review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0165-0173(97)00055-6 |
P698 | PubMed publication ID | 9600623 |
P50 | author | Bernardo Castellano | Q37843102 |
José Miguel Vela | Q56947146 | ||
Berta González | Q59564318 | ||
P2860 | cites work | Myelin Basic Protein Deposition in the Optic and Sciatic Nerves of Dysmyelinating Mutants Quaking, Jimpy, Trembler, MLD, and Shiverer During Development | Q72712550 |
Biochemical Expression of Mosaicism in Female Mice Heterozygous for the Jimpy Gene | Q72723128 | ||
Assembly of CNS myelin in the absence of proteolipid protein | Q73016640 | ||
Abnormal expression of the proliferating cell nuclear antigen (PCNA) in the spinal cord of the hypomyelinated Jimpy mutant mice | Q73093917 | ||
Jimpy, a new totally sex-linked gene in the house mouse | Q78609651 | ||
Hypomyelination and recovery of the myelin deficit in heterozygous jimpy mice | Q87976727 | ||
Myelination in the jimpy mouse in the absence of proteolipid protein | Q93513727 | ||
Rumpshaker mouse: a new X-linked mutation affecting myelination: evidence for a defect in PLP expression | Q28511941 | ||
MUTANT MICE (QUAKING AND JIMPY) WITH DEFICIENT MYELINATION IN THE CENTRAL NERVOUS SYSTEM | Q28590426 | ||
Dominant-negative action of the jimpy mutation in mice complemented with an autosomal transgene for myelin proteolipid protein | Q34334046 | ||
Aberrant splicing of proteolipid protein mRNA in the dysmyelinating jimpy mutant mouse | Q34603372 | ||
Macrophages and microglia in the nervous system | Q34660547 | ||
Oligodendroglial cell death induced by oxygen radicals and its protection by catalase | Q34853603 | ||
Morphology of demyelination in the human central nervous system | Q35513515 | ||
The role of macrophages in demyelination | Q35513547 | ||
Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice | Q35931734 | ||
Inflammatory cytokines within the central nervous system: sources, function, and mechanism of action | Q36347725 | ||
Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis. | Q36437643 | ||
Jimpy mutant mouse: a 74-base deletion in the mRNA for myelin proteolipid protein and evidence for a primary defect in RNA splicing | Q36458669 | ||
Structure and Function of Myelin Protein Genes | Q36649406 | ||
The pH of jimpy glia is increased: intracellular measurements using fluorescent laser cytometry | Q36764700 | ||
Microglial cell reaction in the gray and white matter in spinal cords from jimpy mice. An enzyme histochemical study at the light and electron microscope level | Q36839371 | ||
Molecular biology of myelin proteins from the central nervous system | Q38189000 | ||
Refined genetic mapping and proteolipid protein mutation analysis in X-linked pure hereditary spastic paraplegia | Q38929854 | ||
Cellular and molecular aspects of myelin protein gene expression | Q39581704 | ||
Contribution of transplantations to the understanding of the role of the PLP gene | Q40395804 | ||
Immunocytochemical investigations of murine leukodystrophies. A study of the mutants 'jimpy' (jp) and 'myelin deficient' (mld). | Q48795511 | ||
Effects of colony stimulating factors on isolated microglia in vitro | Q48846984 | ||
GFAP immunoreactivity reveals astrogliosis in females heterozygous for jimpy | Q48882804 | ||
Increased proliferation of oligodendrocytes in the hypomyelinated mouse mutant-jimpy | Q48895293 | ||
The fine structure of the cerebella of jimpy mice and their "normal" litter mates | Q49012729 | ||
Quaking*jimpy double mutant mice: additional evidence for independence of primary deficits in jimpy | Q49049451 | ||
The microglial reaction in spinal cords of jimpy mice is related to apoptotic oligodendrocytes. | Q49060147 | ||
Activation and proliferation of the isolated microglia by colony stimulating factor-1 and possible involvement of protein kinase C. | Q49101442 | ||
Selective degeneration of oligodendrocytes mediated by reactive oxygen species. | Q50884032 | ||
Abnormal glial maturation in the white matter in Jimpy mice. An optical study. | Q51108049 | ||
Mutations in the myelin proteolipid protein gene alter oligodendrocyte gene expression in jimpy and jimpymsd mice. | Q52054165 | ||
A case of Pelizaeus-Merzbacher disease showing increased dosage of the proteolipid protein gene. | Q52209396 | ||
Jimpy mutation affects astrocytes: lengthening of the cell cycle in vitro. | Q52228368 | ||
[Ultrastructural study of the corpus callosum in Jimpy mice]. | Q54096881 | ||
Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene | Q57043289 | ||
Expression of macrophage colony-stimulating factor gene in the mouse brain during development | Q57267765 | ||
