Queer current and pacemaker: the hyperpolarization-activated cation current in neurons

scientific article published on January 1996

Queer current and pacemaker: the hyperpolarization-activated cation current in neurons is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1146/ANNUREV.PH.58.030196.001503
P698PubMed publication ID8815797
P5875ResearchGate publication ID14389094

P2093author name stringPape HC
P921main subjectqueerQ51415
P304page(s)299-327
P577publication date1996-01-01
P1433published inAnnual Review of PhysiologyQ567364
P1476titleQueer current and pacemaker: the hyperpolarization-activated cation current in neurons
P478volume58

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cites work (P2860)
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Q77066340H-current: properties of a neuronal and network pacemaker
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Q37996815HCN and KV7 (M-) channels as targets for epilepsy treatment
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Q34777401HCN channels in behavior and neurological disease: too hyper or not active enough?
Q39446354HCN channels segregate stimulation-evoked movement responses in neocortex and allow for coordinated forelimb movements in rodents
Q39793659HCN hyperpolarization-activated cation channels strengthen virtual nicotinic EPSPs and thereby elevate synaptic amplification in rat sympathetic neurons.
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Q58791990HCN2 Ion Channels Play a Central Role in Inflammatory and Neuropathic Pain
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Q34187424Helical secondary structure of the external S3-S4 linker of pacemaker (HCN) channels revealed by site-dependent perturbations of activation phenotype
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Q47728162High-conductance states and A-type K+ channels are potential regulators of the conductance-current balance triggered by HCN channels.
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Q91952719Human cerebrospinal fluid promotes spontaneous gamma oscillations in the hippocampus in vitro
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Q28569491Hyperpolarization-activated channels HCN1 and HCN4 mediate responses to sour stimuli
Q37350615Hyperpolarization-activated current (I(h)) contributes to excitability of primary sensory neurons in rats
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Q46184350Hyperpolarization-activated current (Ih) in primary auditory neurons
Q44475055Hyperpolarization-activated current Ih disconnects somatic and dendritic spike initiation zones in layer V pyramidal neurons
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Q46726646Hyperpolarization-activated cyclic nucleotide-gated cation channels regulate auditory coincidence detection in nucleus laminaris of the chick.
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Q24336296Identification of a gene encoding a hyperpolarization-activated pacemaker channel of brain
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Q48125876In vitro characterization of cell-level neurophysiological diversity in the rostral nucleus reuniens of adult mice.
Q44991693In vivo intracellular responses of the medial geniculate neurones to acoustic stimuli in anaesthetized guinea pigs
Q40581993Inactivation in HCN channels results from reclosure of the activation gate: desensitization to voltage
Q40571096Increased HCN channel driven inward rectification in benign cramp fasciculation syndrome.
Q28584777Increased excitability and inward rectification in layer V cortical pyramidal neurons in the epileptic mutant mouse Stargazer
Q43906359Influence of the hyperpolarization-activated cation current, I(h), on the electrotonic properties of the distal apical dendrites of hippocampal CA1 pyramidal neurones
Q41949012Integrated allosteric model of voltage gating of HCN channels
Q36550629Integration of metabolic stimuli in the hypothalamic arcuate nucleus
Q48672351Integrative properties and transfer function of cortical neurons initiating absence seizures in a rat genetic model.
Q34082402Interactions Between Membrane Conductances Underlying Thalamocortical Slow-Wave Oscillations
Q37220455Interneuron diversity in layers 2-3 of monkey prefrontal cortex
Q44336712Interplay between activation of GIRK current and deactivation of Ih modifies temporal integration of excitatory input in CA1 pyramidal cells
Q53728003Intra-axonal recording from large sensory myelinated axons: demonstration of impaired membrane conductances in early experimental diabetes.
Q46892835Intracellular activity of cortical and thalamic neurones during high-voltage rhythmic spike discharge in Long-Evans rats in vivo
Q48450921Intrinsic and synaptic mechanisms determining the timing of neuron population activity during hippocampal theta oscillation
Q46162105Intrinsic firing dynamics of vestibular nucleus neurons.
Q34313878Intrinsic membrane properties of pre-oromotor neurons in the intermediate zone of the medullary reticular formation
Q51373078Intrinsic membrane properties underlying spontaneous tonic firing in neostriatal cholinergic interneurons.
