| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1981PNAS...78.1624L |
| P356 | DOI | 10.1073/PNAS.78.3.1624 |
| P953 | full work available at URL | https://europepmc.org/articles/PMC319184 |
| https://europepmc.org/articles/PMC319184?pdf=render | ||
| https://pnas.org/doi/pdf/10.1073/pnas.78.3.1624 | ||
| P932 | PMC publication ID | 319184 |
| P698 | PubMed publication ID | 6262821 |
| P5875 | ResearchGate publication ID | 16933099 |
| P50 | author | J. Michael Bishop | Q311358 |
| P2093 | author name string | A. D. Levinson | |
| S. A. Courtneidge | |||
| P2860 | cites work | Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein | Q24297885 |
| Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src) | Q24597268 | ||
| Nucleotide sequence of an avian sarcoma virus oncogene (src) and proposed amino acid sequence for gene product | Q28263712 | ||
| The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane | Q28575831 | ||
| Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis | Q29547747 | ||
| Transforming gene product of Rous sarcoma virus phosphorylates tyrosine | Q29620005 | ||
| Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinase | Q33986868 | ||
| Characterization of the protein kinase activity of avian sarcoma virus src gene product | Q34036059 | ||
| Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus | Q35058806 | ||
| Intracellular protein topogenesis | Q36360251 | ||
| Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product | Q36394145 | ||
| Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus | Q36398185 | ||
| Identification of proteolytically resistant domains of human erythrocyte spectrin | Q36408832 | ||
| Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylation | Q36493768 | ||
| Preparation of syngeneic tumor regressor serum reactive with the unique determinants of the Abelson murine leukemia virus-encoded P120 protein at the cell surface | Q36502242 | ||
| Protein kinase activity associated with the avian sarcoma virus src gene product | Q37584831 | ||
| The Assembly of Proteins into Biological Membranes: The Membrane Trigger Hypothesis | Q38000320 | ||
| Membrane Asymmetry | Q39859559 | ||
| The molecular organization of membranes | Q39888451 | ||
| Virus-specific messenger RNAs in permissive cells infected by avian sarcoma virus | Q40245741 | ||
| Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry | Q40273384 | ||
| Surface modulation in cell recognition and cell growth | Q40490719 | ||
| Evidence that the src gene product of rous sarcoma virus is membrane associated | Q44731356 | ||
| The structure and protein kinase activity of proteins encoded by nonconditional mutants and back mutants in thesrc gene of avian sarcoma virus | Q45801663 | ||
| The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine | Q45802887 | ||
| Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus | Q45803202 | ||
| Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine | Q45803653 | ||
| Localization of the src gene product of the Harvey strain of MSV to plasma membrane of transformed cells by electron microscopic immunocytochemistry | Q53577737 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | viral protein | Q952587 |
| Rous sarcoma virus | Q1444330 | ||
| P304 | page(s) | 1624-1628 | |
| P577 | publication date | 1981-03-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src) | |
| P478 | volume | 78 |
| Q47234418 | 42,000-molecular weight EGF receptor has protein kinase activity |
| Q24616538 | A noncatalytic domain conserved among cytoplasmic protein-tyrosine kinases modifies the kinase function and transforming activity of Fujinami sarcoma virus P130gag-fps |
| Q36947661 | A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformation |
| Q40128092 | A single point mutation has pleiotropic effects on pp60v-src function |
| Q42821137 | A truncated v-abl-derived tyrosine-specific tyrosine kinase expressed in Escherichia coli |
| Q40135006 | Abelson Leukemia Virus |
| Q36710757 | Activation of the proto-oncogene p60c-src by point mutations in the SH2 domain |
| Q35610574 | Activation of the transforming potential of p60c-src by a single amino acid change |
