The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities.

scientific article published on July 1994

The FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities. is …
instance of (P31):
scholarly articleQ13442814

External links are
P698PubMed publication ID7517940

P2093author name stringThompson CB
Yang H
Mao X
Leiden JM
Miesfeldt S
P433issue27
P407language of work or nameEnglishQ1860
P304page(s)18216-18222
P577publication date1994-07-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe FLI-1 and chimeric EWS-FLI-1 oncoproteins display similar DNA binding specificities
P478volume269

Reverse relations

cites work (P2860)
Q24646455A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland
Q39658956Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors
Q42804345Cooperative DNA binding with AP-1 proteins is required for transformation by EWS-Ets fusion proteins
Q36560535Determinants of DNA-binding specificity of ETS-domain transcription factors
Q35620499Differentiation of carbon dioxide-sensing neurons in Caenorhabditis elegans requires the ETS-5 transcription factor
Q37362452EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells
Q33638434EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo
Q28307320Ecteinascidin 743 interferes with the activity of EWS-FLI1 in Ewing sarcoma cells
Q42801552Efficacy of siRNA nanocapsules targeted against the EWS-Fli1 oncogene in Ewing sarcoma.
Q34109415Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma
Q28506247Ets factors and a newly identified polymorphism regulate Fli1 promoter activity in lymphocytes
Q37397291Ewing sarcoma fusion protein EWSR1/FLI1 interacts with EWSR1 leading to mitotic defects in zebrafish embryos and human cell lines
Q37993924Ewing sarcoma/peripheral primitive neuroectodermal tumor and related tumors.
Q35057457Ewing's sarcoma: diagnostic, prognostic, and therapeutic implications of molecular abnormalities
Q24517781Fli-1, an Ets-related transcription factor, regulates erythropoietin-induced erythroid proliferation and differentiation: evidence for direct transcriptional repression of the Rb gene during differentiation
Q37152828GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.
Q35917053Genome-wide analyses reveal properties of redundant and specific promoter occupancy within the ETS gene family
Q37872764Genomic and biochemical insights into the specificity of ETS transcription factors
Q40016977Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis
Q46131586Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma
Q36365913Importance of low affinity Elf-1 sites in the regulation of lymphoid-specific inducible gene expression
Q41141104Inhibition of EWS-FLI-1 fusion protein with antisense oligodeoxynucleotides
Q35158848Kinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters
Q36786777Microsatellites as EWS/FLI response elements in Ewing's sarcoma
Q41887497Microsatellites with macro-influence in ewing sarcoma
Q36673885Molecular alterations in pediatric sarcomas: potential targets for immunotherapy
Q33963039Negative and translation termination-dependent positive control of FLI-1 protein synthesis by conserved overlapping 5' upstream open reading frames in Fli-1 mRNA.
Q37272420Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer
Q39237435Potential downstream target genes of aberrant ETS transcription factors are differentially affected in Ewing's sarcoma and prostate carcinoma.
Q38612055Progress in the molecular biology of ewing tumors.
Q35188770Promiscuous partnerships in Ewing's sarcoma
Q36287019RNA:DNA hybrids in the human genome have distinctive nucleotide characteristics, chromatin composition, and transcriptional relationships.
Q36562720Recent advances in the molecular pathogenesis of Ewing's sarcoma
Q34990559Reducing FLI1 levels in the MRL/lpr lupus mouse model impacts T cell function by modulating glycosphingolipid metabolism
Q38605150Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth
Q24546126SRE elements are binding sites for the fusion protein EWS-FLI-1
Q37305155The impact of Fli1 deficiency on the pathogenesis of systemic sclerosis
Q33420364The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation function
Q35927957The secondary structure of the ets domain of human Fli-1 resembles that of the helix-turn-helix DNA-binding motif of the Escherichia coli catabolite gene activator protein.
Q36825143The transcription factor Fli-1 modulates marginal zone and follicular B cell development in mice
Q33391783Thrombocytopenia in Mice Lacking the Carboxy-Terminal Regulatory Domain of the Ets Transcription Factor Fli1
Q38293060Transactivation of the Moloney murine leukemia virus and T-cell receptor beta-chain enhancers by cbf and ets requires intact binding sites for both proteins

Search more.