Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily

scientific article published on January 1990

Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID2299601

P2093author name stringGonzalez FJ
Aoyama T
Relling MV
Meyer UA
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)442-447
P577publication date1990-01-01
P1433published inJournal of Pharmacology and Experimental TherapeuticsQ1500272
P1476titleTolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP2C subfamily
P478volume252

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cites work (P2860)
Q34358861A screening test for slow metabolisers of tolbutamide
Q34403343A study of the interaction of omeprazole and warfarin in anticoagulated patients
Q40925106Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone
Q35826971Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism
Q41478156Clinical pharmacokinetics of tretinoin
Q84695565Comparative cytotoxicity of non-steroidal anti-inflammatory drugs in primary cultures of rat hepatocytes
Q24317436Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A
Q44815207Cytochrome P450 2C9 phenotyping using low-dose tolbutamide
Q24683497Cytochrome P4502C9: an enzyme of major importance in human drug metabolism
Q71377766Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans
Q42284671Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes
Q41428950Drug interactions with proton pump inhibitors
Q36350528Effect of genetic polymorphisms in cytochrome p450 (CYP) 2C9 and CYP2C8 on the pharmacokinetics of oral antidiabetic drugs: clinical relevance
Q33789233Effects of liver disease on pharmacokinetics. An update
Q47651375Effects of subacutely administered saiboku-to, an oriental herbal medicine, on pharmacodynamics and pharmacokinetics of diazepam in rodents
Q33645193Five of 12 forms of vaccinia virus-expressed human hepatic cytochrome P450 metabolically activate aflatoxin B1
Q43790044Gender difference in ifosfamide metabolism by human liver microsomes
Q36054252Genetic polymorphism of cytochrome P450 2C9 in a Caucasian and a black African population.
Q34844146Human cytochromes P450: evolution and cDNA-directed expression
Q36330247Human liver microsomal metabolism of the enantiomers of warfarin and acenocoumarol: P450 isozyme diversity determines the differences in their pharmacokinetics
Q34347501Identification of human CYP isoforms involved in the metabolism of propranolol enantiomers—N‐desisopropylation is mediated mainly by CYP1A2
Q28344127In vitro inhibition of the cytochrome P450 (CYP450) system by the antiplatelet drug ticlopidine: potent effect on CYP2C19 and CYP2D6
Q44271677In vitro modulatory effects of flavonoids on human cytochrome P450 2C8 (CYP2C8).
Q24550617Inhibition of cytochrome P450 (CYP450) isoforms by isoniazid: potent inhibition of CYP2C19 and CYP3A
Q34983265Interactions between antiretroviral drugs and drugs used for the therapy of the metabolic complications encountered during HIV infection.
Q41073233Molecular basis of polymorphic drug metabolism
Q36890310Omeprazole drug interaction studies
Q35759089P450 enzymes. Inhibition mechanisms, genetic regulation and effects of liver disease
Q40730354Pharmacogenetic phenotyping and genotyping. Present status and future potential.
Q37424309Pharmacogenetics in diabetes
Q41128197Pharmacokinetics, metabolism and interactions of acid pump inhibitors. Focus on omeprazole, lansoprazole and pantoprazole
Q43204859Relationship between phenytoin and tolbutamide hydroxylations in human liver microsomes
Q42792678Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics
Q41578273Site-directed mutation studies of human liver cytochrome P-450 isoenzymes in the CYP2C subfamily
Q43201774Tenidap sodium does not alter the clearance or plasma protein binding of tolbutamide in healthy male volunteers
Q38110432The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs

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