Effects of Troglitazone (CS-045) on insulin secretion in isolated rat pancreatic islets and HIT cells: an insulinotropic mechanism distinct from glibenclamide

scientific article published on January 1995

Effects of Troglitazone (CS-045) on insulin secretion in isolated rat pancreatic islets and HIT cells: an insulinotropic mechanism distinct from glibenclamide is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S001250050249
P698PubMed publication ID7744225

P2093author name stringS Kato
Y Seino
H Ishida
K Tsuda
T Miura
K Masuda
H Horikoshi
Y Okamoto
Y Tsuura
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Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty ratsQ38346193
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Effect of new oral antidiabetic agent CS-045 on glucose tolerance and insulin secretion in patients with NIDDM.Q51608769
Monolayer cultures of adult pancreatic islet cells on osmotically disrupted fibroblasts.Q52504240
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Role of cytosolic Ca2+ in impaired sensitivity to glucose of rat pancreatic islets exposed to high glucose in vitroQ67589791
Characterization of CS-045, a new oral antidiabetic agent, II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57BL/KsJ-db/db miceQ68047811
Impaired glucose sensitivity of ATP-sensitive K+ channels in pancreatic beta-cells in streptozotocin-induced NIDDM ratsQ68169138
Increased liver glucose-transporter protein and mRNA in streptozocin-induced diabetic ratsQ68499363
The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cellsQ69010313
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Characteristic features of insulin secretion in the streptozotocin-induced NIDDM rat modelQ70222841
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Suppressive effects of polygonati rhizoma on hepatic glucose output, GLUT2 mRNA expression and its protein content in rat liverQ72782591
Disopyramide blocks pancreatic ATP-sensitive K+ channels and enhances insulin releaseQ72917343
P433issue1
P304page(s)24-30
P577publication date1995-01-01
P1433published inDiabetologiaQ5270140
P1476titleEffects of Troglitazone (CS-045) on insulin secretion in isolated rat pancreatic islets and HIT cells: an insulinotropic mechanism distinct from glibenclamide
P478volume38

Reverse relations

cites work (P2860)
Q42523561Acute and chronic effects of troglitazone (CS-045) on isolated rat ventricular cardiomyocytes
Q37141727Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus
Q42512444Effects of high-dose troglitaz one on insulin sensitivity and beta-cell function in Watanabe heritable hyperlipidemic rabbits
Q35047497Expression and functional activity of PPARgamma in pancreatic beta cells
Q37577126In vivo actions of peroxisome proliferator-activated receptors: glycemic control, insulin sensitivity, and insulin secretion
Q34962291Insulin resistance, diabetes, and atherosclerosis: thiazolidinediones as therapeutic interventions
Q46050871Insulin-dependent actions of pioglitazone in newly diagnosed, drug naïve patients with type 2 diabetes
Q37577162Pathophysiologic approach to therapy in patients with newly diagnosed type 2 diabetes
Q36068458Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity.
Q35989381Potential role of oral thiazolidinedione therapy in preserving beta-cell function in type 2 diabetes mellitus
Q51556166Rosiglitazone taken once daily provides effective glycaemic control in patients with Type 2 diabetes mellitus.
Q39862439Serine-385 phosphorylation of inwardly rectifying K+ channel subunit (Kir6.2) by AMP-dependent protein kinase plays a key role in rosiglitazone-induced closure of the K(ATP) channel and insulin secretion in rats.
Q39748018Suppression effects of AICAR on insulin secretion involved in peroxisome proliferator-activated receptor gamma changes in INS-1 cells.
Q37138791The effects of Leptin and Adiponectin on Pdx1, Foxm1, and PPARγ Transcription in Rat Islets of Langerhans
Q33607634Thiazolidinediones: a new class of antidiabetic drugs
Q41521276Troglitazone

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