The platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion

scientific article published on June 2010

The platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/BI100541T
P932PMC publication ID2892908
P698PubMed publication ID20429610
P5875ResearchGate publication ID43353574

P2093author name stringJames R Dilks
Robert Flaumenhaft
Kamil Woronowicz
Price S Blair
Christian G Peters
Nataliya Rozenvayn
Louisa Dowal
Lucyna Woronowicz
P2860cites workIdentification of a cellubrevin/vesicle associated membrane protein 3 homologue in human plateletsQ22008648
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Myosin Va transports dense core secretory vesicles in pancreatic MIN6 beta-cellsQ28589310
Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregationQ28646199
SNAREs--engines for membrane fusionQ29547230
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The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretionQ45238856
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Stabilization of exocytosis by dynamic F-actin coating of zymogen granules in pancreatic aciniQ47377644
Distinct effect of actin cytoskeleton disassembly on exo- and endocytic events in a membrane patch of rat melanotrophsQ48425692
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Cdc42-dependent actin polymerization during compensatory endocytosis in Xenopus eggsQ48824757
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The actin cytoskeleton regulates exocytosis of all neutrophil granule subsets.Q52575996
Subcellular distribution of 3 functional platelet SNARE proteins: human cellubrevin, SNAP-23, and syntaxin 2.Q53873688
Molecular Mechanisms of Platelet Exocytosis: Requirements for α-Granule ReleaseQ58413600
Pancreatic Beta-Cell Web: Its Possible Role in Insulin SecretionQ69159303
In vitro reconstitution of chromaffin granule-cytoskeleton interactions: ionic factors influencing the association of F-actin with purified chromaffin granule membranesQ70312532
Association of actin with chromaffin granule membranes and the effect of cytochalasin B on the polarity of actin filament elongationQ71853423
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New anti-actin drugs in the study of the organization and function of the actin cytoskeletonQ73042577
Docked secretory vesicles undergo Ca2+-activated exocytosis in a cell-free systemQ73363105
Molecular mechanisms of platelet exocytosis: role of SNAP-23 and syntaxin 2 in dense core granule releaseQ73386728
Actin assembly induced by polylysine beads or purified phagosomes: quantitation by a new flow cytometry assayQ74173214
Alpha-granule secretion from alpha-toxin permeabilized, MgATP-exposed platelets is induced independently by H+ and Ca2+Q74614666
Interaction of syntaxin with alpha-fodrin, a major component of the submembranous cytoskeletonQ74630610
Proteins of the exocytotic core complex mediate platelet alpha-granule secretion. Roles of vesicle-associated membrane protein, SNAP-23, and syntaxin 4Q77801139
SNARE protein degradation upon platelet activation: calpain cleaves SNAP-23Q78696375
Stimulation of actin polymerization by vacuoles via Cdc42p-dependent signalingQ80860112
Protein phosphorylation and platelet secretionQ93638257
Cdc42 and actin control polarized expression of TI-VAMP vesicles to neuronal growth cones and their fusion with the plasma membrane.Q30476863
Intersectin-1L nucleotide exchange factor regulates secretory granule exocytosis by activating Cdc42Q30477783
Control of local actin assembly by membrane fusion-dependent compartment mixingQ30640323
Effects of latrunculin reveal requirements for the actin cytoskeleton during secretion from mast cellsQ31736913
Platelets possess and require an active protein palmitoylation pathway for agonist-mediated activation and in vivo thrombus formationQ33274055
Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivoQ33435199
Reconstitution of regulated exocytosis in cell-free systems: a critical appraisalQ33547274
Phosphatidylinositol 4,5-bisphosphate stimulates vesicle formation from liposomes by brain cytosolQ34014674
Adducin in platelets: activation-induced phosphorylation by PKC and proteolysis by calpainQ34118592
Endogenous plasma membrane t-SNARE syntaxin 4 is present in rab11 positive endosomal membranes and associates with cortical actin cytoskeleton.Q34159324
Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretionQ34168003
Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D.Q35004612
Actin remodeling to facilitate membrane fusionQ35197991
Endobrevin/VAMP-8 is the primary v-SNARE for the platelet release reactionQ35545284
Coupling actin and membrane dynamics during calcium-regulated exocytosis: a role for Rho and ARF GTPases.Q35979553
SNAP-23 and syntaxin-2 localize to the extracellular surface of the platelet plasma membraneQ35989495
Actin filament content and organization in unstimulated plateletsQ36209837
Identification of a membrane skeleton in plateletsQ36218510
Functional dissection of COP-I subunits in the biogenesis of multivesicular endosomesQ36274983
Hierarchy of protein assembly at the vertex ring domain for yeast vacuole docking and fusionQ36322950
α-Adducin dissociates from F-actin and spectrin during platelet activationQ36323516
Remodeling of organelle-bound actin is required for yeast vacuole fusionQ36325643
Actin filament disassembly is a sufficient final trigger for exocytosis in nonexcitable cellsQ36382464
Filamentous actin regulates insulin exocytosis through direct interaction with Syntaxin 4.Q36647975
Centripetal myosin redistribution in thrombin-stimulated platelets. Relationship to platelet Factor 4 secretionQ38521390
ATP-dependent membrane assembly of F-actin facilitates membrane fusionQ38670988
Phosphoinositides regulate membrane-dependent actin assembly by latex bead phagosomesQ39540596
Mechanisms of secretion from adrenal chromaffin cellsQ40117332
Role of actin cortex in the subplasmalemmal transport of secretory granules in PC-12 cells.Q40164543
Involvement of ezrin/moesin in de novo actin assembly on phagosomal membranesQ40386859
Recent advances in platelet structural physiologyQ40463068
A cell-free system for regulated exocytosis in PC12 cellsQ40903792
In vitro fusion of phagosomes with different endocytic organelles from J774 macrophages.Q40996848
Evidence for ADP-ribosylation factor (ARF) as a regulator of in vitro endosome-endosome fusion.Q41618601
A specific interaction in vitro between pancreatic zymogen granules and plasma membranes: stimulation by G-protein activators but not by Ca2+.Q41811791
Cortical filamentous actin disassembly and scinderin redistribution during chromaffin cell stimulation precede exocytosis, a phenomenon not exhibited by gelsolinQ41873803
Dynamic regulation of the large exocytotic fusion pore in pancreatic acinar cellsQ42412601
Selective assay of monomeric and filamentous actin in cell extracts, using inhibition of deoxyribonuclease I.Q43462070
Phosphatidylinositol 4,5-bisphosphate mediates Ca2+-induced platelet alpha-granule secretion: evidence for type II phosphatidylinositol 5-phosphate 4-kinase functionQ43576545
Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complexQ44294738
P4510describes a project that usesImageJQ1659584
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectcytoskeletonQ154626
P1104number of pages10
P304page(s)4533-4542
P577publication date2010-06-01
P1433published inBiochemistryQ764876
P1476titleThe platelet actin cytoskeleton associates with SNAREs and participates in alpha-granule secretion
P478volume49

Reverse relations

cites work (P2860)
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Q90171691Differential sensitivity of various markers of platelet activation with adenosine diphosphate
Q39207341Exocytosis proteins as novel targets for diabetes prevention and/or remediation?
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Q27026733Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells
Q58549008Small GTPases in platelet membrane trafficking
Q35904952VAMP-7 links granule exocytosis to actin reorganization during platelet activation

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