Toxicological evaluation of a novel umami flavour compound: 2-(((3-(2,3-Dimethoxyphenyl)-1H-1,2,4-triazol-5-yl)thio)methyl)pyridine

scientific article published on 18 May 2016

Toxicological evaluation of a novel umami flavour compound: 2-(((3-(2,3-Dimethoxyphenyl)-1H-1,2,4-triazol-5-yl)thio)methyl)pyridine is …
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scholarly articleQ13442814

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P356DOI10.1016/J.TOXREP.2016.05.002
P932PMC publication ID5615911
P698PubMed publication ID28959573

P2093author name stringDonald S Karanewsky
Stacy Markison
Hanghui Liu
Amy J Arthur
Bert Chi
Lily Ida
P2860cites workHuman receptors for sweet and umami tasteQ22337199
Review of the regulation and safety assessment of food substances in various countries and jurisdictionsQ30393391
T1R receptors mediate mammalian sweet and umami tasteQ34995792
Sex-specific cytochrome P450 as a cause of sex- and species-related differences in drug toxicityQ35623893
Molecular mechanism for the umami taste synergismQ37023120
Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredientsQ37337553
Liver hypertrophy: a review of adaptive (adverse and non-adverse) changes--conclusions from the 3rd International ESTP Expert WorkshopQ38020789
Evaluation of cytochrome P450 inhibition assays using human liver microsomes by a cassette analysis /LC-MS/MS.Q42966023
Automated tight seal electrophysiology for assessing the potential hERG liability of pharmaceutical compoundsQ45238950
Sex-dependent metabolism of xenobiotics.Q50869900
In vitro assessment of cytochrome P450 inhibition: strategies for increasing LC/MS-based assay throughput using a one-point IC(50) method and multiplexing high-performance liquid chromatography.Q51913383
Physiological parameters in laboratory animals and humansQ72935917
Fluorometric high-throughput screening for inhibitors of cytochrome P450Q73201946
Microtiter plate assays for inhibition of human, drug-metabolizing cytochromes P450Q73402015
P304page(s)501-512
P577publication date2016-05-18
P1433published inToxicology reportsQ27725492
P1476titleToxicological evaluation of a novel umami flavour compound: 2-(((3-(2,3-Dimethoxyphenyl)-1H-1,2,4-triazol-5-yl)thio)methyl)pyridine
P478volume3

Reverse relations

Q41679211Toxicological evaluation and metabolism of two N-alkyl benzamide umami flavour compounds: N-(heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide and (R)-N-(1-methoxy-4-methylpentan-2-yl)-3,4-dimethylbenzamidecites workP2860

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