Lysyl oxidase induces epithelial-mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma

scientific article published on 18 April 2019

Lysyl oxidase induces epithelial-mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/CAS.14010
P932PMC publication ID6550133
P698PubMed publication ID30919528

P50authorHideo BabaQ88403580
Shigeki NakagawaQ88464273
P2093author name stringKatsunori Imai
Hirohisa Okabe
Hiromitsu Hayashi
Yukiharu Hiyoshi
Tatsunori Miyata
Akira Chikamoto
Hidetoshi Nitta
Kota Arima
Yo-Ichi Yamashita
Yuki Kitano
Naoki Umezaki
P2860cites workHypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic nicheQ24606366
Targeting ECM Disrupts Cancer ProgressionQ26779300
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
Sorafenib in advanced hepatocellular carcinomaQ27861075
RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasisQ28236828
Adjuvant interferon therapy after curative therapy for hepatocellular carcinoma (HCC): a meta-regression approachQ33556245
Novel insights in the genetics of HCC recurrence and advances in transcriptomic data integrationQ33969329
Gene expression in fixed tissues and outcome in hepatocellular carcinoma.Q34235518
CaMKII Inhibitor KN-62 Blunts Tumor Response to Hypoxia by Inhibiting HIF-1α in Hepatoma CellsQ34382055
A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deteriorationQ35107005
Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinomaQ35619104
Forkhead Box F1 promotes breast cancer cell migration by upregulating lysyl oxidase and suppressing Smad2/3 signalingQ35933347
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy.Q36000813
Molecular mechanisms mediating metastasis of hypoxic breast cancer cellsQ36254122
Lysyl oxidase is associated with increased thrombosis and platelet reactivity.Q36700494
Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosisQ36788468
LOX expression in primary nasopharyngeal carcinoma: correlation with prognostic parameters and outcomeQ36946751
The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase.Q37126990
Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson's DiseaseQ37545889
Role of acyclic retinoid in the chemoprevention of hepatocellular carcinoma: basic aspects, clinical applications, and future prospectsQ38032886
Prevention of hepatitis C virus infection and liver cancer.Q38134547
Lysyl Oxidase, a Targetable Secreted Molecule Involved in Cancer MetastasisQ38687306
Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway InhibitionQ38726399
Lysyl Oxidase Is a Strong Determinant of Tumor Cell Colonization in BoneQ38741210
Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trialQ38785510
Lysyl oxidase is associated with the epithelial-mesenchymal transition of gastric cancer cells in hypoxiaQ38861074
Lysyl oxidase-like 2 is critical to tumor microenvironment and metastatic niche formation in hepatocellular carcinoma.Q38973071
Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cellsQ39043505
Suppression of tumor growth by designed dimeric epidithiodiketopiperazine targeting hypoxia-inducible transcription factor complex.Q39187272
Acyclic retinoid targets platelet-derived growth factor signaling in the prevention of hepatic fibrosis and hepatocellular carcinoma developmentQ39339193
Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblastsQ39396200
Unexpected high rate of early tumor recurrence in patients with HCV-related HCC undergoing interferon-free therapyQ39846654
Survival impact of lymphocyte infiltration into the tumor of hepatocellular carcinoma in hepatitis B virus-positive or non-B non-C patients who underwent curative resectionQ40127743
Persisting risk of hepatocellular carcinoma after hepatitis C virus cure monitored by a liver transcriptome signature.Q40252283
The long-term efficacy of combining nucleos(t)ide analog and low-dose hepatitis B immunoglobulin on post-transplant hepatitis B virus recurrence.Q40654117
Lysyl Oxidase Is Predictive of Unfavorable Outcomes and Essential for Regulation of Vascular Endothelial Growth Factor in Hepatocellular CarcinomaQ41690535
Triple positive tumor markers predict recurrence and survival in early stage hepatocellular carcinomaQ42254863
Prevention and risk factors of hepatitis B recurrence after living donor liver transplantationQ42263202
Cost effectiveness of direct-acting antiviral therapy for treatment-naive patients with chronic HCV genotype 1 infection in the veterans health administration.Q42992540
Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: subanalyses of a phase III trialQ44089673
Unexpected early tumor recurrence in patients with hepatitis C virus-related hepatocellular carcinoma undergoing interferon-free therapy: Issue of the interval between HCC treatment and antiviral therapyQ45332139
Brivanib in patients with advanced hepatocellular carcinoma who were intolerant to sorafenib or for whom sorafenib failed: results from the randomized phase III BRISK-PS study.Q45980006
Combination of Gene Expression Signature and Model for End-stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic HepatitisQ47439747
Enhancer of zeste homolog 2 (EZH2) promotes progression of cholangiocarcinoma cells by regulating cell cycle and apoptosisQ47931449
SEARCH: a phase III, randomized, double-blind, placebo-controlled trial of sorafenib plus erlotinib in patients with advanced hepatocellular carcinoma.Q50454368
Antitumour activity of an inhibitor of miR-34a in liver cancer with β-catenin-mutations.Q50997346
miR30a inhibits LOX expression and anaplastic thyroid cancer progression.Q51026708
Lysyl Oxidase (LOX) Transcriptionally Regulates SNAI2 Expression and TIMP4 Secretion in Human Cancers.Q53133741
P433issue6
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)2033-2043
P577publication date2019-04-18
P1433published inCancer ScienceQ326125
P1476titleLysyl oxidase induces epithelial-mesenchymal transition and predicts intrahepatic metastasis of hepatocellular carcinoma
P478volume110

Reverse relations

cites work (P2860)
Q92591575Identification of new hypoxia-regulated epithelial-mesenchymal transition marker genes labeled by H3K4 acetylation
Q98466194Intrinsic and Extrinsic Modulators of the Epithelial to Mesenchymal Transition: Driving the Fate of Tumor Microenvironment

Search more.