T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages

scientific article published on 29 July 2016

T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.201646440
P932PMC publication ID5183457
P698PubMed publication ID27469439

P50authorRichard J. HodesQ56755018
P2093author name stringY Jeffrey Chiang
P2860cites workLong-Term Survival But Impaired Homeostatic Proliferation of Naive T Cells in the Absence of p56lckQ57267865
pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cellsQ63226061
Inducible Expression of a p56Lck Transgene Reveals a Central Role for Lck in the Differentiation of CD4 SP ThymocytesQ64448638
Lck availability during thymic selection determines the recognition specificity of the T cell repertoireQ28298459
An efficient recombination system for chromosome engineering in Escherichia coliQ29615038
Adaptor proteins and T-cell antigen receptor signalingQ33650624
Regulation of T cell development by c-Cbl: essential role of Lck.Q35524069
Complex controls: the role of alternative promoters in mammalian genomesQ35571559
Developmental regulation of lck gene expression in T lymphocytesQ36229919
Structure of the murine lck gene and its rearrangement in a murine lymphoma cell lineQ36792522
Functional dissection of the lck proximal promoterQ36817536
Two lck transcripts containing different 5' untranslated regions are present in T cellsQ36925394
The functional consequences of alternative promoter use in mammalian genomesQ37105466
An overview on the generation of BAC transgenic mice for neuroscience researchQ37144517
The right team at the right time to go for a home run: tyrosine kinase activation by the TCR.Q37677539
Cbl-b regulates the CD28 dependence of T-cell activation.Q40904107
Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activityQ43513983
alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinasesQ46505598
Functional dissection of the murine lck distal promoterQ48071793
Requirement for tyrosine kinase p56lck for thymic development of transgenic gamma delta T cellsQ57185508
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)2401-2408
P577publication date2016-07-29
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleT-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages
P478volume46

Reverse relations

cites work (P2860)
Q58761812An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example
Q52668625Calnexin is necessary for T cell transmigration into the central nervous system.
Q38758780Myocardial ischemia/reperfusion injury: the role of adaptor proteins Crk.
Q28553440Proteomic Signatures of Thymomas
Q47165288Zinc Signals and Immunity
Q47256027Zinc as a Gatekeeper of Immune Function.

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