Q43875677Intrinsic physiological properties of cat retinal ganglion cells.
Q47393773Intrinsic physiological properties of rat retinal ganglion cells with a comparative analysis.
Q35029598Intrinsic processing in the mammalian superior colliculus
Q41956126Intrinsic properties of the sodium sensor neurons in the rat median preoptic nucleus
Q44502588Intrinsic spontaneous activity and subthreshold oscillations in neurones of the rat dorsal column nuclei in culture.
Q24339387Investigation of hyperpolarization-activated cyclic nucleotide-gated channels in interstitial cells of Cajal of human bladder
Q36712331Involvement of HCN Channel in Muscarinic Inhibitory Action on Tonic Firing of Dorsolateral Striatal Cholinergic Interneurons
Q48232816Involvement of I(h) in dopamine modulation of tonic firing in striatal cholinergic interneurons
Q36178989Ion channel development, spontaneous activity, and activity-dependent development in nerve and muscle cells
Q48164908Ionic Mechanisms of Burst Firing in Dissociated Purkinje Neurons
Q28363178Ionic basis of the caesium-induced depolarisation in rat supraoptic nucleus neurones
Q44416449Ionic currents underlying rhythmic bursting of ventral mossy cells in the developing mouse dentate gyrus
Q34502373Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons.
Q47634896Ionic mechanisms in the generation of subthreshold oscillations and action potential clustering in entorhinal layer II stellate neurons
Q47852103Ionic mechanisms of autorhythmic firing in rat cerebellar Golgi cells
Q52170053Ischaemic changes in refractoriness of human cutaneous afferents under threshold-clamp conditions.
Q37430180Ischemia-induced cell depolarization: does the hyperpolarization-activated cation channel HCN2 affect the outcome after stroke in mice?
Q54113931Ischemic resistance of cutaneous afferents and motor axons in patients with amyotrophic lateral sclerosis.
Q42526963K(+)-induced changes in the properties of the hyperpolarization-activated cation current I(h) in rat CA1 pyramidal cells.
Q33317280K+ channel regulator KCR1 suppresses heart rhythm by modulating the pacemaker current If.
Q40466646Keeping Pace with Pacemaker Channels.
Q36299724Kinetic relationship between the voltage sensor and the activation gate in spHCN channels
Q24317591Kir2.4: a novel K+ inward rectifier channel associated with motoneurons of cranial nerve nuclei
Q36956963Kv4 accessory protein DPPX (DPP6) is a critical regulator of membrane excitability in hippocampal CA1 pyramidal neurons
Q46487845Kv7/KCNQ/M and HCN/h, but not KCa2/SK channels, contribute to the somatic medium after-hyperpolarization and excitability control in CA1 hippocampal pyramidal cells.
Q33582367Lack of delta waves and sleep disturbances during non-rapid eye movement sleep in mice lacking alpha1G-subunit of T-type calcium channels
Q48636905Lack of regulation by intracellular Ca2+ of the hyperpolarization-activated cation current in rat thalamic neurones
Q43959251Lateral hypothalamic GAD65 neurons are spontaneously firing and distinct from orexin- and melanin-concentrating hormone neurons
Q48033664Layer- and subregion-specific differences in the neurophysiological properties of rat medial prefrontal cortex pyramidal neurons
Q51847464Lobule-specific membrane excitability of cerebellar Purkinje cells.
Q42182136Local anaesthetics block hyperpolarization-activated inward current in rat small dorsal root ganglion neurones
Q35871110Local control of postinhibitory rebound spiking in CA1 pyramidal neuron dendrites
Q35086524Localization and function of Ih channels in a small neural network
Q64917279Locally injected ivabradine inhibits carrageenan-induced pain and inflammatory responses via hyperpolarization-activated cyclic nucleotide-gated (HCN) channels.
Q30484398Lock-and-key mechanisms of cerebellar memory recall based on rebound currents.
Q30490207Loss of dendritic HCN1 subunits enhances cortical excitability and epileptogenesis
Q37400271MEG3, HCN3 and linc01105 influence the proliferation and apoptosis of neuroblastoma cells via the HIF-1α and p53 pathways
Q44654343Mammalian retinal bipolar cells express inwardly rectifying K+ currents (IKir) with a different distribution than that of Ih.
