From radioimmunoassay to mass spectrometry: a new method to quantify orexin-A (hypocretin-1) in cerebrospinal fluid.

scientific article published on 11 May 2016

From radioimmunoassay to mass spectrometry: a new method to quantify orexin-A (hypocretin-1) in cerebrospinal fluid. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/SREP25162
P932PMC publication ID4863245
P698PubMed publication ID27165941

P50authorYves DauvilliersQ30500684
Chrisophe HirtzQ67221786
Audrey GABELLEQ67221789
Jérôme VialaretQ88373339
P2093author name stringSylvain Lehmann
Nora Nowak
P2860cites workAmyloid-beta dynamics are regulated by orexin and the sleep-wake cycleQ24644961
Statistical methods for assessing agreement between two methods of clinical measurementQ26778461
Amyloid-β diurnal pattern: possible role of sleep in Alzheimer's disease pathogenesisQ27026835
Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexantQ27696899
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brainsQ28145391
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviorQ28266541
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulationQ29615680
Neurons containing hypocretin (orexin) project to multiple neuronal systemsQ29619641
Hypocretin and brain β-amyloid peptide interactions in cognitive disorders and narcolepsy.Q33737141
Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasmaQ33794491
The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders.Q33910875
Reduced number of hypocretin neurons in human narcolepsyQ33923479
The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomniasQ34153927
Hypocretin (orexin) loss in Alzheimer's diseaseQ34183012
Selected reaction monitoring-based proteomics: workflows, potential, pitfalls and future directionsQ34279143
Cerebrospinal fluid melanin-concentrating hormone (MCH) and hypocretin-1 (HCRT-1, orexin-A) in Alzheimer's diseaseQ34344331
Localized loss of hypocretin (orexin) cells in narcolepsy without cataplexyQ34611455
The role of hypocretins (orexins) in sleep regulation and narcolepsy.Q34674865
Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer's diseaseQ34708307
CSF hypocretin-1 levels in narcolepsy, Kleine-Levin syndrome, and other hypersomnias and neurological conditionsQ35560285
How amyloid, sleep and memory connectQ36629693
Narcolepsy with cataplexyQ36733271
Endogenous interference in immunoassays in clinical chemistry. A reviewQ37996345
Overview of orexin/hypocretin systemQ38027688
Quantitative Clinical Chemistry Proteomics (qCCP) using mass spectrometry: general characteristics and applicationQ38062812
Interactions of the histamine and hypocretin systems in CNS disorders.Q38534913
Cataplexy--clinical aspects, pathophysiology and management strategy.Q47867265
Orexinergic system dysregulation, sleep impairment, and cognitive decline in Alzheimer disease.Q48022782
CSF beta-amyloid levels are altered in narcolepsy: a link with the inflammatory hypothesis?Q48119299
Relationship between CSF hypocretin levels and hypocretin neuronal lossQ48602913
Advances in multiplexed MRM-based protein biomarker quantitation toward clinical utility.Q50873210
CLSI EP17-A protocol: a useful tool for better understanding the low end performance of total prostate-specific antigen assays.Q51050011
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system.Q51435079
Interference with clinical laboratory analysesQ72792144
False-positive immunoassay results: a multicenter survey of erroneous immunoassay results from assays of 74 analytes in 10 donors from 66 laboratories in seven countriesQ78448084
The dynamic range problem in the analysis of the plasma proteomeQ84260348
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcerebrospinal fluidQ54196
P304page(s)25162
P577publication date2016-05-11
P1433published inScientific ReportsQ2261792
P1476titleFrom radioimmunoassay to mass spectrometry: a new method to quantify orexin-A (hypocretin-1) in cerebrospinal fluid
P478volume6

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cites work (P2860)
Q61444179HPLC analysis of CSF hypocretin-1 in type 1 and 2 narcolepsy
Q47728004Hypocretin measurement: shelf age of radioimmunoassay kit, but not freezer time, influences assay variability
Q56627695Narcolepsy
Q92035817Narcolepsy - clinical spectrum, aetiopathophysiology, diagnosis and treatment
Q47780791Orexin and Alzheimer's Disease
Q47747609Temporal Changes in the Cerebrospinal Fluid Level of Hypocretin-1 and Histamine in Narcolepsy.

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