Differential expression of metallothioneins in the CNS of mice with experimental autoimmune encephalomyelitis

scientific article published on 01 January 2001

Differential expression of metallothioneins in the CNS of mice with experimental autoimmune encephalomyelitis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0306-4522(01)00252-4
P698PubMed publication ID11530242

P50authorMilena PenkowaQ3378367
Carmen EspejoQ55314076
Juan HidalgoQ37379782
Eva Martínez-CáceresQ50280630
P2093author name stringA Garcia
J Carrasco
I Sáez-Torres
P2860cites workThe growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like proteinQ24336853
MT-III, a brain-specific member of the metallothionein gene familyQ24564603
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Implantation of stimulated homologous macrophages results in partial recovery of paraplegic rats.Q55067631
Bioactivity of Metallothionein-3 Correlates with Its Novel .beta. Domain Sequence Rather Than Metal Binding PropertiesQ58838699
Possible role for metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicalsQ60786744
Immune response in mice that lack the interferon-gamma receptorQ62022366
A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H-2b mice: fine specificity and T cell receptor V beta expression of encephalitogenic T cellsQ71918597
Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitisQ71941640
Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental allergic encephalomyelitisQ73128576
Ectopic expression of metallothionein-III causes pancreatic acinar cell necrosis in transgenic miceQ74180593
Mice with an inactivation of the inducible nitric oxide synthase gene are susceptible to experimental autoimmune encephalomyelitisQ74494545
Changes in brain gene expression shared by scrapie and Alzheimer diseaseQ24607265
Uric acid, a natural scavenger of peroxynitrite, in experimental allergic encephalomyelitis and multiple sclerosisQ24670394
Induction of a new metallothionein isoform (MT-IV) occurs during differentiation of stratified squamous epitheliaQ28505694
Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.Q34153407
Local nitric oxide production in viral and autoimmune diseases of the central nervous systemQ34209628
Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxideQ34334574
Immunological aspects of demyelinating diseasesQ35319665
Nitric oxide localized to spinal cords of mice with experimental allergic encephalomyelitis: an electron paramagnetic resonance studyQ36362030
Evidence for a protective role of metallothionein-1 in focal cerebral ischemiaQ36561063
Coordinate regulation of mouse metallothionein I and II genes by heavy metals and glucocorticoidsQ36885395
Expression and regulation of brain metallothioneinQ40471240
Astrocyte metallothioneins (MTs) and their neuroprotective roleQ40877767
Oxygen free radicals and metallothioneinQ40889930
Constitutive expression of metallothionein-III (MT-III), but not MT-I, inhibits growth when cells become zinc deficientQ41279563
Metallothioneins in brain--the role in physiology and pathology.Q41384333
Metallothionein immunoreactivity is increased in the spinal cord of patients with amyotrophic lateral sclerosisQ41934794
Temporalspatial patterns of expression of metallothionein-I and -III and other stress related genes in rat brain after kainic acid-induced seizuresQ42277605
The effects of 6-hydroxydopamine and oxidative stress on the level of brain metallothioneinQ42287223
Localization of metallothionein-I and -III expression in the CNS of transgenic mice with astrocyte-targeted expression of interleukin 6.Q42462809
Chemical modulation of metallothionein I and III mRNA in mouse brainQ42482048
Enhanced sensitivity to oxidative stress in cultured embryonic cells from transgenic mice deficient in metallothionein I and II genesQ42490264
Effect of stress on mouse and rat brain metallothionein I and III mRNA levels.Q42528704
Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: a neuroprotective role of inflammation?Q42943930
Gene targeting in normal somatic cells: inactivation of the interferon-gamma receptor in myoblastsQ45872568
Aggravation of experimental allergic encephalomyelitis (EAE) by administration of nitric oxide (NO) synthase inhibitorsQ46388109
Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein-III (GIF).Q48103518
Primary cortical glial reaction versus secondary thalamic glial response in the excitotoxically injured young brain: astroglial response and metallothionein expressionQ48149949
Expression of growth inhibitory factor (metallothionein-III) mRNA and protein following excitotoxic immature brain injuryQ48226784
Impaired inflammatory response to glial cell death in genetically metallothionein-I- and -II-deficient miceQ48245297
Effect of nitric oxide synthesis inhibition on mouse liver and brain metallothionein expressionQ48251392
Oxidative damage to DNA in plaques of MS brainsQ48336747
Expression of interleukin (IL)-1 beta, IL-6 and their respective receptors in the normal rat brain and after injuryQ48413747
Endotoxin and intracerebroventricular injection of IL-1 and IL-6 induce rat brain metallothionein-I and -II.Q48465090
Increased astrocytic expression of metallothioneins I + II in brainstem of adult rats treated with 6-aminonicotinamideQ48549874
Induction of metallothionein in astrocytes and microglia in the spinal cord from the myelin-deficient jimpy mouseQ48595546
Transgenic expression of interleukin 6 in the central nervous system regulates brain metallothionein-I and -III expression in miceQ48640156
Liver, brain, and heart metallothionein induction by stressQ48891428
Disruption of the blood-brain interface in neonatal rat neocortex induces a transient expression of metallothionein in reactive astrocytes.Q52510591
Metallothionein (MT)-III: generation of polyclonal antibodies, comparison with MT-I+II in the freeze lesioned rat brain and in a bioassay with astrocytes, and analysis of Alzheimer's disease brains.Q53338345
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectexperimental autoimmune encephalomyelitisQ494066
P1104number of pages11
P304page(s)1055-1065
P577publication date2001-01-01
P1433published inNeuroscienceQ15708571
P1476titleDifferential expression of metallothioneins in the CNS of mice with experimental autoimmune encephalomyelitis
P478volume105

Reverse relations

cites work (P2860)
Q43755784Altered inflammatory response and increased neurodegeneration in metallothionein I+II deficient mice during experimental autoimmune encephalomyelitis.
Q44893711Anti-myelin antibodies play an important role in the susceptibility to develop proteolipid protein-induced experimental autoimmune encephalomyelitis.
Q48532399Changes of metallothionein 1 and 3 mRNA levels with age in brain of senescence-accelerated mice and the effects of acupuncture.
Q40167890Clinical and Histopathological Amelioration of Experimental Autoimmune Encephalomyelitis by AAV Vectors Expressing a Soluble Interleukin-23 Receptor.
Q42527596Immune response gene expression increases in the aging murine hippocampus.
Q36695714Inflammation, demyelination, neurodegeneration and neuroprotection in the pathogenesis of multiple sclerosis
Q46514027Involvement of neuropsin in the pathogenesis of experimental autoimmune encephalomyelitis
Q35501612Lack of association between autism and four heavy metal regulatory genes
Q37890288Metallothionein and brain inflammation
Q41984348Metallothioneins and brain injury: What transgenic mice tell us.
Q44485595Metallothioneins: Emerging Modulators in Immunity and Infection.
Q44829975Myeloid-derived suppressor cells are generated during retroviral transduction of murine bone marrow.
Q28265790Neurotoxic effects of postnatal thimerosal are mouse strain dependent
Q39313856Semaphorin 7A as a Potential Therapeutic Target for Multiple Sclerosis
Q33416725Tolerance induction in experimental autoimmune encephalomyelitis using non-myeloablative hematopoietic gene therapy with autoantigen

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