An essential role for free radicals and derived species in signal transduction.

scientific article published on February 1997

An essential role for free radicals and derived species in signal transduction. is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1096/FASEBJ.11.2.9039953
P698PubMed publication ID9039953

P2093author name stringLander HM
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)118-124
P577publication date1997-02-01
P1433published inFASEB JournalQ520194
P1476titleAn essential role for free radicals and derived species in signal transduction
P478volume11

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cites work (P2860)
Q267658191,4-Dihydropyridine Derivatives: Dihydronicotinamide Analogues-Model Compounds Targeting Oxidative Stress
Q39885131A heteroplasmic, not homoplasmic, mitochondrial DNA mutation promotes tumorigenesis via alteration in reactive oxygen species generation and apoptosis
Q38712122A holistic view of cancer bioenergetics: mitochondrial function and respiration play fundamental roles in the development and progression of diverse tumors
Q41958893A hypothesis on chemical mechanism of the effect of hydrogen
Q33319573A novel OxyR sensor and regulator of hydrogen peroxide stress with one cysteine residue in Deinococcus radiodurans
Q36792555A systematic review of known mechanisms of hydroxyurea-induced fetal hemoglobin for treatment of sickle cell disease
Q37016484Ageing, oxidative stress and cancer: paradigms in parallax
Q35947149Alcohol, oxidative stress, and free radical damage
Q28486763Alkyl hydroperoxide reductase subunit C (AhpC) protects bacterial and human cells against reactive nitrogen intermediates
Q40815855Alteration of culture regime modifies antioxidant defenses independent of intracellular reactive oxygen levels and resistance to severe oxidative stress within confluent Caco-2 "intestinal cells".
Q42487544Alterations in muscarinic receptor-coupled phosphoinositide hydrolysis and AP-1 activation in Alzheimer's disease cybrid cells
Q34198896Antiallodynic effect of intrathecal epigallocatechin-3-gallate due to suppression of reactive oxygen species
Q44368267Antioxidant activity of different dihydropyridines
Q35037504Antioxidants, oxidative damage and oxygen deprivation stress: a review
Q61296240Atrial natriuretic peptide reduces expression of TNF-α mRNA during reperfusion of the rat liver upon decreased activation of NF-κB and AP-1
Q38306015Attenuation of macrophage apoptosis by the cAMP-signaling system
Q77374578BMD188, A novel hydroxamic acid compound, demonstrates potent anti-prostate cancer effects in vitro and in vivo by inducing apoptosis: requirements for mitochondria, reactive oxygen species, and proteases
Q41107434Beta subunits of the olfactory cyclic nucleotide-gated channel form a nitric oxide activated Ca2+ channel
Q44528489Beta-carotene production and sclerotial differentiation in Sclerotinia minor.
Q27687390Bioeffects of static magnetic fields: oxidative stress, genotoxic effects, and cancer studies
Q48563269Biphasic effect of hydrogen peroxide on field potentials in rat hippocampal slices
Q38789891CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases
Q36498699CYP2E1 and oxidative liver injury by alcohol
Q59101146Caenorhabditis elegans as model system in pharmacology and toxicology: effects of flavonoids on redox-sensitive signalling pathways and ageing
Q34527977Calcium and oxidative stress: from cell signaling to cell death
Q37424064Cancer-derived immunoglobulin G promotes tumor cell growth and proliferation through inducing production of reactive oxygen species
Q36311595Carcinogenic effect of nickel compounds
Q53695762Cardioprotection by Intermittent Hypoxia Conditioning: Evidence, Mechanisms and Therapeutic Potential.
Q35757568Cardioprotective effects of cerium oxide nanoparticles in a transgenic murine model of cardiomyopathy
Q38822861Cell Wall Metabolism in Response to Abiotic Stress
Q42823094Cell proliferation induced by 8-oxoguanosine and 8-methylguanosine, two adducts produced by free radical attack on ribonucleosides and RNA.
