Induction of metallothionein in astrocytes and microglia in the spinal cord from the myelin-deficient jimpy mouse

scientific article published in September 1997

Induction of metallothionein in astrocytes and microglia in the spinal cord from the myelin-deficient jimpy mouse is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-8993(97)00628-8
P698PubMed publication ID9367267

P50authorJuan HidalgoQ37379782
Bernardo CastellanoQ37843102
P2093author name stringGonzález B
Vela JM
P2860cites workThe growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like proteinQ24336853
MT-III, a brain-specific member of the metallothionein gene familyQ24564603
Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epitheliaQ28505694
Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxideQ34334574
Macrophages and microglia in the nervous systemQ34660547
Inflammatory cytokines within the central nervous system: sources, function, and mechanism of actionQ36347725
The pH of jimpy glia is increased: intracellular measurements using fluorescent laser cytometryQ36764700
Microglial cell reaction in the gray and white matter in spinal cords from jimpy mice. An enzyme histochemical study at the light and electron microscope levelQ36839371
MetallothioneinQ39740491
Immunochemical detection of metallothionein in brainQ40471251
Induction of metallothionein in astrocytes by cytokines and heavy metalsQ40588773
Cytokine receptors on glial cellsQ40633467
Oxygen free radicals and metallothioneinQ40889930
Immunocytochemical method to identify basic protein in myelin-forming oligodendrocytes of newborn rat C.N.SQ40891446
Activation of human monocytes with lipopolysaccharide induces metallothionein expression and is diminished by zincQ41496402
Metallothionein protects DNA from oxidative damageQ41563499
Effects of CdCl2 and Cd-metallothionein on cultured mesangial cellsQ41603957
Metallothionein immunoreactivity is increased in the spinal cord of patients with amyotrophic lateral sclerosisQ41934794
In Vivo Expression of Metallothionein in Rat Alveolar Macrophages and Type II Epithelial Cells Following Repeated Cadmium Aerosol ExposuresQ42276822
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brainQ42477525
Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genesQ42490264
Glial conditioned medium enables jimpy oligodendrocytes to express properties of normal oligodendrocytes: production of myelin antigens and membranesQ44489386
Localization of metallothionein in the brain of rat and mouseQ44809476
Developmental expression of glial fibrillary acidic protein and glutamine synthetase mRNAs in normal and jimpy miceQ44914504
Distribution of zinc metallothionein I mRNA in rat brain using in situ hybridization.Q48111543
A defect in the cell cycle of neuroglia in the myelin deficient jimpy mouseQ48197121
Distribution of metallothionein in the human central nervous systemQ48287921
Jimpy mice: quantitation of myelin-associated glycoprotein and other proteinsQ48331187
The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy miceQ48334404
Identification and distribution of microglial cells in the cerebral cortex of the lizard: a histochemical studyQ48655471
Localization of the glial fibrillary acidic protein in astrocytes by immunofluorescenceQ48735182
Glial immunoreactivity for metallothionein in the rat brainQ48820458
Increased proliferation of oligodendrocytes in the hypomyelinated mouse mutant-jimpyQ48895293
The microglial reaction in spinal cords of jimpy mice is related to apoptotic oligodendrocytes.Q49060147
Jimpy mutation affects astrocytes: lengthening of the cell cycle in vitro.Q52228368
Disruption of the blood-brain interface in neonatal rat neocortex induces a transient expression of metallothionein in reactive astrocytes.Q52510591
Effect of zinc, copper and glucocorticoids on metallothionein levels of cultured neurons and astrocytes from rat brainQ58028090
Myelin deficit in the Jimpy mouse may be due to cellular abnormalities in astrogliaQ59086257
Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitroQ64389561
Increase in metallothionein produced by chemicals that induce oxidative stressQ67972792
Astroglial plasticity in hemizygous and heterozygous jimpy miceQ68009693
Distribution of cadmium chloride and cadmium-metallothionein to liver parenchymal, Kupffer, and endothelial cells: their relative ability to express metallothioneinQ68062621
Oligodendroglial cell death in jimpy mice: an explanation for the myelin deficitQ69622249
Morphology and distribution of microglial cells in the young and adult mouse cerebellumQ70938073
Abnormal metabolic response to excess potassium in astrocytes from the Jimpy mouse, a convulsing neurological mutantQ71128922
Receptor-mediated phagocytosis of myelin by macrophages and microglia: effect of opsonization and receptor blocking agentsQ71333274
Modulation of human microglial cell superoxide production by cytokinesQ71894196
Cadmium chloride (CdCl2)-induced metallothionein (MT) expression in neonatal rat primary astrocyte culturesQ71914564
Neuronal localization of metallothioneins in rat and human spinal cordQ72010767
Demonstration of poly-N-acetyl lactosamine residues in ameboid and ramified microglial cells in rat brain by tomato lectin bindingQ72051474
Accumulation of metallothionein and its multiple forms by zinc, cadmium and dexamethasone in human peripheral T and B lymphocytes and monocytesQ72407393
Differential induction of metallothionein synthesis by interleukin-6 and tumor necrosis factor-alpha in rat tissuesQ72416984
Regulation of metallothionein-I+II levels in specific brain areas and liver in the rat: role of catecholaminesQ72573524
Constitutive expression of metallothionein genes in mouse brainQ72601027
Development of a competitive double antibody radioimmunoassay for rat metallothioneinQ72740301
Abnormal expression of the proliferating cell nuclear antigen (PCNA) in the spinal cord of the hypomyelinated Jimpy mutant miceQ73093917
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectastrocyteQ502961
microgliaQ1622829
P304page(s)345-355
P577publication date1997-09-01
P1433published inBrain ResearchQ4955782
P1476titleInduction of metallothionein in astrocytes and microglia in the spinal cord from the myelin-deficient jimpy mouse
P478volume767

Reverse relations

cites work (P2860)
Q48257398CNS wound healing is severely depressed in metallothionein I- and II-deficient mice.
Q58027841Differential expression of metallothioneins in the CNS of mice with experimental autoimmune encephalomyelitis
Q30489096Doxycycline treatment decreases morbidity and mortality of murine neurocysticercosis: evidence for reduction of apoptosis and matrix metalloproteinase activity
Q58027881Effect of dietary zinc deficiency on brain metallothionein-I and -III mRNA levels during stress and inflammation
Q48666444Metallothionein expression and oxidative stress in the brain
Q37903764Neuroprotection and regeneration by extracellular metallothionein via lipoprotein-receptor-related proteins.
Q48149949Primary cortical glial reaction versus secondary thalamic glial response in the excitotoxically injured young brain: astroglial response and metallothionein expression
Q48305181Role of metallothionein-III following central nervous system damage
Q36835575Role of zinc in ALS.
Q34317904Roles of the metallothionein family of proteins in the central nervous system
Q74587444Understanding glial abnormalities associated with myelin deficiency in the jimpy mutant mouse

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