Myelin deficit in the Jimpy mouse may be due to cellular abnormalities in astroglia | Q59086257 | ||
Oligodendrocyte development and differentiation in the rumpshaker mutation | Q59782506 | ||
Stimulation of in vitro myelin synthesis by microglia | Q60641821 | ||
Paralytic tremor (pt) rabbit: a sex-linked mutation affecting proteolipid protein-gene expression | Q62035802 | ||
Conservative amino acid substitution in the myelin proteolipid protein of jimpymsd mice | Q67653573 | ||
Natural and induced cytotoxicity of oligodendrocytes by microglia is inhibitable by TGF beta | Q67902817 | ||
Macromolecular structure of axonal membrane in the optic nerve of the jimpy mouse | Q67934282 | ||
Expression of galactocerebroside in developing normal and jimpy oligodendrocytes in situ | Q67971685 | ||
Cell kinetics and cell death in the optic nerve of the myelin deficient rat | Q68002740 | ||
Astroglial plasticity in hemizygous and heterozygous jimpy mice | Q68009693 | ||
Arrest of proteolipid transport through the Golgi apparatus in Jimpy brain | Q68182648 | ||
Differences in levels of neuroglial cell death in jimpy male mice and carrier females | Q68841619 | ||
[Quantitative study of myelination and axonal growth in corpus callosum and posterior columns of spinal cord in the Jimpy mouse (author's transl)] | Q68867924 | ||
Glial fibrillary acidic protein in mutant mice with deficiency of myelination: Quaking and jimpy | Q69360883 | ||
Oligodendroglial cell death in jimpy mice: an explanation for the myelin deficit | Q69622249 | ||
Expression of the jimpy gene in the spinal cords of heterozygous female mice. 2. Oligodendroglial and endothelial cell hyperplasia | Q69637327 | ||
Dysmyelination in "jimpy" mouse. Electron microscopic study | Q69782011 | ||
Oligodendroglial structures and distribution shown by carbonic anhydrase immunostaining in the spinal cords of developing normal and shiverer mice | Q69969966 | ||
Colony-stimulating factors as promoters of ameboid microglia | Q70229709 | ||
Tumor necrosis factor mediates myelin and oligodendrocyte damage in vitro | Q70392550 | ||
Accumulation of GFA, the monomeric precursor of the gliofilaments, during development in normal mice and dysmyelinating mutants | Q70655680 | ||
Shaking pups: a disorder of central myelination in the Spaniel dog. Part 1. Clinical, genetic and light-microscopical observations | Q70666322 | ||
Expression of mosaicism in females heterozygous for Jimpy | Q70755463 | ||
Neuropathology and genetics of Pelizaeus-Merzbacher disease | Q70785121 | ||
Programmed cell death in the dysmyelinating mutants | Q70785128 | ||
Fine structure of the central myelin sheath in the myelin deficient mutant Shiverer mouse, with special reference to the pattern of myelin formation by oligodendroglia | Q70866299 | ||
Radioautographic evidence for the protracted proliferation of glial cells in the central nervous system of jimpy mice | Q70937395 | ||
Isolation and characterization of defective jimpy oligodendrocytes in culture | Q70938835 | ||
Oligodendroglial precursor cell susceptibility to hypoxia is related to poor ability to cope with reactive oxygen species | Q70951131 | ||
Abnormal cell relationships in Jimpy mice: electron microscopic and immunocytochemical findings | Q71106623 | ||
Abnormal metabolic response to excess potassium in astrocytes from the Jimpy mouse, a convulsing neurological mutant | Q71128922 | ||
Hypomyelinated mutant mice: description of jpmsd and comparison with jp and qk on their present genetic backgrounds | Q71235075 | ||
Hypomyelinated mutant mice. III. Increased myelination in mutant cerebellum co-cultured with normal optic nerve | Q71507120 | ||
Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development | Q71543637 | ||
Epigenetic factors up-regulate expression of myelin proteins in the dysmyelinating jimpy mutant mouse | Q71567360 | ||
Myelin structure in proteolipid protein (PLP)-null mouse spinal cord | Q71603477 | ||
A combination of PLP and DM20 transgenes promotes partial myelination in the jimpy mouse | Q71638166 | ||
Isolation and identification of proteolipid proteins in jimpy mouse brain | Q71664227 | ||
Adhesive properties of proteolipid protein are responsible for the compaction of CNS myelin sheaths | Q71706053 | ||
Overexpression of DM20 messenger RNA in two brothers with Pelizaeus-Merzbacher disease | Q71778448 | ||
Evidence that some oligodendrocyte progenitors in the developing optic pathway express the plp gene | Q71914971 | ||
Apoptosis occurs in the oligodendroglial lineage, and is prevented by basic fibroblast growth factor | Q72225206 | ||
