Adrenoceptor alpha 2A

mammalian protein found in Homo sapiens

Wikidata entity: Q4734892



P682 biological process ... Q828130 (signal transduction) signal transduction
P682 biological process ... Q14599352 (Ras protein signal transduction) Ras protein signal transduction
P682 biological process ... Q14633891 (positive regulation of cell population proliferation) positive regulation of cell population proliferation
P682 biological process ... Q14758909 (G protein-coupled receptor signaling pathway) G protein-coupled receptor signaling pathway
P682 biological process ... Q14758919 (positive regulation of cell migration) positive regulation of cell migration
P682 biological process ... Q14758923 (activation of protein kinase B activity) activation of protein kinase B activity
P682 biological process ... Q14758934 (glucose homeostasis) glucose homeostasis
P682 biological process ... Q14758936 (positive regulation of MAPK cascade) positive regulation of MAPK cascade
P682 biological process ... Q14761964 (regulation of insulin secretion) regulation of insulin secretion
P682 biological process ... Q14761966 (negative regulation of lipid catabolic process) negative regulation of lipid catabolic process
P682 biological process ... Q14914598 (receptor transactivation) receptor transactivation
P682 biological process ... Q14916364 (adrenergic receptor signaling pathway) adrenergic receptor signaling pathway
P682 biological process ... Q14916382 (regulation of smooth muscle contraction) regulation of smooth muscle contraction
P682 biological process ... Q21113731 (adenylate cyclase-inhibiting adrenergic receptor signaling pathway) adenylate cyclase-inhibiting adrenergic receptor signaling pathway
P682 biological process ... Q21173419 (phospholipase C-activating adrenergic receptor signaling pathway) phospholipase C-activating adrenergic receptor signaling pathway
P682 biological process ... Q14819467 (platelet activation) platelet activation
P682 biological process ... Q14819860 (negative regulation of norepinephrine secretion) negative regulation of norepinephrine secretion
P682 biological process ... Q14819873 (negative regulation of epinephrine secretion) negative regulation of epinephrine secretion
P682 biological process ... Q14821396 (adenylate cyclase-modulating G protein-coupled receptor signaling pathway) adenylate cyclase-modulating G protein-coupled receptor signaling pathway
P682 biological process ... Q14851900 (positive regulation of cytokine production) positive regulation of cytokine production
P682 biological process ... Q14859618 (regulation of vasoconstriction) regulation of vasoconstriction
P682 biological process ... Q14860468 (adenylate cyclase-activating G protein-coupled receptor signaling pathway) adenylate cyclase-activating G protein-coupled receptor signaling pathway
P682 biological process ... Q14860470 (Rho protein signal transduction) Rho protein signal transduction
P682 biological process ... Q14860509 (activation of protein kinase activity) activation of protein kinase activity
P682 biological process ... Q14864081 (adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway) adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
P682 biological process ... Q14864117 (negative regulation of insulin secretion) negative regulation of insulin secretion
P682 biological process ... Q14864138 (negative regulation of insulin secretion involved in cellular response to glucose stimulus) negative regulation of insulin secretion involved in cellular response to glucose stimulus
P682 biological process ... Q14864671 (negative regulation of calcium ion-dependent exocytosis) negative regulation of calcium ion-dependent exocytosis
P682 biological process ... Q14864686 (positive regulation of MAP kinase activity) positive regulation of MAP kinase activity
P682 biological process ... Q14864687 (positive regulation of epidermal growth factor-activated receptor activity) positive regulation of epidermal growth factor-activated receptor activity
P682 biological process ... Q14864711 (cellular response to hormone stimulus) cellular response to hormone stimulus
P682 biological process ... Q14873902 (negative regulation of calcium ion transport) negative regulation of calcium ion transport
P682 biological process ... Q14873908 (negative regulation of calcium ion transmembrane transporter activity) negative regulation of calcium ion transmembrane transporter activity
P682 biological process ... Q14873990 (actin cytoskeleton organization) actin cytoskeleton organization
P682 biological process ... Q14884137 (positive regulation of wound healing) positive regulation of wound healing
P682 biological process ... Q14888560 (positive regulation of potassium ion transport) positive regulation of potassium ion transport
P682 biological process ... Q14890451 (positive regulation of membrane protein ectodomain proteolysis) positive regulation of membrane protein ectodomain proteolysis
P682 biological process ... Q14904931 (intestinal absorption) intestinal absorption
P682 biological process ... Q14905159 (adenylate cyclase-activating adrenergic receptor signaling pathway) adenylate cyclase-activating adrenergic receptor signaling pathway
P681 cell component ... Q79899 (cytoplasm) cytoplasm
