Ciliary neurotrophic factor selectively protects human oligodendrocytes from tumor necrosis factor-mediated injury

scientific article published on February 1996

Ciliary neurotrophic factor selectively protects human oligodendrocytes from tumor necrosis factor-mediated injury is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/(SICI)1097-4547(19960201)43:3<289::AID-JNR4>3.0.CO;2-F
P698PubMed publication ID8714518

P2093author name stringAntel JP
Alinauskas KA
D'Souza SD
P2860cites workPeripheral blood ?-? T cells lyse fresh human brain?Derived oligodendrocytesQ48613619
Morphological changes in oligodendrocytes in the intact mouse optic nerve following intravitreal injection of tumour necrosis factor.Q52514686
Tumor necrosis factor inhibits K+ current expression in cultured oligodendrocytes.Q54286323
Multiple sclerosis: oligodendrocytes in active lesions do not express class II major histocompatibility complex molecules.Q54636938
Natural and induced cytotoxicity of oligodendrocytes by microglia is inhibitable by TGF betaQ67902817
Direct injection of cytokines into the spinal cord causes autoimmune encephalomyelitis-like inflammationQ68382327
Antigen expression by glial cells grown in cultureQ68934518
Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitroQ70392550
Oligodendrocyte lysis by CD4+ T cells independent of tumor necrosis factorQ71613264
Phenotypic and cell cycle properties of human oligodendrocytes in vitroQ72235437
Effects of tumor necrosis factor on inward potassium current and cell morphology in cultured human oligodendrocytesQ72618205
Cell death and control of cell survival in the oligodendrocyte lineageQ34460930
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. UBC MS/MRI Study Group and the IFNB Multiple Sclerosis Study GroupQ34730962
A role for TGF-beta in oligodendrocyte differentiationQ36232939
Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebrosideQ36292898
An antibody to lymphotoxin and tumor necrosis factor prevents transfer of experimental allergic encephalomyelitisQ36353675
The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspectsQ40661193
Multiple sclerosis: immune system molecule expression in the central nervous systemQ40666815
Programmed cell death and the control of cell survival: lessons from the nervous systemQ40777905
Immune and non-immune actions of interferon-beta-Ib on primary human neural cellsQ41351934
Regulation of an oligodendrocyte progenitor cell line by the interleukin-6 family of cytokinesQ41440638
CNTF receptor alpha mRNA expression in rodent cell lines and developing rat.Q41446261
Characteristics of in vitro cytotoxic effects of myelin basic protein-reactive T cell lines on syngeneic oligodendrocytesQ41757496
Immunohistochemical studies of adult human glial cellsQ42505059
CNS glial cells express neurotrophin receptors whose levels are regulated by NGF.Q42507439
Anti?tumor necrosis factor therapy abrogates autoimmune demyelinationQ43924367
Tumour necrosis factor causes an increase in axonal transport of protein and demyelination in the mouse optic nerveQ44635103
Normal rat serum cytotoxicity against syngeneic oligodendrocytes. Complement activation and attack in the absence of anti-myelin antibodies.Q45147036
Cytokines and murine autoimmune encephalomyelitis: inhibition or enhancement of disease with antibodies to select cytokines, or by delivery of exogenous cytokines using a recombinant vaccinia virus systemQ45784536
In vitro evidence for a dual role of tumor necrosis factor‐α in human immunodeficiency virus type 1 encephalopathyQ45786587
CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death.Q46020332
Myelin basic protein content of aggregating rat brain cell cultures treated with cytokines and/or demyelinating antibody: effects of macrophage enrichmentQ46845557
A crucial role for neurotrophin-3 in oligodendrocyte developmentQ48188523
Injury-induced regulation of ciliary neurotrophic factor mRNA in the adult rat brainQ48379221
Recombinant human ciliary neurotrophic factor alters the threshold of hippocampal pyramidal neuron sensitivity to excitotoxin damage: synergistic effects of monosialogangliosidesQ48427373
Mechanisms of oligodendrocyte interaction with normal human serum - defining the role of complementQ48512045
P433issue3
P921main subjectoligodendrocyteQ916698
P304page(s)289-298
P577publication date1996-02-01
P1433published inJournal of Neuroscience ResearchQ6295654
P1476titleCiliary neurotrophic factor selectively protects human oligodendrocytes from tumor necrosis factor-mediated injury
P478volume43