Q21559638Mathematical model of bursting in dissociated purkinje neurons
Q46972545Mechanism underlying rebound excitation in retinal ganglion cells
Q33920891Mechanisms and distribution of ion channels in retinal ganglion cells: using temperature as an independent variable.
Q28245870Mechanisms of postinhibitory rebound and its modulation by serotonin in excitatory swim motor neurons of the medicinal leech
Q43823538Melatonin generates an outward potassium current in rat suprachiasmatic nucleus neurones in vitro independent of their circadian rhythm
Q43908352Membrane potential bistability is controlled by the hyperpolarization-activated current I(H) in rat cerebellar Purkinje neurons in vitro
Q46620292Membrane properties of excitatory and inhibitory neurons in the rat prepositus hypoglossi nucleus
Q43701707Membrane properties of principal neurons of the lateral superior olive
Q48506285Membrane resting potential of thalamocortical relay neurons is shaped by the interaction among TASK3 and HCN2 channels
Q58110029Mitochondrial Depolarization Stimulates Vascular Repair-Relevant Functions of CD34 Cells via Reactive Oxygen Species-Induced Nitric Oxide Generation
Q24681855Mode shifts in the voltage gating of the mouse and human HCN2 and HCN4 channels
Q38064103Modeling the generation of output by the cerebellar nuclei
Q47649009Moderate Cortical Cooling Eliminates Thalamocortical Silent States during Slow Oscillation.
Q43674627Modification of the pacemaker activity of vestibular neurons in brainstem slices during vestibular compensation in the guinea pig.
Q58566453Modulation of Hyperpolarization-Activated Inward Current and Thalamic Activity Modes by Different Cyclic Nucleotides
Q48733481Modulation of IH by 5-HT in neonatal rat motoneurones in vitro: mediation through a phosphorylation independent action of cAMP.
Q48163815Modulation of a pacemaker current through Ca(2+)-induced stimulation of cAMP production.
Q74306948Modulation of a presynaptic hyperpolarization-activated cationic current (I(h)) at an excitatory synaptic terminal in the rat auditory brainstem
Q37807755Modulation of cortical excitability induced by repetitive transcranial magnetic stimulation: Influence of timing and geometrical parameters and underlying mechanisms
Q47371810Modulation of thalamocortical oscillations by TRIP8b, an auxiliary subunit for HCN channels.
Q43640015Modulation of the hyperpolarisation-activated current, Ih, in rat facial motoneurones in vitro by ZD-7288.
Q48130669Modulation of the hyperpolarization-activated cation current of rat thalamic relay neurones by intracellular pH.
Q31778271Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS.
Q28180008Molecular basis for the different activation kinetics of the pacemaker channels HCN2 and HCN4
Q24684146Molecular characterization of a slowly gating human hyperpolarization-activated channel predominantly expressed in thalamus, heart, and testis
Q31853820Molecular cloning and characterization of a novel phospholemman-like protein from rat hippocampus
Q41032353Molecular identification of a hyperpolarization-activated channel in sea urchin sperm
Q48428838Molecular identity, ontogeny, and cAMP modulation of the hyperpolarization-activated current in vestibular ganglion neurons.
Q53889028Molecular mechanism of cAMP modulation of HCN pacemaker channels.
Q79275942Morphological analysis of the hyperpolarization‐activated cyclic nucleotide‐gated cation channel 1 (HCN1) immunoreactive bipolar cells in the rabbit retina
Q36436615Movements near the gate of a hyperpolarization-activated cation channel
Q80694667Multiple conductances cooperatively regulate spontaneous bursting in mouse olfactory bulb external tufted cells
Q43099177Multiple effects of serotonin and acetylcholine on hyperpolarization-activated inward current in locomotor activity-related neurons in Cfos-EGFP mice
Q30472667Multiple ionic mechanisms mediate inhibition of rat motoneurones by inhalation anaesthetics
Q37265961Multisensory integration in mesencephalic trigeminal neurons in Xenopus tadpoles
Q28348754Muscarinic activation of inwardly rectifying K(+) conductance reduces EPSPs in rat hippocampal CA1 pyramidal cells
Q45713982Muscarinic induction of hippocampal gamma oscillations requires coupling of the M1 receptor to two mixed cation currents
Q92659070Muscarinic modulation of M and h currents in gerbil spherical bushy cells
Q37258146Mutation analysis of the hyperpolarization-activated cyclic nucleotide-gated channels HCN1 and HCN2 in idiopathic generalized epilepsy
Q40862135Mutations in the S4 domain of a pacemaker channel alter its voltage dependence
Q44211155NPY sensitivity and postsynaptic properties of heterotopic neurons in the MAM model of malformation-associated epilepsy
Q47650690Na(+) -Ca(2+) Exchanger, Leak K(+) Channel and Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Comediate the Histamine-Induced Excitation on Rat Inferior Vestibular Nucleus Neurons
Q33639690Neonatal seizures: an update on mechanisms and management
Q90162687Nerve excitability differences in slow and fast motor axons of the rat: more than just Ih
Q46453505Nerve function and dysfunction in acute intermittent porphyria
Q42440232Neuromedin U Depolarizes Rat Hypothalamic Paraventricular Nucleus Neurons In Vitro by Enhancing IH Channel Activity
Q34178989Neuronal hyperpolarization-activated pacemaker channels drive neuropathic pain.
