bromocriptine

medication which has significant effects on dopamine levels in the brain

Wikidata entity: Q413581

C₃₂H₄₀BrN₅O₅ (P274)


Wikimedia Commons category is Bromocriptine



Quantities

P4250defined daily dose40
P2067mass653.221

P3780 active ingredient in ... Q47521428 (Cycloset) Cycloset
P3780 active ingredient in ... Q47521965 (Parlodel) Parlodel
P233 canonical SMILES String CC(C)CC1C(=O)N2CCCC2C3(N1C(=O)C(O3)(C(C)C)NC(=O)C4CN(C5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O ???
P373 Commons category String Bromocriptine ???
P527 has part(s) ... Q623 (carbon) carbon
P527 has part(s) ... Q627 (nitrogen) nitrogen
P527 has part(s) ... Q879 (bromine) bromine
P366 has use ... Q12140 (medication) medication
P8224 image of molecular model or crystal lattice model CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/Bromocriptine%20ball-and-stick.png ???
P31 instance of ... Q113145171 (type of chemical entity) type of chemical entity
P2017 isomeric SMILES String CC(C)C[C@H]1C(=O)N2CCC[C@H]2[C@]3(N1C(=O)[C@](O3)(C(C)C)NC(=O)[C@H]4CN([C@@H]5CC6=C(NC7=CC=CC(=C67)C5=C4)Br)C)O ???
P8026 LiverTox likelihood score ... Q83284515 (LiverTox toxicity likelihood category D) LiverTox toxicity likelihood category D
P2175 medical condition treated ... Q11085 (Parkinson's disease) Parkinson's disease
P2175 medical condition treated ... Q334655 (amenorrhea) amenorrhea
P2175 medical condition treated ... Q179399 (infertility) infertility
P2175 medical condition treated ... Q189580 (acromegaly) acromegaly
P2175 medical condition treated ... Q938107 (hypogonadism) hypogonadism
P2175 medical condition treated ... Q954831 (prolactinoma) prolactinoma
P2175 medical condition treated ... Q18556776 (prolactin producing pituitary tumor) prolactin producing pituitary tumor
P2175 medical condition treated ... Q1424956 (neuroleptic malignant syndrome) neuroleptic malignant syndrome
P2175 medical condition treated ... Q1433936 (hyperprolactinemia) hyperprolactinemia
P129 physically interacts with ... Q288797 (5-hydroxytryptamine receptor 1B) 5-hydroxytryptamine receptor 1B
P129 physically interacts with ... Q308856 (Dopamine receptor D4) Dopamine receptor D4
P129 physically interacts with ... Q4639596 (5-hydroxytryptamine receptor 2B) 5-hydroxytryptamine receptor 2B
P129 physically interacts with ... Q4734891 (Adrenoceptor alpha 2C) Adrenoceptor alpha 2C
P129 physically interacts with ... Q4734892 (Adrenoceptor alpha 2A) Adrenoceptor alpha 2A
P129 physically interacts with ... Q21108118 (5-hydroxytryptamine receptor 2C) 5-hydroxytryptamine receptor 2C
P129 physically interacts with ... Q21109363 (5-hydroxytryptamine receptor 6) 5-hydroxytryptamine receptor 6
P129 physically interacts with ... Q21110867 (Dopamine receptor D1) Dopamine receptor D1
P129 physically interacts with ... Q1949517 (5-hydroxytryptamine receptor 2A) 5-hydroxytryptamine receptor 2A
P129 physically interacts with ... Q2034004 (Dopamine receptor D2) Dopamine receptor D2
P129 physically interacts with ... Q21110872 (Dopamine receptor D3) Dopamine receptor D3
P129 physically interacts with ... Q21115043 (5-hydroxytryptamine receptor 1A) 5-hydroxytryptamine receptor 1A
P129 physically interacts with ... Q21115046 (5-hydroxytryptamine receptor 1D) 5-hydroxytryptamine receptor 1D
P129 physically interacts with ... Q21131500 (Dopamine receptor D5) Dopamine receptor D5
P129 physically interacts with ... Q21141045 (Adrenoceptor alpha 2B) Adrenoceptor alpha 2B
P3489 pregnancy category ... Q3679189 (Australian pregnancy category A) Australian pregnancy category A
P3489 pregnancy category ... Q28123616 (US pregnancy category B) US pregnancy category B
P5555 schematic CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/Bromocriptine%20synthesis.png ???
P769 significant drug interaction ... Q251347 (haloperidol) haloperidol
P769 significant drug interaction ... Q277785 (perindopril) perindopril
P769 significant drug interaction ... Q58376 (fluphenazine) fluphenazine
P769 significant drug interaction ... Q144085 (pimozide) pimozide
P769 significant drug interaction ... Q174259 (droperidol) droperidol
P769 significant drug interaction ... Q388801 (furosemide) furosemide
P769 significant drug interaction ... Q407972 (chlorpromazine) chlorpromazine
P769 significant drug interaction ... Q410291 (verapamil) verapamil
P769 significant drug interaction ... Q412443 (risperidone) risperidone
P769 significant drug interaction ... Q412666 (ramipril) ramipril
P769 significant drug interaction ... Q421119 (captopril) captopril
P769 significant drug interaction ... Q422185 (enalapril) enalapril
P769 significant drug interaction ... Q422229 (diltiazem) diltiazem
P769 significant drug interaction ... Q422418 ((RS)-sulpiride) (RS)-sulpiride
P769 significant drug interaction ... Q423930 (hydrochlorothiazide) hydrochlorothiazide
P769 significant drug interaction ... Q425289 (chlorthalidone) chlorthalidone
P769 significant drug interaction ... Q1078392 (indapamide) indapamide
P769 significant drug interaction ... Q425293 (fosinopril) fosinopril
P769 significant drug interaction ... Q596022 (quinapril) quinapril
P769 significant drug interaction ... Q929420 (trandolapril) trandolapril
P769 significant drug interaction ... Q47495698 (lisinopril dihydrate) lisinopril dihydrate
P3364 stereoisomer of ... Q27166519 (LSM-5805) LSM-5805
P3364 stereoisomer of ... Q82393823 ((5'alpha,8alpha)-2-Bromo-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman) (5'alpha,8alpha)-2-Bromo-12'-hydroxy-5'-(2-methylpropyl)-3',6',18-trioxo-2'-(propan-2-yl)ergotaman
P279 subclass of ... Q193430 (heterocyclic compound) heterocyclic compound
P279 subclass of ... Q49873234 (ergoline alkaloid) ergoline alkaloid
P279 subclass of ... Q109476791 (biogenic 2,5-diketopiperazine) biogenic 2,5-diketopiperazine
P2868 subject has role ... Q600203 (dopamine agonist) dopamine agonist
P2868 subject has role ... Q3579672 (antiparkinson) antiparkinson
P2868 subject has role ... Q16875676 (hormone antagonist) hormone antagonist
P2275 World Health Organisation international non-proprietary name Monolingualtext bromocriptine ???