Q37203208Cell signaling via the P2X(7) nucleotide receptor: linkage to ROS production, gene transcription, and receptor trafficking
Q39102546Characteristic tandem mass spectral features under various collision chemistries for site-specific identification of protein S-glutathionylation
Q77208323Chromium can reduce the mutagenic effects of benzo[a]pyrene diolepoxide in normal human fibroblasts via an oxidative stress mechanism
Q39926278Competitive nuclear export of cyclin D1 and Hic-5 regulates anchorage dependence of cell growth and survival
Q36846350Cordycepin Prevents Bone Loss through Inhibiting Osteoclastogenesis by Scavenging ROS Generation
Q27627405Crystal structure of S-glutathiolated carbonic anhydrase III
Q27757619Crystal structure of a novel human peroxidase enzyme at 2.0 A resolution
Q35044150Cyclosporin A-induced free radical generation is not mediated by cytochrome P-450.
Q31951654Cytochromes and oxygen radicals as putative members of the oxygen sensing pathway
Q54385628Decisive role of lipopolysaccharide in activating nitric oxide and cytokine production by the probiotic Escherichia coli strain Nissle 1917.
Q33761274Decoding NADPH oxidase 4 expression in human tumors
Q33696701Development of a DNA-binding TEMPO derivative for evaluation of nuclear oxidative stress and its application in living cells
Q34371022Developmental regulation of antioxidant enzymes and their impact on neonatal lung disease
Q52165005Differential developmental expression and cell type specificity of Dictyostelium catalases and their response to oxidative stress and UV-light.
Q23918458Differential role of hydrogen peroxide in UV-induced signal transduction
Q44082370Differential susceptibilities of serine/threonine phosphatases to oxidative and nitrosative stress.
Q111622661Differentiation and hydrogen peroxide production in Sclerotium rolfsii are induced by the oxidizing growth factors, light and iron
Q36775054Dihydroartemisinin attenuates lipopolysaccharide-induced osteoclastogenesis and bone loss via the mitochondria-dependent apoptosis pathway
Q38895879Dihydropyridine calcium channel blockers and renal disease
Q36376476Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and fas ligand expression
Q34819526Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta
Q73503940Dynamic state of S-nitrosothiols in human plasma and whole blood
Q36727834Ebselen Is a Potential Anti-Osteoporosis Agent by Suppressing Receptor Activator of Nuclear Factor Kappa-B Ligand-Induced Osteoclast Differentiation In vitro and Lipopolysaccharide-Induced Inflammatory Bone Destruction In vivo
Q89949107Effect of diabetes blood-stasis syndrome and Xuefu Zhuyu decoction on ROS-ERK1/2 signaling pathway in rat retina Müller cells
Q40896357Effects of beta-carotene on antioxidant enzyme activity, intracellular reactive oxygen and membrane integrity within post confluent Caco-2 intestinal cells
Q77726002Effects of modulators of the production and degradation of hydrogen peroxide on erythropoietin synthesis
Q36230027Electrophysiological and behavioral changes by phosphodiesterase 4 inhibitor in a rat model of alcoholic neuropathy
Q39672036Elevated expression of protein kinase Cδ induces cell scattering upon serum deprivation
Q42869980Endocytosis and cancer
Q33808110Enhancement of allergic inflammation by diesel exhaust particles: permissive role of reactive oxygen species
Q36368100Essential role of P-selectin in the initiation of the inflammatory response induced by hemorrhage and reinfusion
Q36400478Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock
Q89621908Evaluation of Antioxidative Activity of Agrimonia pilosa-Ledeb Leaves on Non-lipid Oxidative Damage
Q57300228Evaluation of the Effectiveness of Protective Patches on Acupoints to Preserve the Bioenergetic Status against Magnetic Fields
Q33811991Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene
Q34016655Exercise-induced oxidative stress: cellular mechanisms and impact on muscle force production
Q37829472Experimental and clinical evidence for modification of hepatic ischaemia-reperfusion injury by N-acetylcysteine during major liver surgery
Q73663735Extracellular H(2)O(2) induced by oligogalacturonides is not involved in the inhibition of the auxin-regulated rolB gene expression in tobacco leaf explants
Q28510183Fer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell adhesion
Q28205310Free radicals, antioxidants, and nutrition
Q44230278Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase
Q51245699Gene expression profile following an oral unsaturated fat load in abdominal obese subjects.
Q36955094Genes responsive to both oxidant stress and loss of estrogen receptor function identify a poor prognosis group of estrogen receptor positive primary breast cancers
Q34816445Glutathione catabolism as a signaling mechanism
Q52170135Growth factor receptor gene and protein expressions in the human lens.