Q30438269Neuronal specializations for the processing of interaural difference cues in the chick
Q48636898Neurotensin inhibition of the hyperpolarization-activated cation current (Ih) in the rat substantia nigra pars compacta implicates the protein kinase C pathway
Q43681718Niflumic acid reduces the hyperpolarization-activated current (I(h)) in rod photoreceptor cells
Q48250680Nitric Oxide Modulates HCN Channels in Magnocellular Neurons of the Supraoptic Nucleus of Rats by an S-Nitrosylation-Dependent Mechanism
Q30401440Noise-induced plasticity of KCNQ2/3 and HCN channels underlies vulnerability and resilience to tinnitus
Q34217875Non-synaptic ion channels in insects--basic properties of currents and their modulation in neurons and skeletal muscles
Q45173465Noradrenergic modulation of XII motoneuron inspiratory activity does not involve alpha2-receptor inhibition of the Ih current or presynaptic glutamate release.
Q42043668Noradrenergic modulation of the hyperpolarization-activated cation current (Ih) in dopamine neurons of the ventral tegmental area
Q38554624Not so funny anymore: pacing channels are cloned.
Q90633397Novel Potassium Channels in Kidney Mitochondria: The Hyperpolarization-Activated and Cyclic Nucleotide-Gated HCN Channels
Q35653002Novel vistas of calcium-mediated signalling in the thalamus
Q75411999Olfactory bulb glomeruli: external tufted cells intrinsically burst at theta frequency and are entrained by patterned olfactory input
Q49162675On the origin and suddenness of absences in genetic absence models
Q44349901Opioid inhibition of hippocampal interneurons via modulation of potassium and hyperpolarization-activated cation (Ih) currents.
Q36076020Opposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels
Q79133403Overexpression of a hyperpolarization-activated cation current (Ih) channel gene modifies the firing activity of identified motor neurons in a small neural network
Q33515020P-loop residues critical for selectivity in K channels fail to confer selectivity to rabbit HCN4 channels
Q34453808PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis
Q42454411Pacemaker channels in mouse thalamocortical neurones are regulated by distinct pathways of cAMP synthesis
Q42665335Pacemaker channels produce an instantaneous current.
Q33977867Pacemaker oscillations in heart and brain: a key role for hyperpolarization-activated cation channels
Q51541840Paraesthesiae induced by prolonged high frequency stimulation of human cutaneous afferents.
Q36183551Partial nerve injury induces electrophysiological changes in conducting (uninjured) nociceptive and nonnociceptive DRG neurons: Possible relationships to aspects of peripheral neuropathic pain and paresthesias.
Q46140081Participation of sodium currents in burst generation and control of membrane excitability in mesencephalic trigeminal neurons.
Q36956861Parvalbumin-positive basket interneurons in monkey and rat prefrontal cortex
Q93003617PatcherBot: a single-cell electrophysiology robot for adherent cells and brain slices
Q36840738Pathophysiology of HCN channels
Q48691829Pattern generation for walking and searching movements of a stick insect leg. II. Control of motoneuronal activity
Q73632725Pb2+ inhibits the hyperpolarization-activated current in acutely isolated dorsal root ganglion neurons
Q44238738Pentobarbital depressant effects are independent of GABA receptors in auditory thalamic neurons
Q48921400Perinatal changes of I(h) in phrenic motoneurons
Q37259795Perineural administration of dexmedetomidine in combination with bupivacaine enhances sensory and motor blockade in sciatic nerve block without inducing neurotoxicity in rat
Q37406653Perineural dexmedetomidine added to ropivacaine causes a dose-dependent increase in the duration of thermal antinociception in sciatic nerve block in rat
Q47942450Periodicity of thalamic spindle waves is abolished by ZD7288,a blocker of Ih.
