Animal Model of Gestational Diabetes Mellitus with Pathophysiological Resemblance to the Human Condition Induced by Multiple Factors (Nutritional, Pharmacological, and Stress) in Rats.

scientific article published on 9 June 2016

Animal Model of Gestational Diabetes Mellitus with Pathophysiological Resemblance to the Human Condition Induced by Multiple Factors (Nutritional, Pharmacological, and Stress) in Rats. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2016/9704607
P932PMC publication ID4917720
P698PubMed publication ID27379252

P50authorRajesh RamasamyQ39829499
Cini Mathew JohnQ41844567
Fazlin Mohd FauziQ60975859
Nur Intan Saidaah Mohamed YusofQ87823618
P2093author name stringAishah Adam
Siti Hajar Abdul Aziz
Massita Nordin
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High-saturated-fat diet induces gestational diabetes and placental vasculopathy in C57BL/6 miceQ43215049
In response to oxidative stress, the expression of inflammatory cytokines and antioxidant enzymes are impaired in placenta, but not adipose tissue, of women with gestational diabetesQ43260568
Circulating interleukin-6 in relation to adiposity, insulin action, and insulin secretionQ43668496
Adipose tissue IL-6 content correlates with resistance to insulin activation of glucose uptake both in vivo and in vitroQ43982432
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Is low-dose streptozotocin in rats an adequate model for gestational diabetes mellitus?Q44448646
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Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screeningQ46568043
Effect of chronic psychological stress on insulin release from rat isolated pancreatic islets.Q46915579
Amelioration in hepatic insulin sensitivity by reduced hepatic lipid accumulation at short-term after Roux-en-Y gastric bypass surgery in type 2 diabetic rats.Q50965190
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Nicotinamide supplementation protects gestational diabetic rats by reducing oxidative stress and enhancing immune responses.Q54321188
Enhanced CD4+CD25+ regulatory T cells with splenic proliferation and protection against oxidative stress by nicotinamide in gestational diabetes.Q54329384
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Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamideQ74371051
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[Intrauterine fetal death in pregnancies of women with preconceptional and gestational diabetes mellitus and of women without glucose tolerance disorders. Results of the perinatal registry of Lower Saxony, Germany]Q79502386
Cellular mechanisms for insulin resistance in normal pregnancy and gestational diabetesQ80538214
Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondriaQ82984554
Akt, a pleckstrin homology domain containing kinase, is activated primarily by phosphorylationQ24312168
PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesisQ24610431
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The mechanism of alloxan and streptozotocin action in B cells of the rat pancreasQ28217509
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Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathwaysQ28346530
Insulin increases the association of Akt-2 with Glut4-containing vesiclesQ28573673
Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cellsQ28586458
Insulin signallingQ28611467
Free radicals, metals and antioxidants in oxidative stress-induced cancerQ29547711
Tempol, an intracellular antioxidant, inhibits tissue factor expression, attenuates dendritic cell function, and is partially protective in a murine model of cerebral malaria.Q30457536
Determination of the estrous cycle phases of rats: some helpful considerations.Q31136292
Insulin secretion during and after pregnancy in patients with gestational diabetes mellitusQ31831174
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Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistanceQ33941406
Women born preterm or with inappropriate weight for gestational age are at risk of subsequent gestational diabetes and pre-eclampsiaQ34221902
Role of the adipocyte, free fatty acids, and ectopic fat in pathogenesis of type 2 diabetes mellitus: peroxisomal proliferator-activated receptor agonists provide a rational therapeutic approachQ34294997
The obesity epidemic: challenges, health initiatives, and implications for gastroenterologistsQ34551353
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Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipidQ35013075
The stress response and the regulation of inflammatory diseaseQ35446539
Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in miceQ35486021
Gestational diabetes mellitus: risks and management during and after pregnancy.Q35505266
Oxidative stress and oxidant signaling in obstructive sleep apnea and associated cardiovascular diseasesQ36015440
Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in miceQ36125408
Different diabetogenic response to moderate doses of streptozotocin in pregnant rats, and its long-term consequences in the offspringQ36782258
Embryonic oxidative stress as a mechanism of teratogenesis with special emphasis on diabetic embryopathyQ36840277
Influences of weight loss on long-term diabetes outcomesQ37072014
Gestational diabetes mellitus: screening and outcomes in southern italian pregnant womenQ37182817
High-fat diet did not change metabolic response to acute stress in ratsQ37413814
Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysisQ37493828
Disturbances in lipid metabolism in diabetic pregnancy – Are these the cause of the problem?Q37787474
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectpathophysiologyQ1135939
gestational diabetesQ126691
P304page(s)9704607
P577publication date2016-06-09
P1433published inBioMed Research InternationalQ17509958
P1476titleAnimal Model of Gestational Diabetes Mellitus with Pathophysiological Resemblance to the Human Condition Induced by Multiple Factors (Nutritional, Pharmacological, and Stress) in Rats
P478volume2016

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cites work (P2860)
Q90011751Comparative effects of glibenclamide, metformin and insulin on fetal pancreatic histology and maternal blood glucose in pregnant streptozotocin-induced diabetic rats
Q60915852Maternal Cognitive Impairment Associated with Gestational Diabetes Mellitus-A Review of Potential Contributing Mechanisms

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