Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver

scientific article published on May 1987

Cytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.104.5.1207
P8608Fatcat IDrelease_llzqzzxccrdgbcg6f42oodsnxu
P932PMC publication ID2114456
P698PubMed publication ID3106362
P5875ResearchGate publication ID247533700

P2093author name stringYamamoto A
Masaki R
Tashiro Y
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
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Distribution and induction of cytochrome P-450 in rat liver nuclear envelopeQ36205456
Cytochrome P -450 synthesis in vivo and in a cell-free system from rat liverQ40898909
Phenobarbital-induced synthesis of the microsomal drug-metabolizing enzyme system and its relationship to the proliferation of endoplasmic membranes. A morphological and biochemical studyQ41068536
Is cytochrome P-450 transported from the endoplasmic reticulum to the Golgi apparatus in rat hepatocytes?Q41492105
Cathepsin D of rat spleen. Affinity purification and properties of two types of cathepsin DQ41621384
Quantitative immunoelectron-microscopic analyses of the distribution of cytochrome P-450 molecules on rat liver microsomesQ41687352
Some properties of a detergent-solubilized NADPH-cytochrome c(cytochrome P-450) reductase purified by biospecific affinity chromatographyQ43575776
Isolation and characterization of autolysosomes which appeared in rat liver after leupeptin treatment.Q52504931
Effects of phenobarbital on the synthesis and degradation of the protein components of rat liver microsomal membranes.Q53986486
The in vivo turnover of rat liver microsomal epoxide hydrolase and both the apoprotein and heme moieties of specific cytochrome P-450 isozymesQ64764696
Effect of phenobarbital administration to rats on the level of the in vitro synthesis of cytochrome P-450 directed by total rat liver RNAQ66955000
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The turnover of microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase in the livers of mice treated with phenobarbitalQ68718987
A new method for simultaneous purification of cytochrome b5 and NADPH-cytochrome c reductase from rat liver microsomesQ68743785
Identification and quantification of a messenger ribonucleic acid induced by polynuclear aromatic hydrocarbons--using a cloned human cytochrome P-450 geneQ69803933
A biochemical and electron microscopic study of changes in the content of cytochrome P-450 in rat livers after cessation of treatment with phenobarbital, .BETA.-naphtoflavone or 3-methylcholanthreneQ70352857
Turnover of two drug-inducible forms of microsomal cytochrome P-450 in rat liverQ70445272
Turnover of membrane proteins: kinetics of induction and degradation of seven forms of rat liver microsomal cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydrolaseQ70504871
Studies on the biosynthesis of microsomal membrane proteins. Site of synthesis and mode of insertion of cytochrome b5, cytochrome b5 reductase, cytochrome P-450 reductase and epoxide hydrolaseQ71589331
Cloning of DNA complementary to rat liver NADPH-cytochrome c (P-450) oxidoreductase and cytochrome P-450b mRNAs. Evidence that phenobarbital augments transcription of specific genesQ71596471
Mechanism of induction of cytochrome P-450 by phenobarbitalQ72498808
Sequestration of cytoplasmic enzymes in an autophagic vacuole-lysosomal system induced by injection of leupeptinQ72553220
P433issue5
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)1207-1215
P577publication date1987-05-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleCytochrome P-450 and NADPH-cytochrome P-450 reductase are degraded in the autolysosomes in rat liver
P478volume104

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