Q48491890Periodicity of thalamic synchronized oscillations: the role of Ca2+-mediated upregulation of Ih.
Q47648985Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex
Q38422586Peripheral hyperpolarization-activated cyclic nucleotide-gated channels contribute to inflammation-induced hypersensitivity of the rat temporomandibular joint.
Q42380122Perisomatic changes in h-channels regulate depressive behaviors following chronic unpredictable stress
Q42214350Persistently modified h-channels after complex febrile seizures convert the seizure-induced enhancement of inhibition to hyperexcitability
Q42000023Pharmacological characterization of the inwardly-rectifying current in the smooth muscle cells of the rat bladder
Q51435813Pharmacological isolation of the synaptic and nonsynaptic components of the GABA-mediated biphasic response in rat CA1 hippocampal pyramidal cells.
Q44064239Pharmacological upregulation of h-channels reduces the excitability of pyramidal neuron dendrites
Q44030381Phosphorylation-dependent differences in the activation properties of distal and proximal dendritic Na+ channels in rat CA1 hippocampal neurons
Q35175109Physiological characterization of vestibular efferent brainstem neurons using a transgenic mouse model
Q48670598Physiological properties of central amygdala neurons: species differences
Q46840656Plasticity of intrinsic excitability during long-term depression is mediated through mGluR-dependent changes in I(h) in hippocampal CA1 pyramidal neurons.
Q48239783Plasticity of inwardly rectifying conductances following a corticospinal lesion in human subjects
Q42043141Plateau potentials in developing antennal-lobe neurons of the moth, Manduca sexta.
Q40214882Pore topology of the hyperpolarization-activated cyclic nucleotide-gated channel from sea urchin sperm
Q48531115Postinhibitory rebound during locomotor-like activity in neonatal rat motoneurons in vitro
Q44185990Postnatal development of the hyperpolarization-activated excitatory current Ih in mouse hippocampal pyramidal neurons.
Q28583228Postnatal expression pattern of HCN channel isoforms in thalamic neurons: relationship to maturation of thalamocortical oscillations.
Q35999614Postnatal maturation of somatostatin-expressing inhibitory cells in the somatosensory cortex of GIN mice
Q51861062Postnatal maturation of the hyperpolarization-activated cation current, I(h), in trigeminal sensory neurons.
Q44178904Postsynaptic action mechanism of somatostatin on the membrane excitability in spinal substantia gelatinosa neurons of juvenile rats
Q44010671Postsynaptic application of a cAMP analogue reverses long-term potentiation in hippocampal CA1 pyramidal neurons
Q37151158Postsynaptic mechanisms underlying the excitatory action of histamine on medial vestibular nucleus neurons in rats
Q40081684Pre- and postsynaptic serotoninergic excitation of globus pallidus neurons
Q28596091Presence of a Chaotic Region at the Sleep-Wake Transition in a Simplified Thalamocortical Circuit Model
Q44322851Presynaptic cyclic nucleotide-gated ion channels modulate neurotransmission in the mammalian olfactory bulb.
Q73389336Presynaptic facilitation by hyperpolarization-activated pacemaker channels
Q58286967Presynatic expression of HCN channel subunits in cerebellar basket cells
Q48884138Properties and functional implications of I (h) in hippocampal area CA3 interneurons
Q74583796Properties and functional roles of hyperpolarization-gated currents in guinea-pig retinal rods
Q33923594Properties of GABAergic neurons in the rostral solitary tract nucleus in mice
Q48161215Properties of a hyperpolarization-activated cation current in interneurons in the rat lateral geniculate nucleus
Q28364054Properties of hyperpolarization-activated pacemaker current defined by coassembly of HCN1 and HCN2 subunits and basal modulation by cyclic nucleotide
Q48818919Properties of low-threshold motor axons in the human median nerve
Q43752075Propofol suppresses a hyperpolarization-activated inward current in rat hippocampal CA1 neurons
Q37377604Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels
Q46902401Queer currents, steady rhythms, and drunken da neurons. Focus on "hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice".
