scholarly article | Q13442814 |
P50 | author | Alessia Finotti | Q54585393 |
Jessica Gasparello | Q57601361 | ||
Valentino Bezzerri | Q60628566 | ||
P2093 | author name string | Roberto Gambari | |
Marco Cipolli | |||
Baroukh Maurice Assael | |||
Claudio Sorio | |||
Antonio Vella | |||
Elisa Calcaterra | |||
P2860 | cites work | Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome | Q24301073 |
The human Shwachman-Diamond syndrome protein, SBDS, associates with ribosomal RNA | Q24304508 | ||
The chemotaxis defect of Shwachman-Diamond Syndrome leukocytes | Q24306310 | ||
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway | Q24531184 | ||
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins | Q27860890 | ||
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR | Q28144113 | ||
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis | Q28246808 | ||
Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase | Q28251762 | ||
mTOR and cancer therapy | Q28268516 | ||
Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR) | Q28291383 | ||
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells | Q29547557 | ||
Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial | Q29618031 | ||
Mutations in SBDS are associated with Shwachman-Diamond syndrome | Q33963285 | ||
Non-Diamond Blackfan anemia disorders of ribosome function: Shwachman Diamond syndrome and 5q- syndrome | Q34173140 | ||
JAKs and STATs in immunity, immunodeficiency, and cancer | Q34321767 | ||
Regulation of mTORC1 and its impact on gene expression at a glance | Q34342717 | ||
Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancer | Q34483617 | ||
Shwachman-Diamond syndrome: clinical phenotypes | Q34743107 | ||
STAT3 is necessary for proliferation and survival in colon cancer-initiating cells | Q34971936 | ||
Activity of everolimus (RAD001) in relapsed and/or refractory multiple myeloma: a phase I study. | Q35236076 | ||
STAT proteins: From normal control of cellular events to tumorigenesis | Q35540165 | ||
Signal transducer and activator of transcription (STAT) signalling and T-cell lymphomas. | Q36048656 | ||
Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes | Q36115659 | ||
FACS analysis of Stat3/5 signaling reveals sensitivity to G-CSF and IL-6 as a significant prognostic factor in pediatric AML: a Children's Oncology Group report | Q36619682 | ||
The route to development of myelodysplastic syndrome/acute myeloid leukaemia in Shwachman-Diamond syndrome: the role of ageing, karyotype instability, and acquired chromosome anomalies. | Q51817148 | ||
Detection of CFTR protein in human leukocytes by flow cytometry. | Q53093562 | ||
Dual PI3K/mTOR inhibition shows antileukemic activity in MLL-rearranged acute myeloid leukemia. | Q54315033 | ||
STAT3 is a negative regulator of granulopoiesis but is not required for G-CSF-dependent differentiation | Q57054852 | ||
JAK2 V617F is a rare finding in de novo acute myeloid leukemia, but STAT3 activation is common and remains unexplained | Q58289362 | ||
Shwachman syndrome as mutator phenotype responsible for myeloid dysplasia/neoplasia through karyotype instability and chromosomes 7 and 20 anomalies | Q82108621 | ||
Incidence of Shwachman-Diamond syndrome | Q84782423 | ||
Utility of lymphoblastoid cell lines | Q37395487 | ||
Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis. | Q37402798 | ||
Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation | Q37467580 | ||
Cytokine production by bone marrow mononuclear cells in inherited bone marrow failure syndromes | Q37595168 | ||
Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignancies | Q37779489 | ||
Biological and clinical aspects of interleukin 6. | Q37832897 | ||
Lymphoblastoid Cell lines: a Continuous in Vitro Source of Cells to Study Carcinogen Sensitivity and DNA Repair | Q38189401 | ||
Targeting PI3K/Akt/mTOR Signaling in Cancer | Q38208314 | ||
Revisiting STAT3 signalling in cancer: new and unexpected biological functions | Q38262473 | ||
SOCS3 regulates the plasticity of gp130 signaling | Q38354507 | ||
STAT3 the oncogene - still eluding therapy? | Q38396909 | ||
Phospho flow cytometry methods for the analysis of kinase signaling in cell lines and primary human blood samples | Q39625932 | ||
ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1). | Q39632887 | ||
Effects of STAT3 silencing on fate of chronic myelogenous leukemia K562 cells | Q39701028 | ||
Interleukin-6-induced proliferation of pre-B cells mediated by receptor complexes lacking the SHP2/SOCS3 recruitment sites revisited. | Q40764841 | ||
Establishment of an EBV-positive lymphoblastoid cell line that grows as a lymphoma in nude mice and expresses membrane CD2 molecules | Q41744025 | ||
Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells. | Q42496609 | ||
mTOR signaling regulates the processing of pre-rRNA in human cells | Q42562707 | ||
Pluripotent stem cell models of Shwachman-Diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction | Q42573970 | ||
A novel mouse model provides insights into the neutropenia associated with the ribosomopathy Shwachman-Diamond syndrome | Q43234238 | ||
Analysis of risk factors for myelodysplasias, leukemias and death from infection among patients with congenital neutropenia. Experience of the French Severe Chronic Neutropenia Study Group | Q44657777 | ||
mTOR signaling, function, novel inhibitors, and therapeutic targets. | Q45941008 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 33165 | |
P577 | publication date | 2016-09-23 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes | |
P478 | volume | 6 |
Q40251698 | Advances in research on childhood neutropenia |
Q64078574 | Emerging Role of the Nucleolar Stress Response in Autophagy |
Q47782255 | How Ribosomes Translate Cancer. |
Q47708416 | Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features |
Q58567833 | Shwachman-Diamond Syndrome: Molecular Mechanisms and Current Perspectives |
Q48027760 | The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling. |
Q90162582 | mTOR and STAT3 Pathway Hyper-Activation is Associated with evated Interleukin-6 Levels in Patients with Shwachman-Diamond Syndrome: Further Evidence of Lymphoid Lineage Impairment |
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