TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine.

scientific article published on 20 September 2017

TGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2017NatCo...8..620B
P356DOI10.1038/S41467-017-00658-6
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/s41467-017-00658-6
P932PMC publication ID5607002
P698PubMed publication ID28931816

P50authorBernard MalissenQ2898273
Marc DalodQ51852866
Toby LawrenceQ56433255
Sandrine HenriQ56441963
Björn E ClausenQ57022988
Calum C BainQ57340012
Charlotte ScottQ57340218
Liesbet MartensQ89035201
P2093author name stringJ N Samsom
A McI Mowat
J Montgomery
D Lindenbergh-Kortleve
Y Saeys
J M Kel
J Ober-Blöbaum
M J H Girard-Madoux
T F P Zangerle-Murray
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Smad2 and Smad3 Inversely Regulate TGF-β Autoinduction in Clostridium butyricum-Activated Dendritic Cells.Q41123906
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Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cellsQ42766901
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Intestinal CD103(-) dendritic cells migrate in lymph and prime effector T cells.Q43975582
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Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage.Q47762575
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CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis.Q50787445
IRF4 transcription-factor-dependent CD103(+)CD11b(+) dendritic cells drive mucosal T helper 17 cell differentiation.Q51002504
Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type.Q51852802
A new subset of CD103+CD8alpha+ dendritic cells in the small intestine expresses TLR3, TLR7, and TLR9 and induces Th1 response and CTL activity.Q53251529
TGF-beta is required to maintain the pool of immature Langerhans cells in the epidermis.Q54655839
Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM-1 expressionQ60430710
CD200 receptor and macrophage function in the intestineQ63409703
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune diseaseQ73542905
CD101 surface expression discriminates potency among murine FoxP3+ regulatory T cellsQ80819592
Conditional deletion of TGF-βR1 using Langerin-Cre mice results in Langerhans cell deficiency and reduced contact hypersensitivityQ85094762
Fate mapping of IL-17-producing T cells in inflammatory responsesQ24621244
Essential role for CD103 in the T cell-mediated regulation of experimental colitisQ24646106
Dendritic cell subsets in the intestinal lamina propria: ontogeny and functionQ26997819
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
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Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogensQ28509751
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A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanismQ29614266
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Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult miceQ34214131
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Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanismsQ34570917
CCR2(+)CD103(-) intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cellsQ34734057
Functional specializations of intestinal dendritic cell and macrophage subsets that control Th17 and regulatory T cell responses are dependent on the T cell/APC ratio, source of mouse strain, and regional localization.Q35091226
Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine.Q35577590
Interleukin 23 production by intestinal CD103(+)CD11b(+) dendritic cells in response to bacterial flagellin enhances mucosal innate immune defense.Q35784100
CD101 inhibits the expansion of colitogenic T cells.Q35905213
Autocrine/paracrine TGF-β1 inhibits Langerhans cell migrationQ36069078
Notch-RBP-J signaling controls the homeostasis of CD8- dendritic cells in the spleen.Q36229473
Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogenyQ36263627
Identification of Axl as a downstream effector of TGF-β1 during Langerhans cell differentiation and epidermal homeostasisQ36340889
A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cellsQ36377496
GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cellsQ36398839
Generation and transcriptional programming of intestinal dendritic cells: essential role of retinoic acidQ36421554
Classical dendritic cells are required for dietary antigen-mediated induction of peripheral T(reg) cells and toleranceQ36814061
IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responsesQ36882237
Colonic tolerance develops in the iliac lymph nodes and can be established independent of CD103(+) dendritic cellsQ36913735
The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2Q36949912
Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cellsQ37194931
Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalism.Q37194987
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)620
P577publication date2017-09-20
P1433published inNature CommunicationsQ573880
P1476titleTGFβR signalling controls CD103+CD11b+ dendritic cell development in the intestine
P478volume8

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cites work (P2860)
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