MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage

scientific article published on September 2016

MALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2016.08.080
P932PMC publication ID5087334
P698PubMed publication ID27681433

P2093author name stringSimon C Watkins
Adrian T Ting
Dong Hu
John Bertin
Linda M McAllister-Lucas
Peter C Lucas
Shufang Gu
Kevin P Foley
Katherine I Oravecz-Wilson
Peter J Gough
Danielle N Alfano
Vincent J Concel
Linda R Klei
Rachel E Bridwell
Kelly M Bailey
Phillip C Delekta
Matthew Van Beek
Emily M Hess
Robert Panek
P2860cites workCard10 is a novel caspase recruitment domain/membrane-associated guanylate kinase family member that interacts with BCL10 and activates NF-kappa BQ24290946
Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeletonQ24292682
CYLD regulates angiogenesis by mediating vascular endothelial cell migrationQ24301471
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20Q24307779
CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulinQ24314876
CARMA3/Bcl10/MALT1-dependent NF-kappaB activation mediates angiotensin II-responsive inflammatory signaling in nonimmune cellsQ24675332
Mechanisms regulating endothelial permeabilityQ26866511
Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspaseQ27685382
CYLD - a deubiquitylase that acts to fine-tune microtubule properties and functionsQ28072361
Bimp1, a MAGUK family member linking protein kinase C activation to Bcl10-mediated NF-kappaB inductionQ28198772
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaBQ28201706
Post-translational modifications regulate microtubule functionQ29036830
Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphataseQ29615195
Thrombin signalling and protease-activated receptorsQ29619601
Impedance analysis of GPCR-mediated changes in endothelial barrier function: overview and fundamental considerations for stable and reproducible measurementsQ30373402
The CARMA3-Bcl10-MALT1 signalosome promotes angiotensin II-dependent vascular inflammation and atherogenesisQ34074217
T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.Q34174201
The CARD11-BCL10-MALT1 (CBM) signalosome complex: Stepping into the limelight of human primary immunodeficiencyQ34206229
Malt1-dependent RelB cleavage promotes canonical NF-kappaB activation in lymphocytes and lymphoma cell lines.Q34211312
Cytoskeletal regulation of pulmonary vascular permeabilityQ34377340
Thrombin-dependent NF-{kappa}B activation and monocyte/endothelial adhesion are mediated by the CARMA3·Bcl10·MALT1 signalosomeQ34438768
Analysis of microtubule dynamic instability using a plus-end growth markerQ34547668
'Role reversal' for the receptor PAR1 in sepsis-induced vascular damageQ34686193
The proteolytic activity of the paracaspase MALT1 is key in T cell activationQ34748769
Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injuryQ35212825
RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock.Q35377560
Bcl10 and Malt1 control lysophosphatidic acid-induced NF-kappaB activation and cytokine productionQ35575886
Bcl10 plays a critical role in NF-kappaB activation induced by G protein-coupled receptors.Q35575890
MALT1 Protease Activity Is Required for Innate and Adaptive Immune ResponsesQ35597435
CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activationQ35741899
CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.Q35762426
Development of new Malt1 inhibitors and probes.Q35991775
Signaling mechanisms regulating endothelial permeabilityQ36350076
The roles of proteinase-activated receptors in the vascular physiology and pathophysiology.Q36649442
Microtubule-associated proteins as targets in cancer chemotherapyQ36823252
Genetic errors of the human caspase recruitment domain-B-cell lymphoma 10-mucosa-associated lymphoid tissue lymphoma-translocation gene 1 (CBM) complex: Molecular, immunologic, and clinical heterogeneityQ36973638
Role of the CARMA1/BCL10/MALT1 complex in lymphoid malignanciesQ36988095
CXCL8/IL8 stimulates vascular endothelial growth factor (VEGF) expression and the autocrine activation of VEGFR2 in endothelial cells by activating NFkappaB through the CBM (Carma3/Bcl10/Malt1) complexQ37112245
Regulation of endothelial junctional permeabilityQ37122803
Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturationQ37165388
Inflammation and plaque vulnerabilityQ37370224
CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processesQ37448141
CYLD regulates spindle orientation by stabilizing astral microtubules and promoting dishevelled-NuMA-dynein/dynactin complex formationQ37587645
CYLD coordinates with EB1 to regulate microtubule dynamics and cell migrationQ37698907
MALT1 small molecule inhibitors specifically suppress ABC-DLBCL in vitro and in vivoQ37699271
Atherosclerosis: current pathogenesis and therapeutic optionsQ37953777
Molecular mechanisms of de novo lumen formationQ38245882
MALT1--a universal soldier: multiple strategies to ensure NF-κB activation and target gene expressionQ38495157
Control of microtubule organization and dynamics: two ends in the limelightQ38631883
Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extensionQ38971296
Pharmacologic inhibition of MALT1 protease by phenothiazines as a therapeutic approach for the treatment of aggressive ABC-DLBCL.Q39226671
A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.Q39843043
A20 is a negative regulator of BCL10- and CARMA3-mediated activation of NF-kappaB.Q40001105
LIM kinase 1 coordinates microtubule stability and actin polymerization in human endothelial cellsQ40421769
Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca(2+) Signaling in Endothelial Cells.Q41531091
plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamicsQ42264953
GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunctionQ46781644
The tumor suppressor CYLD regulates microtubule dynamics and plays a role in cell migration.Q46789192
Microtubule depolymerization rapidly collapses capillary tube networks in vitro and angiogenic vessels in vivo through the small GTPase Rho.Q47292754
Evans blue dye as a marker of albumin clearance in cultured endothelial monolayer and isolated lungQ50795025
Finally, MALT1 is a protease!Q80733950
The acute respiratory distress syndromeQ84693193
P433issue1
P304page(s)221-232
P577publication date2016-09-01
P1433published inCell ReportsQ5058165
P1476titleMALT1 Protease Activation Triggers Acute Disruption of Endothelial Barrier Integrity via CYLD Cleavage
P478volume17