Q35597438Gut mucosal granulocyte activation precedes nitric oxide production: studies in coeliac patients challenged with gluten and corn
Q28571929H(2)O(2)-induced egr-1, fra-1, and c-jun gene expression is mediated by tyrosine kinase in aortic smooth muscle cells
Q42881869Heparin inhibits Ca2+/calmodulin-dependent kinase II activation and c-fos induction in mesangial cells.
Q44430583High glucose accelerates MCP-1 production via p38 MAPK in vascular endothelial cells
Q41704156High-magnitude compression accelerates the premature senescence of nucleus pulposus cells via the p38 MAPK-ROS pathway
Q29304037Human mitochondrial branched chain aminotransferase: structural basis for substrate specificity and role of redox active cysteines
Q44213499Human platelet inhibition of Toxoplasma gondii growth.
Q40983538Hydroxyl radical scavengers inhibit TNF-alpha production in mononuclear cells but not in polymorphonuclear leukocytes
Q36185978Hyperbilirubinemia exaggerates endotoxin-induced hypothermia.
Q36953307Hypoxia-generated superoxide induces the development of the adhesion phenotype.
Q42120935Identification of cardiac oxidoreductase(s) involved in the metabolism of the lipid peroxidation-derived aldehyde-4-hydroxynonenal
Q54256751Identification of diverse defense mechanisms in rainbow trout red blood cells in response to halted replication of VHS virus.
Q39879692Immune effector cells produce lethal DNA damage in cells treated with a thiopurine
Q34249956Impaired homocysteine metabolism and atherothrombotic disease
Q39549429Impairment of long-term potentiation and associative memory in mice that overexpress extracellular superoxide dismutase.
Q46641278Impairments in hippocampal synaptic plasticity following prenatal ethanol exposure are dependent on glutathione levels
Q37521873Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis
Q47271539In Vitro-In Vivo Dose Response of Ursolic Acid, Sulforaphane, PEITC, and Curcumin in Cancer Prevention.
Q40879108Increase of mitochondria and mitochondrial DNA in response to oxidative stress in human cells
Q52537902Increased H2O2, vascular endothelial growth factor and receptors in the retina of the BBZ/Wor diabetic rat.
Q35586674Increased Nox2 expression in human cardiomyocytes after acute myocardial infarction
Q36487722Increased expression of pAKT is associated with radiation resistance in cervical cancer
Q39915079Induction of copper/zinc-superoxide dismutase by CCL5/CCR5 activation causes tumour necrosis factor-alpha and reactive oxygen species production in macrophages
Q43832787Induction of endothelin-1 expression by oxidative stress in vascular smooth muscle cells
Q77984002Induction of type 1 programmed cell death in U937 cells by the antioxidant, butylated hydroxy-toluene or the free radical spin trap, NTBN
Q34772299Interaction between reactive oxygen metabolites and nitric oxide in oxidant tolerance.
Q43724612Interleukin 1-induced cyclooxygenase and nitric oxide synthase gene expression in the rat dorsal root ganglia is modulated by antioxidants
Q40655454Involvement of CD4 D3-D4 membrane proximal extracellular domain for the inhibitory effect of oxidative stress on activation-induced CD4 down-regulation and its possible role for T cell activation.
Q44360909Involvement of Ras in survival responsiveness to nitric oxide toxicity in pheochromocytoma cells
Q44506014Involvement of hydrogen peroxide in mistletoe lectin-II-induced apoptosis of myeloleukemic U937 cells
Q53998468Involvement of p38 mitogen-activated protein kinase and apoptosis signal-regulating kinase-1 in nitric oxide-induced cell death in PC12 cells.
Q34717533Lessons from chronic intermittent and sustained hypoxia at high altitudes
Q34348769Lipid peroxidation in aging and age-dependent diseases
Q89909631Lipid peroxidation: Its effects on the formulation and use of pharmaceutical emulsions
Q92929174Literature-Based Enrichment Insights into Redox Control of Vascular Biology
Q64062953Low‑frequency pulsed electromagnetic field inhibits RANKL‑induced osteoclastic differentiation in RAW264.7 cells by scavenging reactive oxygen species
Q35238645Lung ischemia-reperfusion injury: implications of oxidative stress and platelet-arteriolar wall interactions
Q42207865Mangosteen xanthones suppress hepatitis C virus genome replication
Q37088995Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras.
