A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.

scientific article published on 25 July 2017

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2017NatCo...8..133Y
P356DOI10.1038/S41467-017-00171-W
P932PMC publication ID5527107
P698PubMed publication ID28743963

P50authorQing WangQ87010726
P2093author name stringQiuyun Chen
Yufeng Yao
Qiulun Lu
Yubin Yu
Zhenkun Hu
P2860cites workThe unfolded protein response: integrating stress signals through the stress sensor IRE1αQ24293771
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell deathQ24298384
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Epidemiology and risk profile of heart failureQ24630778
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Identification of association of common AGGF1 variants with susceptibility for Klippel-Trenaunay syndrome using the structure association programQ24645040
ER stress-induced cell death mechanismsQ27027638
Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart DiseaseQ27340828
Signal integration in the endoplasmic reticulum unfolded protein responseQ27860577
Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosisQ28275274
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alphaQ28512201
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulumQ28512249
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox stateQ28572472
The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAsQ29615910
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunitiesQ29617768
Quality control in the endoplasmic reticulumQ29619929
Aggf1 acts at the top of the genetic regulatory hierarchy in specification of hemangioblasts in zebrafishQ30567955
ERK2 but not ERK1 induces epithelial-to-mesenchymal transformation via DEF motif-dependent signaling eventsQ33789562
β-AR blockers suppresses ER stress in cardiac hypertrophy and heart failureQ34071906
MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis and growth.Q34324565
Dilated cardiomyopathy caused by aberrant endoplasmic reticulum quality control in mutant KDEL receptor transgenic miceQ34344775
Capillary perfusion and wall shear stress are restored in the coronary circulation of hypertrophic right ventricle.Q51084506
AGGF1 protects from myocardial ischemia/reperfusion injury by regulating myocardial apoptosis and angiogenesis.Q55058312
The spatial pattern of coronary capillaries in patients with dilated, ischemic, or inflammatory cardiomyopathyQ81781606
Depletion of cardiac 14-3-3η protein adversely influences pathologic cardiac remodeling during myocardial infarction after coronary artery ligation in miceQ86195933
Angiogenic factor AGGF1 promotes therapeutic angiogenesis in a mouse limb ischemia modelQ34460354
Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translationQ34719370
Orchestrating the unfolded protein response in health and diseaseQ35001604
Enhanced cardiac PI3Kα signalling mitigates arrhythmogenic electrical remodelling in pathological hypertrophy and heart failureQ35673862
Endoplasmic reticulum stress implicated in the development of renal fibrosisQ35882857
Regression of pathological cardiac hypertrophy: signaling pathways and therapeutic targetsQ36281111
ER stress and neurodegenerative diseasesQ36362415
Signals from the stressed endoplasmic reticulum induce C/EBP-homologous protein (CHOP/GADD153).Q36561426
Visiting the ER: the endoplasmic reticulum as a target for therapeutics in traffic related diseasesQ36903301
A p21-ZEB1 complex inhibits epithelial-mesenchymal transition through the microRNA 183-96-182 cluster.Q37546891
ER stress in cardiovascular diseaseQ37632850
Endoplasmic reticulum stress as a therapeutic target in cardiovascular diseaseQ37804650
Biology of Endoplasmic Reticulum Stress in the HeartQ37808904
The progression of hypertensive heart diseaseQ37832070
Protein folding stress in neurodegenerative diseases: a glimpse into the ER.Q37834769
Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesisQ37849479
Protein secretion and the endoplasmic reticulum.Q38018918
Endoplasmic reticulum stress in nonalcoholic fatty liver diseaseQ38027194
Ablation of C/EBP homologous protein attenuates endoplasmic reticulum-mediated apoptosis and cardiac dysfunction induced by pressure overloadQ38342543
AGGF1 is a novel anti-inflammatory factor associated with TNF-α-induced endothelial activationQ39158588
Haploinsufficiency of Klippel-Trenaunay syndrome gene Aggf1 inhibits developmental and pathological angiogenesis by inactivating PI3K and AKT and disrupts vascular integrity by activating VE-cadherinQ39492127
CHOP gene expression in response to endoplasmic-reticular stress requires NFY interaction with different domains of a conserved DNA-binding elementQ39607669
MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillationQ40036365
Ectopic expression of CHOP (GADD153) induces apoptosis in M1 myeloblastic leukemia cellsQ41157654
Essential Role of Smooth Muscle STIM1 in Hypertension and Cardiovascular Dysfunction.Q41440623
Regulation of apoptosis by the unfolded protein response.Q42159220
Transcriptional activation of the Prox1 gene by HIF-1α and HIF-2α in response to hypoxiaQ45715998
Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima IndiansQ46966552
Functional characterization of Klippel-Trenaunay syndrome gene AGGF1 identifies a novel angiogenic signaling pathway for specification of vein differentiation and angiogenesis during embryogenesisQ47073902
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)133
P577publication date2017-07-25
P1433published inNature CommunicationsQ573880
P1476titleA non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure
P478volume8

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