Activity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinib

scientific article published on 7 November 2012

Activity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinib is …
instance of (P31):
case reportQ2782326
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1013263520
P356DOI10.1186/1477-7819-10-235
P932PMC publication ID3542167
P698PubMed publication ID23134665
P5875ResearchGate publication ID233328396

P2093author name stringYing Yuan
Hong Shen
Shenglin Ma
Yinghong Hu
Chunwen Tan
Modan Li
Xuefeng Fang
P2860cites workClinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancersQ29615475
Activity of pemetrexed against brain metastases in a patient with adenocarcinoma of the lungQ33431633
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancerQ34557318
Response and resistance in a non-small-cell lung cancer patient with an epidermal growth factor receptor mutation and leptomeningeal metastases treated with high-dose gefitinibQ34566991
Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigmQ34632917
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancerQ37274280
High dose weekly erlotinib achieves therapeutic concentrations in CSF and is effective in leptomeningeal metastases from epidermal growth factor receptor mutant lung cancerQ37681047
Personalized Medicine in Non–Small-Cell Lung Cancer: Is KRAS a Useful Marker in Selecting Patients for Epidermal Growth Factor Receptor–Targeted Therapy?Q37797818
De novo resistance to epidermal growth factor receptor-tyrosine kinase inhibitors in EGFR mutation-positive patients with non-small cell lung cancerQ38417668
Pemetrexed and cisplatin with concurrent radiotherapy for locally advanced non-small cell and limited disease small cell lung cancer: results from 2 phase I studiesQ43185507
Epidermal growth factor receptor targeted therapy by ZD 1839 (Iressa) in patients with brain metastases from non-small cell lung cancer (NSCLC).Q44519250
Gefitinib as a first line of therapy in non-small cell lung cancer with brain metastasesQ45093737
Effect of gefitinib ('Iressa', ZD1839) on brain metastases in patients with advanced non-small-cell lung cancerQ45098702
Activity of Pemetrexed on brain metastases from Non-Small Cell Lung Cancer.Q45919728
Treatment of brain metastasis from non-small cell lung cancer with whole brain radiotherapy and Gefitinib in a Chinese populationQ46193107
Efficacy of platinum-based chemotherapy after cranial radiation in patients with brain metastasis from non-small cell lung cancerQ46535764
Gefitinib is also active for carcinomatous meningitis in NSCLC.Q46604361
Gefitinib as palliative therapy for lung adenocarcinoma metastatic to the brainQ48203077
Intracarotid low dose bradykinin infusion selectively increases tumor permeability through activation of bradykinin B2 receptors in malignant gliomasQ48443469
The prognostic factors of lung cancer patients with brain metastases treated with radiotherapyQ48496818
Pemetrexed and cisplatin as first-line chemotherapy for advanced non-small-cell lung cancer (NSCLC) with asymptomatic inoperable brain metastases: a multicenter phase II trial (GFPC 07-01)Q83411205
P304page(s)235
P577publication date2012-11-07
P1433published inWorld Journal of Surgical OncologyQ14520241
P1476titleActivity of pemetrexed and high-dose gefitinib in an EGFR-mutated lung adenocarcinoma with brain and leptomeningeal metastasis after response to gefitinib
P478volume10

Reverse relations

cites work (P2860)
Q46354602A case report of patient with advanced non-small cell lung cancer by five times EGFR-TKIs therapy
Q26781690Diagnosis and Treatment of Leptomeningeal Metastasis in Non-small Cell Lung Cancer
Q38971627Experimental Treatments for Leptomeningeal Metastases From Solid Malignancies
Q47133535Leptomeningeal Disease and the Evolving Role of Molecular Targeted Therapy and Immunotherapy
Q31121041Pemetrexed/cisplatin as first-line chemotherapy for advanced lung cancer with brain metastases: A case report and literature review
Q37368787Phase II clinical trial of whole-brain irradiation plus three-dimensional conformal boost with concurrent topotecan for brain metastases from lung cancer
Q37108253Quick regression of brain metastases from lung adenocarcinoma with epidermal growth factor receptor-tyrosine kinase inhibitor treatment: A case report and literature review
Q49894049Targeted therapy for leptomeningeal metastases in non-small cell lung cancer - Changing treatment paradigms
Q26740529The role of EGFR-TKI for leptomeningeal metastases from non-small cell lung cancer
Q55504755[Research progress of lung cancer with leptomeningeal metastasis].

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