Q36466156Metabolism of the lipid peroxidation product, 4-hydroxy-trans-2-nonenal, in isolated perfused rat heart
Q29616610Mitochondria and cancer
Q28397259Mitochondria and reactive oxygen species: physiology and pathophysiology
Q34264422Mitochondrial contributions to cancer cell physiology: potential for drug development
Q47738377Mitochondrial pathway is involved in hydrogen-peroxide-induced apoptotic cell death of oligodendrocytes
Q35542465Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K(+) channel in cardiac function and cardioprotection.
Q30374674Mitochondrial reactive oxygen species production in excitable cells: modulators of mitochondrial and cell function.
Q31107274Mitogenic potential inducible by He:Ne laser in human lymphocytes in vitro
Q33666814Modulation of protein kinases and protein phosphatases by reactive oxygen species: implications for hippocampal synaptic plasticity
Q41729394Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging
Q23911183Molecular mechanisms of arsenic carcinogenesis
Q39734542Mulberry fruit protects dopaminergic neurons in toxin-induced Parkinson's disease models
Q24568289N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities
Q73303463NADPH oxidase activity is required for endothelial cell proliferation and migration
Q37448881NADPH oxidase gp91(phox) contributes to RANKL-induced osteoclast differentiation by upregulating NFATc1
Q26827634NADPH oxidase- and mitochondria-derived reactive oxygen species in proinflammatory microglial activation: a bipartisan affair?
Q24643679NF-kappaB and AP-1 activation by nitric oxide attenuated apoptotic cell death in RAW 264.7 macrophages
Q64972013NOS3 Inhibition Confers Post-Ischemic Protection to Young and Aging White Matter Integrity by Conserving Mitochondrial Dynamics and Miro-2 Levels.
Q41684459Nardosinone Suppresses RANKL-Induced Osteoclastogenesis and Attenuates Lipopolysaccharide-Induced Alveolar Bone Resorption
Q34342650Natural killer cells and nitric oxide.
Q33701967Neutrophils and renal failure
Q44040667Nitration/S-nitrosation of proteins by peroxynitrite-treatment and subsequent modification by glutathione S-transferase and glutathione peroxidase
Q44537860Nitric oxide and cGMP activate the Ras-MAP kinase pathway-stimulating protein tyrosine phosphorylation in rabbit aortic endothelial cells
Q41127967Nitric oxide and cancer
Q77164340Nitric oxide and its role in apoptosis
Q33912904Nitric oxide and redox regulation in the liver: Part I. General considerations and redox biology in hepatitis
Q34565478Nitric oxide and the other cyclic nucleotide
Q34134480Nitric oxide and the regulation of gene expression
Q27485884Nitric oxide and virus infection
Q41821993Non-immortalized human tenocyte cultures as a vehicle for understanding cellular aspects to tendinopathy
Q37212642Novel Role of Endogenous Catalase in Macrophage Polarization in Adipose Tissue
Q77725761Novel mechanism by which hemoglobin induces constriction of cerebral arteries
Q28513396Nucleotide receptor signaling in murine macrophages is linked to reactive oxygen species generation
Q36174261Nucleotide receptor signalling and the generation of reactive oxygen species
Q55265714Olive oil polyphenols reduce oxysterols -induced redox imbalance and pro-inflammatory response in intestinal cells.
Q46574423Opposite effects of alpha-lipoic acid on antioxidation and long-term potentiation in control and chronically lead-exposed rats
Q44627930Overexpression of Prdx6 reduces H2O2 but does not prevent diet-induced atherosclerosis in the aortic root
Q59792428Overuse injuries in sport: a comprehensive overview
Q57471863Oxidant stress induction and signalling in xenografted (human breast cancer-tissues) plus estradiol treated or N-ethyl-N-nitrosourea treated female rats via altered estrogen sulfotransferase (rSULT1E1) expressions and SOD1/catalase regulations
Q36840786Oxidative Stress in the Developing Rat Brain due to Production of Reactive Oxygen and Nitrogen Species
Q41685016Oxidative damage in chemical teratogenesis
Q33853144Oxidative stress and gene regulation
Q38127242Oxidative stress and hepatitis C virus
Q35008614Oxidative stress and redox modulation potential in type 1 diabetes.
