The Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host

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The Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.00025-15
P932PMC publication ID4468532
P698PubMed publication ID25895966
P5875ResearchGate publication ID275278730

P50authorStuart E TurveyQ45358108
Matthew A CroxenQ56491447
Hong YangQ57164247
P2093author name stringB Brett Finlay
Martin Stahl
Hongbing Yu
Bruce A Vallance
Kirandeep Bhullar
Maryam Zarepour
P2860cites workBacterial serine proteases secreted by the autotransporter pathway: classification, specificity, and role in virulenceQ26828625
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Critical role of T cell-dependent serum antibody, but not the gut-associated lymphoid tissue, for surviving acute mucosal infection with Citrobacter rodentium, an attaching and effacing pathogenQ28589275
The serine protease motif of Pic mediates a dose-dependent mucolytic activity after binding to sugar constituents of the mucin substrateQ38290252
Production of cellulose and curli fimbriae by members of the family Enterobacteriaceae isolated from the human gastrointestinal tractQ39776937
Enteropathogenic Escherichia coli protein secretion is induced in response to conditions similar to those in the gastrointestinal tract.Q39830323
The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cellsQ40231712
CsgA is a pathogen-associated molecular pattern of Salmonella enterica serotype Typhimurium that is recognized by Toll-like receptor 2.Q40373243
The TibA adhesin/invasin from enterotoxigenic Escherichia coli is self recognizing and induces bacterial aggregation and biofilm formationQ42727339
Citrobacter rodentium translocated intimin receptor (Tir) is an essential virulence factor needed for actin condensation, intestinal colonization and colonic hyperplasia in miceQ44375935
PicU, a second serine protease autotransporter of uropathogenic Escherichia coliQ44735528
A set of recombineering plasmids for gram-negative bacteriaQ50080127
Expression of cellulose and curli fimbriae by Escherichia coli isolated from the gastrointestinal tractQ50085741
OmpA influences Escherichia coli biofilm formation by repressing cellulose production through the CpxRA two-component system.Q52594649
Antigen 43, a phase-variable bipartite outer membrane protein, determines colony morphology and autoaggregation in Escherichia coli K-12.Q54568586
Host-Mediated Inflammation Disrupts the Intestinal Microbiota and Promotes the Overgrowth of EnterobacteriaceaeQ57932930
Toll-like receptor 2 plays a critical role in maintaining mucosal integrity during Citrobacter rodentium-induced colitisQ58061375
Gene disruption in Escherichia coli: TcR and KmR cassettes with the option of Flp-catalyzed excision of the antibiotic-resistance determinantQ29615039
Independent and tight regulation of transcriptional units in Escherichia coli via the LacR/O, the TetR/O and AraC/I1-I2 regulatory elementsQ29615996
Autotransporter genes pic and tsh are associated with Escherichia coli strains that cause acute pyelonephritis and are expressed during urinary tract infectionQ30164331
Role of class 1 serine protease autotransporter in the pathogenesis of Citrobacter rodentium colitisQ30409278
Broad spectrum activity of a lectin-like bacterial serine protease family on human leukocytesQ30410326
Serine protease autotransporters from Shigella flexneri and pathogenic Escherichia coli target a broad range of leukocyte glycoproteinsQ30431075
Antigen 43 facilitates formation of multispecies biofilmsQ31871328
Mucin dynamics in intestinal bacterial infectionQ33393646
Genome-wide transposon mutagenesis reveals a role for pO157 genes in biofilm development in Escherichia coli O157:H7 EDL933Q33547277
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosaQ33582232
Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli.Q34002298
Citrobacter rodentium espB is necessary for signal transduction and for infection of laboratory miceQ34002534
Virulence is positively selected by transmission success between mammalian hostsQ34003664
Pic, an autotransporter protein secreted by different pathogens in the Enterobacteriaceae family, is a potent mucus secretagogueQ34177330
Bacterial Macroscopic Rope-like Fibers with Cytopathic and Adhesive PropertiesQ34186513
Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasiaQ34239798
A bioinformatic strategy for the detection, classification and analysis of bacterial autotransportersQ34384897
Citrobacter rodentium of mice and man.Q34470352
Thin aggregative fimbriae and cellulose enhance long-term survival and persistence of SalmonellaQ34564944
Toll-like receptor 4 contributes to colitis development but not to host defense during Citrobacter rodentium infection in mice.Q34602053
A novel mouse model of Campylobacter jejuni gastroenteritis reveals key pro-inflammatory and tissue protective roles for Toll-like receptor signaling during infectionQ35208160
Attaching-effacing bacteria in animalsQ35998321
Epithelial cells augment barrier function via activation of the Toll-like receptor 2/phosphatidylinositol 3-kinase pathway upon recognition of Salmonella enterica serovar Typhimurium curli fibrils in the gut.Q36558731
Campylobacter jejuni: molecular biology and pathogenesisQ36912126
Roles of motility, chemotaxis, and penetration through and growth in intestinal mucus in the ability of an avirulent strain of Salmonella typhimurium to colonize the large intestine of streptomycin-treated miceQ36998617
Role of RpoS in the virulence of Citrobacter rodentiumQ37033120
The Pic protease of enteroaggregative Escherichia coli promotes intestinal colonization and growth in the presence of mucinQ37204458
Common themes and variations in serine protease autotransportersQ37205333
The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitisQ37264731
Responses to amyloids of microbial and host origin are mediated through toll-like receptor 2.Q37349670
Toll-like receptors 1 and 2 cooperatively mediate immune responses to curli, a common amyloid from enterobacterial biofilmsQ37405926
Novel roles for the AIDA adhesin from diarrheagenic Escherichia coli: cell aggregation and biofilm formationQ37623376
Mucin dynamics and enteric pathogens.Q37853367
Serine protease autotransporters of enterobacteriaceae (SPATEs): biogenesis and functionQ37954294
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectpathogenesisQ372016
CitrobacterQ134081
Citrobacter rodentiumQ16975761
P304page(s)2636-2650
P577publication date2015-04-20
P1433published inInfection and ImmunityQ6029193
P1476titleThe Serine Protease Autotransporter Pic Modulates Citrobacter rodentium Pathogenesis and Its Innate Recognition by the Host
P478volume83

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cites work (P2860)
Q50084713Frontline defenders: Goblet cell mediators dictate host-microbe interactions in the intestinal tract during health and disease
Q36096975Immunological aspects of intestinal mucus and mucins.
Q96816103Mucus layer modeling of human colonoids during infection with enteroaggragative E. coli
Q90520172Pic-Producing Escherichia coli Induces High Production of Proinflammatory Mediators by the Host Leading to Death by Sepsis
Q42323873Recognition of protein-linked glycans as a determinant of peptidase activity
Q36869006The serine protease Pic as a virulence factor of atypical enteropathogenic Escherichia coli

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