Molecular biology of glycinergic neurotransmission

scientific article published on June 1997

Molecular biology of glycinergic neurotransmission is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1001106865
P356DOI10.1007/BF02740653
P698PubMed publication ID9294860

P50authorFrancisco ZafraQ40071653
Cecilio GiménezQ40071693
P2093author name stringAragón C
P2860cites workExpression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporterQ24296225
Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genesQ24301903
Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localizationQ24308791
Cloning of the human glycine transporter type 1: molecular and pharmacological characterization of novel isoform variants and chromosomal localization of the gene in the human and mouse genomesQ24313513
Functional identification of a vesicular acetylcholine transporter and its expression from a "cholinergic" gene locusQ24318365
A missense mutation in the gene encoding the alpha 1 subunit of the inhibitory glycine receptor in the spasmodic mouseQ24321378
Mutations in the alpha 1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexiaQ24336984
Expression cloning of a reserpine-sensitive vesicular monoamine transporterQ24563187
Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexiaQ24568268
Heteromeric NMDA receptors: molecular and functional distinction of subtypesQ28182183
Evidence for recessive as well as dominant forms of startle disease (hyperekplexia) caused by mutations in the alpha 1 subunit of the inhibitory glycine receptorQ28235848
Phosphorylation of the 48-kDa subunit of the glycine receptor by protein kinase CQ28279112
Identification of a gephyrin binding motif on the glycine receptor beta subunitQ28288546
Glycine immunoreactivity localized in the cochlear nucleus and superior olivary complexQ28302911
Isolation and sequence determination of cDNA clones for porcine and human lipoamide dehydrogenase. Homology to other disulfide oxidoreductasesQ28303197
Purification of the sodium- and chloride-coupled glycine transporter from central nervous system.Q43720774
GABA release triggered by the activation of neuron-like non-NMDA receptors in cultured type 2 astrocytes is carrier-mediatedQ44207110
Two distinct mechanisms, differentially affected by excitatory amino acids, trigger GABA release from fetal mouse striatal neurons in primary cultureQ44211557
Neither amino nor carboxyl termini are required for function of the sodium- and chloride-coupled gamma-aminobutyric acid transporter from rat brainQ45134997
Glycine, glycinamide and D-serine act as positive modulators of signal transduction at the N-methyl-D-aspartate (NMDA) receptor in vivo: differential effects on mouse cerebellar cyclic guanosine monophosphate levelsQ45155972
Recognition domains in assembly of oligomeric membrane proteinsQ45287517
In vivo modulation of N-methyl-D-aspartate receptor-dependent long-term potentiation by the glycine modulatory siteQ45307362
Zinc potentiates agonist-lnduced currents at certain splice variants of the NMDA receptorQ45975434
Localization of glycine receptors in the rat central nervous system: an immunocytochemical analysis using monoclonal antibodyQ46069849
The Caenorhabditis elegans unc-17 gene: a putative vesicular acetylcholine transporterQ47069001
The spastic mouse: aberrant splicing of glycine receptor beta subunit mRNA caused by intronic insertion of L1 elementQ48078656
Glycine receptor beta-subunit gene mutation in spastic mouse associated with LINE-1 element insertion.Q48082303
Modulation of glycine affinity for NMDA receptors by extracellular Ca2+ in trigeminal neurons.Q48093520
Down-regulation of glycine receptor channels by protein kinase C in Xenopus oocytes injected with synthetic RNA.Q48102518
Structural analysis and functional role of the carbohydrate component of glycine transporter.Q48104905
Glycine-like immunoreactivity in the rat auditory pathwayQ48110614
A rat brain cDNA encoding the neurotransmitter transporter with an unusual structureQ48137661
Modulation of inhibitory glycine receptors by phosphorylation by protein kinase C and cAMP-dependent protein kinaseQ48188755
Glycine-like immunoreactivity in the cerebellum of rat and Senegalese baboon, Papio papio: a comparison with the distribution of GABA-like immunoreactivity and with [3H]glycine and [3H]GABA uptakeQ48231389
Characterization of glycine uptake in plasma membrane vesicles isolated from cultured glioblastoma cellsQ48277267
Glycine neurons in the brain and spinal cord. Antibody production and immunocytochemical localizationQ48331756
Hydrodynamic properties and immunological identification of the sodium- and chloride-coupled glycine transporter.Q48344737