Q34342998Oxidative stress and vascular smooth muscle cell function in liver disease
Q43615224Oxidative stress causes nuclear factor-kappaB activation in acute hypovolemic hemorrhagic shock
Q73251011Oxidative stress differentially modulates phosphorylation of ERK, p38 and CREB induced by NGF or EGF in PC12 cells
Q36953696Oxidative stress impairs endothelial progenitor cell function
Q40672194Oxidative stress regulated genes in nigral dopaminergic neuronal cells: correlation with the known pathology in Parkinson's disease
Q34387346Oxidative stress-related molecules and liver fibrosis
Q34103121Oxidative-dependent integration of signal transduction with intercellular gap junctional communication in the control of gene expression
Q40706208PA-X-associated early alleviation of the acute lung injury contributes to the attenuation of a highly pathogenic H5N1 avian influenza virus in mice
Q55387147PI3K/Akt/mTOR Signaling Pathway and the Biphasic Effect of Arsenic in Carcinogenesis.
Q63232698Pathological Relevance of the Natural Immune System
Q92501704Peroxiredoxin II negatively regulates BMP2-induced osteoblast differentiation and bone formation via PP2A Cα-mediated Smad1/5/9 dephosphorylation
Q34729815Peroxiredoxin II negatively regulates lipopolysaccharide-induced osteoclast formation and bone loss via JNK and STAT3
Q44283543Peroxynitrite generated in the rat spinal cord induces apoptotic cell death and activates caspase-3.
Q41838717Peroxynitrite modulates tyrosine phosphorylation and phosphoinositide signalling in human neuroblastoma SH-SY5Y cells: attenuated effects in human 1321N1 astrocytoma cells
Q43615239Peroxynitrite-dependent activation of src tyrosine kinases lyn and hck in erythrocytes is under mechanistically different pathways of redox control
Q45274479Phenotype of mice and macrophages deficient in both phagocyte oxidase and inducible nitric oxide synthase.
Q28580726Pivotal role of attractin in cell survival under oxidative stress in the zitter rat brain with genetic spongiform encephalopathy
Q36487347Plasma redox status is impaired in the portacaval shunted rat--the risk of the reduced antioxidant ability.
Q36168568Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells
Q77715240Probing cellular protein targets of H2O2 with fluorescein-conjugated iodoacetamide and antibodies to fluorescein
Q34392509Protection by glia-conditioned medium in a cell model of Huntington disease
Q37403451Protective effects of Centella asiatica leaf extract on dimethylnitrosamine‑induced liver injury in rats
Q42526837Protective properties of artichoke (Cynara scolymus) against oxidative stress induced in cultured endothelial cells and monocytes
Q34626008Pulse-chase analysis of procollagen biosynthesis by azidohomoalanine labeling.
Q33668416RNA Viruses: ROS-Mediated Cell Death
Q42056199Rac1, and not Rac2, is involved in the regulation of the intracellular hydrogen peroxide level in HepG2 cells
Q77654090Radiation-sensitive tyrosine phosphorylation of cellular proteins: sensitive to changes in GSH content induced by pretreatment with N-acetyl-L-cysteine or L-buthionine-S,R-sulfoximine
Q38539540Radical Oxygen Species, Exercise and Aging: An Update
Q36404225Rapid interferon gamma-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-deficient mice
Q33840513Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity
Q77799748Reactive oxygen intermediates as mediators of programmed cell death in plants and animals
Q77900065Reactive oxygen species are required for the phagocytosis of myelin by macrophages
Q33516173Reconciling conflicting clinical studies of antioxidant supplementation as HIV therapy: a mathematical approach
Q37802379Redox Balance in the Pathogenesis of Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities
Q44069263Redox control of tissue factor expression in smooth muscle cells and other vascular cells
Q73000461Redox modulation of cell surface protein thiols in U937 lymphoma cells: the role of gamma-glutamyl transpeptidase-dependent H2O2 production and S-thiolation
Q34623471Redox paradox: insulin action is facilitated by insulin-stimulated reactive oxygen species with multiple potential signaling targets
Q31127419Redox regulation of OxyR requires specific disulfide bond formation involving a rapid kinetic reaction path
Q34773896Redox signaling
Q33957112Redox-dependent signal transduction
Q43577685Regulation of vascular smooth muscle cell growth by aldose reductase
Q28679172Repression of gene expression by oxidative stress
Q36648390Reversing drug resistance in bcl-2-expressing tumor cells by depleting glutathione
Q28396898Review of experimental animal models of acute pancreatitis
Q33965815Role for mitochondrial oxidants as regulators of cellular metabolism
Q26740342Role of ROS and RNS Sources in Physiological and Pathological Conditions
Q34191797Role of free radicals in viral pathogenesis and mutation
Q33712193Role of oxidative stress in the pathogenesis of caerulein-induced acute pancreatitis.
