Acetaminophen prevents hyperalgesia in central pain cascade

scientific article published on 27 June 2008

Acetaminophen prevents hyperalgesia in central pain cascade is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.NEULET.2008.06.062
P932PMC publication ID2669887
P698PubMed publication ID18601979
P5875ResearchGate publication ID5251278

P2093author name stringXiao-Ying Hua
Osamu Saito
Tony L Yaksh
Shelle Malkmus
Bethany Fitzsimmons
Brianna Crawley
P2860cites workThe acute antihyperalgesic action of nonsteroidal, anti-inflammatory drugs and release of spinal prostaglandin E2 is mediated by the inhibition of constitutive spinal cyclooxygenase-2 (COX-2) but not COX-1.Q43697187
Acetaminophen distribution in the rat central nervous systemQ43725227
Nonopioid actions of intrathecal dynorphin evoke spinal excitatory amino acid and prostaglandin E2 release mediated by cyclooxygenase-1 and -2.Q44762691
Characterization of variables defining hindpaw withdrawal latency evoked by radiant thermal stimuli.Q45931253
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibitionQ46223466
Chronic catheterization of the spinal subarachnoid spaceQ48344815
Intrathecal morphine inhibits substance P release from mammalian spinal cord in vivoQ59061346
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenaseQ24563699
Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous systemQ28182188
Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthaseQ28195096
The spinal phospholipase-cyclooxygenase-prostanoid cascade in nociceptive processingQ28216388
Mechanism of action of paracetamolQ28303483
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesiaQ29620385
Orally administered paracetamol does not act locally in the rat formalin test: evidence for a supraspinal, serotonin-dependent antinociceptive mechanismQ33972718
Cellular mechanisms of acetaminophen: role of cyclo-oxygenase.Q40459784
Intrathecal substance P-induced thermal hyperalgesia and spinal release of prostaglandin E2 and amino acidsQ41613425
Acetaminophen blocks spinal hyperalgesia induced by NMDA and substance PQ41663135
The effect of morphine on formalin-evoked behaviour and spinal release of excitatory amino acids and prostaglandin E2 using microdialysis in conscious ratsQ42369976
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectparacetamolQ57055
P1104number of pages4
P304page(s)50-53
P577publication date2008-06-27
P1433published inNeuroscience LettersQ7002625
P1476titleAcetaminophen prevents hyperalgesia in central pain cascade
P478volume442

Reverse relations

cites work (P2860)
Q38795561Clinical update on benefit versus risks of oral paracetamol alone or with codeine: still a good option?
Q45991016In vitro clearance of intravenous acetaminophen in extracorporeal membrane oxygenation.
Q27002820Neonatal pain
Q43148670Preventive effect of intrathecal paracetamol on spinal cord injury in rats
Q34347558The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

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