Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

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Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice is …
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scholarly articleQ13442814

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P356DOI10.1038/NI.2967
P932PMC publication ID4169290
P698PubMed publication ID25151491
P5875ResearchGate publication ID264986828

P50authorBernard MalissenQ2898273
David ArtisQ87929495
Frederic GeissmannQ42599216
Elisa Gomez PerdigueroQ48425563
Allan MowatQ50856396
Sandrine HenriQ56441963
Lisa C OsborneQ57286233
Calum C BainQ57340012
Charlotte ScottQ57340218
P2093author name stringAlberto Bravo-Blas
P2860cites workLamina propria macrophages in the human gastrointestinal mucosa: their distribution, immunohistological phenotype, and functionQ71175396
Mucosal IL-8 and TGF-beta recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cellsQ79774355
The monocyte-macrophage axis in the intestineQ26829853
Macrophages in intestinal homeostasis and inflammationQ26851960
Tissue-resident macrophagesQ26991488
Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout miceQ28585385
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasisQ29614347
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertionQ29618089
A lineage of myeloid cells independent of Myb and hematopoietic stem cellsQ29620147
Monocyte emigration from bone marrow during bacterial infection requires signals mediated by chemokine receptor CCR2Q29622852
Metagenomic analyses reveal antibiotic-induced temporal and spatial changes in intestinal microbiota with associated alterations in immune cell homeostasisQ30920058
The origin and development of nonlymphoid tissue CD103+ DCs.Q33590397
Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC networkQ33590503
Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in miceQ33742156
Haematopoietic stem cells derive directly from aortic endothelium during developmentQ33805589
The mononuclear phagocyte system: a new classification of macrophages, monocytes, and their precursor cellsQ34052310
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasisQ34646876
Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytesQ34650719
Intestinal lamina propria dendritic cell subsets have different origin and functions.Q35001346
Origins and functional specialization of macrophages and of conventional and monocyte-derived dendritic cells in mouse skinQ35030843
Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.Q35679555
Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophagesQ36021832
Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursorsQ36775202
Multicolor fate mapping of Langerhans cell homeostasisQ37125737
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF.Q37194936
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodesQ37286595
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammationQ37581780
Origin and functions of tissue macrophages.Q38230878
The stream of precursors that colonizes the thymus proceeds selectively through the early T lineage precursor stage of T cell developmentQ38271118
Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80Q42074128
Origin of the lamina propria dendritic cell networkQ42117974
Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditionsQ45058656
Kinetics of central nervous system microglial and macrophage engraftment: analysis using a transgenic bone marrow transplantation model.Q45882945
Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditionsQ46891042
Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes.Q50032899
Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool.Q50515193
Local self-renewal can sustain CNS microglia maintenance and function throughout adult life.Q50656963
CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis.Q50787445
A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation.Q53237419
Origin of dendritic cells in peripheral lymphoid organs of mice.Q53558035
An independent subset of TLR expressing CCR2-dependent macrophages promotes colonic inflammation.Q54427475
Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10Q58363356
CD200 receptor and macrophage function in the intestineQ63409703
Direct evidence of monocyte recruitment to inflammatory bowel disease mucosaQ70801967
P2507corrigendum / erratumErratum: Corrigendum: Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult miceQ60507265
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
P304page(s)929-937
P577publication date2014-08-24
P1433published inNature ImmunologyQ1071725
P1476titleConstant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice
P478volume15

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Q91807678The Role of Immune Cells and Cytokines in Intestinal Wound Healing
Q92188718The Role of Macrophages in HIV-1 Persistence and Pathogenesis
Q38951470The Role of the Microbiota in Shaping Infectious Immunity
Q64261973The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
Q58730196The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages
Q40526547The battlefield in the war against attaching-and-effacing bacterial pathogens: Monocytes, macrophages and dendritic cells in action
Q38964911The contributions of lung macrophage and monocyte heterogeneity to influenza pathogenesis
Q26774975The development and maintenance of resident macrophages
Q33886544The fate and lifespan of human monocyte subsets in steady state and systemic inflammation
Q91621959The influence of environment and origin on brain resident macrophages and implications for therapy
Q27016634The interaction of anticancer therapies with tumor-associated macrophages
Q89507027The metabolic axis of macrophage and immune cell polarization
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Q34492976The pancreas anatomy conditions the origin and properties of resident macrophages
Q38749477The pattern of GPI-80 expression is a useful marker for unusual myeloid maturation in peripheral blood
Q51733213The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche.
Q38673089The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis.
Q49310867The tumour microenvironment creates a niche for the self-renewal of tumour-promoting macrophages in colon adenoma.
Q38478216The unusual suspects--innate lymphoid cells as novel therapeutic targets in IBD.
Q97568520The use of fecal microbiota transplant in sepsis
Q38751084Three Unique Interstitial Macrophages in the Murine Lung at Steady State
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Q38260567Tissue macrophage identity and self-renewal.
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Q47663189Tissue-Resident Macrophages in Fungal Infections
Q51806878Tissue-Resident Macrophages in Pancreatic Ductal Adenocarcinoma Originate from Embryonic Hematopoiesis and Promote Tumor Progression.
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Q48425484Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors.
Q35201949Tissue-resident macrophages: then and now.
Q55000062Tissue-specific Role of CX3CR1 Expressing Immune Cells and Their Relationships with Human Disease.
Q40350712Tissue-specific differentiation of colonic macrophages requires TGFβ receptor-mediated signaling
Q26779410Transcriptional Regulation of Mononuclear Phagocyte Development
Q47256407Transcriptional and functional profiling defines human small intestinal macrophage subsets.
Q39221646Transcriptional control of monocyte and macrophage development
Q39604232Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation
Q36111469Triglyceride-Rich Lipoproteins Modulate the Distribution and Extravasation of Ly6C/Gr1(low) Monocytes
Q37346644Tumor macrophages are pivotal constructors of tumor collagenous matrix.
Q34044797Tumor-induced myeloid deviation: when myeloid-derived suppressor cells meet tumor-associated macrophages
Q58792673Understanding the Biology of Self-Renewing Macrophages
Q54217613Understanding the Cellular Origin of the Mononuclear Phagocyte System Sheds Light on the Myeloid Postulate of Immune Paralysis in Sepsis.
Q61449505Understanding the Functional Properties of Neonatal Dendritic Cells: A Doorway to Enhance Vaccine Effectiveness?
Q35674290Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms
Q92813564Understanding the Relevance of DNA Methylation Changes in Immune Differentiation and Disease
Q55967623Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal
Q101166763Water quality check: macrophages setting the standards
Q48126684Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines
Q90482861Yin-yang effect of tumour cells in breast cancer: from mechanism of crosstalk between tumour-associated macrophages and cancer-associated adipocytes
Q48293548Yolk sac macrophage progenitors traffic to the embryo during defined stages of development.
Q92011402Yolk-sac-derived macrophages progressively expand in the mouse kidney with age
Q36712469β7-Integrin exacerbates experimental DSS-induced colitis in mice by directing inflammatory monocytes into the colon

Q60507265Erratum: Corrigendum: Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult micemain subjectP921

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