| Q36895337 | Adenovirus cyt+ locus, which controls cell transformation and tumorigenicity, is an allele of lp+ locus, which codes for a 19-kilodalton tumor antigen. |
| Q30449986 | Amino Acid Alterations Within a Highly Conserved Region of the Rous Sarcoma Virus src Gene Product pp60src Inactivate Tyrosine Protein Kinase Activity |
| Q40667798 | Amino acid substitutions sufficient to convert the nontransforming p60c-src protein to a transforming protein |
| Q45796833 | Analysis of the catalytic domain of phosphotransferase activity of two avian sarcoma virus-transforming proteins |
| Q72711588 | Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60src |
| Q24558728 | Association of the v-crk oncogene product with phosphotyrosine-containing proteins and protein kinase activity |
| Q45800368 | Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus |
| Q72657751 | Bacterial expression of an enzymatically active protein encoded by RSV src gene |
| Q36948284 | Cell surface expression of v-fms-coded glycoproteins is required for transformation |
| Q41570236 | Cellular distribution of p68, a new calcium-binding protein from lymphocytes |
| Q45077792 | Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicity |
| Q67663346 | Characterization of purified pp60c-src protein tyrosine kinase from human platelets |
| Q44407439 | Characterization of structural domains of the human epidermal growth factor receptor obtained by partial proteolysis |
| Q40136609 | Construction and biological analysis of deletion mutants of Fujinami sarcoma virus: 5'-fps sequence has a role in the transforming activity |
| Q45798296 | Correlation between tumor-specific surface antigens and src gene expression in Rous sarcoma virus-induced rat tumors |
| Q36888913 | Creation of a chimeric oncogene: analysis of the biochemical and biological properties of v-erbB/src fusion polypeptide |
| Q45797944 | Cyclic AMP treatment of Rous sarcoma virus-transformed Chinese hamster ovary cells increases phosphorylation of pp60src and increases pp60src kinase activity |
| Q36924844 | DNA sequence of the viral and cellular src gene of chickens. 1. Complete nucleotide sequence of an EcoRI fragment of recovered avian sarcoma virus which codes for gp37 and pp60src. |
| Q40135025 | Defective Avian Sarcoma Viruses |
| Q30452209 | Deletions and insertions within an amino-terminal domain of pp60v-src inactivate transformation and modulate membrane stability |
| Q36767710 | Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein |
| Q36901811 | Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src |
| Q28365927 | Detection of phosphotyrosine-containing proteins in the detergent-insoluble fraction of RSV-transformed fibroblasts by azobenzene phosphonate antibodies |
| Q36902959 | Development and characterization of antisera specific for amino- and carboxy-terminal regions of pp60src |
| Q36209147 | Discrete primary locations of a tyrosine-protein kinase and of three proteins that contain phosphotyrosine in virally transformed chick fibroblasts |
| Q39960487 | Dual acylation and lipid raft association of Src-family protein tyrosine kinases are required for SDF-1/CXCL12-mediated chemotaxis in the Jurkat human T cell lymphoma cell line |
| Q30195430 | Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src |
| Q40037901 | Epidermal growth factor (EGF) modulation of feline sarcoma virus fms tyrosine kinase activity, internalization, degradation, and transforming potential in an EGF receptor/v-fms chimera |
| Q45799132 | Evidence that the Rous sarcoma virus transforming gene product is associated with glycerol kinase activity |
| Q36944690 | Expression of the src and abl cellular oncogenes during development of Drosophila melanogaster |
| Q37680271 | Fine structural mapping of a critical NH2-terminal region of p60src |
| Q48399723 | Frameshift and intragenic suppressor mutations in a rous sarcoma provirus suggest src encodes two proteins |
| Q36946370 | Functional Domains of the pp60v-src Protein as Revealed by Analysis of Temperature-Sensitive Rous Sarcoma Virus Mutants |
| Q36869296 | Genetic analysis of p60v-src domains involved in the induction of different cell transformation parameters |
