and E2A function as SMAD/FOXH1 cofactorsQ24320356
Characterization of human FAST-1, a TGF beta and activin signal transducerQ24323087
Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activinsQ28305397
Genome-wide identification of Smad/Foxh1 targets reveals a role for Foxh1 in retinoic acid regulation and forebrain developmentQ28506244
Docosahexaenoic acid promotes photoreceptor differentiation without altering Crx expressionQ28571212
Generation of three-dimensional retinal tissue with functional photoreceptors from human iPSCsQ28651997
Non-Smad pathways in TGF-beta signalingQ29620040
Generation of Rx+/Pax6+ neural retinal precursors from embryonic stem cellsQ33913871
Generation of retinal cells from mouse and human induced pluripotent stem cellsQ34017132
Activin/Nodal signalling in stem cells.Q34462176
Making the gradient: thyroid hormone regulates cone opsin expression in the developing mouse retinaQ34597372
Stepwise differentiation of pluripotent stem cells into retinal cellsQ34607711
Efficient generation of retinal progenitor cells from human embryonic stem cells.Q35036440
Efficient retina formation requires suppression of both Activin and BMP signaling pathways in pluripotent cellsQ35453492
Rax Homeoprotein Regulates Photoreceptor Cell Maturation and Survival in Association with Crx in the Postnatal Mouse RetinaQ35914019
Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod PhotoreceptorsQ35990735
Activin/Nodal Signaling Supports Retinal Progenitor Specification in a Narrow Time Window during Pluripotent Stem Cell NeuralizationQ36221242
Characterization of Three-Dimensional Retinal Tissue Derived from Human Embryonic Stem Cells in Adherent Monolayer Cultures.Q36301644
Defining the integration capacity of embryonic stem cell-derived photoreceptor precursorsQ36632655
Modeling early retinal development with human embryonic and induced pluripotent stem cellsQ37377238
NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCsQ37377843
Restoration of vision after transplantation of photoreceptorsQ37466380
Transcriptional regulation of photoreceptor development and homeostasis in the mammalian retinaQ37774553
Cell replacement and visual restoration by retinal sheet transplantsQ38024553
Differentiation of human embryonic stem cells into cone photoreceptors through simultaneous inhibition of BMP, TGFβ and Wnt signalingQ38829843
Retinal Organoids from Pluripotent Stem Cells Efficiently Recapitulate Retinogenesis.Q38884982
Transcriptional Control by the SMADsQ38906095
Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.Q38984753
Differential CRX and OTX2 expression in human retina and retinoblastomaQ39811699
Specific protein kinase C isoforms are required for rod photoreceptor differentiation.Q40344765
The major cell populations of the mouse retina.Q40838448
Multiple roles of Activin/Nodal, bone morphogenetic protein, fibroblast growth factor and Wnt/β-catenin signalling in the anterior neural patterning of adherent human embryonic stem cell culturesQ42076307
Activin/Nodal signalling maintains pluripotency by controlling Nanog expression.Q43121593
Conserved and divergent roles of FGF signaling in mouse epiblast stem cells and human embryonic stem cellsQ43140844
STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina.Q44956663
Activin A maintains pluripotency of human embryonic stem cells in the absence of feeder layersQ46404347
Fate of embryonic stem cell derivatives implanted into the vitreous of a slow retinal degenerative mouse modelQ46622264
Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-beta, activin, and bone morphogenetic protein-inducible enhancerQ47724219
Mouse embryonic stem cell culture for generation of three-dimensional retinal and cortical tissuesQ48769089
iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration MiceQ49305633
Photoreceptor Fate Determination in the Vertebrate Retina.Q50517685
Retinoic acid promotes differentiation of photoreceptors in vitro.Q51132475
Activin A promotes progenitor differentiation into photoreceptors in rodent retina.Q52171164
Activin family members in the developing chick retina: expression patterns, protein distribution, and in vitro effects.Q52176528
Analysis of embryonic stem cell-derived osteogenic cultures.Q52572177
Production and transplantation of retinal cells from human and mouse embryonic stem cellsQ84356413
LSD1-Mediated Demethylation of H3K4me2 Is Required for the Transition from Late Progenitor to Differentiated Mouse Rod PhotoreceptorQ85951343
P433issue3
P921main subjectphotoreceptor proteinQ7187894
stem cell differentiationQ14864672
P304page(s)838-852
P577publication date2017-07-18
P1433published inStem Cell ReportsQ27725039
P1476titleActivin Signals through SMAD2/3 to Increase Photoreceptor Precursor Yield during Embryonic Stem Cell Differentiation
P478volume9

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cites work (P2860)
Q89824316Chromatin accessibility analysis reveals regulatory dynamics of developing human retina and hiPSC-derived retinal organoids
Q48164257Generation of Photoreceptor Precursors from Mouse Embryonic Stem Cells
Q64967797Perspectives of small molecule inhibitors of activin receptor‑like kinase in anti‑tumor treatment and stem cell differentiation (Review).
Q90428747Pluripotential stem cells as replacement therapy in degenerative diseases of the eye