Reverse relations

cites work (P2860)
Q43825678Astrocytes attenuate oligodendrocyte death in vitro through an alpha(6) integrin-laminin-dependent mechanism
Q48706908Astrogliosis in the neonatal and adult murine brain post-trauma: elevation of inflammatory cytokines and the lack of requirement for endogenous interferon-gamma
Q79145512CNTF-activated astrocytes release a soluble trophic activity for oligodendrocyte progenitors
Q40903065Caspases mediate C2-ceramide-induced apoptosis of the human oligodendroglial cell line, MO3.13.
Q48367992Ceramide inhibits inwardly rectifying K+ currents via a Ras- and Raf-1-dependent pathway in cultured oligodendrocytes.
Q48198699Characterization of mature rat oligodendrocytes: a proteomic approach
Q35221952Continued administration of ciliary neurotrophic factor protects mice from inflammatory pathology in experimental autoimmune encephalomyelitis.
Q40762931Cyclic AMP differentiation of the oligodendroglial cell line N20.1 switches staurosporine-induced cell death from necrosis to apoptosis
Q77903811Cytokine actions in the central nervous system
Q44023205Disialoganglioside GD3 is released by microglia and induces oligodendrocyte apoptosis
Q74297214Elevated cerebrospinal fluid level of ciliary neurotrophic factor in acute disseminated encephalomyelitis
Q58425792Endogenous leukemia inhibitory factor production limits autoimmune demyelination and oligodendrocyte loss
Q24337862Gas6/Axl signaling activates the phosphatidylinositol 3-kinase/Akt1 survival pathway to protect oligodendrocytes from tumor necrosis factor alpha-induced apoptosis
Q34398657Glial cells as targets for cytotoxic immune mediators
Q42444225Glial reactivity in ciliary neurotrophic factor-deficient mice after optic nerve lesion.
Q41589718Growth factors and myelin regeneration in multiple sclerosis
Q73109180Interleukin-6 expression in human multiple sclerosis lesions
Q58425803LIF receptor signaling limits immune-mediated demyelination by enhancing oligodendrocyte survival
Q37085783Lame ducks or fierce creatures? The role of oligodendrocytes in multiple sclerosis
Q49059546Lipopolysaccharide administration in vivo induces differential expression of cAMP-specific phosphodiesterase 4B mRNA splice variants in the mouse brain.
Q41712461Macrophages in CNS remyelination: friend or foe?
Q37625399Molecular features of neural stem cells enable their enrichment using pharmacological inhibitors of survival-promoting kinases
Q36377383Multiple sclerosis: Fas signaling in oligodendrocyte cell death
Q60684621Nerve Growth Factor Protects Oligodendrocytes from Tumor Necrosis Factor-α-induced Injury through Akt-mediated Signaling Mechanisms
Q36166488Neural stem cells in inflammatory CNS diseases: mechanisms and therapy.
Q47892533Neurotrophin-3 and brain-derived neurotrophic factor induce oligodendrocyte proliferation and myelination of regenerating axons in the contused adult rat spinal cord.
Q30355283Nudging oligodendrocyte intrinsic signaling to remyelinate and repair: Estrogen receptor ligand effects.
Q48510916Oligodendrocytes from forebrain are highly vulnerable to AMPA/kainate receptor-mediated excitotoxicity
Q33671711Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury.
Q77421414Photoreceptor rescue
Q47841614Puma, but not noxa is essential for oligodendroglial cell death
Q31910504Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes
Q51321537Sex-related differences of cAMP-specific PDE4B3 mRNA in oligodendrocytes following systemic inflammation.
Q41841345Signal transduction of stress via ceramide
Q48635220Target depletion of distinct tumor necrosis factor receptor subtypes reveals hippocampal neuron death and survival through different signal transduction pathways.
Q36571196The pathophysiology of ischemic injury to developing white matter
Q35180002The role of the JAK-STAT pathway in neural stem cells, neural progenitor cells and reactive astrocytes after spinal cord injury
Q74587444Understanding glial abnormalities associated with myelin deficiency in the jimpy mutant mouse

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