Lysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma

scientific article published on 6 June 2015

Lysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S10620-015-3734-5
P698PubMed publication ID26048020

P2093author name stringLei Zhao
Shan Huang
Zhigang Chen
Guobin Wu
Jiye Zhu
Chaoyuan Huang
Yinnong Zhao
Xianjian Li
P2860cites workGlobal cancer statisticsQ22241238
The Hallmarks of CancerQ221226
Management of hepatocellular carcinoma: An updateQ27860530
Lysyl oxidase: properties, specificity, and biological roles inside and outside of the cellQ28208372
Lysyl oxidase: a lung adenocarcinoma biomarker of invasion and survivalQ28236372
RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasisQ28236828
Lysyl oxidase plays a critical role in endothelial cell stimulation to drive tumor angiogenesisQ28280138
The role of lysyl oxidase in SRC-dependent proliferation and metastasis of colorectal cancerQ28304399
Tumor metastasis: mechanistic insights and clinical challengesQ29617676
Lysyl oxidase expression and inhibition in uveal melanomaQ33533735
Retinoic acid is a cofactor for translational regulation of vascular endothelial growth factor in human endometrial stromal cellsQ33576463
Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-1.Q33625023
Lysyl oxidase-related protein-1 promotes tumor fibrosis and tumor progression in vivoQ34187677
Lysyl oxidase: from basic science to future cancer treatmentQ34263983
Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cellsQ34887552
Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasisQ37235503
Vascular endothelial growth factor in the management of hepatocellular carcinoma: a review of literatureQ37564297
Molecular pathogenesis of hepatocellular carcinoma: altering transforming growth factor-β signaling in hepatocarcinogenesisQ37914625
Transforming growth factor-β as a therapeutic target in hepatocellular carcinomaQ38196739
Angiogenesis in cancer - general pathways and their therapeutic implicationsQ38198596
Differential regulation of TGF-β-induced, ALK-5-mediated VEGF release by SMAD2/3 versus SMAD1/5/8 signaling in glioblastomaQ38962204
Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.Q38973071
Intracellular lysyl oxidase: effect of a specific inhibitor on nuclear mass in proliferating cellsQ42163130
TGF-β1 induces endothelial cell apoptosis by shifting VEGF activation of p38(MAPK) from the prosurvival p38β to proapoptotic p38α.Q42175314
Expression of lysyl oxidase in human osteosarcoma and its clinical significance: a tumor suppressive role of LOX in human osteosarcoma cellsQ43804532
Increasing matrix stiffness upregulates vascular endothelial growth factor expression in hepatocellular carcinoma cells mediated by integrin β1.Q44711049
Matrix GLA protein stimulates VEGF expression through increased transforming growth factor-beta1 activity in endothelial cellsQ46172310
Members of the lysyl oxidase family are expressed during the development of the frog Xenopus laevisQ46826619
Lysyl oxidase regulates breast cancer cell migration and adhesion through a hydrogen peroxide-mediated mechanismQ46853176
Expression of the lysyl oxidase propeptide in hepatocellular carcinoma and its clinical relevanceQ47907123
Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling.Q54596208
Lysyl Oxidase Activates the Transcription Activity of Human Collagene III PromoterQ58620548
Primary carcinoma of the liver: a study of 100 cases among 48,900 necropsiesQ73490475
Quantitative analysis of vascular endothelial growth factor, microvascular density and their clinicopathologic features in human hepatocellular carcinomaQ81771446
The role of Twist1 in hepatocellular carcinoma angiogenesis: a clinical studyQ83134326
[Mechanism of lysyl oxidase (LOX) in breast cancer invasion and metastasis]Q84773371
P433issue10
P921main subjectendotheliumQ111140
P304page(s)3019-3031
P577publication date2015-06-06
P1433published inDigestive Diseases and SciencesQ15716711
P1476titleLysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma
P478volume60

Reverse relations

cites work (P2860)
Q38813691Advanced glycation end products upregulate lysyl oxidase and endothelin-1 in human aortic endothelial cells via parallel activation of ERK1/2-NF-κB and JNK-AP-1 signaling pathways
Q58764034Inhibition of lysyl oxidase expression by dextran sulfate affects invasion and migration of gastric cancer cells
Q90625330Lysyl oxidase impacts disease outcomes and correlates with global DNA hypomethylation in esophageal cancer
Q92666152Lysyl oxidase induces epithelial-mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma
Q28068373The role of integrins in TGFβ activation in the tumour stroma
Q92714751Under-expression of LKB1 is associated with enhanced p38-MAPK signaling in human hepatocellular carcinoma

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