Expression of cytokines during glial differentiation | Q72368141 | ||
Immunohistochemical localization of the myelin basic protein and of the glial fibrillary acidic protein: Comparative study in normal, quaking and jimpy mice | Q72622821 | ||
Cytokines in cerebral ischemia: expression of transforming growth factor beta-1 (TGF-beta 1) mRNA in the postischemic adult rat hippocampus | Q72643380 | ||
Regional distribution of myelin basic protein in the central nervous system of quaking, jimpy, and normal mice during development and aging | Q72650189 | ||
Genetics of Pelizaeus-Merzbacher disease | Q40397095 | ||
Cell-mediated cytotoxicity: contact and secreted factors | Q40488888 | ||
Neurological mouse mutants and the genes of myelin | Q40561097 | ||
Cytotoxicity of microglia | Q40870381 | ||
Oxygen free radicals and metallothionein | Q40889930 | ||
Transgenic systems in studying myelin gene expression | Q40939826 | ||
Temperature-dependent regulation of PLP/DM20 and CNP gene expression in two conditionally-immortalized jimpy oligodendrocyte cell lines | Q41118714 | ||
Regulation of oligodendrocyte development and CNS myelination by growth factors: prospects for therapy of demyelinating disease | Q41157691 | ||
Ciliary neurotrophic factor selectively protects human oligodendrocytes from tumor necrosis factor-mediated injury | Q41232387 | ||
Jimpy mouse myelin revisited with freeze-fracture | Q41433616 | ||
Regulation of an oligodendrocyte progenitor cell line by the interleukin-6 family of cytokines | Q41440638 | ||
Many naturally occurring mutations of myelin proteolipid protein impair its intracellular transport. | Q41478756 | ||
Brain peptides and glial growth. I. Glia-promoting factors as regulators of gliogenesis in the developing and injured central nervous system | Q41500473 | ||
Effect of the Jimpy Mutation on Expression of Myelin Proteins in Heterozygous and Hemizygous Mouse Brain | Q41545300 | ||
Neurons and astrocytes influence the development of purified O-2A progenitor cells | Q41704584 | ||
Fibronectin and laminin regulate the in vitro differentiation of microglial cells | Q41966365 | ||
Myelin proteolipid protein gene structure and its regulation of expression in normal and jimpy mutant mice | Q42638631 | ||
Myelin basic protein is affected by reduced synthesis of myelin proteolipid protein in the jimpy mouse | Q42794199 | ||
Immunohistochemical studies on cross-transplantations between jimpy, shiverer, and normal newborn mice | Q43514731 | ||
Uncoupling of hypomyelination and glial cell death by a mutation in the proteolipid protein gene | Q43605216 | ||
Gene expression in the jimpy mutant: evidence for fewer oligodendrocytes expressing myelin protein genes and impaired translocation of myelin basic protein mRNA. | Q43768343 | ||
Death of individual oligodendrocytes in jimpy brain precedes expression of proteolipid protein | Q44063104 | ||
Myelin proteolipid protein gene expression in jimpy and jimpy(msd) mice | Q44286193 | ||
Oligodendroglial cell development in jimpy mice and controls. An electron-microscopic study in the optic nerve | Q44306073 | ||
Glial conditioned medium enables jimpy oligodendrocytes to express properties of normal oligodendrocytes: production of myelin antigens and membranes | Q44489386 | ||
Tumour necrosis factor causes an increase in axonal transport of protein and demyelination in the mouse optic nerve | Q44635103 | ||
Developmental expression of glial fibrillary acidic protein and glutamine synthetase mRNAs in normal and jimpy mice | Q44914504 | ||
Oligodendrocytes of the jimpy phenotype can be partially restored by environmental factors in vivo | Q45132323 | ||
Comparative immunocytochemistry of Pelizaeus-Merzbacher disease, the jimpy mouse, and the myelin-deficient rat. | Q46014404 | ||
CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death. | Q46020332 | ||
Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage | Q46440780 | ||
Paralytic tremor (pt): a new allele of the proteolipid protein gene in rabbits. | Q48077825 | ||
Fate of jimpy-type oligodendrocytes in jimpy heterozygote. | Q48137303 | ||
The ontogeny of ultrasonic vocalizations and other behaviors in male jimpy (jp/Y) mice and their normal male littermates | Q48160340 | ||
A defect in the cell cycle of neuroglia in the myelin deficient jimpy mouse | Q48197121 | ||
Developmental expression of the myelin proteolipid protein and basic protein mRNAs in normal and dysmyelinating mutant mice | Q48204702 | ||
