Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains

scientific article published on September 2016

Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.NEURON.2016.08.022
P932PMC publication ID5036532
P698PubMed publication ID27657451

P50authorGabriel SalzmanQ58233075
Sarah D AckermanQ88889663
Chen DingQ91886539
Demet AraçQ92563510
P2093author name stringRong Luo
Akiko Koide
Shohei Koide
Kelly R Monk
Xianhua Piao
Gregory G Tall
Celia G Fernandez
Hannah M Stoveken
Katherine Leon
P2860cites workDisease-associated mutations prevent GPR56-collagen III interactionQ21090961
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Structures of neuroligin-1 and the neuroligin-1/neurexin-1 beta complex reveal specific protein-protein and protein-Ca2+ interactionsQ27649368
Mechanism for adhesion G protein-coupled receptor GPR56-mediated RhoA activation induced by collagen III stimulation.Q35192004
Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonistQ35616282
I want a new drug: G-protein-coupled receptors in drug developmentQ36483932
Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1)Q36573973
Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and MyelinationQ36698095
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Axon-glial signaling and the glial support of axon functionQ37193060
Functional significance of cleavable signal peptides of G protein-coupled receptorsQ37872066
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Allostery and Biased Agonism at Class B G Protein-Coupled ReceptorsQ38796999
Agonistic antibodies reveal the function of GPR56 in human glioma U87-MG cellsQ38891861
Expression and immunoaffinity purification of recombinant soluble human GPR56 protein for the analysis of GPR56 receptor shedding by ELISA.Q38936536
A highly conserved program of neuronal microexons is misregulated in autistic brainsQ39403790
Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2.Q40721631
The adhesion GPCR latrophilin/CIRL shapes mechanosensation.Q40982130
GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2.Q42004258
Compound heterozygosity in GPR56 with bilateral frontoparietal polymicrogyriaQ45113429
The mechanical properties of human angiostatin can be modulated by means of its disulfide bonds: a single-molecule force-spectroscopy study.Q47831541
Splicing variants of the orphan G-protein-coupled receptor GPR56 regulate the activity of transcription factors associated with tumorigenesisQ48541572
New methods to prepare iodinated derivatives by vaporizing iodine labelling (VIL) and hydrogen peroxide VIL (HYPER-VIL)Q82700518
A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domainQ27660385
Teaching an Old Scaffold New Tricks: Monobodies Constructed Using Alternative Surfaces of the FN3 ScaffoldQ27676439
Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domainsQ27679810
Dali server: conservation mapping in 3DQ27860994
Gpr126 functions in Schwann cells to control differentiation and myelination via G-protein activationQ28114956
A tethered agonist within the ectodomain activates the adhesion G protein-coupled receptors GPR126 and GPR133Q28119003
Engineering of recombinant crystallization chaperonesQ28246653
A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesisQ28256067
The adhesion GPCR GPR126 has distinct, domain-dependent functions in Schwann cell development mediated by interaction with laminin-211Q28257321
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptorsQ28257710
A G protein-coupled receptor is essential for Schwann cells to initiate myelinationQ28258127
Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motifQ28262398
Sticky signaling--adhesion class G protein-coupled receptors take the stageQ28291130
Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.Q28507603
FLRT proteins are endogenous latrophilin ligands and regulate excitatory synapse developmentQ28510450
G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and laminationQ28512264
Evolutionarily dynamic alternative splicing of GPR56 regulates regional cerebral cortical patterningQ28513831
GPR56 regulates pial basement membrane integrity and cortical laminationQ28590062
Crystal structures of a double-barrelled fluoride ion channelQ28833651
Mechanisms of alternative splicing regulation: insights from molecular and genomics approachesQ29615084
Multiple sclerosisQ29616022
HorA web server to infer homology between proteins using sequence and structural similarity.Q30376769
Protein foldingQ30415111
GPR56-regulated granule cell adhesion is essential for rostral cerebellar developmentQ30490239
The fibronectin type III domain as a scaffold for novel binding proteinsQ31962422
Evolutionary parameters of the transcribed mammalian genome: an analysis of 2,820 orthologous rodent and human sequencesQ32046333
GPR56-related bilateral frontoparietal polymicrogyria: further evidence for an overlap with the cobblestone complex.Q34142314
LG/LNS domains: multiple functions -- one business end?Q34282459
GPR56 and the developing cerebral cortex: cells, matrix, and neuronal migrationQ34301363
G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophyQ34444447
The adhesion G protein-coupled receptor GPR56 is a cell-autonomous regulator of oligodendrocyte development.Q34458989
The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoAQ34459009
Functional consequences of developmentally regulated alternative splicingQ34632366
Disease-associated mutations affect GPR56 protein trafficking and cell surface expression.Q34638842
Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway.Q34766205
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1292-1304
P577publication date2016-09-01
P1433published inNeuronQ3338676
P1476titleStructural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains
P478volume91

Reverse relations

cites work (P2860)
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