Immunocytochemical localization of amino acid neurotransmitter candidates in the ventral horn of the cat spinal cord: a light microscopic studyQ48389076
Immunocytochemical demonstration of glycine in retinaQ48428532
3Hglycine uptake in rat hippocampus: kinetic analysis and autoradiographic localizationQ48528789
Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat.Q48531061
Hippocampal slices of kindled rats reveal calcium involvement in epileptogenesisQ48580512
Glycine cleavage system in astrocytesQ48609830
Glycine receptor immunoreactivity in rat and human cerebral cortexQ48640666
Activation of high-affinity uptake of glutamate by phorbol esters in primary glial cell culturesQ48651287
Release of endogenous Zn2+ from brain tissue during activityQ48682530
GABA and glycine in synaptic vesicles: storage and transport characteristicsQ48685092
Nonketotic Hyperglycinemia: Two Patients with Primary Defects of P-Protein and T-Protein, Respectively, in the Glycine Cleavage SystemQ48711296
High affinity uptake systems for glycine, glutamic and aspaspartic acids in synaptosomes of rat central nervous tissuesQ48741011
Localization of glycine receptor alpha 1 subunit mRNA-containing neurons in the rat brain: an analysis using in situ hybridization histochemistryQ48830344
Non-vesicular release of glutamate from glial cells by reversed electrogenic glutamate uptakeQ48857498
Modulation of glycine receptor chloride channels by cAMP-dependent protein kinase in spinal trigeminal neuronsQ48859059
Uptake of glycine into synaptic vesicles isolated from rat spinal cordQ49036448
Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptorsQ49060987
Energy dependence and functional reconstitution of the gamma-aminobutyric acid carrier from synaptic vesiclesQ49104794
Glycine-glutamate interactions at the NMDA receptor: role of cysteine residuesQ49124802
Preferential co-assembly of recombinant NMDA receptors composed of three different subunitsQ49132933
Functional correlation of fetal and adult forms of glycine receptors with developmental changes in inhibitory synaptic receptor channelsQ49161290
A single amino acid exchange alters the pharmacology of neonatal rat glycine receptor subunit.Q50803232
Glycine uptake in rat central nervous system slices and homogenates: evidence for different uptake systems in spinal cord and cerebral cortex.Q51120514
A pharmacological study of the depression of spinal neurones by glycine and related amino acids.Q51193298
Biphasic modulation of the strychnine-sensitive glycine receptor by Zn2+.Q51618943
Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS.Q52208167
A novel modulatory binding site for zinc on the GABAA receptor complex in cultured rat neuronesQ52233054
Inhibition of motoneurones by iontophoresis of glycine.Q53813566
Efflux and exchange of glycine by plasma membrane vesicles isolated from glioblastoma cells.Q55485851
Glycine potentiates the NMDA response in cultured mouse brain neuronsQ59050531
Activation of multiple-conductance state chloride channels in spinal neurones by glycine and GABAQ59069378
Uptake of 14C Glycine by Spinal CordQ59074948
Hippocampal GABA transporter function in temporal-lobe epilepsyQ59093542
Photoaffinity-labelling of the glycine receptor of rat spinal cordQ67285001
Glutamate, GABA, and glycine in the human retina: an immunocytochemical investigationQ68328516
Localization of the strychnine binding site on the 48-kilodalton subunit of the glycine receptorQ68482578
Synaptic physiology of spinal motoneurones of normal and spastic mice: an in vitro studyQ68966864
Depolarization without calcium can release gamma-aminobutyric acid from a retinal neuronQ69006380
Colocalization of glycine-like and GABA-like immunoreactivities in Golgi cell terminals in the rat cerebellum: a postembedding light and electron microscopic studyQ69034206
Modulation of NMDA receptor-mediated responses by glycine and D-serine in the rat thalamus in vivoQ69348428
Primary cultures of mouse spinal cord express the neonatal isoform of the inhibitory glycine receptorQ69366000
Stoichiometry of sodium- and chloride-coupled glycine transport in synaptic plasma membrane vesicles derived from rat brainQ69721073
Glycine receptor immunoreactivity in the ventral cochlear nucleus of the guinea pigQ69843490
The Mr 93,000 polypeptide of the postsynaptic glycine receptor complex is a peripheral membrane proteinQ70173673
The release of gamma-aminobutyric acid from horizontal cells of the goldfish (Carassius auratus) retinaQ70389954
Depolarization-induced release of glycine and beta-alanine from plasma membrane vesicles derived from rat brain synaptosomesQ70392717
Colocalization of GABA, glycine, and their receptors at synapses in the rat spinal cordQ70891485
