Partial purification and characterization of the lck protein-tyrosine kinase from bovine thymus

scientific article published on October 1991

Partial purification and characterization of the lck protein-tyrosine kinase from bovine thymus is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/BJ2790567
P932PMC publication ID1151641
P698PubMed publication ID1953650
P5875ResearchGate publication ID21201646

P2093author name stringQ M Wang
M L Harrison
R L Geahlen
P R Srinivas
P2860cites workCross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation siteQ24321802
Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applicationsQ24561689
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Characterization of four tyrosine protein kinases from the particulate fraction of rat spleenQ28296649
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lckQ28506433
Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lckQ28511623
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresisQ29547747
Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylationQ33580628
Mutation of a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine protein kinase, p56lck, reveals its oncogenic potential in fibroblastsQ33580738
Association of the fyn protein-tyrosine kinase with the T-cell antigen receptorQ33620349
Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src)Q35326726
Phosphorylation of synthetic peptides by a tyrosine protein kinase from the particulate fraction of a lymphoma cell lineQ36276081
Engagement of CD4 and CD8 expressed on immature thymocytes induces activation of intracellular tyrosine phosphorylation pathwaysQ36356927
Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virusQ36398185
Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck)Q36782472
Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activationQ36847174
Phosphorylation activates the insulin receptor tyrosine protein kinaseQ37613194
Affinity labeling of purine nucleotide sites in proteinsQ40137029
Immunochemical detection of adenine nucleotide-binding proteins with antibodies to 5'-p-fluorosulfonylbenzoyladenosineQ41718856
Stimulation of the antigen and interleukin-2 receptors on T lymphocytes activates distinct tyrosine protein kinasesQ41730679
Protein tyrosine phosphorylation associated with activation of the interleukin 2 receptorQ41737720
Increases in tyrosine phosphorylation are detectable before phospholipase C activation after T cell receptor stimulationQ41743311
Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagentQ42935742
Post-translational alterations of the tyrosine kinase p56lck in response to activators of protein kinase C.Q43793848
Purification and characterization of a cytosolic protein-tyrosine kinase from porcine spleenQ44046877
Analysis of the activity and phosphorylation of the lck protein in lymphoid cells.Q45074969
Expression of a new tyrosine protein kinase is stimulated by retrovirus promoter insertionQ48368270
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA.Q48373044
Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro.Q53552017
Generation of an active protein-tyrosine kinase from lymphocytes by proteolysisQ67980844
Activation of a tyrosine protein kinase is an early event in the stimulation of T lymphocytes by interleukin-2Q68093399
Synthesis and protein-tyrosine kinase inhibitory activities of flavonoid analoguesQ68199286
Characterization of partially purified cytosolic protein-tyrosine kinase from porcine spleenQ68388468
Identification of the human T-lymphocyte protein-tyrosine kinase by peptide-specific antibodiesQ68808682
Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptorQ68973514
Purification and characterization of a protein-tyrosine kinase from bovine thymusQ69663902
T cell activation induces rapid tyrosine phosphorylation of a limited number of cellular substratesQ69739741
Two-dimensional analysis of interleukin 2-regulated tyrosine kinase activation mediated by the p70-75 beta subunit of the interleukin 2 receptorQ69740990
Purification and characterization of a protein tyrosine kinase from bovine spleenQ69752866
Properties of a tyrosine protein kinase from calf thymus. Response to ionic strength and divalent cationsQ69867995
Identification of essential residues in the F1-ATPases by chemical modificationQ69933181
Affinity labeling of cAMP-dependent protein kinasesQ70176809
T and B lymphocytes express distinct tyrosine protein kinasesQ70368679
Purification and characterization of the major species of tyrosine protein kinase in rat liverQ70793621
A lymphoma cell line expressing elevated levels of tyrosine protein kinase activityQ70992208
P407language of work or nameEnglishQ1860
P304page(s)567-574
P577publication date1991-10-01
P1433published inBiochemical JournalQ864221
P1476titlePartial purification and characterization of the lck protein-tyrosine kinase from bovine thymus
P478volume279 ( Pt 2)

Reverse relations

cites work (P2860)
Q21284387Characterization of the interactions between the active site of a protein tyrosine kinase and a divalent metal activator
Q47779120From direct to indirect lithium targets: a comprehensive review of omics data.
Q41548349Purification and characterization of the major tyrosine protein kinase from the human promyelocytic cell line, HL60.
Q36421433The SH3 domain of Lck modulates T-cell receptor-dependent activation of extracellular signal-regulated kinase through activation of Raf-1.
Q28217304The oxygen-substituted palmitic acid analogue, 13-oxypalmitic acid, inhibits Lck localization to lipid rafts and T cell signaling
Q28296153The protein-tyrosine kinase Lck associates with and is phosphorylated by Cdc2
Q41613454p56lck stably associates with a 115 kDa substrate

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