P681 cell component ... Q29548 (plasma membrane) plasma membrane
P681 cell component ... Q14327652 (integral component of membrane) integral component of membrane
P681 cell component ... Q14349455 (membrane) membrane
P681 cell component ... Q14859540 (integral component of plasma membrane) integral component of plasma membrane
P681 cell component ... Q14864700 (basolateral plasma membrane) basolateral plasma membrane
P681 cell component ... Q14877465 (receptor complex) receptor complex
P702 encoded by ... Q17710525 (ADRA2A) ADRA2A
P703 found in taxon ... Q15978631 (Homo sapiens) Homo sapiens
P692 Gene Atlas image CommonsMedia http://commons.wikimedia.org/wiki/Special:FilePath/PBB%20GE%20ADRA2A%20209869%20at%20fs.png ???
P527 has part(s) ... Q24781798 (GPCR, rhodopsin-like, 7TM) GPCR, rhodopsin-like, 7TM
P31 instance of ... Q8054 (protein) protein
P680 molecular function ... Q167149 (protein binding) protein binding
P680 molecular function ... Q14762996 (protein homodimerization activity) protein homodimerization activity
P680 molecular function ... Q14916351 (epinephrine binding) epinephrine binding
P680 molecular function ... Q14916352 (norepinephrine binding) norepinephrine binding
P680 molecular function ... Q14916361 (adrenergic receptor activity) adrenergic receptor activity
P680 molecular function ... Q21113728 (alpha2-adrenergic receptor activity) alpha2-adrenergic receptor activity
P680 molecular function ... Q21116179 (alpha-2C adrenergic receptor binding) alpha-2C adrenergic receptor binding
P680 molecular function ... Q21173417 (alpha-1B adrenergic receptor binding) alpha-1B adrenergic receptor binding
P680 molecular function ... Q14762999 (protein heterodimerization activity) protein heterodimerization activity
P680 molecular function ... Q14817984 (protein kinase binding) protein kinase binding
P680 molecular function ... Q14820643 (signal transducer activity) signal transducer activity
P680 molecular function ... Q14859545 (G protein-coupled receptor activity) G protein-coupled receptor activity
P680 molecular function ... Q14865042 (thioesterase binding) thioesterase binding
P680 molecular function ... Q14888543 (heterotrimeric G-protein binding) heterotrimeric G-protein binding
P361 part of ... Q24786565 (Alpha 2A adrenoceptor) Alpha 2A adrenoceptor
P361 part of ... Q83162561 (GPCR, rhodopsin-like, 7TM, protein family) GPCR, rhodopsin-like, 7TM, protein family
P129 physically interacts with ... Q132621 (epinephrine) epinephrine
P129 physically interacts with ... Q219626 ((−)-ephedrine) (−)-ephedrine
P129 physically interacts with ... Q269111 (apomorphine) apomorphine
P129 physically interacts with ... Q407972 (chlorpromazine) chlorpromazine
P129 physically interacts with ... Q412133 (dexmedetomidine) dexmedetomidine
P129 physically interacts with ... Q412221 (clonidine) clonidine
P129 physically interacts with ... Q186242 (norepinephrine) norepinephrine
P129 physically interacts with ... Q412226 (yohimbine) yohimbine
P129 physically interacts with ... Q413581 (bromocriptine) bromocriptine
P129 physically interacts with ... Q424446 (lisuride) lisuride
P129 physically interacts with ... Q425296 (prazosin) prazosin
P129 physically interacts with ... Q426081 (xylazine) xylazine
P129 physically interacts with ... Q577377 (brimonidine) brimonidine
P129 physically interacts with ... Q4781812 (apraclonidine) apraclonidine
P129 physically interacts with ... Q413772 (tolazoline) tolazoline
P129 physically interacts with ... Q413976 (piribedil) piribedil
P129 physically interacts with ... Q415752 (pergolide) pergolide
P129 physically interacts with ... Q416992 (lurasidone) lurasidone
P129 physically interacts with ... Q417813 (oxymetazoline) oxymetazoline
P129 physically interacts with ... Q420360 (phentolamine) phentolamine
P129 physically interacts with ... Q421930 (mirtazapine) mirtazapine
P129 physically interacts with ... Q423308 (cabergoline) cabergoline
P129 physically interacts with ... Q4836377 (brl-44408) brl-44408
P129 physically interacts with ... Q5613542 (guanabenz) guanabenz
P129 physically interacts with ... Q5613599 (guanfacine) guanfacine
P129 physically interacts with ... Q6592066 (spiroxatrine) spiroxatrine
P129 physically interacts with ... Q7296272 (α-yohimbine) α-yohimbine
P129 physically interacts with ... Q7702355 (terguride) terguride
P129 physically interacts with ... Q12745763 (levonordefrin) levonordefrin
P129 physically interacts with ... Q21098843 (WB-4101) WB-4101
P129 physically interacts with ... Q27105817 (apraclonidine hydrochloride) apraclonidine hydrochloride
P129 physically interacts with ... Q27106427 (dipivefrin hydrochloride) dipivefrin hydrochloride
P129 physically interacts with ... Q27107602 (oxymetazoline hydrochloride) oxymetazoline hydrochloride
P129 physically interacts with ... Q27107723 (phenoxybenzamine hydrochloride) phenoxybenzamine hydrochloride
P129 physically interacts with ... Q27114321 (dexmedetomidine hydrochloride) dexmedetomidine hydrochloride

External Ids
P705Ensembl protein IDENSP00000280155
P638PDB structure ID1HLL
P638PDB structure ID1HO9
P638PDB structure ID1HOD
P638PDB structure ID1HOF
P637RefSeq protein IDNP_000672
P352UniProt protein IDP08913

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log id: 2974875