Failure of the inhibition of rat gastric mucosal 5-lipoxygenase by novel acetohydroxamic acids to prevent ethanol-induced damage

scientific article published on September 1988

Failure of the inhibition of rat gastric mucosal 5-lipoxygenase by novel acetohydroxamic acids to prevent ethanol-induced damage is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1476-5381.1988.TB16559.X
P8608Fatcat IDrelease_ff7arf4rjffyrn522fcszx7cwe
P932PMC publication ID1854125
P698PubMed publication ID3146394
P5875ResearchGate publication ID20010684

P2093author name stringWhittle BJ
Boughton-Smith NK
P2860cites workHistologic and microcirculatory changes in alcohol-induced gastric lesions in the rat: effect of prostaglandin cytoprotectionQ72745517
Antioxidation theory of non-steroidal anti-inflammatory drugs based upon the inhibition of luminol-enhanced chemiluminescence from the myeloperoxidase reactionQ72962691
Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: effects on bronchial anaphylaxis in anaesthetized guinea-pigsQ28361518
The effect of anti-inflammatory drugs on eicosanoid formation in a chronic model of inflammatory bowel disease in the rat.Q35755471
Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: effects on acute inflammatory responsesQ35755550
Relationship between the prevention of rat gastric erosions and the inhibition of acid secretion by prostaglandinsQ39121843
The effects of a novel series of selective inhibitors of arachidonate 5-lipoxygenase on anaphylactic and inflammatory responsesQ39221903
Early vascular injury and increased vascular permeability in gastric mucosal injury caused by ethanol in the rat.Q41484035
Selective inhibition of arachidonate 5-lipoxygenase by novel acetohydroxamic acids: biochemical assessment in vitro and ex vivoQ42543352
Inhibition of arachidonic acid cyclo-oxygenase and lipoxygenase activities of leukocytes by indomethacin and compound BW755C.Q42543571
Gastric vasoconstrictor actions of leukotriene C4, PGF2 alpha, and thromboxane mimetic U-46619 on rat submucosal microcirculation in vivoQ43725806
A radioimmunoassay for 6-keto-prostaglandin F1alphaQ44339122
Role of prostanoids in the protective actions of BW755C on the gastric mucosaQ44560235
On the formation of thromboxane B2 and 12l-hydroxy-5,8,10,14-eicosatetraenoic acid (12 ho-20:4) in tissues from the guinea pig.Q46353837
Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosaQ59096214
A radioimmunoassay for leukotriene B4Q67239475
Acetohydroxamic acids as potent, selective, orally active 5-lipoxygenase inhibitorsQ68277027
Ethanol stimulates formation of leukotriene C4 in rat gastric mucosaQ68868178
The effects of non-steroid anti-inflammatory drugs on leukocyte migration in carrageenin-induced inflammationQ71297693
Oxidation of phenidone and BW755C by prostaglandin endoperoxide synthetaseQ71606297
Release of leukotriene C4 from human polymorphonuclear leucocytes as determined by radioimmunoassayQ71628611
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)155-162
P577publication date1988-09-01
P1433published inBritish Journal of PharmacologyQ919631
P1476titleFailure of the inhibition of rat gastric mucosal 5-lipoxygenase by novel acetohydroxamic acids to prevent ethanol-induced damage
P478volume95

Reverse relations

cites work (P2860)
Q356440985-lipoxygenase inhibitors and their anti-inflammatory activities
Q67864223Aspirin-like drugs, ethanol-induced rat gastric injury and mueosal eicosanoid release
Q34377774Chronic nicotine intake causes vascular dysregulation in the rat gastric mucosa
Q43212724Colorectal leukotriene B4 synthesis in vitro in inflammatory bowel disease: inhibition by the selective 5-lipoxygenase inhibitor BWA4C
Q77794011Effect of dietary linoleate/alpha-linolenate balance on experimentally induced gastric injury in rats
Q42104671Effect of ethanol on eicosanoid synthesis by human gastric and colonic mucosal pieces
Q72344938Effects of chronic normovolemic anemia on gastric microcirculation and ethanol-induced gastric damage in rats
Q71726621Eicosanoid and gastroprotection by copper derivatives and NDGA
Q34376929Enhanced gastric mucosal leukotriene B4 synthesis in patients taking non-steroidal anti-inflammatory drugs
Q77800127Inhibition by leukotriene inhibitors, and calcium and platelet-activating factor antagonists, of acute gastric and intestinal damage in arthritic rats and in cholinomimetic-treated mice
Q71645081Inhibitory effect of DS-4574, a peptidoleukotriene antagonist with mast cell stabilizing action, on compound 48/80-induced gastric mucosal lesions in rats
Q36882130Leukotriene antagonists and inhibitors of leukotriene biosynthesis as potential therapeutic agents
Q44540547Leukotriene receptor blockade reduces bile acid-induced superficial gastric mucosal injury
Q43895002Protective effect of silymarin in antigen challenge- and histamine-induced bronchoconstriction in in vivo guinea-pigs
Q44437079Role of endogenous endothelin-1 in ethanol-induced gastric mucosal damage in humans
Q36756023Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat
Q71614224Somatostatin effectively prevents ethanol- and NSAID-induced gastric mucosal damage in rats
Q43699208The possible role of LTC4 in the pathogenesis of ethanol-induced gastric lesions in mice and their prevention by 5-lipoxygenase inhibitor AA-861, and leukotriene receptor antagonist FPL-55712.
Q39609733The role of leukotrienes in the pathogenesis of gastric ulceration

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