Q37810893Rate control with ivabradine: angina pectoris and beyond
Q34051188Reactive oxygen species alters the electrophysiological properties and raises [Ca2+]i in intracardiac ganglion neurons
Q46015905Recessive loss-of-function mutation in the pacemaker HCN2 channel causing increased neuronal excitability in a patient with idiopathic generalized epilepsy.
Q28573202Reciprocal modulation of I (h) and I (TASK) in thalamocortical relay neurons by halothane
Q44426481Reexamination of the role of hyperpolarization-activated cation channels in short- and long-term plasticity at hippocampal mossy fiber synapses
Q60198376Regularizing firing patterns of rat subthalamic neurons ameliorates parkinsonian motor deficits
Q34056344Regulated expression of HCN channels and cAMP levels shape the properties of the h current in developing rat hippocampus
Q34171697Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.
Q34606323Regulation of firing frequency in nociceptive neurons by pro-inflammatory mediators.
Q28346769Regulation of hyperpolarization-activated HCN channel gating and cAMP modulation due to interactions of COOH terminus and core transmembrane regions
Q44368217Regulation of orexin neurons by the monoaminergic and cholinergic systems.
Q45023548Regulation of the hyperpolarization-activated cationic current Ih in mouse hippocampal pyramidal neurones by vitronectin, a component of extracellular matrix
Q48094630Regulation of the rebound depolarization and spontaneous firing patterns of deep nuclear neurons in slices of rat cerebellum
Q30846936Release of monoamines and nitric oxide is involved in the modulation of hyperpolarization-activated inward current during acute thalamic hypoxia
Q48431809Resonance (approximately 10 Hz) of excitatory networks in motor cortex: effects of voltage-dependent ion channel blockers
Q79936365Resonant or not, two amplification modes of proprioceptive inputs by persistent inward currents in spinal motoneurons
Q33939085Respiratory network function in the isolated brainstem-spinal cord of newborn rats
Q48436673Response of thalamocortical neurons to hypoxia: a whole-cell patch-clamp study.
Q47681387Resting membrane properties of locust muscle and their modulation I. Actions of the neuropeptides YGGFMRFamide and proctolin
Q48545817Role for the subthreshold currents ILeak and IH in the homeostatic control of excitability in neocortical somatostatin-positive inhibitory neurons.
Q37041634Role of Ih in differentiating the dynamics of the gastric and pyloric neurons in the stomatogastric ganglion of the lobster, Homarus americanus
Q51325903Role of Ih in the firing pattern of mammalian cold thermoreceptor endings.
Q46715590Role of a novel maintained low-voltage-activated inward current permeable to sodium and calcium in pacemaking of insect neurosecretory neurons
Q34180971Role of hyperpolarization-activated currents for the intrinsic dynamics of isolated retinal neurons
Q44535862Role of the hyperpolarization-activated cation current (Ih) in pacemaker activity in area postrema neurons of rat brain slices
Q46308455Role of the hyperpolarization-activated current Ih in somatosensory neurons
Q34170619Rundown of the hyperpolarization-activated KAT1 channel involves slowing of the opening transitions regulated by phosphorylation
Q42920172Segmental oscillators in axial motor circuits of the salamander: distribution and bursting mechanisms.
Q38531931Seizure-induced plasticity of h channels in entorhinal cortical layer III pyramidal neurons
Q48354386Selective Modulation of Histaminergic Inputs on Projection Neurons of Cerebellum Rapidly Promotes Motor Coordination via HCN Channels.
Q41735290Selective depolarization of interneurons in the early posttraumatic dentate gyrus: involvement of the Na(+)/K(+)-ATPase
Q30510970Sensorimotor function is modulated by the serotonin receptor 1d, a novel marker for gamma motor neurons
Q38021306Sensory neurons, ion channels, inflammation and the onset of neuropathic pain.
Q44066926Separable gating mechanisms in a Mammalian pacemaker channel.