External Ids
P267ATC codeG02CB01
P267ATC codeN04BC01
P231CAS Registry Number25614-03-3
P683ChEBI ID3181
P592ChEMBL IDCHEMBL493
P661ChemSpider ID28858
P715DrugBank IDDB01200
P11198DrugCentral ID403
P8494DSSTOX compound identifierDTXCID602687
P3117DSSTox substance IDDTXSID1022687
P232EC number247-128-5
P2566ECHA Substance Infocard ID100.042.829
P9635electronic Essential Medicines List medicine ID592
P4746Elhuyar ZTH ID021884
P1417Encyclopædia Britannica Online IDscience/bromocriptine
P3219Encyclopædia Universalis IDbromocriptine
P646Freebase ID/m/02xpx1
P12385Gran Enciclopèdia Catalana IDbromocriptina
P1296Gran Enciclopèdia Catalana ID (former scheme)0223410
P595Guide to Pharmacology Ligand ID35
P2057Human Metabolome Database IDHMDB0015331
P234InChIInChI=1S/C32H40BrN5O5/c1-16(2)12-24-29(40)37-11-7-10-25(37)32(42)38(24)30(41)31(43-32,17(3)4)35-28(39)18-13-20-19-8-6-9-22-26(19)21(27(33)34-22)14-23(20)36(5)15-18/h6,8-9,13,16-18,23-25,34,42H,7,10-12,14-15H2,1-5H3,(H,35,39)/t18-,23-,24+,25+,31-,32+/m1/s1
P235InChIKeyOZVBMTJYIDMWIL-AYFBDAFISA-N
P665KEGG IDC06856
P665KEGG IDD03165
P7830LiverTox IDBromocriptine
P6689MassBank accession IDMSBNK-Waters-WA001779
P6689MassBank accession IDMSBNK-Waters-WA001780
P6689MassBank accession IDMSBNK-Waters-WA001781
P6689MassBank accession IDMSBNK-Waters-WA001782
P6689MassBank accession IDMSBNK-Waters-WA001783
P6689MassBank accession IDMSBNK-Waters-WA001784
P6689MassBank accession IDMSBNK-Waters-WA001785
P10245MedlinePlus drug identifiera682079
P6694MeSH concept IDM0002948
P486MeSH descriptor IDD001971
P672MeSH tree codeD03.132.327.412.100
P672MeSH tree codeD03.633.400.439.131
P672MeSH tree codeD03.633.400.562.100
P6366Microsoft Academic ID (discontinued)2776856834
P2004NALT ID19966
P2115NDF-RT IDN0000147732
P10283OpenAlex IDC2776856834
P3636PDB ligand ID08Y
P638PDB structure ID3UA1
P11199Probes And Drugs IDPD009743
P662PubChem CID31101
P1579Reaxys registry number741357
P3345RxNorm CUI1760
P5076Römpp online IDRD-02-02707
P5082Store medisinske leksikon IDbromokriptin
P2877SureChEMBL ID25297
P2892UMLS CUIC0006230
P2892UMLS CUIC0701351
P11089UniChem compound ID16129
P652UNII3A64E3G5ZO
P11143WikiProjectMed IDBromocriptine
P3350World Health Organisation international non-proprietary name numeric ID3365

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