Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen

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Myristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.64.10.5163-5166.1990
P932PMC publication ID248010
P698PubMed publication ID2168992

P2093author name stringKaech S
Ballmer-Hofer K
Wyss A
P2860cites workAmino terminal myristylation of the protein kinase p60src, a retroviral transforming proteinQ28306986
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresisQ29547747
Specific proteolytic fragmentation of p60v-src in transformed cell lysatesQ30412370
Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src geneQ30450407
Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformationQ30450902
Monoclonal antibodies to Rous sarcoma virus pp60src react with enzymatically active cellular pp60src of avian and mammalian originQ30452279
Nonmyristoylated p60v-src fails to phosphorylate proteins of 115-120 kDa in chicken embryo fibroblastsQ33567250
Phosphorylation of polyoma middle T antigen and cellular proteins in purified plasma membranes of polyoma virus-infected cells.Q33931724
Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmidsQ34252848
Structural and functional domains of the Rous sarcoma virus transforming protein (pp60src)Q35326726
Peptide antibodies to the human c-fyn gene product demonstrate pp59c-fyn is capable of complex formation with the middle-T antigen of polyomavirusQ35996377
Carboxy terminus of polyoma middle-sized tumor antigen is required for attachment to membranes, associated protein kinase activities, and cell transformationQ36298676
Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylationQ36493768
Polyomavirus transforms rat F111 and mouse NIH 3T3 cells by different mechanismsQ36780724
Investigation of factors that influence phosphorylation of pp60c-src on tyrosine 527Q36790371
The absence of myristic acid decreases membrane binding of p60src but does not affect tyrosine protein kinase activityQ36862547
In vitro mutagenesis of the putative membrane-binding domain of polyomavirus middle-T antigenQ36864215
Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma virusesQ36909345
Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivoQ36915374
pp60c-src has less affinity for the detergent-insoluble cellular matrix than do pp60v-src and other viral protein-tyrosine kinases.Q36915794
Mutation causing premature termination of the polyoma virus medium T antigen blocks cell transformationQ36939555
Construction and Expression of a Recombinant DNA Gene Encoding a Polyomavirus Middle-Size Tumor Antigen with the Carboxyl Terminus of the Vesicular Stomatitis Virus Glycoprotein GQ36941236
A short sequence in the p60src N terminus is required for p60src myristylation and membrane association and for cell transformationQ36947661
Overexpression of the c-src protein does not induce transformation of NIH 3T3 cellsQ37577123
Fine structural mapping of a critical NH2-terminal region of p60srcQ37680271
Mechanisms of transformation by polyoma virus middle T antigenQ38198459
Identification and characterization of p59fyn (a src-like protein tyrosine kinase) in normal and polyoma virus transformed cellsQ41094990
Cytoplasmic interaction between pp60c-src and a truncated polyoma virus middle T antigenQ41260921
Subcellular localisation of the middle and large T-antigens of polyoma virusQ42269767
The polyoma virus oncogenes. Coordinated functions of three distinct proteins in the transformation of rodent cells in cultureQ44720821
Transmission of the polyoma virus middle T gene as the oncogene of a murine retrovirusQ45796659
Polyoma virus transforming protein associates with the product of the c-src cellular geneQ45798405
Transformation of rat cells by an altered polyoma virus genome expressing only the middle-T proteinQ45801875
Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformationQ45807428
Phosphorylation sites in enolase and lactate dehydrogenase utilized by tyrosine protein kinases in vivo and in vitro.Q53552017
Expression of influenza hemagglutinin-polyoma T-antigen fusion proteins in a rat embryo fibroblast cell line.Q54417120
Association of the polyomavirus middle-T antigen with c-yes proteinQ59098242
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)5163-5166
P577publication date1990-10-01
P1433published inJournal of VirologyQ1251128
P1476titleMyristylation of pp60c-src is not required for complex formation with polyomavirus middle-T antigen
P478volume64