Calcium-independent release of GABA from isolated horizontal cells of the toad retinaQ71610681
Analysis of the transmembrane topology of the glycine transporter GLYT1Q71973709
Amino acid neurotransmitter transporters: structure, function, and molecular diversityQ72227677
Modulation of hippocampal glycine receptor channels by protein kinase CQ72252358
The postsynaptic localization of the glycine receptor-associated protein gephyrin is regulated by the cytoskeletonQ72334874
Carrier-mediated release of GABA from retinal horizontal cellsQ72550349
Localization of glycine neurotransmitter transporter (GLYT2) reveals correlation with the distribution of glycine receptorQ72557641
Immunocytochemical localization of glycine receptors in the mammalian retinaQ72573099
Agonist response kinetics of N-methyl-D-aspartate receptors in neurons cultured from rat cerebral cortex and cerebellum: evidence for receptor heterogeneityQ72660953
Glycine receptors: a startling connectionQ72751014
Purification by affinity chromatography of the glycine receptor of rat spinal cordQ72940488
Glycine receptor: light microscopic autoradiographic localization with [3H]strychnineQ72941178
An ultrastructural study of the glycine transporter GLYT2 and its association with glycine in the superficial laminae of the rat spinal dorsal hornQ74210734
The 93-kDa glycine receptor-associated protein binds to tubulinQ28304856
The atypical M2 segment of the beta subunit confers picrotoxinin resistance to inhibitory glycine receptor channelsQ28316466
Cyanotriphenylborate: subtype-specific blocker of glycine receptor chloride channelsQ28369450
Residues within transmembrane segment M2 determine chloride conductance of glycine receptor homo- and hetero-oligomersQ28378647
Point mutation of glycine receptor alpha 1 subunit in the spasmodic mouse affects agonist responsesQ28505212
Glycine receptor alteration in the mutant mouse spasticQ28505662
Cloning and expression of a glycine transporter reveal colocalization with NMDA receptorsQ28565322
Cloning and expression of a rat brain GABA transporterQ28566313
Alternative splicing generates two variants of the alpha 1 subunit of the inhibitory glycine receptorQ28573468
Identification and functional expression of a novel ligand binding subunit of the inhibitory glycine receptorQ28573573
Alternative splicing generates two isoforms of the alpha 2 subunit of the inhibitory glycine receptorQ28577372
Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural featuresQ28580711
A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporterQ28581165
Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteinsQ28581418
Low level expression of glycine receptor beta subunit transgene is sufficient for phenotype correction in spastic miceQ28584786
A frameshift mutation in the mouse alpha 1 glycine receptor gene (Glra1) results in progressive neurological symptoms and juvenile deathQ28594798
The glycine cleavage system. Molecular cloning of the chicken and human glycine decarboxylase cDNAs and some characteristics involved in the deduced protein structuresQ28610511
Molecular diversity of glutamate receptors and implications for brain functionQ28611078
Modulation of seizure susceptibility in the mouse by the strychnine-insensitive glycine recognition site of the NMDA receptor/ion channel complexQ30498832
Neurotransmitter transporter family cDNAs in a rat midbrain library: 'orphan transporters' suggest sizable structural variationsQ30813364
Molecular cloning of a cDNA encoding chicken T-protein of the glycine cleavage system and expression of the functional protein in Escherichia coli. Effect of mRNA secondary structure in the translational initiation region on expressionQ31098003
Functional expression in Xenopus oocytes of the strychnine binding 48 kd subunit of the glycine receptor.Q33560688
Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamerQ33653057
Active transport of gamma-aminobutyric acid and glycine into synaptic vesiclesQ33859552
Cloning and expression of the 58 kd beta subunit of the inhibitory glycine receptorQ33919478
Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytesQ34048105
The mitochondrial glycine cleavage system. Functional association of glycine decarboxylase and aminomethyl carrier proteinQ34057522
Structural analysis of mouse glycine receptor alpha subunit genes. Identification and chromosomal localization of a novel variantQ34291061
The role of N-glycosylation in the targeting and activity of the GLYT1 glycine transporterQ34308897
Evolutionary relationships among pyridoxal-5'-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma familiesQ34336063
Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometryQ34347246
Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common geneQ34365117
Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat.Q34667685
Molecular cloning and characterization of the rat NMDA receptorQ34762781
Transporter explosion: update on uptakeQ35206066
Molecular Neurobiology of Glutamate ReceptorsQ35227054
External Ca(2+)-independent release of neurotransmittersQ35249921
Molecular cloning of a putative vesicular transporter for acetylcholineQ35865884
Distribution of glycine receptors at central synapses: an immunoelectron microscopy studyQ36212545
Glycine and glycine receptor immunoreactivity in brain and spinal cordQ36415783
Amino acid neurotransmission: spotlight on synaptic vesiclesQ36570724
Homology and analogy in transmembrane channel design: lessons from synaptic membrane proteinsQ36574660
Regulation of neurotransmitter receptor desensitization by protein phosphorylationQ36601305
Cellular expression of glycine transporter 2 messenger RNA exclusively in rat hindbrain and spinal cordQ36698201
A new family of neurotransmitter transporters: the high-affinity glutamate transportersQ36721193
Cloning and expression of the vesamicol binding protein from the marine ray Torpedo. Homology with the putative vesicular acetylcholine transporter UNC-17 from Caenorhabditis elegansQ36745944
Cloning, expression, and localization of a rat brain high-affinity glycine transporterQ37139339
The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.Q37569543
The unique extracellular disulfide loop of the glycine receptor is a principal ligand binding elementQ37619407
Synaptosomal transport: a chloride dependence for choline, GABA, glycine and several other compoundsQ39201240
Glycine transporters are differentially expressed among CNS cells.Q39757615
Gephyrin antisense oligonucleotides prevent glycine receptor clustering in spinal neurons.Q39757798
Functional architecture of the nicotinic acetylcholine receptor: a prototype of ligand-gated ion channelsQ40386612
Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanismsQ40396457
Neurotransmitter action: Opening of ligand-gated ion channelsQ40484741
Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticityQ40486109
Structure, diversity and synaptic localization of inhibitory glycine receptorsQ40603065
Neural degeneration and the transport of neurotransmittersQ40618637
Presynaptic events involved in neurotransmissionQ40621816
The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potentialQ40649282
Neurotransmitter transporters: recent progressQ40708857
Nonvesicular release of neurotransmitter.Q40713047
The glycine site of the NMDA receptor--five years on.Q40851783
Widespread expression of glycine receptor subunit mRNAs in the adult and developing rat brainQ41081995
Enhancement of NMDA-evoked neuronal activity by glycine in the rat spinal cord in vivoQ41127036
Recombinant human NMDA homomeric NR1 receptors expressed in mammalian cells form a high-affinity glycine antagonist binding siteQ41373489
Regulation by phorbol esters of the glycine transporter (GLYT1) in glioblastoma cellsQ41379110
Mutation of an arginine residue in the human glycine receptor transforms beta-alanine and taurine from agonists into competitive antagonistsQ41391248
Carboxyl terminus of the glycine transporter GLYT1 is necessary for correct processing of the protein.Q41429437
Phosphorylation and modulation of brain glutamate transporters by protein kinase C.Q41508131
Agonist pharmacology of neonatal and adult glycine receptor alpha subunits: identification of amino acid residues involved in taurine activationQ41524934
Dual-component NMDA receptor currents at a single central synapse.Q41946065
Glycine transport into plasma-membrane vesicles derived from rat brain synaptosomesQ42165741
The glycine receptor deficiency of the mutant mouse spastic: evidence for normal glycine receptor structure and localization.Q42205821
The strychnine-binding subunit of the glycine receptor shows homology with nicotinic acetylcholine receptorsQ42206666
Mutations affecting the glycine receptor agonist transduction mechanism convert the competitive antagonist, picrotoxin, into an allosteric potentiator.Q42279580
Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents.Q42490310
Arachidonic acid inhibits glycine transport in cultured glial cellsQ42859081
Inhibition of high-affinity gamma-aminobutyric acid uptake in primary astrocyte cultures by phorbol esters and phospholipase C.Q42860012
P433issue3
P921main subjectmolecular biologyQ7202
P304page(s)117-142
P577publication date1997-06-01
P1433published inMolecular NeurobiologyQ15716645
P1476titleMolecular biology of glycinergic neurotransmission
P478volume14

Reverse relations

cites work (P2860)
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