Q34749376Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease
Q23924205Role of reactive oxygen species and MAPKs in vanadate-induced G2/M phase arrest
Q41867511Role of reactive oxygen species in the signalling cascade of cyclosporine A-mediated up-regulation of eNOS in vascular endothelial cells
Q37011471Role of the p50 subunit of NF-kappaB in vitamin E-induced changes in mice treated with the peroxisome proliferator, ciprofibrate
Q40176229Salsolinol, an endogenous neurotoxin, activates JNK and NF-kappaB signaling pathways in human neuroblastoma cells
Q36956865Severe mitochondrial damage associated with low-dose radiation sensitivity in ATM- and NBS1-deficient cells.
Q42086318Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways
Q42315017Signalling mechanisms mediating Zn2+-induced TRPM2 channel activation and cell death in microglial cells
Q34139832Significance of ROS in oxygen sensing in cell systems with sensitivity to physiological hypoxia
Q77908042Stability of S-nitrosothiols in presence of copper, zinc-superoxide dismutase
Q28379504Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production
Q41954007Stimulation of multiple mitogen-activated protein kinase sub-families by oxidative stress and phosphorylation of the small heat shock protein, HSP25/27, in neonatal ventricular myocytes
Q27631186Structural basis of the redox switch in the OxyR transcription factor
Q43146238Superoxide inhibits guanine nucleotide exchange factor (GEF) action on Ras, but not on Rho, through desensitization of Ras to GEF.
Q48416077Targeted tissue oxidation in the cerebral cortex induces local prolonged depolarization and cortical spreading depression in the rat brain.
Q42330276Tempol Ameliorates and Prevents Mechanical Hyperalgesia in a Rat Model of Chemotherapy-Induced Neuropathic Pain
Q22337136Teratogenic mechanisms of medical drugs
Q53703719The Effects of Aronia melanocarpa 'Viking' Extracts in Attenuating RANKL-Induced Osteoclastic Differentiation by Inhibiting ROS Generation and c-FOS/NFATc1 Signaling.
Q34696040The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes
Q37729333The Glyoxalase System and Methylglyoxal-Derived Carbonyl Stress in Sepsis: Glycotoxic Aspects of Sepsis Pathophysiology
Q35577670The Two Faces of Oxygen
Q35502836The effect of phosphodiesterase-4-specific inhibitor in the rat model of spinal nerve ligation
Q41311155The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
Q42971599The multiplex function of nitric oxide in (auto)immunity
Q30357117The oxidative burst reaction in mammalian cells depends on gravity.
Q35038220The oxygen sensing signal cascade under the influence of reactive oxygen species
Q34998147The role of NF-kappaB in the regulation of cell stress responses
Q38214602The role of intracellular zinc release in aging, oxidative stress, and Alzheimer's disease
Q38394090The sodium/multivitamin transporter: a multipotent system with therapeutic implications.
Q34325036Transcription factors p53 and HIF-1alpha as targets of nitric oxide
Q23911187UV induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal C1 41 cells through hydrogen peroxide
Q23911185Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis
Q23911186Vanadium-induced nuclear factor of activated T cells activation through hydrogen peroxide
Q58200826Viability, susceptibility to peroxidation and fatty acid composition of boar semen during liquid storage
Q93187583Vitamin B5 inhibit RANKL induced osteoclastogenesis and ovariectomy induced osteoporosis by scavenging ROS generation
Q34029908Withaferin A-caused production of intracellular reactive oxygen species modulates apoptosis via PI3K/Akt and JNKinase in rabbit articular chondrocytes
Q46605120Xanthotoxin prevents bone loss in ovariectomized mice through the inhibition of RANKL-induced osteoclastogenesis
Q74043506[Current topics in vascular biology: an update for the 21st century]
Q43701554cAMP potentiates H(2)O(2)-induced ERK1/2 phosphorylation without the requirement for MEK1/2 phosphorylation
Q35788948mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination
Q43733615tert-Butyl hydroperoxide-induced lipid signaling in hepatocytes: involvement of glutathione and free radicals.

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