| Q59085677 | Growth factors: The epidermal growth factor receptor gene and its product |
| Q70792288 | High tyrosine protein kinase activities in soluble and particulate fractions in bone marrow cells |
| Q34469297 | Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src |
| Q42826369 | Identification of platelet membrane proteins that interact with amino-terminal peptides of pp60c-src |
| Q30452226 | Inhibition of the tyrosine kinase activity of v-src, v-fgr, and v-yes gene products by a monoclonal antibody which binds both amino and carboxy peptide fragments of pp60v-src. |
| Q36935658 | Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This Complex |
| Q36920345 | Interactions between polyomavirus medium T antigen and three cellular proteins of 88, 61, and 37 kilodaltons |
| Q40126755 | Intracellular localization and processing of pp60v-src proteins expressed by two distinct temperature-sensitive mutants of Rous sarcoma virus |
| Q36422848 | Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus |
| Q30009924 | Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism |
| Q36905106 | Mapping of multiple phosphorylation sites within the structural and catalytic domains of the Fujinami avian sarcoma virus transforming protein |
| Q39578212 | Modification of proteins with covalent lipids |
| Q36917801 | Molecular cloning and characterization of avian sarcoma virus UR2 and comparison of its transforming sequence with those of other avian sarcoma viruses |
| Q34343460 | Molecular genetic characterization of the mRNA coding for an inducible suppressor factor specific for L-glutamic acid60-L-alanine30-L-tyrosine10. |
| Q36916263 | Monoclonal antibodies to the transforming protein of Fujinami avian sarcoma virus discriminate between different fps-encoded proteins |
| Q36888783 | Morphf mutants of Rous sarcoma virus: nucleotide sequencing analysis suggests that a class of morphf mutants was generated through splicing of a cryptic intron. |
| Q40101797 | Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen |
| Q36460089 | Myristylation site in Pr65gag is essential for virus particle formation by Moloney murine leukemia virus |
| Q36916467 | N-terminal deletion in the src gene of Rous sarcoma virus results in synthesis of a 45,000-Mr protein with mitogenic activity. |
| Q36895142 | N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src gene |
| Q36910596 | Neither arginine nor histidine can carry out the function of lysine-295 in the ATP-binding site of p60src |
| Q45800232 | Novel localization of pp60src in rous sarcoma virus-transformed rat and goat cells and in chicken cells transformed by viruses rescued from these mammalian cells |
| Q36244780 | Nucleotide sequence of the feline retroviral oncogene v-fms shows unexpected homology with oncogenes encoding tyrosine-specific protein kinases |
| Q38746581 | Oncogenes, protooncogenes, and signal transduction: toward a unified theory? |
| Q67269766 | Only membrane-associated RSV src proteins have amino-terminally bound lipid |
| Q41660724 | Partial purification and characterization of the lck protein-tyrosine kinase from bovine thymus |
| Q40135379 | Pericellular matrix in malignant transformation. |
| Q36306117 | Phospholipids stimulate phosphorylation of vinculin by the tyrosine-specific protein kinase of Rous sarcoma virus |
| Q36304288 | Platelet-derived growth factor stimulates tyrosine-specific protein kinase activity in Swiss mouse 3T3 cell membranes |
| Q34612848 | Platelet-derived growth factor. Structure, function, and roles in normal and transformed cells |
| Q36895114 | Processing of p60v-src to its myristylated membrane-bound form |
| Q45800309 | Properties of the src kinase purified from Rous sarcoma virus-induced rat tumors |
| Q45946956 | Purification and enzymatic characterization of pp60c-src from human platelets |
| Q36941260 | Purification of a native membrane-associated adenovirus tumor antigen |
| Q41838604 | Rapid plasma membrane anchoring of newly synthesized p59fyn: selective requirement for NH2-terminal myristoylation and palmitoylation at cysteine-3. |