Q77921066Serotonergic modulation of hyperpolarization-activated current in acutely isolated rat dorsal root ganglion neurons
Q47899794Serotonin suppresses subthreshold and suprathreshold oscillatory activity of rat inferior olivary neurones in vitro
Q55447957Short and Long-Term Attentional Firing Rates Can Be Explained by ST-Neuron Dynamics.
Q41044579Slow and persistent postinhibitory rebound acts as an intrinsic short-term memory mechanism
Q42608566Slow conformational changes of the voltage sensor during the mode shift in hyperpolarization-activated cyclic-nucleotide-gated channels.
Q51407746Slowly inactivating sodium current (I(NaP)) underlies single-spike activity in rat subthalamic neurons.
Q51233300Sodium-dependent potassium channels in leech P neurons.
Q33721637Spatial distribution of NA+ and K+ channels in spinal dorsal horn neurones: role of the soma, axon and dendrites in spike generation
Q34600381Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons.
Q34113463Specificity of cold thermotransduction is determined by differential ionic channel expression
Q35862354Spike resonance properties in hippocampal O-LM cells are dependent on refractory dynamics
Q47825407Spike-triggered averages for passive and resonant neurons receiving filtered excitatory and inhibitory synaptic drive.
Q26744099Spontaneous Neuronal Activity in Developing Neocortical Networks: From Single Cells to Large-Scale Interactions
Q51504277Spontaneous activity of solitary dopaminergic cells of the retina.
Q48008062State-dependent contribution of the hyperpolarization-activated Na+/K+ and persistent Na+ currents to respiratory rhythmogenesis in vivo
Q89115776Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease
Q41935751Stress Impairs Prefrontal Cortical Function via D1 Dopamine Receptor Interactions With Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Q46910050Structural and functional determinants in the S5-P region of HCN-encoded pacemaker channels revealed by cysteine-scanning substitutions
Q40594035Structural elements of instantaneous and slow gating in hyperpolarization-activated cyclic nucleotide-gated channels
Q27645597Structure and Rearrangements in the Carboxy-Terminal Region of SpIH Channels
Q47858733Submillisecond kinetics and low efficacy of parallel fibre-Golgi cell synaptic currents in the rat cerebellum
Q52245422Substance P regulates Ih via a NK-1 receptor in vagal sensory neurons of the ferret.
Q51393192Subthreshold oscillation of the membrane potential in magnocellular neurones of the rat supraoptic nucleus.
Q45713980Subthreshold sodium current from rapidly inactivating sodium channels drives spontaneous firing of tuberomammillary neurons
Q48259982Subthreshold sodium currents and pacemaking of subthalamic neurons: modulation by slow inactivation
Q30437516Subunit-specific effects of isoflurane on neuronal Ih in HCN1 knockout mice
Q30437738Suppression of ih contributes to propofol-induced inhibition of mouse cortical pyramidal neurons
Q44376317Suppression of the hyperpolarization-activated inward current contributes to the inhibitory actions of propofol on rat CA1 and CA3 pyramidal neurons
Q21132286Sustained maximal voluntary contraction produces independent changes in human motor axons and the muscle they innervate
Q30360691Synaptic control of motoneuronal excitability.
Q47877119Synchronization of strongly coupled excitatory neurons: relating network behavior to biophysics
Q41897716Synchronized network activity in developing rat hippocampus involves regional hyperpolarization-activated cyclic nucleotide-gated (HCN) channel function.
Q38125277T-type Ca2+ channels in normal and abnormal brain functions
Q94468683Temperature effects on synaptic transmission and neuronal function in the visual thalamus
Q48948121Temperature influences neuronal activity and CO2/pH sensitivity of locus coeruleus neurons in the bullfrog, Lithobates catesbeianus
Q46006194Temporal synaptic tagging by I(h) activation and actin: involvement in long-term facilitation and cAMP-induced synaptic enhancement.
Q30486735The Concise Guide to PHARMACOLOGY 2013/14: ion channels
Q83226124The HCN domain couples voltage gating and cAMP response in hyperpolarization-activated cyclic nucleotide-gated channels
Q64084232The Hyperpolarization-Activated HCN4 Channel is Important for Proper Maintenance of Oscillatory Activity in the Thalamocortical System
Q30839844The Ih Channel Gene Promotes Synaptic Transmission and Coordinated Movement in Drosophila melanogaster.