Neuronal abnormalities associated with impaired myelination during brain development: a golgi study of neocortex in the Jimpy mouse | Q48212983 | ||
Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells | Q48215877 | ||
The fifth exon of the myelin proteolipid protein-coding gene is not utilized in the brain of jimpy mutant mice | Q48262095 | ||
Biochemical correlates of myelination in brain and spinal cord of mice heterozygous for the jimpy gene | Q48274896 | ||
Expression of the jimpy gene in the spinal cords of heterozygous female mice. I. An early myelin deficit followed by compensation | Q48292872 | ||
Appearance of hematogenous cells in the white matter of myelin-deficient Jimpy mice. | Q48312242 | ||
Jimpy mice: quantitation of myelin-associated glycoprotein and other proteins | Q48331187 | ||
The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy mice | Q48334404 | ||
A single nucleotide difference in the gene for myelin proteolipid protein defines the jimpy mutation in mouse | Q48334787 | ||
An AG----GG transition at a splice site in the myelin proteolipid protein gene in jimpy mice results in the removal of an exon | Q48335699 | ||
Shiverer jimpy double mutant mice. II. Morphological evidence supports reciprocal intergenic suppression | Q48342788 | ||
Shiverer jimpy double mutant mice. I. Biochemical evidence for reciprocal intergenic suppression | Q48342960 | ||
Regional and developmental variations of GFAP and actin mRNA levels in the CNS of jimpy and shiverer mutant mice | Q48382385 | ||
Expression of myelin proteolipid protein and basic protein in normal and dysmyelinating mutant mice | Q48384472 | ||
Characterization of interleukin-1 production by microglia in culture | Q48430990 | ||
Selective expression of DM-20, an alternatively spliced myelin proteolipid protein gene product, in developing nervous system and in nonglial cells | Q48476911 | ||
DM-20 mRNA Is Expressed During the Embryonic Development of the Nervous System of the Mouse | Q48511250 | ||
Rumpshaker: an X-linked mutation causing hypomyelination: developmental differences in myelination and glial cells between the optic nerve and spinal cord | Q48589841 | ||
Induction of metallothionein in astrocytes and microglia in the spinal cord from the myelin-deficient jimpy mouse | Q48595546 | ||
Detection of interleukin-1 and interleukin-6 in adult rat brain, following mechanical injury, by in vivo microdialysis: evidence of a role for microglia in cytokine production | Q48661807 | ||
Developmental expression of myelin protein genes in dysmyelinating mutant mice: analysis by nuclear run-off transcription assay, in situ hybridization, and immunohistochemistry | Q48789070 | ||
Myelination of jp,jpmsd, and qk axons by normal glia in vitro: ultrastructural and autoradiographic evidence | Q48795322 | ||
P433 | issue | 1 | |
P304 | page(s) | 29-42 | |
P577 | publication date | 1998-03-01 | |
P1476 | title | Understanding glial abnormalities associated with myelin deficiency in the jimpy mutant mouse | |
P478 | volume | 26 |
Q48233658 | Alterations of myelin proteins in inflammatory demyelination of BALB/c mice caused by Angiostrongylus cantonensis |
Q48448864 | Cannabinoids promote oligodendrocyte progenitor survival: involvement of cannabinoid receptors and phosphatidylinositol-3 kinase/Akt signaling. |
Q33932929 | Cellular compensatory mechanisms in the CNS of dysmyelinated rats |
Q34013147 | Developing nodes of Ranvier are defined by ankyrin-G clustering and are independent of paranodal axoglial adhesion |
Q50585294 | Effects of the jimpy mutation on mouse retinal structure and function. |
Q37312220 | General control nonderepressible 2 (GCN2) kinase protects oligodendrocytes and white matter during branched-chain amino acid deficiency in mice |
Q34313677 | Re-establishing the regenerative potential of central nervous system axons in postnatal mice |
Q42036358 | Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids |
Q48302520 | Severe Convulsions and Dysmyelination in Both Jimpy and Cx32/47 -/- Mice may Associate Astrocytic L-Channel Function with Myelination and Oligodendrocytic Connexins with Internodal Kv Channels |
Q36325659 | Survival of, and competition between, oligodendrocytes expressing different alleles of the Plp gene. |
Q28505398 | Teneurin-4 is a novel regulator of oligodendrocyte differentiation and myelination of small-diameter axons in the CNS |
Q33951997 | The midline glia of Drosophila: a molecular genetic model for the developmental functions of glia. |
Q35550991 | The unfolded protein response in protein aggregating diseases. |
Q30482400 | Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders. |