scholarly article | Q13442814 |
P50 | author | Christian Kellner | Q51773278 |
P2093 | author name string | Wolfram Klapper | |
Andreas Günther | |||
Philipp Baumann | |||
Martin Gramatzki | |||
Renate Burger | |||
Ralf Schmidmaier | |||
P2860 | cites work | The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and | Q36052399 |
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Bevacizumab attenuates major signaling cascades and eIF4E translation initiation factor in multiple myeloma cells | Q39443134 | ||
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Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone. | Q40569009 | ||
Downstream effectors of oncogenic ras in multiple myeloma cells | Q40679257 | ||
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Immunophenotyping is an independent factor for risk stratification in AML. | Q44419558 | ||
Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies | Q45067792 | ||
Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors | Q45151645 | ||
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Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization. | Q105219584 | ||
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase | Q24300915 | ||
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival | Q24311448 | ||
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A mammalian protein targeted by G1-arresting rapamycin-receptor complex | Q28243712 | ||
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The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins | Q28507365 | ||
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress | Q29614493 | ||
Regulation of translation initiation by FRAP/mTOR | Q29620398 | ||
Exposure-response relationships for everolimus in de novo kidney transplantation: defining a therapeutic range | Q33341797 | ||
A phase 2 study of bortezomib in relapsed, refractory myeloma | Q33348702 | ||
Everolimus in de novo cardiac transplantation: pharmacokinetics, therapeutic range, and influence on cyclosporine exposure | Q33357118 | ||
In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model | Q33362103 | ||
Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma | Q33377526 | ||
Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma | Q33383550 | ||
Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study | Q33394281 | ||
Phase I study of panobinostat plus everolimus in patients with relapsed or refractory lymphoma | Q33410761 | ||
Outcomes in patients with relapsed or refractory multiple myeloma in a phase I study of everolimus in combination with lenalidomide | Q33414827 | ||
Antitumor activity of thalidomide in refractory multiple myeloma | Q33880642 | ||
Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization | Q33920766 | ||
Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients | Q33983816 | ||
Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor. | Q34374071 | ||
Everolimus for advanced pancreatic neuroendocrine tumors. | Q34399809 | ||
Anti-myeloma activity of Akt inhibition is linked to the activation status of PI3K/Akt and MEK/ERK pathway. | Q34490880 | ||
Mammalian TOR: a homeostatic ATP sensor | Q34519173 | ||
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Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors | Q34547487 | ||
Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America | Q34585268 | ||
Defining the role of TORC1/2 in multiple myeloma | Q35631315 | ||
P433 | issue | 4 | |
P304 | page(s) | 541-547 | |
P577 | publication date | 2015-02-14 | |
P1433 | published in | Haematologica | Q5638209 |
P1476 | title | Activity of everolimus (RAD001) in relapsed and/or refractory multiple myeloma: a phase I study | |
P478 | volume | 100 |
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Q28067598 | Everolimus and Malignancy after Solid Organ Transplantation: A Clinical Update |
Q54239708 | Living donor liver transplantation prior to multiple myeloma treatment in a patient with hepatitis B-associated hepatocellular carcinoma and liver cirrhosis: a case report. |
Q92772115 | Metastatic bone disease: Pathogenesis and therapeutic options: Up-date on bone metastasis management |
Q64230046 | NVP-BEZ235-induced autophagy as a potential therapeutic approach for multiple myeloma |
Q41163641 | New insights into the Shwachman-Diamond Syndrome-related haematological disorder: hyper-activation of mTOR and STAT3 in leukocytes. |
Q48263465 | PI3K/AKT/mTOR pathway in multiple myeloma: from basic biology to clinical promise. |
Q88182734 | Protein targeting chimeric molecules specific for bromodomain and extra-terminal motif family proteins are active against pre-clinical models of multiple myeloma |
Q33429430 | TAK-228 (formerly MLN0128), an investigational oral dual TORC1/2 inhibitor: A phase I dose escalation study in patients with relapsed or refractory multiple myeloma, non-Hodgkin lymphoma, or Waldenström's macroglobulinemia |
Q51170783 | The eIF2-alpha kinase HRI is a novel therapeutic target in multiple myeloma. |
Q92052566 | The first-in-human study of the pan-PIM kinase inhibitor PIM447 in patients with relapsed and/or refractory multiple myeloma |
Q47107700 | VS-5584 mediates potent anti-myeloma activity via the upregulation of a class II tumor suppressor gene, RARRES3 and the activation of Bim. |
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