| Q40649687 | Reconstitution of the Rous sarcoma virus transforming protein pp60v-src into phospholipid vesicles |
| Q36978573 | Reduced Synthesis of pp60src and Expression of the Transformation-Related Phenotype in Interferon-Treated Rous Sarcoma Virus-Transformed Rat Cells |
| Q40254499 | Retroviruses and cancer genes. |
| Q36916539 | Rous sarcoma virus mutant dlPA105 induces different transformed phenotypes in quail embryonic fibroblasts and neuroretina cells |
| Q30193738 | SH3 domains specifically regulate kinase activity of expressed Src family proteins |
| Q30195875 | Site-directed mutagenesis of the SH2- and SH3-coding domains of c-src produces varied phenotypes, including oncogenic activation of p60c-src |
| Q30452305 | Site-directed mutagenesis of the src gene of Rous sarcoma virus: construction and characterization of a deletion mutant temperature sensitive for transformation. |
| Q30452297 | Site-directed point mutation in the src gene oF rous sarcoma virus results in an inactive src gene product |
| Q40674552 | Size-Variant pp60src Proteins of Recovered Avian Sarcoma Viruses Interact with Adhesion Plaques as Peripheral Membrane Proteins: Effects on Cell Transformation |
| Q40144115 | Small deletion in src of Rous sarcoma virus modifying transformation phenotypes: identification of 207-nucleotide deletion and its smaller product with protein kinase activity |
| Q30412370 | Specific proteolytic fragmentation of p60v-src in transformed cell lysates |
| Q36757700 | Structural differences between repressed and derepressed forms of p60c-src |
| Q36945448 | Structurally and functionally modified forms of pp60v-src in Rous sarcoma virus-transformed cell lysates |
| Q34254297 | Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus |
| Q45796304 | Subcellular localization of the v-erb-B protein, the product of a transforming gene of avian erythroblastosis virus |
| Q36936974 | Subcellular location of an abundant substrate (p36) for tyrosine-specific protein kinases |
| Q27483437 | Targeting of Moloney murine leukemia virus gag precursor to the site of virus budding |
| Q72696695 | Temperature-sensitive membrane association of pp60src in tsNY68-infected cells correlates with increased tyrosine phosphorylation of membrane-associated proteins |
| Q40137529 | The Pathogenesis of Oncogenic Avian Retrovirusesxs |
| Q45796450 | The avian sarcoma virus PRCII lacks 1020 nucleotides of the fps transforming gene |
| Q36761454 | The common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function |
| Q33939386 | The complex of polyoma virus middle-T antigen and pp60c-src |
| Q52861971 | The discovery of modular binding domains: building blocks of cell signalling. |
| Q36888063 | The membrane-binding domain and myristylation of p60v-src are not essential for stimulation of cell proliferation |
| Q36900351 | The minimum transforming region of v-abl is the segment encoding protein-tyrosine kinase |
| Q37378589 | The noncatalytic src homology region 2 segment of abl tyrosine kinase binds to tyrosine-phosphorylated cellular proteins with high affinity |
| Q34555150 | The src protein contains multiple domains for specific attachment to membranes |
| Q41427839 | The structure of the human c-fes/fps proto-oncogene |
| Q45798971 | The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid |
| Q59074352 | Three loci related to the src oncogene and tyrosine-specific protein kinase activity in Drosophila |
| Q36322218 | Transit of pp60v-src to the plasma membrane |
| Q36137603 | Two divergent cellular src genes are expressed in Xenopus laevis |
| Q36854215 | Two independent mutations are required for temperature-sensitive cell transformation by a Rous sarcoma virus temperature-sensitive mutant |
| Q36293710 | Viral src gene products are related to the catalytic chain of mammalian cAMP-dependent protein kinase |
| Q36915794 | pp60c-src has less affinity for the detergent-insoluble cellular matrix than do pp60v-src and other viral protein-tyrosine kinases. |
| Q36783080 | v-src mutations outside the carboxyl-coding region are not sufficient to fully activate transformation by pp60c-src in NIH 3T3 cells |
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