Intracellular localization and processing of pp60v-src proteins expressed by two distinct temperature-sensitive mutants of Rous sarcoma virus

scientific article published on June 1986

Intracellular localization and processing of pp60v-src proteins expressed by two distinct temperature-sensitive mutants of Rous sarcoma virus is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.58.3.876-883.1986
P932PMC publication ID252995
P698PubMed publication ID3009893

P2093author name stringWyke JA
Kellie S
Stoker AW
P2860cites workAvian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosineQ45803653
Three glycolytic enzymes are phosphorylated at tyrosine in cells transformed by Rous sarcoma virusQ45804878
Transformation by Rous sarcoma virus: A cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosineQ45805762
Identification and characterization of cellular targets for tyrosine protein kinases.Q53561041
Only membrane-associated RSV src proteins have amino-terminally bound lipidQ67269766
Temperature-sensitive membrane association of pp60src in tsNY68-infected cells correlates with increased tyrosine phosphorylation of membrane-associated proteinsQ72696695
Antibodies against synthetic peptides as a tool for functional analysis of the transforming protein pp60srcQ72711588
Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoproteinQ24297885
Nucleotide sequence of Abelson murine leukemia virus genome: structural similarity of its transforming gene product to other onc gene products with tyrosine-specific kinase activityQ24599865
Transforming gene product of Rous sarcoma virus phosphorylates tyrosineQ29620005
Rous sarcoma virus variants that encode src proteins with an altered carboxy terminus are defective for cellular transformationQ30452257
Identification of a polypeptide encoded by the avian sarcoma virus src geneQ33969897
Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinaseQ33986868
Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src)Q35326726
Evidence that the Rous sarcoma virus transforming gene product phosphorylates phosphatidylinositol and diacylglycerolQ36266572
Transit of pp60v-src to the plasma membraneQ36322218
Altered distributions of the cytoskeletal proteins vinculin and alpha-actinin in cultured fibroblasts transformed by Rous sarcoma virusQ36415878
Processing of p60v-src to its myristylated membrane-bound formQ36895114
N-terminal deletions in Rous sarcoma virus p60src: effects on tyrosine kinase and biological activities and on recombination in tissue culture with the cellular src geneQ36895142
Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma virusesQ36909345
Interaction Between the Rous Sarcoma Virus Transforming Protein and Two Cellular Phosphoproteins: Analysis of the Turnover and Distribution of This ComplexQ36935658
Highly purified pp60src induces the actin transformation in microinjected cells and phosphorylates selected cytoskeletal proteins in vitro.Q36935886
Transformation by avian sarcoma viruses leads to phosphorylation of multiple cellular proteins on tyrosine residuesQ36940699
Functional Domains of the pp60v-src Protein as Revealed by Analysis of Temperature-Sensitive Rous Sarcoma Virus MutantsQ36946370
A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformationQ36947661
Changes in Protein Phosphorylation in Rous Sarcoma Virus-Transformed Chicken Embryo CellsQ36966948
Identification of phosphotyrosine-containing proteins in untransformed and Rous sarcoma virus-transformed chicken embryo fibroblastsQ36973363
Mutation of NH2-terminal glycine of p60src prevents both myristoylation and morphological transformationQ37523303
Protein kinase activity associated with the avian sarcoma virus src gene productQ37584831
Mechanism of the decrease in the major cell surface protein of chick embryo fibroblasts after transformationQ40089823
Phenotypes of Rous sarcoma virus-transformed fibroblasts: An argument for a multifunctionalSrc gene productQ40125296
Subcellular localization of pp60src in RSV-transformed cellsQ40140350
Development of anti-pp60src serum with antigen produced in Escherichia coli.Q40143440
A mutant of rous sarcoma virus with a thermolabile defect in the virus envelopeQ40163180
Characterization of the avian sarcoma virus protein p60srcQ40193671
Tyrosine Phosphorylation of a 50K Cellular Polypeptide Associated with the Rous Sarcoma Virus Transforming Protein pp60srcQ40679227
Capping of cholera toxin-ganglioside GM1 complexes on mouse lymphocytes is accompanied by co-capping of alpha-actininQ41421795
Temperature-sensitive avian sarcoma viruses: a physiological comparison of twenty mutantsQ44138268
Two cellular proteins that immunoprecipitate with the transforming protein of Rous sarcoma virusQ44676897
Changes in amino-terminal sequences of pp60src lead to decreased membrane association and decreased in vivo tumorigenicityQ45077792
The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipidQ45798971
Mapping of nonconditional and conditional mutants in the src gene of Prague strain Rous sarcoma virusQ45800652
The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteinsQ45801434
Vinculin: A cytoskeletal target of the transforming protein of rous sarcoma virusQ45802101
The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosineQ45802887
Identification of a cellular protein substrate phosphorylated by the avian sarcoma virus-transforming gene productQ45802905
Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virusQ45803202
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectRous sarcoma virusQ1444330
P304page(s)876-883
P577publication date1986-06-01
P1433published inJournal of VirologyQ1251128
P1476titleIntracellular localization and processing of pp60v-src proteins expressed by two distinct temperature-sensitive mutants of Rous sarcoma virus
P478volume58