The cryo-electron microscopy structure of human transcription factor IIH.

scientific article published on 13 September 2017

The cryo-electron microscopy structure of human transcription factor IIH. is …
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P6179Dimensions Publication ID1091602147
P356DOI10.1038/NATURE23903
P932PMC publication ID5844561
P698PubMed publication ID28902838

P50authorEva NogalesQ4795157
Basil J. GreberQ38362078
Pavel V AfonineQ89000648
P2093author name stringPaul D Adams
Jie Fang
Thi Hoang Duong Nguyen
P2860cites workA yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIHQ24291428
Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repairQ24304166
SF1 and SF2 helicases: family mattersQ24596016
XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutationsQ24603061
Subunit architecture of general transcription factor TFIIHQ24633293
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Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactionsQ24657441
Crystal structures of mismatch repair protein MutS and its complex with a substrate DNAQ27627633
Solution structure of the N-terminal domain of the human TFIIH MAT1 subunit: new insights into the RING finger familyQ27627771
Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophyQ27644020
Structure of the DNA Repair Helicase XPDQ27650710
Crystal Structure of the FeS Cluster–Containing Nucleotide Excision Repair Helicase XPDQ27650943
Structural basis for group A trichothiodystrophyQ27653533
A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA exportQ27667333
Functional and structural studies of the nucleotide excision repair helicase XPD suggest a polarity for DNA translocationQ27675554
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.Q27677990
Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the RibosomeQ27683626
A structure-specific nucleic acid-binding domain conserved among DNA repair proteinsQ27683756
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The Structure of the TFIIH p34 Subunit Reveals a Von Willebrand Factor A Like FoldQ27684656
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Function of Conserved Topological Regions within the Saccharomyces cerevisiae Basal Transcription Factor TFIIHQ27930595
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Double-stranded DNA translocase activity of transcription factor TFIIH and the mechanism of RNA polymerase II open complex formationQ27939771
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A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophyQ28142117
Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54Q28243168
A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group AQ28268795
Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIHQ28285305
Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repairQ28306198
Molecular structure of human TFIIHQ28611504
A summary of mutations in the UV-sensitive disorders: Xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophyQ29014018
X-Ray Structures of the Sulfolobus solfataricus SWI2/SNF2 ATPase Core and Its Complex with DNAQ29400687
Optimal determination of particle orientation, absolute hand, and contrast loss in single-particle electron cryomicroscopyQ29547579
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Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIHQ33285675
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In TFIIH, XPD helicase is exclusively devoted to DNA repairQ34275749
Structural visualization of key steps in human transcription initiationQ34330132
Crystal structure of the Rad3/XPD regulatory domain of Ssl1/p44.Q35221571
Sampling the conformational space of the catalytic subunit of human γ-secretaseQ36479662
ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activitiesQ36637485
Mechanism of DNA loading by the DNA repair helicase XPD.Q36775572
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Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolutionQ38584680
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The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator functionQ42082510
Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patientsQ42443501
Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosomeQ46391372
CTFFIND4: Fast and accurate defocus estimation from electron micrographs.Q50866431
P433issue7672
P407language of work or nameEnglishQ1860
P921main subjectcryogenic electron microscopyQ5190506
P304page(s)414-417
P577publication date2017-09-13
P1433published inNatureQ180445
P1476titleThe cryo-electron microscopy structure of human transcription factor IIH.
P478volume549