Q44433374The Role of the Hyperpolarization-Activated Cationic CurrentIhin the Timing of Interictal Bursts in the Neonatal Hippocampus
Q33944447The S4-S5 linker couples voltage sensing and activation of pacemaker channels.
Q48367196The SCN is comprised of a population of coupled oscillators
Q89026045The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function
Q29032115The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis
Q37270133The action of high K+ and aglycaemia on the electrical properties and synaptic transmission in rat intracardiac ganglion neurones in vitro
Q34004305The action potential in mammalian central neurons
Q37806162The depolarizing action of GABA controls early network activity in the developing hippocampus
Q36514764The distribution and targeting of neuronal voltage-gated ion channels
Q40277118The enhancement of HCN channel instantaneous current facilitated by slow deactivation is regulated by intracellular chloride concentration.
Q35147010The fast and slow ups and downs of HCN channel regulation.
Q37034572The h channel mediates location dependence and plasticity of intrinsic phase response in rat hippocampal neurons.
Q34108299The h current is a candidate mechanism for regulating the sliding modification threshold in a BCM-like synaptic learning rule.
Q28145953The human gene coding for HCN2, a pacemaker channel of the heart
Q48128133The hyperpolarization-activated HCN1 channel is important for motor learning and neuronal integration by cerebellar Purkinje cells
Q28585488The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart
Q44598487The influences of Ih on temporal summation in hippocampal CA1 pyramidal neurons: a modeling study
Q43109802The membrane response of hippocampal CA3b pyramidal neurons near rest: Heterogeneity of passive properties and the contribution of hyperpolarization-activated currents
Q37548296The modulation by intensity of the processing of interaural timing cues for localizing sounds
Q35548575The multiple personalities of h-channels
Q30583731The pelvis-kidney junction contains HCN3, a hyperpolarization-activated cation channel that triggers ureter peristalsis
Q50623756The persistent sodium current generates pacemaker activities in the central pattern generator for locomotion and regulates the locomotor rhythm.
Q33722384The possible roles of hyperpolarization-activated cyclic nucleotide channels in regulating pacemaker activity in colonic interstitial cells of Cajal
Q41910234The role of H-current in regulating strength and frequency of thalamic network oscillations
Q35058506The role of histamine and the tuberomamillary nucleus in the nervous system
Q84226873The role of hyperpolarization-activated cationic current in spike-time precision and intrinsic resonance in cortical neurons in vitro
Q34578323The role of synaptic ion channels in synaptic plasticity
Q49084353The role of the hyperpolarization-activated current in modulating rhythmic activity in the isolated respiratory network of mice.
Q34215888The sleep relay--the role of the thalamus in central and decentral sleep regulation
Q44435286The sleep-modulating peptide cortistatin augments the h-current in hippocampal neurons.
Q35828454The stomatogastric nervous system as a model for studying sensorimotor interactions in real-time closed-loop conditions
Q30832676The thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture.
Q43494068The voltage dependence of I(h) in human myelinated axons
Q48554379Thermodynamic properties of hyperpolarization-activated current (Ih) in a subgroup of primary sensory neurons.
Q42282268Theta-frequency selectivity in the somatic spike-triggered average of rat hippocampal pyramidal neurons is dependent on HCN channels
Q41702491Threshold tracking techniques in the study of human peripheral nerve
Q48473410Tonic and bursting activity in the cuneate nucleus of the chloralose-anesthetized cat.
Q37699493Transcriptional and epigenetic regulation of Hebbian and non-Hebbian plasticity
Q36352062Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures
Q51432024Trial-to-trial variability and state-dependent modulation of auditory-evoked responses in cortex.
Q50641169Tryptophan-scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation.
Q44249830Two forms of electrical resonance at theta frequencies, generated by M-current, h-current and persistent Na+ current in rat hippocampal pyramidal cells
Q22009483Two pacemaker channels from human heart with profoundly different activation kinetics
Q27319461Two types of interneurons in the mouse lateral geniculate nucleus are characterized by different h-current density
Q44619542Unmyelinated axons in the rat hippocampus hyperpolarize and activate an H current when spike frequency exceeds 1 Hz
Q73174340Upregulation of the hyperpolarization-activated cation current after chronic compression of the dorsal root ganglion
Q48130658Upregulation of the hyperpolarization-activated cation current in rat thalamic relay neurones by acetazolamide
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